Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

“…Another potent tool is the CRISPR/Cas9 technology, which has enabled targeted genome editing with higher accuracy and specificity and greatly advanced genome engineering in Plasmodium spp. …”
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Engineering dual-driven pro-angiogenic nanozyme based on porous silicon for synergistic acceleration of burn infected wound healing by Wei Duan, Yue Gao, Ruru Xu, Sheng Huang, Xueqian Xia, Jingwen Zhao, Longhuan Zeng, Qiaolin Wei, Jia-Wei Shen, Jianmin Wu, Yongke Zheng

“…Although nanozymes have made progress in inflammation modulation and antibacterial management, they often lack the ability in pro-angiogenesis, which greatly limits their functional application in the synergistic treatment of burn infected wounds. …”
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Geological Conditions and Sedimentary Models of Oligocene and Eocene Effective Source Rocks in the Northern Yinggehai Basin by Jianxiang Pei, Gaowei Hu, Zhipeng Huo, Zhihong Chen, Yabing Chen, Xiaofei Fu, Weihong Wang, Haiyu Liu, Yanan Wang, Jingshuang Luo, Guofei Chen

“…These studies make up for the serious deficiency of previous research and mean that there is great exploration potential for oil and gas in the northern Yinggehai Basin in China.…”
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Effect of Planting Density on the Agronomic Performance and Fruit Quality of Three Pineapple Cultivars (Ananas comosus L. Merr.) by Juan C. Neri, Jegnes Benjamín Meléndez Mori, Nuri Carito Vilca Valqui, Eyner Huaman Huaman, Roicer Collazos Silva, Manuel Oliva

“…Pineapple is a crop of great importance for the economic stability of a large number of Peruvians; however, in areas experiencing low degrees of technological intervention, farmers generally adopt low planting densities. …”
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Protective Effect of Conditioned Medium of Immortalized Human Stem Cells from Exfoliated Deciduous Teeth Against Hair Graying Caused by X-Ray Irradiation via Its Antioxidative Acti... by Yasuhiro Katahira, Eri Horio, Natsuki Yamaguchi, Jukito Sonoda, Miu Yamagishi, Satomi Miyakawa, Fumihiro Murakami, Hideaki Hasegawa, Izuru Mizoguchi, Takayuki Yoshimoto

“…Repetitive subcutaneous administrations of SHED-CM greatly suppressed the development of hair graying, when compared to control medium, resulting in reduced cutaneous expression of 8-hydroxy-2′-deoxyguanosine, the major product of DNA damage induced by reactive oxygen species. …”
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Controlled ovarian hyperstimulation with or without letrozole for fertility preservation in breast cancer patients: study protocol for a randomised controlled trial by Ping Li, Kun Wang, Qi Fan, Peng Sun, Yuhua Shi, Yanqiu Xie, Weifen Deng, Jiajing Kang

“…Introduction Multimodal anticancer therapies greatly damage the fertility of breast cancer patients, which raises urgent demand for fertility preservation. …”
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Very High Energy Solar Energetic Particle Events and Ground Level Enhancement Events: Forecasting and Alerts by N. Crosby, H. Mavromichalaki, O. Malandraki, M. Gerontidou, M. Karavolos, D. Lingri, P. Makrantoni, M. Papailiou, P. Paschalis, A. Tezari

“…Since the increased flux of such particles can be a major problem to technology in space and on Earth and pose a threat for human health, developing real time warning systems is of great importance. GLE Alert++ is a product, built by the Athens Cosmic Ray Group of the National and Kapodistrian University of Athens, that issues alerts when a GLE event starts to register and is based on ground‐based neutron monitor observations. …”
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Development and Evaluation of a Hydrometeorological Forecasting System Using the Coupled Ocean-Atmosphere-Wave-Sediment Transport (COAWST) Model by Jing Zou, Chesheng Zhan, Haiqing Song, Tong Hu, Zhijin Qiu, Bo Wang, Zhiqian Li

“…The 24 h forecasts, with a lead time of 24 hours, had high accuracy, while the 48 h and 72 h forecasts did not differ greatly in terms of performance. The distributions of bias between forecast and reanalysis data showed obvious differences between land and sea, with more forecasted precipitation and lower temperatures in land grids than in sea grids. …”
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The Surface Heat Flow of Mars at the Noachian–Hesperian Boundary by Javier Ruiz, Laura M. Parro, Isabel Egea-González, Ignacio Romeo, Julia Álvarez-Lozano, Alberto Jiménez-Díaz

“…The time period around the Noachian–Hesperian boundary, 3.7 billionyears ago, was an epoch when great geodynamical and environmental changes occurred on Mars. …”
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Strong volcanic-induced climatic shocks on historical Moselle wine production by F. C. Ljungqvist, F. C. Ljungqvist, F. C. Ljungqvist, B. Christiansen, L. Schneider, L. Schneider, P. Thejll

“…<p>In central and southern Europe, grapevine is a climate-sensitive agricultural product of great economic importance, both in historical times and today. …”
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Impacts of PM on Indoor Air Quality of Airport Terminal Buildings in a Core City of North China Plain by Yunting Zhao, Wenhui Zheng, Simeng Ma, Weikai Kong, Bo Han, Jian Yu

