Increased Small Dense LDL and Decreased Paraoxonase Enzyme Activity Reveals Formation of an Atherogenic Risk in Streptozotocin-Induced Diabetic Guinea Pigs by Mutay Aslan, Filiz Ozcan, Ertan Kucuksayan

“…This study aimed to investigate LDL subfraction distribution as well as serum cholesteryl ester transfer protein (CETP), lecithin-cholesterol acyltransferase (LCAT), and paraoxonase (PON1) activity in streptozotocin-induced diabetic guinea pigs. Materials/Methods. Guinea pigs were given a single intraperitoneal (ip) injection of streptozotocin (STZ) and animals having fasting blood glucose levels greater than 200 mg/dl, were considered diabetic. …”
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A combined school survey and reactive case detection reveals minimal local transmission of malaria in the Highlands Region of Papua New Guinea by Osama Seidahmed, Serah Kurumop, Elizabeth Wawaga, Melvin Kualawi, Valentine Siba, Sharon Jamea, Yangta Ura, Leo Makita, William Pomat, Manuel W. Hetzel

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Acceptability of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine plus dihydroartemisinin-piperaquine in Papua New Guinea: a qualitative study by Elvin Lufele, Sophie Pascoe, Alice Mengi, Alma Auwun, Nalisa Neuendorf, John W. Bolnga, Moses Laman, Stephen J. Rogerson, Kamala Thriemer, Holger W. Unger

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Tuberculosis and HIV/AIDS-attributed mortalities and associated sociodemographic factors in Papua New Guinea: evidence from the comprehensive health and epidemiological surveillance system by Chalapati Rao, Willie Pomat, Tony Okely, Bang Nguyen Pham, Norah Abori, Vinson D Silas, Ronny Jorry

“…Objective Tuberculosis (TB) and HIV/AIDS are public health concerns in Papua New Guinea (PNG). This study examines TB and HIV/AIDS mortalities and associated sociodemographic factors in PNG.Method As part of a longitudinal study, verbal autopsy (VA) interviews were conducted using the WHO 2016 VA Instrument to collect data of 926 deaths occurred in the communities within the catchment areas of the Comprehensive Health and Epidemiological Surveillance System from 2018 to 2020.InterVA-5 cause of deaths analytical tool was used to assign specific causes of death (COD). …”
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Immune cell infiltration and modulation of the blood-brain barrier in a guinea pig model of tuberculosis: Observations without evidence of bacterial dissemination to the brain. by Amanda S Latham, Charlize E Geer, David F Ackart, Kristin N Weninger, Chase C Gross, Brendan K Podell, Randall J Basaraba, Julie A Moreno

“…To test this hypothesis, guinea pigs were exposed by aerosol to a laboratory and a clinical Mtb strain for 15 days. …”
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An Attenuated Cytomegalovirus Vaccine with a Deletion of a Viral Chemokine Gene Is Protective against Congenital CMV Transmission in a Guinea Pig Model by Michael P. Leviton, Juan C. Lacayo, K. Yeon Choi, Nelmary Hernandez-Alvarado, Andrew Wey, Mark R. Schleiss

“…To resolve this problem, this study employed guanosyl phosphoribosyl transferase (gpt) mutagenesis to generate a recombinant guinea pig CMV (GPCMV) with a knockout of a viral chemokine gene, GPCMV MIP (gp1). …”
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House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model by Patricia Ramos-Ramírez, Jielu Liu, Sofia Mogren, Joshua Gregory, Malin Noreby, Anne Petrén, Ying Lei, Henric Olsson, Marianne van Hage, Jukka Kervinen, Lars Hellman, Cecilia Andersson, Gunnar Nilsson, Mikael Adner

“…Methods. Guinea pigs were exposed intranasally to HDM or CDE for 4, 8, and 12 weeks, and airway histology was examined at each time point. …”
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Preparation and Characterization of Ink from Hibiscus sabdariffa, Curcuma longa and Sorghum vulgare by Idara U. Ntuen, Aniekan Effiong Akpakpan, Godwin Enin, Iniobong Sylvester Enengedi, Emaime Jimmy Uwantta, Edet William Nsi, Itoro E. Udo, Edidiong Emmanuel Ikpe, Ukana Davies Akpabio

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Change in hepatocyte nuclear-cytoplasmic ratio at nontuberculosis mycobacteria infection against the background of immunomodulator action by E. A. Kosobokov, T. S. Dudoladova

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Dry Matter Production, Nutrient Cycled and Removed, and Soil Fertility Changes in Yam-Based Cropping Systems with Herbaceous Legumes in the Guinea-Sudan Zone of Benin by Raphiou Maliki, Brice Sinsin, Anne Floquet, Denis Cornet, Eric Malezieux, Philippe Vernier

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Bacterial Toxin Fusion Proteins Elicit Mucosal Immunity against a Foot-and-Mouth Disease Virus Antigen When Administered Intranasally to Guinea Pigs by Sreerupa Challa, Steven M. Szczepanek, Debra Rood, Roger W. Barrette, Lawrence K. Silbart

“…In the current study, two different carrier/adjuvant approaches were used to augment mucosal immunity to the FMDV O1 BFS G-H loop epitope, in which the G-H loop was genetically coupled to the E. coli LT-B subunit and coexpressed with the LTA2 fragment (LTA2B-GH), or the nontoxic pseudomonas exotoxin A (ntPE) was fused to LTA2B-GH at LT-A2 to enhance receptor targeting. Only guinea pigs that were inoculated intranasally with ntPE-LTA2B-GH and LTA2B-GH induced significant anti-G-H loop IgA antibodies in nasal washes at weeks 4 and 6 when compared to ovalbumin or G-H loop immunized animals. …”
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Human Antibodies Can Cross Guinea Pig Placenta and Bind Its Neonatal Fc Receptor: Implications for Studying Immune Prophylaxis and Therapy during Pregnancy by Evi Budo Struble, Li Ma, Lilin Zhong, A. Lesher, Joel Beren, Pei Zhang

