Serum assisted PD-L1 aptamer screening for improving its stability by Yu Zhou, Haozhe Zhang, Yujing Ding, Changyuan Yu, Hao Li

“…With its improved stability, higher affinity and specificity, Apt-S1 holds great potential for applications in PD-L1 assisted cancer diagnosis and treatment. …”
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Efficiency of Disease and Disease Activity Diagnosis Models of Systemic Lupus Erythematosus Based on Protein Array Analysis by Yafei Zhao, Yuanyuan Qi, Xinran Liu, Yan Cui, Zhanzheng Zhao

“…This implied that they might greatly benefit clinical decisions and the treatment of SLE.…”
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Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions. by Zac Sandy, Zijuan Wang, Deepak Behera, Benjamin M Foster, Finlay A Martin, Kira Brüninghoff, Kathleen M Cain, Wolfgang Dörner, Maria Jose Cabello-Lobato, Josep V Forment, Matthew J Cliff, Igor Larrosa, Perdita Barran, Duncan L Smith, Henning D Mootz, Christine K Schmidt

“…This exquisite degree of sensitivity and specificity greatly improves upon previous screens aimed at identifying downstream non-covalent binders, or readers, of ISG15. …”
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Plasma Activated Water Assisted Ultrasonic Extraction of Polysaccharides from Yellow Cauliflower and Its Hypoglycemic Activity by Han ZHANG, Cheng YANG, Guiyun CHEN, Shuhong LI, Ye CHEN

“…Additionally, the HCP exhibited great hypoglycemic activity in vitro and the concentration-dependent. …”
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Impact Assessment of Grid-Connected Solar Photovoltaic Systems on Power Distribution Grid: A Case Study on a Highly Loaded Feeder in Ulaanbaatar Ger District by Turmandakh Bat-Orgil, Battuvshin Bayarkhuu, Bayasgalan Dugarjav, Insu Paek

“…The results show that the power loss of the feeder can be greatly reduced when the total installed capacity of the solar PV systems is selected optimally, and the location of the connection is at the end of the power distribution grid.…”
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Vision-Based Underwater Docking Guidance and Positioning: Enhancing Detection with YOLO-D by Tian Ni, Can Sima, Wenzhong Zhang, Junlin Wang, Jia Guo, Lindan Zhang

“…The proposed approach offered an accurate and efficient solution for underwater docking guidance and target detection, which is of great significance for improving the safety of docking.…”
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Changes in Cultivated Land and Its Effects on Vegetation and Evapotranspiration Characteristics in the Naoli River Basin by YIN Jian, XIA Ruici, WEI Danqi, DING Yi, JIANG Hongtao, LUO Xinyuan

“…The Naoli River Basin is located in the hinterland of the Sanjiang Plain and is an important grain production area in China.In recent years,with the guarantee of food security and the adjustment of regional agricultural structure in China,there have been significant changes in land use,such as cultivated land expansion and planting structure adjustment.Therefore,identifying changes in cultivated land and their ecological effects is of great significance for regional ecological protection.This study analyzed changes in land use from 1980 to 2020 and then estimated their ecological impact using the ecological impact index of cultivated land change based on normalized difference vegetation index (NDVI) and actual evapotranspiration data.In addition,changes in evapotranspiration were estimated to determine the degree of water consumption.The results show that:① the area of cultivated land in the basin has increased significantly from 7 273.22 km² to 15 313.62 km² over the past 40 years,an increase of 110.55%,mainly due to the reclamation of forests and wetlands;② in the past 20 years,there has been a significant conversion between paddy fields and dry land,with a greater increase in conversion from dry land to paddy fields;③ From 2000 to 2020,both NDVI and evapotranspiration in the basin showed an increasing trend,with an increased amplitude of 8.15% and 18.58%,respectively.The increase in NDVI in cultivated areas mainly occurs during the crop growing season,while the contribution of non-growing seasons to NDVI change is low;④ different types of changes in cultivated land have varying contributions to the NDVI and annual evapotranspiration in the basin.Returning cultivated land to forest has contributed to ecological protection and reduced water consumption.Although the reclamation of wetlands has increased NDVI during the growing season,it has also increased water consumption in the basin.The conversion from paddy fields to dry land is beneficial for water conservation in the basin,while the conversion from dry land to paddy fields increases evaporation and water consumption,potentially posing a risk to water resource security.…”
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Triglyceride-glucose index in predicting the risk of new-onset diabetes in the general population aged 45 years and older: a national prospective cohort study by Yingqi Shan, Qingyang Liu, Tianshu Gao

“…Triglyceride glucose index (TyG) is simple, reliable and reproducible in detecting IR, and has great advantages in predicting the risk of diabetes. …”
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Analysis of Waves in the Oman Sea Using Numerical Software and Field Data by Homayun Kalantari, Kamran Lari, Afshin Mohseni Arasteh, Masoud Torabi Azad

“…Accurate prediction of wave parameters is of great significance for marine and coastal operations. …”
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Modern Pedagogical Approaches in the System of Engineering Education by L. V. Orinina, I. V. Kashuba, N. V. Dyorina, E. V. Rabina

