Epidemiology of Yellow Fever in Nigeria: Analysis of Climatic, Ecological, Socio-Demographic, and Clinical Factors Associated with Viral Positivity Among Suspected Cases Using Nati... by Stephen Eghelakpo Akar, William Nwachukwu, Oludare Sunbo Adewuyi, Anthony Agbakizua Ahumibe, Iniobong Akanimo, Oyeladun Okunromade, Olajumoke Babatunde, Chikwe Ihekweazu, Mami Hitachi, Kentaro Kato, Yuki Takamatsu, Kenji Hirayama, Satoshi Kaneko

“…Predictors of YFV positivity were the Jos Plateau, Derived/Guinea Savanah, and the Freshwater/Lowland rainforest compared to the Sahel/Sudan Savannah; dry season compared to rainy season; the hot dry or humid compared to the temperate, dry cool/humid climatic zone; 2019, 2020, 2021, 2022, and 2023 epidemic years compared to compared to 2017; first, third, and fourth quarters compared to the second; male sex compared to female; age group > = 15 years compared to < 15 years; working in outdoor compared to indoor settings; having traveled within the last two weeks; being of unknown vaccination status compared to being vaccinated; and vomiting. …”
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Diabetes Mellitus and HIV Infection among Newly Diagnosed Pulmonary Tuberculosis Patients in the North West Region of Cameroon: A Cross-Sectional Study by Leonard Fonkeng Sama, Sidoine Sadjeu, Thibau Flaurant Tchouangueu, Solange Dabou, Georges Ful Kuh, Omer Bebe Ngouateu, Michel Noubom

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Phosphate rebinding induces force reversal via slow backward cycling of cross-bridges by Robert Stehle

“…The aim was to explore the significance of force redevelopment kinetics (rate constant kTR) in cardiac myofibrils for the coupling between the Pi binding induced force reversal and the rate-limiting transition f– for backward cycling of cross-bridges from force-generating to non-force-generating states.MethodskTR and force generation of cardiac myofibrils from guinea pigs were investigated at 0.015–20 mM Pi. The observed force-[Pi], force-log [Pi], kTR-[Pi], and kTR-force relations were assessed with various single-pathway models of the cross-bridge cycle that differed in sequence and kinetics of reversible Pi release, reversible force-generating step and reversible rate-limiting transition. …”
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Prevalence and factors associated with modern contraceptive use among women of reproductive age in 20 African countries: a large population-based study by Robert Akparibo, Paschal Awingura Apanga, Maxwell Tii Kumbeni, Emmanuel Awine Ayamga, Mark B Ulanja

“…We used random effects meta-analysis to pool adjusted estimates across the 20 countries.Results The overall prevalence of modern CP use was 26% and ranged from 6% in Guinea to 62% in Zimbabwe. Overall, injectable (32%) was the most preferred method of CP, followed by oral pill (27%) and implants (16%). …”
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The Impact of Onchocerciasis Elimination Measures in Africa: A Systematic Review by Policarpo Ncogo, Christine Giesen, María Jesús Perteguer, Maria P. Rebollo, Rufino Nguema, Agustín Benito, Zaida Herrador

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Month and lunar cycle at calving influence and reproductive performance of a tropical buffalo herd by José Atilio Aranguren-Méndez, Rafael Román-Bravo, Ricardo A. Briceño-Rojas, Mauricio G. Briceño-Rojas, Eliani K. Núñez-Guerrero, Fernando P. Perea

“…As has been observed in other species (cattle, swine, and guinea pigs), the frequency of calving was significantly greater (p=0.0026) ∼2 days around the new moon (17.5%) and full moon (14.6%) than in the remaining 26 periods of the moon cycle (67.9%). …”
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Big Data-Driven Risk Analysis of Environmental Grievances in the Palm Oil Industry for Sustainable Decision-Making by Muhammad Syahmi Idris, Muhamad Shahrul Md Nor, Syazwani Ali, Norazman Mat Ali, Siew Wai Yoong, Mohd Nazli Mohd Nor, Mohd Suffian Mohd Muhili, Muhamad Fairus Noor Hassim

