A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

“…In healthy tissues, binding to EpCAM and CD3 is greatly reduced by a novel, dual CAB selection, where each binding domain is independently blocked by the presence of physiological chemicals known as Protein-associated Chemical Switches (PaCS). …”
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Rapid estimation method of lithium battery state of health based on novel health feature by DONG Xiaohong, DONG Jinbo, WANG Mingshen, ZENG Fei, PAN Yi

“…The experimental results show that the proposed method and novel health feature can greatly reduce the calculation volume, and can achieve fast estimation of lithium battery SOH while ensuring prediction accuracy.…”
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Land Use Modeling and Predicted Ecosystem Service Value Under Different Development Scenarios: A Case Study of the Upper–Middle Yellow River Basin, China by Mingwei Ma, Yuhuai He, Yanwei Sun, Huijuan Cui, Hongfei Zang

“…Exploring the future ecosystem service value (<i>ESV</i>) of the upper–middle Yellow River Basin is of great significance to enhancing its ecological security and capacity. …”
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Analysis of the Heterogeneity of CD4+CD25+ T Cell TCR β CDR3 Repertoires in Breast Tumor Tissues, Lung Metastatic Tissues, and Spleens from 4T1 Tumor-Bearing BALB/c Mice by Teng Zhang, Fangfang Duan, Danhua Su, Long Ma, Jiezuan Yang, Bin Shi, Xiaoyan He, Rui Ma, Suhong Sun, Xinsheng Yao

“…The diversity and frequency of the CDR3 repertoires remained homogeneous in breast tumors and lung metastatic tissues and showed great heterogeneity in the spleens, which suggested that the breast tissues and lung metastatic tissues have characteristics of CD4+CD25+ T cells that relate to the tumor microenvironment. …”
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Sodium alginate ameliorates health in freshwater fish through gut-liver axis modulation under high carbohydrate diets by Wenlu Zhu, Huilin Zhang, Haitao Pan, Hao Zeng, Wenjun Wang, Yunfeng Liu, Zirui Wang, Qiubai Zhou, Chuanqi Yu

“…A combined analysis of metagenomics and the short-chain fatty acids (SCFAs) profile in the posterior intestinal digesta indicated that LA diets greatly increased concentration of acetic acid. This effect was accompanied by a concurrent reduction in the abundance of the species Marinobacter guineae relative to HC diets. …”
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Efficient hydrogen peroxide reduction in glutathione peroxidase cycle using cost-effective FeSe2 nanospheres by Saif Khan, Sundeep S. Bhagwath, Mohammad Rehan Ajmal, Intikhab A. Ansari, Mohtashim Lohani, Sanjaya Pavgada Raghunandana, Mohammad Luqman

“…Their exceptional efficiency makes them a strong candidate for practical applications in mitigating early browning caused by melanogenesis.ConclusionsFeSe2 nanozymes exhibit great promise as a biocatalyst for enhancing the shelf life of fruits and vegetables by reducing damage due to early melanogenesis. …”
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Fatigue Experiment and Failure Mechanism Analysis of Aircraft Titanium Alloy Wing–Body Connection Joint by Xianmin Chen, Shanshan Li, Yuanbo Liang, Shuo Wang, Liang Yan, Shichang Du

“…This result proves that the crack initiation life accounts for 95.19% of the full life cycle, which is much higher than the design requirement of 400,000 landings and takeoffs, indicating that the structural design of this test piece is on the conservative side and meets the requirements of aircraft operational safety. This research is of great significance in improving the safety and reliability of aircraft structures.…”
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TraxVBF: A hybrid transformer-xLSTM framework for EMG signal processing and assistive technology development in rehabilitation by Seyyed Ali Zendehbad, Athena Sharifi Razavi, Marzieh Allami Sanjani, Zahra Sedaghat, Saleh Lashkari

“…The fact that people with mobility impairments often have great difficulties in performing essential Activities of Daily Living (ADL) shows the importance of developing effective rehabilitation strategies. …”
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Optimizing Reversible Phase‐Transformation of FeS2 Anode via Atomic‐Interface Engineering Toward Fast‐Charging Sodium Storage: Theoretical Predication and Experimental Validation... by Wenxi Zhao, Yanbing Zhou, Hao Zhou, Xinqin Wang, Shengjun Sun, Xun He, Yongsong Luo, Binwu Ying, Yongchao Yao, Xiaoqing Ma, Xuping Sun

“…Abstract Sodium‐storage performance of pyrite FeS2 is greatly improved by constructing various FeS2‐based nanostructures to optimize its ion‐transport kinetics and structural stability. …”
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Patient perspectives on acromegaly disease burden: insights from a community meeting by Shruti N. Shah, Kevin C. J. Yuen, Vivien Bonert, Wenyu Huang, Jill Sisco, Chrystal Palaty, Kristen Dancel-Manning, Nidhi Agrawal

“…ObjectiveA profound mismatch between biological and symptom control in acromegaly creates a high disease burden despite achieving optimal biological control. There is a great need to learn more about the perspectives of patients living with acromegaly.MethodsAcromegaly Community hosted a virtual meeting in January 2021 and prepared a detailed report capturing participants’ input on acromegaly symptoms and current and future treatment approaches. …”
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Optimal Operation of Hydrogen Energy Coupling Integrated Energy System considering Green Certificate, Ladder-Type Carbon Joint Trading, and Dual-Incentive Demand Response by Jingying Yang, Xiu Ji, Meng Li, Dexin Li, Meiyue Li, Huanhuan Han, Jiqing Yu