“…Here, we demonstrate that pregnant guinea pigs can transport human IgG transplacentally at the end of pregnancy. …”
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Anti-Interleukin-1 Beta/Tumor Necrosis Factor-Alpha IgY Antibodies Reduce Pathological Allergic Responses in Guinea Pigs with Allergic Rhinitis by Hu Wei-xu, Zhou Wen-yun, Zhu Xi-ling, Wen Zhu, Wu Li-hua, Wu Xiao-mu, Wei Hui-ping, Wang Wen-ding, He Dan, Xiang Qin, Hu Guo-zhu

“…This study aims to determine whether the combined blockade of IL-1β and TNF-α can alleviate the pathological allergic inflammatory reaction in the nasal mucosa and lung tissues in allergic rhinitis (AR) guinea pigs. Healthy guinea pigs treated with saline were used as the healthy controls. …”
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Growth Rate and Yield of Two Tomato Varieties (Lycopersicon esculentum Mill) under Green Manure and NPK Fertilizer Rate Samaru Northern Guinea Savanna by A. S. Isah, E. B. Amans, E. C. Odion, A. A. Yusuf

“…Field experiments were conducted in 2010-2011 and 2011-2012 dry seasons at the Research farm of the Institute for Agricultural Research, Samaru northern guinea savanna agro ecological zone of Nigeria to study growth rate and yield of tomato under green manure and NPK fertilizer rates. …”
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True Mangroves of Bintuni Bay, Indonesia with Special Notes on the Existence of Amyema mackayensis (Blakely) Danser and Brownlowia argentata Kurz by Ruhuddien Pandu Yudha, Ary Prihardhyanto Keim, Wawan Sujarwo, Mériadec Sillanpää, Charlie D. Heatubun

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Effects of Curcumin on Parameters of Myocardial Oxidative Stress and of Mitochondrial Glutathione Turnover in Reoxygenation after 60 Minutes of Hypoxia in Isolated Perfused Working Guinea Pig Hearts by Ermita I. Ibrahim Ilyas, Busjra M. Nur, Sonny P. Laksono, Anton Bahtiar, Ari Estuningtyas, Caecilia Vitasyana, Dede Kusmana, Frans D. Suyatna, Muhammad Kamil Tadjudin, Hans-Joachim Freisleben

“…We investigated the effects of curcumin on cardiac, myocardial, and mitochondrial parameters in perfused isolated working Guinea pig hearts. After preliminary experiments to establish the model, normoxia was set at 30 minutes, hypoxia was set at 60, and subsequent reoxygenation was set at 30 minutes. …”
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The Peptide Vaccine Combined with Prior Immunization of a Conventional Diphtheria-Tetanus Toxoid Vaccine Induced Amyloid β Binding Antibodies on Cynomolgus Monkeys and Guinea Pigs by Akira Yano, Kaori Ito, Yoshikatsu Miwa, Yoshito Kanazawa, Akiko Chiba, Yutaka Iigo, Yoshinori Kashimoto, Akira Kanda, Shinji Murata, Mitsuhiro Makino

“…Vaccination with a similar regimen was also performed on guinea pigs. The peptide vaccine induced anti-Aβ antibodies in cynomolgus monkeys and guinea pigs without chemical adjuvants, and excessive immune responses were not observed. …”
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Alternative approaches for monitoring and evaluation of lymphatic filariasis following mass drug treatment with ivermectin, diethylcarbamazine and albendazole in East New Britain Province, Papua New Guinea. by Krufinta Bun, Benedict Mode, Melinda Susapu, Joyceline Salo, Catherine Bjerum, Michael Payne, Daniel Tisch, Makoto Sekihara, Emanuele Giorgi, Gary J Weil, Peter U Fischer, Leanne Robinson, Moses Laman, Christopher L King

“…Before MDA, the population mean prevalence of LF in East New Britain Province (ENBP), Papua New Guinea, was estimated using population proportionate sampling (PPS, N = 30) to be 59/2,561 (2.3%) CFA positive and 14/2,561 (0.6%) Mf positive. …”
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Evaluating Cholinergic Receptor Expression in Guinea Pig Primary Auditory and Rostral Belt Cortices After Noise Damage Using [H]Scopolamine and [F]Flubatine Autoradiography by Taylor J. Forrest MS, Timothy J. Desmond MS, Mohamad Issa MD, Peter J. H. Scott PhD, Gregory J. Basura MD, PhD

“…We used [ 3 H]scopolamine and [ 18 F]flubatine binding to measure muscarinic acetylcholine receptor (mAChR) and nicotinic acetylcholine receptor (nAChR) expression, respectively, in guinea pig A1 and RB 3 weeks following unilateral, left ear noise exposure, and a temporary threshold shift in hearing. [ 3 H]Scopolamine binding decreased in right A1 and RB (contralateral to noise) compared to sham controls across all cortical layers. [ 18 F]Flubatine binding showed a nonsignificant upward trend in right A1 following noise but only significantly increased in right RB and 2 layers of left RB (ipsilateral to noise). …”
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El artivismo digital valenciano como estrategia feminista. Un caso de estudio de Tres Voltes Rebel by Alfonso Navarro Guinea

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