Serum cytokines in ulcerative colitis of various clinical activity by Ye. A. Konovich, I. L. Halif, M. V. Shapina, K. E. Shirokikh

“…Substantial increase of IL-6 and IL-10 level was observed in severe form of UC (42,4±21,2 and 22,7±6,4 a pg/ml) as compared to the control group (1,5±1,8 and 5,2±4,1). In groups of patients, resistant and sensitive to conservative treatment, frequency of circulating IL-6 detection was 86,6 and 22,7% (р<0,05), level of IL-6 — 53,4±24,5 and 2,0±0,62 (р<0,05); detection rate of IL-10 — 66,6 and 9% (р<0,05), level of IL-10-31,6±7,4 and 7,1±6,9 (р<0,05) respectively. …”
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Correlation between Apelin and Some Angiogenic Factors in the Pathogenesis of Preeclampsia: Apelin-13 as Novel Drug for Treating Preeclampsia and Its Physiological Effects on Place... by Reham Z. Hamza, Abdel Aziz A. Diab, Mansour H. Zahra, Ali K. Asalah, Suzan M. M. Moursi, Najah M. Al-Baqami, Fawziah A. Al-Salmi, Mai S. Attia

“…The pregnant female rats were randomly divided into three groups: group 1 (normal pregnant group), group 2 (PE-induced group), injected subcutaneously with 75 mg L-NAME/kg bodyweight/day starting from day 9 to 20 of gestation, and group 3 (PE-induced group supplemented with apelin (PE + apelin)); PE induced as before and simultaneously subcutaneously injected with apelin-13 (6 × 10−8 mol/kg bodyweight/twice daily) beginning from day 6 to 20 of gestation. …”
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Baduanjin Training to Improve Parkinson's Disease Gait and Balance Function by DONG Shuangshuang, YAN Hongjie, DONG Qing, CAI Zenglin

“…Gait indicators and balance indicators were used to evaluate, analyze and compare the two groups of patients before the test and 3 weeks after the test.Results1) IDEEA gait indicators: there was no statistically significant difference in gait indicators between the two groups before the test (<italic>P</italic>&gt;0.05); after 3 weeks, compared with those before the test, the two gait indexes of cycle time and stride duration in the treatment group were improved, and the differences were statistically significant (<italic>P</italic>&lt;0.05), while the comparison of the gait index of the control group before and after the test, the difference was not statistically significant (<italic>P</italic>&gt;0.05); the cycle time and stride duration of the treatment group were respectively (1.30±0.32) s and (645.90±156.65) ms, which were better than those of the control group (1.56±0.38) s and (765.05±158.93) ms, and the differences were statistically significant (<italic>P</italic>&lt;0.05). 2) Balance index: there was no statistically significant difference in the balance index between the two groups before the test (<italic>P</italic>&gt;0.05); the scores and grades of balance test in the treatment group were improved after 3 weeks of the test compared with those before the test (<italic>P</italic>&lt;0.05), while there was no significant difference in the balance index of the control group before and after the test (<italic>P</italic>&gt;0.05); the balance test level of the treatment group was 1.00 (1.00, 2.20), which was better than the control group's 2.15 (1.00, 3.83), the difference was statistically significant (<italic>P</italic>&lt;0.05).ConclusionBaduanjin training can significantly improve the gait and balance ability of patients with mild to moderate PD.…”
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Synergistic Effect of Quercetin and α-Lipoic Acid on Aluminium Chloride Induced Neurotoxicity in Rats by Sooad Saud Al-Otaibi, Maha Mohamad Arafah, Bechan Sharma, Abdullah Salih Alhomida, Nikhat Jamal Siddiqi

“…The study consisted of eight groups, namely, Group 1: control rats, Group 2: rats receiving aluminium chloride 7 mg/kg body weight intraperitoneal route (i.p) for two weeks, Group 3: rats receiving quercetin 50 mg/kg body weight i.p. for two weeks, Group 4: rats receiving quercetin 50 mg/kg body weight followed by aluminium chloride 7 mg/kg body weight i.p. for two weeks, Group 5: rats receiving α-lipoic acid 20 mg/kg body weight i.p. for two weeks, Group 6: rats receiving lipoic acid 20 mg/kg body weight followed by aluminium chloride 7 mg/kg body weight i.p. for two weeks, Group 7: rats receiving α-lipoic acid 20 mg/kg body weight and quercetin 50 mg/kg body weight i.p. for two weeks, and Group 8: rats receiving α-lipoic acid 20 mg/kg body weight and quercetin 50 mg/kg body weight followed by aluminium chloride 7 mg/kg body weight i.p. for two weeks. …”
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Supporting primary care clinicians in caring for patients with alcohol use disorder: study protocol for Records for Alcohol Care Enhancement (RACE), a factorial four-arm randomized... by Kara M. Magane, Richard Saitz, Sarah Fielman, Marc R. LaRochelle, Christopher W. Shanahan, Christine A. Pace, Michael LaValley, Kaley Penington, Skylar Karzhevsky, Emily Hurstak