“…Under the “carbon peak and carbon neutrality” goal, the construction of an efficient, low-carbon, and economical energy supply system is of great significance for advancing a dual carbon strategy. …”
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Exploring changes in metabolites and fecal microbiota of advanced gastric cancer based on plasma metabolomics and 16S rDNA sequencing by Xinyi Feng, Yu Zhang, Jun Feng, Zhongjun Li, Zhi Zhang, Lin Zhu, Ruoyu Zhou, Haibo Wang, Xiaojun Dai, Yanqing Liu

“…Metabolomics and 16S rDNA sequencing have shown great potential in elucidating complex mechanisms associated with diseases. …”
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The Nitrogen Fixation Characteristics of Terrestrial Nitrogen-Fixing Cyanobacteria and Their Role in Promoting Rice Growth by Lei Wu, Ji Dong, Jian Song, Yuan Zhu, Songhao Che, Xueting Qin, Yufeng Xu, Shiqi Tian, Dongchao Wang, Ping Tian, Xiaoshuang Wei, Xue Yang, Meiying Yang, Zhihai Wu

“…The total nitrogen content of rice leaves treated with GD2 increased by 48.73%, and the soluble protein content increased by 52.89%. GD2 has great potential as an excellent nitrogen-fixing cyanobacteria inoculant for rice, suitable for agricultural production. …”
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Fishing on Facebook: Using Social Media and Citizen Science to Crowd-Source Trophy Murray Cod by Matthew O’Connell, Dirk Spennemann, Jennifer Bond, R. Keller Kopf, Nicole McCasker, Paul Humphries

“…The use of social media to gather information from citizen scientists has great potential for data collection of such specimens. …”
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Proximity-based solutions for optimizing autism spectrum disorder treatment: integrating clinical and process data for personalized care by Annarita Vignapiano, Annarita Vignapiano, Francesco Monaco, Francesco Monaco, Stefania Landi, Luca Steardo, Carlo Mancuso, Claudio Pagano, Gianvito Petrillo, Alessandra Marenna, Martina Piacente, Stefano Leo, Carminia Marina Ingenito, Rossella Bonifacio, Benedetta Di Gruttola, Marco Solmi, Marco Solmi, Marco Solmi, Marco Solmi, Maria Pontillo, Giorgio Di Lorenzo, Giorgio Di Lorenzo, Alessio Fasano, Alessio Fasano, Alessio Fasano, Giulio Corrivetti, Giulio Corrivetti

“…Despite its prevalence, diagnosis can be lengthy, and access to appropriate treatment varies greatly. This project utilizes the power of Artificial Intelligence (AI), particularly Machine Learning (ML) and Deep Learning (DL), to improve Autism Spectrum Disorder diagnosis and treatment. …”
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Spatial-temporal evolution of habitat quality in tropical monsoon climate region based on “pattern–process–quality” – a case study of Cambodia by Kang Junmei, Yang Fengshuo, Wang Jun, Liu Yang, Fang Dengmao, Jiang Chengcheng

“…Exploring the coupling relationship of “pattern–process–quality” is conducive to understanding the internal mechanism of habitat quality change, and is of great significance for the function maintenance and sustainable management of regional ecosystems. …”
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A Comparative Analysis of Middle-of-Line Contact Architectures for Complementary FETs by Seung Kyu Kim, Johyeon Kim, Gunhee Choi, Kee-Won Kwon, Jongwook Jeon

“…The wrap-around-contact (WAC) structure, and the top metal source/drain (TMS) structure which is formed by increasing the contact depth of the top-placed NMOS, have in common that the external resistance is greatly reduced by enlarging the contact area and shortening the length of the high-resistance power VIA. …”
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Inferior Vena Cava Filter and Catheter-based Thrombolysis for Treatment of Massive Deep Vein Thrombosis: A Case Report by Sangram S Mangudkar, Sanket Genuji Shinde, Varun Bhaskar Lingneni, Satbir Kaur Malik, Sai Sirisha Nallani

“…A bilateral lower limb doppler ultrasound suggested thrombosis in the popliteal vein, great saphenous vein, deep femoral vein and common femoral vein in the left lower limb. …”
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Versatile and efficient fabrication of signal “turn‐on” lateral flow assay for ultrasensitive naked eye detection of small molecules based on self‐assembled fluorescent gold nanocl... by Mengjia Chao, Shengmei Tai, Minxin Mao, Wenbo Cao, Chifang Peng, Wei Ma, Yongwei Feng, Zhouping Wang

“…With the advantages of efficient fabrication, extraordinary sensitization, and good biocompatibility, our FONLFA platform is expected to have great potential in the rapid detection of various small molecules.…”
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An overview of RE-Mg-based alloys for hydrogen storage: Structure, properties, progresses and perspectives by Dongsheng Zhou, Chunling Zheng, Yanghuan Zhang, Hanfeng Sun, Peng Sheng, Xin Zhang, Jun Li, Shihai Guo, Dongliang Zhao

“…Furthermore, RE-Mg-based materials with low magnesium content and superlattice structure show great potential for application in the field of solid-state hydrogen storage. …”
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