Relationship between Ca2+ and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells by Masahiko Kutsukake, Naoko Kuwabara, Yoshikazu Miyate, Kenzo Kudo, Shoko Goto, Eiichi Taira, Eiichi Tachikawa

“…In contrast, dibutyryl cAMP, a cell-permeable cAMP analog, greatly enhanced cortisol production in the normal or Ca2+-free medium and slowly caused Ca2+ influx into the cells. …”
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Optimization of In Vivo Studies by Combining Planar Dynamic and Tomographic Imaging: Workflow Evaluation on a Superparamagnetic Nanoparticles System by Maritina Rouchota, Alessio Adamiano, Michele Iafisco, Eirini Fragogeorgi, Irineos Pilatis, Gilles Doumont, Sébastien Boutry, Daniele Catalucci, Argyro Zacharioudaki, George C. Kagadis

“…Molecular imaging holds great promise in the noninvasive monitoring of several diseases with nanoparticles (NPs) being considered an efficient imaging tool for cancer, central nervous system, and heart- or bone-related diseases and for disorders of the mononuclear phagocytic system (MPS). …”
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Prevalence of antibiotic resistance genes in mining-impacted farmland environments by Hai-Yan Zou, Fang-Zhou Gao, Liang-Ying He, Min Zhang, You-Sheng Liu, Jun Qi, Guang-Guo Ying

“…When compared with the reference group, higher ARG abundances were detected in mining-affected farmland soils and vegetables, with great proportions of genes resistant to sulfonamides, chloramphenicols and tetracyclines. …”
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Alginate-based encapsulation of porcine placenta extract: Preparation, enteric sustained release, biological activities, and stability by Anukul Taweechaipaisankul, Nutthanit Thumrongsiri, Walailuk Chonniyom, Paweena Dana, Prattana Tanyapanyachon, Monthira Rattanatayarom, Wannapa Chinchoosak, Nattika Saengkrit

“…We found that placenta tissues prepared by freeze-drying could provide a great yield of protein derivatives and possessed 50.37 % anti-oxidative activity. …”
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Involvement of HLADQA1*05 in Patients with Inflammatory Bowel Disease Treated with Anti-TNF Drugs by Anna Pau, Ilaria Galliano, Elisa Barnini, Maddalena Dini, Antonio Pizzol, Alice Ponte, Stefano Gambarino, Pier Luigi Calvo, Massimiliano Bergallo

“…<i>Background</i>: Over the past decade, TNF inhibitors such as Infliximab and Adalimumab have become central to Inflammatory Bowel Diseases treatment, greatly enhancing patient outcomes. However, immunogenicity—where anti-drug antibodies diminish effectiveness—remains an issue, often requiring dose changes or combination therapies. …”
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Advancement of Pt and Pd-based catalysis for green, sustainable energy and bio-medical applications by Nithyadharseni Palaniyandy, Sekhosana Kutloano, Lakshmi Devaraj, Xolile Fuku, Sathish Sundar Dhilip Kumar

“…Platinum (Pt) and palladium (Pd) -based catalysts have sparked intense research interest for many important reactions in green energy and sustainable technologies such as key industrial petrochemical processes, fine chemical synthesis, environmental protection, renewable energy conversion and microbial, as their specific activity, stability and selectivity are greatly higher. However, the availability of low-cost electrodes/catalysts with high activity and stable electrochemical performance is crucial for the development of long-term and cost-effective green energy, environmental and sustainable technologies. …”
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Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway by Shubin Wang, Xiangjun Liu, Lu Xu, Jinyi Lang, Dengqun Liu, Dengqun Liu

“…Early DFO-induced iron depletion was able to maintain the p-STAT3 and p-ERK1/2 signaling pathways within the colonic epithelium at the early phase of colitis, but late DFO treatment inhibited the activity of these two pathways.DiscussionOur study demonstrated that the manipulation of iron depletion by DFO might greatly affect the outcomes of experimental colitis in a phase-dependent manner, which suggests that the balance of iron metabolism might be an effective therapeutic target for the clinical treatment of IBD patients.…”
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Hydrate-Based Methane Storage in Biodegradable Hydrogels Absorbing Dilute Sodium P-Styrenesulfonate Solution by Fangzheng Hua, Kang Tan, Jingyu Lv, Fei Wang, Mengting Sun

“…Therefore, the hydrogel-SS hybrid medium can serve as an effective and eco-friendly packing medium for methane hydrate storage tanks, which holds great application potential in hydrate-based methane storage technology.…”
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The impact of weather conditions in different years on the biochemical composition of linseed oil by G. A. Popova, N. B. Rogalskaya, N. V. Knyazeva, V. M. Trofimova, T. V. Shelenga, E. A. Porokhovinova, N. B. Brutch

“…The crop is widespread but the environment has a great effect on its fatty acid  biosynthesis.Materials and methods. …”
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Functional gastrointestinal disorders predictors in neonates and toddlers: A machine learning approach to risk assessment by Flavia Indrio, Elio Masciari, Flavia Marchese, Matteo Rinaldi, Gianfranco Maffei, Ilaria Gangai, Assunta Grillo, Roberta De Benedetto, Enea Vincenzo Napolitano, Isadora Beghetti, Luigi Corvaglia, Antonio Di Mauro, Arianna Aceti

“…Background: Functional Gastrointestinal Disorders (FGIDs) can pose a great burden on affected children, their families, and the healthcare system. …”
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Diet with high content of advanced glycation end products induces oxidative stress damage and systemic inflammation in experimental mice: protective effect of peanut skin procyanid... by Li Zhao, Xingxing Zhang, Langzhi He, Yubing Li, Yue Yu, Qun Lu, Rui Liu