“…Predominantly deforestation, a total of 564 cases affecting ~66,716.23 ha in Indonesia, 312 cases affecting ~49,704.97 ha in Malaysia, 6 cases affecting ~43,500 ha in Papua New Guinea, and 2 cases in the Philippines. Network analysis reveals that the environmental grievances affected multiple companies, with WILMAR suppliers at the center. …”
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Effect of the Hydroethanolic Extract of Bixa orellana Linn (Bixaceae) Leaves on Castor Oil-Induced Diarrhea in Swiss Albino Mice by Michel Archange Fokam Tagne, Hypolyte Akaou, Paul Aimé Noubissi, Angèle Foyet Fondjo, Yaouke Rékabi, Henri Wambe, René Kamgang, Jean-Louis Essame Oyono

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Spatial autocorrelation and host anemone species drive variation in local components of fitness in a wild clownfish population by Marrot, Pascal, Fauvelot, Cécile, Berumen, Michael L, Srinivasan, Maya, Jones, Geoffrey P, Planes, Serge, Pujol, Benoit

“…Because of a long-term sampling effort, such information is available for the population of wild orange clownfish, Amphiprion percula, from Kimbe Island (Papua New Guinea). Previous work on the wild orange clownfish near Kimbe Island suggests that there is little adaptive potential and that variation in LRS is mainly driven by a breeder’s habitat. …”
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A prospective, multi-site, cohort study to estimate incidence of infection and disease due to Lassa fever virus in West African countries (the Enable Lassa research programme)-Stud... by Suzanne Penfold, Ayola Akim Adegnika, Danny Asogun, Olufemi Ayodeji, Benedict N Azuogu, William A Fischer, Robert F Garry, Donald Samuel Grant, Christian Happi, Magassouba N'Faly, Adebola Olayinka, Robert Samuels, Jefferson Sibley, David A Wohl, Manfred Accrombessi, Ifedayo Adetifa, Giuditta Annibaldis, Anton Camacho, Chioma Dan-Nwafor, Akpénè Ruth Esperencia Deha, Jean DeMarco, Sophie Duraffour, Augustine Goba, Rebecca Grais, Stephan Günther, Énagnon Junior Juvénal Prince Honvou, Chikwe Ihekweazu, Christine Jacobsen, Lansana Kanneh, Mambu Momoh, Aminata Ndiaye, Robert Nsaibirni, Sylvanus Okogbenin, Chinwe Ochu, Ephraim Ogbaini, Énagnon Parsifal Marie Alexandre Logbo, John Demby Sandi, John S Schieffelin, Thomas Verstraeten, Nathalie J Vielle, Anges Yadouleton, Emmanuel Koffi Yovo, Enable Protocol authorship group

“…<h4>Method</h4>We are conducting a prospective cohort study in Benin, Guinea, Liberia, Nigeria (three sites), and Sierra Leone from 2020 to 2023, with 24 months of follow-up. …”
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Mathematical Modelling and Analysis of Transmission Dynamics of Lassa Fever by E. A. Bakare, E. B. Are, O. E. Abolarin, S. A. Osanyinlusi, Benitho Ngwu, Obiaderi N. Ubaka

“…Clinical diseases, as well as high seroprevalence, have been documented in Nigeria, Sierra Leone, Liberia, Guinea, Ivory Coast, Ghana, Senegal, Upper Volta, Gambia, and Mali. …”
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Does macrolide use confer risk of out-of-hospital cardiac arrest compared with penicillin V? A Danish national case-crossover and case–time–control study by Lars Køber, Freddy Lippert, Charlotte Andersson, Peter E Weeke, Gunnar H Gislason, Frederik Boetius Hertz, Aksel Jensen, Jenny D Knudsen, Magnus Arpi, Christian Torp–Pedersen

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Isoleucine at position 137 of haemagglutinin acts as a mammalian adaptation marker of H9N2 avian influenza virus by Weiwei Ma, Chenyang Ren, Lin Shi, Bo Meng, Yali Feng, Ying Zhang

“…Moreover, the HA-T137I substitution in H9N2 avian influenza virus increased the guinea pig transmission efficiency. We also found that the HA-T137I substitution was critical for α2,6-linked sialic acid binding preference and HA activation and stability of H9N2 virus. …”
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Wildlife trade at the interface between deeply-rooted animal-based traditional medicine and unregulated harvesting of wild animals in West Africa by Stanislas Zanvo, Samson Dognimon, Chabi A. M. S. Djagoun, Jiroux Akpatchémè, Akomian Fortuné Azihou, Bruno Djossa, Bruno Djossa, Etotépé A. Sogbohossou, Brice Sinsin