“…Methods PCPs from an urban safety-net hospital-based primary care clinic are randomized to one of four groups (1) EHR best practice advisory (BPA) and clinical decision support tools for unhealthy alcohol use (BPA), (2) BPA plus population health manager support, (3) BPA plus clinical care manager support, and (4) all three. …”
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Occupational physical activity and cardiovascular disease mortality in the United States, 1988–2019 by Tong Xia, Liwei Chen, Jian Li

“…., lifting, pushing, or pulling heavy objects) was assessed at baseline by a questionnaire and categorized into 4 groups [i.e., none, low, medium, and high]. CVD mortality was identified by International Classification of Diseases, Tenth Version (ICD–10) and collected by the National Death Index database. …”
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Interaction between Nuclear Receptor and Alpha-Adrenergic Agonist Subtypes in Metabolism and Systemic Hemodynamics of Spontaneously Hypertensive Rats by Sheryar Afzal, Munavvar Abdul Sattar, Ibrahim Albokhadaim, Ali Attiq, Mahmoud Kandeel, Aimi Syamima Abdul Manap, Sameer M. Alhojaily

“…The antioxidant potential and metabolic indices for these animals were also determined. Group I (WKY) and group II (SHR) were designated as normotensive control and hypertensive control, respectively. …”
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Codeveloping an Online Resource for People Bereaved by Suicide: Mixed Methods User-Centered Study by Edouard Leaune, Kushtrim Bislimi, Pauline Lau-Taï, Héloïse Rouzé, Benoit Chalancon, Laurène Lestienne, Pierre Grandgenevre, Margot Morgiève, Nathalie Laplace, Guillaume Vaiva, Julie Haesebaert, Emmanuel Poulet

“…The development stage of the resource lasted 18 months, from October 2021 to March 2023. A total of 9 focus groups, 1 online survey, 30 usability tests, and 30 semistructured interviews were performed. …”
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The effect of antifungal oral gel and ozonated water on tensile and compressive strength of two types of denture base materials: in-vitro study by Noha T. Alloush, Eman M. Ibraheem, Wessam M. Dehis

“…Patients and methods This study was carried out for two types of denture base materials; group I PMMA and group II Nylon or polyamide. Total samples for both groups were 160 and fabricated following American Dental Association specifications No.12 for assessing tensile and compressive strengths. …”
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State of spatial memory and antioxidant system activity of rats in the dynamics of development of blast-induced traumatic brain injury by Yu.V. Kozlova, H.S. Maslak, O.E. Abraimova, V.V. Koldunov, O.E. Khudyakov

“…The experiment was carried out on 67 albino male Wistar rats, which were randomly divided into three groups: I group – experimental (n=34), animals were subjected to inhalation anesthesia with halothane, fixed and was simulated blast-induced traumatic brain injury was simulated by generating a shock wave with an overpressure of 26.4±3.6 kPa, II group – sham (n=34), animals which were subjected only to inhalation anesthesia and fixation and III group – intact (n=34). …”
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Acid-Base Balance in Healthy Adults: Beneficial Effects of Bicarbonate and Sodium-Rich Mineral Water in a Randomized Controlled Trial: The BicarboWater Study by Katharina Mansouri, Theresa Greupner, Edda van de Flierdt, Inga Schneider, Andreas Hahn

“…Ninety-four healthy participants were divided into two groups: one consumed mineral water with a high bicarbonate and sodium content (HBS, n = 49) and the other consumed mineral water with a low bicarbonate and sodium content (LBS, n = 45). …”
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Adipose-derived mesenchymal stem cells combined with platelet-rich plasma are superior options for the treatment of osteoarthritis by Weijie He, Jie Zhao, Jiafei Liu, Fangxing Wang, Zhenyu Xu

“…Methods Eight- to nine-week-old male Sprague-Dawley (SD) rats were randomly assigned to two groups: (1) a normal control group (Group A) and (2) a model group. …”
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CHANGE IN TESTOSTERONE LEVELS IN ENDOSCOPIC OPERATIONS ON THE PROSTATE GLAND by E. A. Efremov, S. Yu. Shekhovtsov, D. S. Merinov, A. O. Butov, Yu. V. Kastrikin, T. I. Garaev