“…Abstract With the economic growth and globalization, a great deal of airports are being or planned to be constructed or retrofitted in China. …”
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Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer by Bin Han, Fang-yuan Mao, Yong-liang Zhao, Yi-pin Lv, Yong-sheng Teng, Mubing Duan, Weisan Chen, Ping Cheng, Ting-ting Wang, Zhong-yuan Liang, Jin-yu Zhang, Yu-gang Liu, Gang Guo, Quan-ming Zou, Yuan Zhuang, Liu-sheng Peng

“…The tumor microenvironment can suppress NK cell activity, and there is a great clinical interest in understanding whether modulating tumor-mediated NK cell suppression and/or boosting preexisting NK cell numbers in cancer patients is therapeutically viable. …”
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Review and Prospects of Key Technologies for Integrated Systems in Hydrogen Production from Offshore Superconducting Wind Power by Liufei Shen, Cheng Zhang, Feiyue Shan, Long Chen, Shuai Liu, Zhiqiang Zheng, Litong Zhu, Jinduo Wang, Xingzheng Wu, Yujia Zhai

“…However, due to the significant instability and intermittency of offshore wind power (OWP), this HPOSWP system can greatly affect the dynamic adaptability of the EWHP system, resulting in impure hydrogen production and compromising the safety of the LH₂ cooling system, and reduce the fitness of the integrated system for wind electricity–hydrogen heat multi-field coupling. …”
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Study on Variation of Surface Runoff and Soil Moisture Content in the Subgrade of Permeable Pavement Structure by Lijun Hou, Yuan Wang, Fengchun Shen, Ming Lei, Xiang Wang, Xiaochong Zhao, Shuling Gao, Abdullah Alhaj

“…The drier the soil, the greater the initial infiltration rate and the higher the soil moisture content after infiltration stabilization. Permeable roads can greatly alleviate the pressure of urban drainage and reduce the risk of storms and floods.…”
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Retrospective MRI analysis of 418 adult shoulder joints to assess the physiological morphology of the glenoid in a low-grade osteoarthritic population by Marc-Pascal Meier, Lars Erik Brandt, Mark-Tilmann Seitz, Paul Jonathan Roch, Katharina Jäckle, Ali Seif Amir Hosseini, Wolfgang Lehmann, Thelonius Hawellek

“…Therefore, the reconstruction of the physiological joint morphology is of great importance in shoulder joint preservation and replacement surgery. …”
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Natural Deep Eutectic Solvents as Green Alternatives for Extracting Bioactive Compounds from <i>Sideritis</i> Taxa with Potential Cosmetic Applications by Lamprini Zissi, Virginia D. Dimaki, Vassiliki S. Birba, Vassiliki C. Galani, Vassiliki Magafa, Sophia Hatziantoniou, Fotini N. Lamari

“…Results showed that water was not a good extraction solvent. Despite the great solvent-dependent differences, most NADEs, particularly the betaine–glycerol–glucose mixture (BGG4), exhibited comparable or even superior extraction efficiency and antioxidant activity compared to 70% ethanol. …”
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Evaluation of suitability of CO2 geologic storage in deep saline aquifers in Lindian area of Songliao Basin by Yongfa MA, Junling DONG, Xu WANG, Lan HE, Xuejun ZHOU, Ling LIU, Guang LIU, Zhenzhen SHI, Guannan CAO, Yan LIU, Xiuhai LI, Tian LIU, Tao ZHAN, Chang LI

“…Deep saline aquifers and cap beds are widely distributed in Lindian, Heilongjiang Province, offering favorable geological conditions and great potential for CO2 geological storage. However, due to the lack of oil exploration data, the high accuracy suitability evaluation has not been carried out. …”
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Construction of Pickering Double Emulsions Based on Xanthan Gum/Lysozyme Nanoparticles: Structure, Stability, and Co-Encapsulation of Epigallocatechin Gallate and β-Carotene by Yongpeng Yin, Denglin Luo, Lala Li, Xingguo Li, Mengyao Kang, Bakht Ramin Shah, Xianling Wei, Wei Xu

“…The low stability of water-in-oil-in-water (W₁/O/W₂) double emulsions greatly limits their applications. Therefore, in this study, W₁/O/W₂ Pickering double emulsions (PDEs) were prepared by a two-step emulsification method using polyglycerol polyricinoleate (PGPR) and xanthan gum/lysozyme nanoparticles (XG/Ly NPs) as lipophilic and hydrophilic emulsifiers, respectively. …”
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Structural and functional connectivity coupling as an imaging marker for bone metastasis pain in lung cancer patients by Jiahui Zheng, Chengfang Wang, Xiaoyu Zhou, Yu Tang, Lin Tang, Yong Tan, Jing Zhang, Hong Yu, Jiuquan Zhang, Daihong Liu

“…Moreover, CNN model built on individualized networks exhibited relatively great classification performance. Conclusion: Alterations in SC–FC coupling patterns may play a crucial role in the development and modulation of bone metastasis pain. …”
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Emerging challenges in aquaculture: Current perspectives and human health implications by M. Oghenebrorhie Ruben, A. Bolanle Akinsanola, M. Ekemini Okon, Teslim Shitu, I. Iretomiwa Jagunna

“…With the global population increasing and the demand for animal protein intensifying, aquaculture holds great potential as a sustainable food source. However, its contribution to global protein demand remains minimal, projected to decline to as low as 4% in the coming decades. …”
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