“…We also found that the national wildlife trade in Benin was supplied from 80% (12/15) West African Economic and Monetary countries, and all the Economic Community of West African States (except Guinea-Bissau) in violation of national laws, CITES, and regional commitments to combat wildlife trafficking (e.g., the West African Strategy for Combatting Wildlife Crime). …”
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Functional and structural characterization of mouse Factor H-related B protein unveils a novel dimerization domain shared by FHR-B and FH by Adrián Martín-Ambrosio Doménech, Silvia González Sanz, Bárbara Márquez Tirado, Lucia Juana-López, Elena Goicoechea de Jorge, Santiago Rodríguez de Córdoba, Héctor Martín Merinero

“…It also competes with mouse Factor H (mFH) for binding to C3b-coated surfaces and disrupts mFH regulation in hemolysis assays with sheep and guinea pig erythrocytes. These functions are localized to the C-terminal region and are dependent on FHR-B dimerization. …”
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Integrated systems improve soil microclimate, soybean photosynthesis and growth by Luciana Maria da Silva, Eduardo Habermann, Kátia Aparecida de Pinho Costa, Adriano Carvalho Costa, João Antônio Gonçalves e Silva, Eduardo da Costa Severiano, Lourival Vilela, Fabiano Guimarães Silva, Alessandro Guerra da Silva, Bruno de Souza Marques, Fabrício Rodrigues, Carlos Alberto Martinez

“…Additionally, experiments were conducted to evaluate the effect of monocultures and previous integration between maize, three cultivars of Panicum maximum (Zuri, Tamani, and Quênia guinea grass) and Pigeon pea (Cajanus cajan cv. BRS Mandarim) on soil health, physiological aspects, and soybean production. …”
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The Global Burden of Polycystic Ovary Syndrome in Women of Reproductive Age: Findings from the GBD 2019 Study by Jiang B

“…The highest incidence rates were observed in the High-income Asia Pacific region, particularly in Japan and New Zealand, while the lowest rates were in Central Europe. Equatorial Guinea and Qatar exhibited the most pronounced increases in incidence and DALYs, attributed to urbanization and enhanced healthcare infrastructure. …”
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Mapping mycological ignorance – checklists and diversity patterns of fungi known for West Africa by Meike Piepenbring, Jose G. Maciá-Vicente, Jean Evans I. Codjia, Carola Glatthorn, Paul Kirk, Yalemwork Meswaet, David Minter, Boris Armel Olou, Kai Reschke, Marco Schmidt, Nourou Soulemane Yorou

“…According to data available in literature, knowledge on fungal richness ranges from 19 species (Guinea Bissau) to 1595 (Sierra Leone). In estimating existing species diversity, richness estimators and the Hawksworth 6:1 fungus to plant species ratio were used. …”
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Crimean-Congo haemorrhagic fever virus screening among African individuals in Spain: Lessons to learn by Helena Miriam Lorenzo Juanes, Amparo López-Bernus, Belen Vicente, Montserrat Alonso-Sardón, Beatriz Rodríguez Alonso, Josue Pendones Ulerio, Pedro Fernandez Soto, Juan Luis Muñoz Bellido, Antonio Muro, Moncef Belhassen-García

“…Forty-seven percent of the immigrant participants were from Equatorial Guinea; thus, the IgG seroprevalence among the Equatorial Guinean immigrant population (13/228) was 5.70 %. …”
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The Role of Thickening Agent Proportions in Optimizing Nanoemulsion Gel for Dermatophytosis Treatment by Zhang X, Wu CC, Jiang H, Zhao JF, Pan ZJ, Zheng Y

“…A series of α-pinene NGs (αNG1, αNG2, αNG3) containing 0.5%, 0.75% and 1% (w/w) Carbomer 940 were developed and evaluated for stability, rheological properties, and skin irritation; assessed for ex vivo skin permeation, deposition, and fluorescent imaging of drug distribution within skin layers; and tested in vivo for efficacy against Trichophyton rubrum infection in guinea pigs, with PAS (Periodic Acid–Schiff) staining confirming fungal clearance.Results: The steady-state skin flux rates of α-pinene over 24 hours were αNG1 (46.93± 2.52 μg/cm²/h) > αNG2 (26.01± 2.65 μg/cm²/h) > αNG3 (11.36± 1.69 μg/cm²/h). …”
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