“…Non-enzymatic glycation reaction in food can produce diet-derived advanced glycation end products (dAGEs), which have potential health risks. Thus, it is of great significance to find efficient substances to improve the negative effects induced by dAGEs on human health. …”
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Boosting effect of ultrasonication on the oxygen evolution reaction during zinc electrowinning by Guihong Han, Zhen Chen, Ningdan Cui, Shuzhen Yang, Yanfang Huang, Bingbing Liu, Hu Sun

“…Compared with that under silent conditions, the OER was greatly enhanced under ultrasonic conditions, and the overpotential reduction was found to be 108 mV at 35 °C at a current density of 50 mA cm−2. …”
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Study of fluidelastic instability in the streamwise and transverse directions through tube array under two-phase flow conditions using pressure effects by Sijiu Qi, Wei Tan, Ke Zhang, Yuancen Wang, Wenjing Lin, Peize Han, Guorui Zhu

“…Generally, FEI in the transverse direction of the tube occurs earlier than in the streamwise direction, and the intrinsic frequency of the tube as well as the way of tube distribution have a great influence. The mechanisms involved in inducing FEI need to be further investigated. …”
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Can infectious omphalitis in piglets be clinically diagnosed during the first three days of life? by Sophie Amalie Blirup-Plum, Henrik Elvang Jensen, Katrine Top Hartmann, Søren Saxmose Nielsen, Karen Pankoke, Mette Sif Hansen, Ken Steen Pedersen, Inge Larsen, Jens Peter Nielsen, John Elmerdahl Olsen, Egle Kudirkiene, Thomas Hartig Braunstein, Kristiane Barington

“…Abstract Background Globally, the increase in antimicrobial resistance is of great concern. In Denmark, the pig sector is accountable for the majority of antimicrobial usage in animals. …”
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Risk Factors Associated with Leishmaniasis in the Most Affected Provinces by Leishmania infantum in Morocco by Maryam Hakkour, Asmae Hmamouch, Mohamed Mahmoud El Alem, Abdelhakim Bouyahya, Abdelaali Balahbib, Abdelhak EL Khazraji, Hajiba Fellah, Abderrahim Sadak, Faiza Sebti

“…The risk study of the affected foci is of great value for the control and surveillance of this endemic disease, especially in the provinces where Leishmania infantum predominates. …”
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HALAL INDUSTRY IN KYRGYZSTAN: CURRENT STATE AND DEVELOPMENT PROSPECTS by Niyazali Turdalievich Aripov, Murat Zhuratovich Abdiev, Ahmad Syukran Baharuddin, Mirlanbek Baidusenovich Ubaidullaev

“… The halal industry in the Kyrgyz Republic faces a low level of development despite its great potential for economic growth and international market integration. …”
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Secondary neoplasms in survivors of pediatric acute lymphoblastic leukemia and lymphoblastic lymphoma: a single-center, retrospective study by Eri Ushida, Hidemi Toyoda, Atsushi Kohso, Yosuke Okumura, Kaori Niwa, Takahiro Ito, Mari Morimoto, Ryo Hanaki, Keishiro Amano, Shotaro Iwamoto, Takao Deguchi, Hiroki Hori, Masahiro Hirayama

“…Gliomas occurred significantly earlier than meningiomas (p = 0.047), and three patients died of secondary neoplasms (all gliomas).ConclusionsAs secondary gliomas occurred earlier than meningiomas and are associated with poor outcomes, physicians should take great pains to minimize their risk to improve long-term survival and quality of life.…”
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Radiocobalt-Labeling of a Polypyridylamine Chelate Conjugated to GE11 for EGFR-Targeted Theranostics by Lorraine Gaenaelle Gé, Mathias Bogetoft Danielsen, Aaraby Yoheswaran Nielsen, Mathias Lander Skavenborg, Niels Langkjær, Helge Thisgaard, Christine J. McKenzie

“…In this context, pairing an EGFR-targeting peptide with the emerging theranostic pair comprising the Auger electron emitter cobalt-58m (^58mCo) and the Positron Emission Tomography-isotope cobalt-55 (⁵⁵Co) would be of great interest for creating novel radiopharmaceuticals for prostate cancer and glioblastoma theranostics. …”
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Bridging brain and blood: a prospective view on neuroimaging-exosome correlations in HIV-associated neurocognitive disorders by Haixia Luo, Junzhuo Chen, Jiaojiao Liu, Wei Wang, Chuanke Hou, Xingyuan Jiang, Juming Ma, Fan Xu, Xire Aili, Zhongkai Zhou, Hongjun Li, Hongjun Li, Hongjun Li

“…Although combination antiretroviral therapy (cART) has greatly improved the prognosis for HIV patients, the incidence of HAND remains high, underscoring the urgent need to better understand its pathological mechanisms and develop early diagnostic methods. …”
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Cause analysis of gastric tube misplacement into the trachea using tetracaine gel as lubricant before gastrointestinal surgery: A case report and literature review (胃肠道术前应用丁卡因胶浆置胃管... by HE Shu (何姝), YU Chunguang (于春光), LI Jiaji (李佳霁), CUI Kaiyue (崔凯月), CHEN Kun (陈坤), DI Xiaowei (狄晓玮)

“…Occasionally, patients have atypical symptoms, which are easily ignored in clinical practice, bringing great safety risks to the operation. This paper reported a case of gastric tube misplacement into the trachea using tetracaine gel as lubricant before gastrointestinal surgery, analyzed the causes and summarized the preventive and nursing measures, and reviewed the new methods, new techniques and relatively rare complications of gastric tube placement. …”
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