Showing 21 - 40 results of 112 for search '"Glycan"', query time: 0.05s Refine Results
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    Recent Advances in Electrochemical Glycobiosensing by Germarie Sánchez-Pomales, Rebecca A. Zangmeister

    Published 2011-01-01
    “…Biosensors based on electrochemical transduction mechanisms have recently made advances into the field of glycan analysis. These glyco-biosensors offer simple, rapid, sensitive, and economical approaches to the measurement need for rapid glycan analysis for biomarker detection, cancer and disease diagnostics, and bioprocess monitoring of therapeutic glycoproteins. …”
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  9. 29

    Expanding the structural resolution of glycosylation microheterogeneity in therapeutic proteins by salt-free hydrophilic interaction liquid chromatography tandem mass spectrometry by Yutian Gan, Steffen Lippold, John Stobaugh, Christian Schöneich, Feng Yang

    Published 2024-12-01
    “…Therefore, it is important to identify and quantify glycans during drug development. Glycosylation is a highly complex post-translational modification (PTM) due to its structural heterogeneity, i.e. glycosylation site occupancy, glycan compositions, modifications, and isomers. …”
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  10. 30

    Monovalent Lectin Microvirin Utilizes Hydropathic Recognition of HIV-1 Env for Inhibition of Virus Cell Infection by Bibek Parajuli, Kriti Acharya, Harry Charles Bach, Shiyu Zhang, Cameron F. Abrams, Irwin Chaiken

    Published 2025-01-01
    “…To better understand the nature of the MVN-Env glycan interaction, we used mutagenesis to evaluate the residue contributions to the mannobiose binding site of MVN that are important for Env gp120 glycan binding. …”
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  11. 31

    Compositional data analysis enables statistical rigor in comparative glycomics by Alexander R. Bennett, Jon Lundstrøm, Sayantani Chatterjee, Morten Thaysen-Andersen, Daniel Bojar

    Published 2025-01-01
    “…Abstract Comparative glycomics data are compositional data, where measured glycans are parts of a whole, indicated by relative abundances. …”
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  12. 32

    In-situ profiling of glycosylation on single cells with surface plasmon resonance imaging by Xiaoyin Liu, Jinbiao Ma, Yunrui Zhang, Yi Xu, Yunxiao Wang, Dehong Yang, Di Wang, Qingjun Liu, Fenni Zhang

    Published 2025-01-01
    “…Here, we present a direct optical method to investigate and quantify the glycan expression on single cells based on lectin-glycan kinetic quantification with plasmonic imaging. …”
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    Identification of novel fructo-oligosaccharide bacterial consumers by pulse metatranscriptomics in a human stool sample by Catherine Prattico, Emmanuel Gonzalez, Lharbi Dridi, Shiva Jazestani, Kristin E. Low, D. Wade Abbott, Corinne F. Maurice, Bastien Castagner

    Published 2025-01-01
    “…As more research supports the use of glycans as prebiotics for therapeutic applications, the need to identify the gut bacteria that metabolize glycans of interest increases. …”
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  14. 34

    Deglycosylation of Excretory-Secretory Antigens of the Second-Stage Larvae of Toxocara cati Improves Its Efficacy in the Diagnosis of Human Toxocariasis by Ali Pouryousef, Bahador Sarkari, Amir Mootabi Alavi, Mostafa Omidian, Fattaneh Mikaeili

    Published 2023-01-01
    “…One of the significant challenges in the serodiagnosis of human toxocariasis is the cross-reaction of Toxocara antigens with other parasites due to their relatively similar glycan structures. Removing the glycan structure from Toxocara excretory-secretory (TES) antigens may increase the efficacy of these antigens in the diagnosis of toxocariasis. …”
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  15. 35

    Ribitol and ribose treatments differentially affect metabolism of muscle tissue in FKRP mutant mice by Marcela P. Cataldi, Qi L. Lu

    Published 2025-01-01
    “…Recent studies have delineated the glycan chain structure of the matriglycan and the pathway with key components identified. …”
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  16. 36

    Galectins as New Prognostic Markers and Potential Therapeutic Targets for Advanced Prostate Cancers by Diego J. Laderach, Lucas Gentilini, Felipe M. Jaworski, Daniel Compagno

    Published 2013-01-01
    “…Several groups investigated protein-glycan interactions as critical factors for crosstalk between prostate tumors and their microenvironment. …”
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  17. 37

    Identification of nine mammal monosaccharides by solid-state nanopores by Yunze Sun, Zhuang Mi, Xiaoyu Chen, Jian-Jun Li, Jun Lu, Xinyan Shan, Xinghua Lu, Yuguang Du

    Published 2024-12-01
    “…Abstract Glycans, nucleic acids and proteins are three major classes of natural biopolymers. …”
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  18. 38

    Sarcolemma resilience and skeletal muscle health require O-mannosylation of dystroglycan by Jeffrey M. Hord, Sarah Burns, Tobias Willer, Matthew M. Goddeeris, David Venzke, Kevin P. Campbell

    Published 2025-01-01
    “…Extensive post-translational processing and O-mannosylation are required for α-DG to bind ECM proteins, which is mediated by a glycan structure known as matriglycan. O-mannose glycan biosynthesis is initiated by the protein O-mannosyltransferase 1 (POMT1) and POMT2 enzyme complex and leads to three subtypes of glycans called core M1, M2, and M3. …”
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    Exploring the Structural Diversity and Biotechnological Potential of the Rhodophyte Phycolectome by Éllen F. Rodrigues, Flavia Alves Verza, Felipe Garcia Nishimura, Renê Oliveira Beleboni, Cedric Hermans, Kaat Janssens, Maarten Lieven De Mol, Paco Hulpiau, Mozart Marins

    Published 2024-12-01
    “…Lectins are non-covalent glycan-binding proteins found in all living organisms, binding specifically to carbohydrates through glycan-binding domains. …”
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  20. 40

    A Nanoparticle Comprising the Receptor-Binding Domains of Norovirus and <i>Plasmodium</i> as a Combination Vaccine Candidate by Ming Xia, Pengwei Huang, Frank S. Vago, Wen Jiang, Xi Jiang, Ming Tan

    Published 2025-01-01
    “…The protruding (P) domain of norovirus VP1 and the αTSR domain of the circumsporozoite protein (CSP) of <i>Plasmodium</i> sporozoite are the glycan receptor-binding domains of the two pathogens for host cell attachment, making them excellent targets for vaccine development. …”
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