“…At present, the general issues of humanization and pedagogical and methodological support of the educational process are of great importance in light of the need to increase the academic mobility of university graduates who choose to work at universities. …”
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Proportion of Chromosomal Disorders and Their Patterns among Births with Congenital Anomalies in Africa: A Systematic Review and Meta-Analyses by Teshome Gebremeskel Aragie, Girma Seyoum Gedion

“…Worldwide, surveys have shown that the frequency of chromosomal disorders among births with congenital anomalies varies greatly from country to country. It is well known that chromosomal disorders are an important cause of premature death or life-long disability; however, the absence of local epidemiological data on their birth prevalence and outcomes impedes policy and service development in many countries and continents. …”
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Performance Degradation of Subsea Shield Tunnel Segment Accounting for Concrete Strength Loss and Steel Bar Corrosion by Jiaqi Guo, Weiling Yang, Chong Xu, Bo Peng, Jinhai Lin, Yuan Qian

“…When steel bars corrode for 120 days, the outer cracks continue to extend, and the concrete around the inner steel bars just begin to crack initiation; when corrode for 20 years, the length of the inner cracks gradually exceeds that of the outer cracks, and the inner cracks initiating from different steel bars coalesce with each other and form a continuous failure surface, causing great serious damage to the segment. Due to the difference in concrete strength, for the outer layer, the evolution processes of steel bar corrosion-induced cracks show the characteristics of early initiation, slow propagation, and late coalescence, and those for the inner layer have the characteristics of late initiation, rapid propagation, and early coalescence. …”
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Mechanical properties of double-solid waste cement stabilized Macadam by Rui Tao, Xuejiao Cheng, Yong Jin, Jiangang Qiao, Xue Zhang, Daehyeon Kim, Jinjie Liu

“…At the same time, with the economy development, the increase of solid waste, such as waste tires and construction waste, has caused great pressure on the ecological environment. In order to ensure better mechanical properties and shrinkage resistance of the cement stabilized macadam on the basis of full use of solid waste. …”
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Similar Conditions With Opposite Effects: Predation‐Risk Effects on Prey Abundance Are Highly Contingent by Scott D. Peacor, Clayton E. Cressler, Kevin L. Pangle, Alexandra V. Rafalski, Chao Song, Earl E. Werner

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Biocompatibility of new cement based capping material prepared from eggshell and biopolymer (chitosan). by Hemn M. Sarmamy, Dara H. Saeed

“…For the Experimental group, MTA and Biodentine group there was great similarity in the tissue reaction when comparedwith control group. …”
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Teaching methods for critical thinking in health education of children up to high school: A scoping review. by Anna Prokop-Dorner, Aleksandra Piłat-Kobla, Magdalena Ślusarczyk, Maria Świątkiewicz-Mośny, Natalia Ożegalska-Łukasik, Aleksandra Potysz-Rzyman, Marianna Zarychta, Albert Juszczyk, Dominika Kondyjowska, Agnieszka Magiera, Małgorzata Maraj, Dawid Storman, Sylwia Warzecha, Paulina Węglarz, Magdalena Wojtaszek-Główka, Wioletta Żabicka, Małgorzata M Bała

“…Many educational interventions did not address the development of critical thinking skills in a comprehensive manner, and the significance of critical thinking varied greatly. Interventions in which critical thinking had high and very high significance applied mainly problem-solving methods and involved pupils' activity. …”
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The oncogenic roles of GPR176 in ovarian cancer: a molecular target for aggressiveness and gene therapy by Ning Yang, Wen-jing Yun, Zheng-guo Cui, Hua-chuan Zheng

“…Background At present, the discovery of new biomarkers is of great significance for the early diagnosis, treatment and prognosis assessment of ovarian cancer. …”
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A Co-Evolutionary Genetic Algorithm Approach to Optimizing Deep Learning for Brain Tumor Classification by Abdelmgeid A. Ali, Mohamed T. Hammad, Hassan S. Hassan

“…These results outperform cutting-edge methods, offering a rapid and reliable method for brain tumor classification. This approach has great potential to support radiologists and physicians in making timely and accurate diagnoses.…”
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Secretory Carcinoma of the Parotid: Making the Correct Diagnosis of a Rare Salivary Gland Carcinoma When Molecular Biology Testing Is Not Available by Nelson Montalvo, David Galarza, Ligia Redrobán

“…Moreover, in low-resource settings where molecular analysis is not available, being familiar enough with the histology of this tumor and using the immunoprofile as a key tool for differential diagnosis would be of great importance in establishing the correct diagnosis. …”
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Prediction of Bench Blasting Vibration on Slope and Safety Threshold of Blasting Vibration Velocity to Undercrossing Tunnel by Li He, Dongwang Zhong, Yihe Liu, Kun Song

“…The research results have great guiding significance to similar cooperative blasting excavation engineering for high slope and adjacent tunnel with safety and efficiency.…”
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