“…All patients were divided into 3 groups: Group I (14 patients) – patients with a normal preoperative level of testosterone (above 12 nmol/L), IIA group (17 patients) – patients with preoperative testosterone deficiency receiving HRT 2 weeks before surgery and during the entire period of postoperative follow-up and IIB group (16 patients) – patients with preoperative testosterone deficiency who did not receive therapy. …”
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Stability and Efficacy of Live-Attenuated Vibrio harveyi Vaccines Under Different Storage Conditions in Zebrafish (Danio rerio) Models by Mohd Hafiz Ngoo Muhamad-Sofie, Aslah Mohamad, Mohamad Azzam-Sayuti, Mohammad Noor Azmai Amal, Mohd Zamri-Saad, Md Shirajum Monir, Ina Salwany Md Yasin

“…A total of 1000 adult zebrafish (Danio rerio) (mean weight: 0.20±0.5 g) were divided into four groups. Groups 1, 2, and 3 were intraperitoneally injected with different LAVh vaccine storage (fresh, stale, and freeze-dried, respectively), while Group 4 received 0.01 M phosphate-buffered saline (PBS) and served as the unvaccinated control. …”
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Clinical Profile and Prescription Patterns in Culture-proven Enteric Fever in Children by Divya Priyadharshini, Mobill Clinton, Nandini Sethuraman, Mathrubootham Sridhar, Vidya Krishna

“…Mean fever defervescence time was 4.8 days in the single antibiotic group and 4.5 days in the combination group (<i>p</i> = 0.47), and in typhoid vs paratyphoid, it was 4.8 vs 3.3 days (<i>p</i> = 0.04). …”
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Evaluation of the impact of acidic medications and fluoride-containing mouthwash on the enamel surface using quantitative light-induced fluorescence, microhardness, and scanning el... by Saanya Bhasin, Simran Singh, Manuel Sebastian Thomas, Karuna Yarmunja Mahabala, Ramya Shenoy

“…The samples were divided into six groups: (i) Group DW_NF- samples immersed in distilled water with no fluoride exposure; (ii) Group DW_F- samples immersed in distilled water with intermittent fluoride exposure; (iii) Group VC_NF- samples treated with vitamin C only; (iv) Group VC_F- samples treated with vitamin C and fluoride mouthwash; (v) Group SB_NF- samples exposed to salbutamol inhaler with no fluoride exposure; (vi) Group SB_NF- samples exposed to salbutamol inhaler followed by fluoride exposure. …”
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Early embryonic thermal programming and post-hatch flavonoid (Scutellaria baicalensis) supplementation enhanced immune response markers in broiler chickens by Sadid Al Amaz, Md Ahosanul Haque Shahid, Rajesh Jha, Birendra Mishra

“…On embryonic day (ED) 12, the eggs were split into two groups: (1) Control, kept at standard temperature until hatch day (ED 21) and (2) Thermal Manipulation (TM), exposed to 38.5°C with 55% humidity for 12 h daily from ED 12 to ED 18. …”
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Urolithiasis complicated by chronic obstructive pyelonephritis in patients with concomitant diseases of the cardiovascular system by R. V. Royuk, S. K. Yarovoy, R. A. Khomov

“…Exacerbations of ChOP in patients of group I developed 1.5 times more often (once in 2.8-3 years) than in patients from the control group (on average after 18 months versus 28), and in group II almost annually (1 time in 13 months). …”
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The Effect of “Carvacrol” on Ischemia-Reperfusion Injury in the Skeletal Muscles of Rats by Barış Mardin, Abdullah Özer, Başak Koçak, Ayşegül Küçük, Mustafa Hakan Zor, Şaban Cem Sezen, Mustafa Kavutçu, Mustafa Arslan, Gürsel Levent Oktar

“…Methods: We planned our study with 18 rats, randomly divided into three groups: control group, I/R group, and I/R + Car group. In the control group, laparotomy was performed only, and blood and lower limb muscle tissue samples were taken. …”
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At-Home Immersive Virtual Reality Exergames to Reduce Cardiometabolic Risk Among Office Workers: Protocol for a Randomized Controlled Trial by Jing Zhao, Akitomo Yasunaga, Andrew T Kaczynski, Hyuntae Park, Yufeng Luo, Jiuling Li, Ai Shibata, Kaori Ishii, Shohei Yano, Koichiro Oka, Mohammad Javad Koohsari

“…The participants, who will be tested over a 12-week period, will be randomly assigned to one of three groups: (1) the VR exergame intervention group, (2) the regular physical activity control group, and (3) the nonexercise control group. …”
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