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Genetic control of N-glycosylation of human blood plasma proteins
Published 2023-06-01Subjects: Get full text
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Alcohol induces α2‐6sialo mucin O‐glycans that kill U937 macrophages mediated by sialic acid‐binding immunoglobulin‐like lectin 7 (Siglec 7)
Published 2025-01-01Subjects: Get full text
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Impact of different pathogen classes on the serum N-glycome in septic shock
Published 2025-01-01Subjects: Get full text
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Extracellular vesicles display distinct glycosignatures in high-grade serous ovarian carcinoma
Published 2025-01-01Subjects: “…N-glycans…”
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Monosaccharide coatings on nanoparticles affect protein corona formation but not the interaction with their binding receptor
Published 2025-01-01Subjects: Get full text
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Site-specific N-glycosylation characterization and allergenicity analysis of globulin-1 S allele from wheat
Published 2023-09-01Subjects: Get full text
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Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression
Published 2025-02-01Subjects: Get full text
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Recent Advances in Electrochemical Glycobiosensing
Published 2011-01-01“…Biosensors based on electrochemical transduction mechanisms have recently made advances into the field of glycan analysis. These glyco-biosensors offer simple, rapid, sensitive, and economical approaches to the measurement need for rapid glycan analysis for biomarker detection, cancer and disease diagnostics, and bioprocess monitoring of therapeutic glycoproteins. …”
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Expanding the structural resolution of glycosylation microheterogeneity in therapeutic proteins by salt-free hydrophilic interaction liquid chromatography tandem mass spectrometry
Published 2024-12-01“…Therefore, it is important to identify and quantify glycans during drug development. Glycosylation is a highly complex post-translational modification (PTM) due to its structural heterogeneity, i.e. glycosylation site occupancy, glycan compositions, modifications, and isomers. …”
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Monovalent Lectin Microvirin Utilizes Hydropathic Recognition of HIV-1 Env for Inhibition of Virus Cell Infection
Published 2025-01-01“…To better understand the nature of the MVN-Env glycan interaction, we used mutagenesis to evaluate the residue contributions to the mannobiose binding site of MVN that are important for Env gp120 glycan binding. …”
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Compositional data analysis enables statistical rigor in comparative glycomics
Published 2025-01-01“…Abstract Comparative glycomics data are compositional data, where measured glycans are parts of a whole, indicated by relative abundances. …”
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In-situ profiling of glycosylation on single cells with surface plasmon resonance imaging
Published 2025-01-01“…Here, we present a direct optical method to investigate and quantify the glycan expression on single cells based on lectin-glycan kinetic quantification with plasmonic imaging. …”
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Identification of novel fructo-oligosaccharide bacterial consumers by pulse metatranscriptomics in a human stool sample
Published 2025-01-01“…As more research supports the use of glycans as prebiotics for therapeutic applications, the need to identify the gut bacteria that metabolize glycans of interest increases. …”
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Deglycosylation of Excretory-Secretory Antigens of the Second-Stage Larvae of Toxocara cati Improves Its Efficacy in the Diagnosis of Human Toxocariasis
Published 2023-01-01“…One of the significant challenges in the serodiagnosis of human toxocariasis is the cross-reaction of Toxocara antigens with other parasites due to their relatively similar glycan structures. Removing the glycan structure from Toxocara excretory-secretory (TES) antigens may increase the efficacy of these antigens in the diagnosis of toxocariasis. …”
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Ribitol and ribose treatments differentially affect metabolism of muscle tissue in FKRP mutant mice
Published 2025-01-01“…Recent studies have delineated the glycan chain structure of the matriglycan and the pathway with key components identified. …”
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Galectins as New Prognostic Markers and Potential Therapeutic Targets for Advanced Prostate Cancers
Published 2013-01-01“…Several groups investigated protein-glycan interactions as critical factors for crosstalk between prostate tumors and their microenvironment. …”
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Identification of nine mammal monosaccharides by solid-state nanopores
Published 2024-12-01“…Abstract Glycans, nucleic acids and proteins are three major classes of natural biopolymers. …”
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Sarcolemma resilience and skeletal muscle health require O-mannosylation of dystroglycan
Published 2025-01-01“…Extensive post-translational processing and O-mannosylation are required for α-DG to bind ECM proteins, which is mediated by a glycan structure known as matriglycan. O-mannose glycan biosynthesis is initiated by the protein O-mannosyltransferase 1 (POMT1) and POMT2 enzyme complex and leads to three subtypes of glycans called core M1, M2, and M3. …”
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Exploring the Structural Diversity and Biotechnological Potential of the Rhodophyte Phycolectome
Published 2024-12-01“…Lectins are non-covalent glycan-binding proteins found in all living organisms, binding specifically to carbohydrates through glycan-binding domains. …”
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A Nanoparticle Comprising the Receptor-Binding Domains of Norovirus and <i>Plasmodium</i> as a Combination Vaccine Candidate
Published 2025-01-01“…The protruding (P) domain of norovirus VP1 and the αTSR domain of the circumsporozoite protein (CSP) of <i>Plasmodium</i> sporozoite are the glycan receptor-binding domains of the two pathogens for host cell attachment, making them excellent targets for vaccine development. …”
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