Non-pharmacological interventions for primary hypertension: a systematic review and network meta-analysis protocol by Tao Xu, Fan-rong Liang, Qifu Li, Taipin Guo, Ziwen Chen, Yun-Jie Shu, Xueli Zhou

“…Introduction Primary hypertension (PH) affects over one billion individuals globally, yet less than 30% achieve controlled blood pressure (BP) with medication. …”
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Multi-decade northward shift of loggerhead sea turtle pelagic habitat as the eastern North Pacific Transition Zone becomes more oligotrophic by Dana K. Briscoe, Dana K. Briscoe, Larry B. Crowder, George H. Balazs, Jeffrey A. Seminoff, Alberto Abreu, Catherine A. Lee Hing, Masanori Kurita, Masanori Mori, Denise M. Parker, Marc R. Rice, Tomomi Saito, Bianca S. Santos, Calandra N. Turner Tomaszewicz, Noah Yamaguchi, Jeffrey J. Polovina

“…The North Pacific Transition Zone (NPTZ) is known as a global marine hotspot for many endangered and commercially significant highly mobile marine species. …”
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Unveiling <i>DENND2D</i> as a Novel Prognostic Biomarker for Prostate Cancer Recurrence: From Gene to Prognosis by Chi-Fen Chang, Lih-Chyang Chen, Yei-Tsung Chen, Chao-Yuan Huang, Chia-Cheng Yu, Victor C. Lin, Te-Ling Lu, Shu-Pin Huang, Bo-Ying Bao

“…<b>Background:</b> Prostate cancer is a major global health burden, with biochemical recurrence (BCR) following radical prostatectomy affecting 20–40% of patients and posing significant challenges to prognosis and treatment. …”
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Autophagy activation in response to cigarette smoke: Exploring the disparity in laryngeal cancer incidence and outcomes between sexes in South Korea by Min Ji Kim, Jisu Hong, Hyo Won Chang, Yun-Hee Lee, Jun-Pyo Myong, Ah Ra Jung, Yoon Se Lee, Minsu Kwon

“…Introduction: Laryngeal cancer (LC) presents a significant health challenge globally, with smoking being a major risk factor. Interestingly, LC incidence in females is significantly lower than in males; however, female smokers are more likely to develop Reinke edema (RE) than LC. …”
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Investigating shared risk variants and genetic etiology between Alzheimer’s disease and three stress-related psychiatric disorders: a large-scale genome-wide cross-trait analysis by Weijia Dang, Tianqi Hao, Ning Li, Hualin Zhang, Ziqi Li, Hongmei Yu, Yalu Wen, Deqiang Zheng, Long Liu

“…By leveraging summary statistics from genome-wide association studies, we investigated global genetic correlations using linkage disequilibrium score regression, genetic covariance analysis, and high-definition likelihood. …”
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Identification of promising SARS-CoV-2 main protease inhibitor through molecular docking, dynamics simulation, and ADMET analysis by Ganesh Sharma, Neeraj Kumar, Chandra Shekhar Sharma, Taha Alqahtani, Yewulsew Kebede Tiruneh, Sharifa Sultana, Gabriel Vinícius Rolim Silva, Gabriela de Lima Menezes, Magdi E. A. Zaki, Jonas Ivan Nobre Oliveira

“…Abstract The COVID-19 pandemic caused by SARS-CoV-2 continues to pose a major challenge to global health. Targeting the main protease of the virus (Mpro), which is essential for viral replication and transcription, offers a promising approach for therapeutic intervention. …”
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Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning by Zuhui Pu, Zuhui Pu, Tony Bowei Wang, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Lisha Mou, Lisha Mou

“…IntroductionType 2 diabetes (T2D) is a complex metabolic disorder with significant global health implications. Understanding the molecular mechanisms underlying T2D is crucial for developing effective therapeutic strategies. …”
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Clasificación avanzada de la artrosis de rodilla utilizando tecnologías de Inteligencia Artificial by Facundo Segura, Florencio Pablo Segura, María Paz Lucero Zudaire, Florencio Vicente Segura, Rocío Mendía, Lucía Ribotta Falco, Paula Sofía Zalazar, Daniel Esteban Sequeira

“…Resultados: El modelo alcanzó una precisión global del 92,55% en la clasificación de la artrosis de rodilla, con una sensibilidad del 93,33%. …”
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Enhanced CyGNSS Soil Moisture Retrieval Validated by In-Situ Data in Argentina&#x0027;s Pampas by Javier Arellana, Francisco Grings, Mariano Franco

“…Specifically, with the Cyclone Global Navigation Satellite System (CyGNSS), the reflected signal is often modeled in its simplest form, utilizing the Fresnel reflection coefficients for a semi-infinite dielectric medium corrected with an effective roughness parameter. …”
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Designing a security-oriented leadership model of Mazandaran University of Medical Sciences by Saeid Miladigorji, Mohammad Hassan Shakki, Mojtaba Rezaei Rad

“…Naturally, in such a situation, organizations are looking for frameworks to maintain and improve their competitive advantage and ultimately lead to their continued survival in the global competitive environment. All these factors work hand in hand and will make the organization progress compared to competing organizations. …”
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Research on the multi-agent motivation coupling evolution and synergy improvement for farmland ecological protection in China by Adila Ainiwaerjiang, Xueying Jin, Zhen Xie, Tian Tian, Yuxuan Dang

“…The global ecology movement of the 1960s gave rise to international efforts to of farmland ecological protection. …”
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Evaluating the dual impact of microbial activity and aged refuse layers on landfill leachate clogging: An experimental and LCA perspective by Zhaobin Li, Waifan Tang, Shulun Mak, Siukei Lam, Qingwen Li

“…However, life cycle assessment (LCA) results indicate that while aged refuse layers mitigate clogging, they also increase the global warming potential (GWP) by 10% compared to conventional methods, highlighting the need to balance technical efficacy with environmental sustainability. …”
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25 years of providing evidence on road safety interventions at the city level by Katherine Pérez, Katherine Pérez, Katherine Pérez, Elena Santamariña-Rubio, Maria José López, Maria José López, Maria José López, Maria José López, Lucia Artazcoz, Lucia Artazcoz, Lucia Artazcoz, Lucia Artazcoz, Josep Ferrando, Carlos Pastor, Adnan A. Hyder, Carme Borrell, Carme Borrell, Carme Borrell

“…Road traffic injuries are a significant public health concern, ranking among the leading causes of mortality and disability-adjusted life years lost globally, especially among the young population. Traditionally, road safety has been approached predominantly from a healthcare standpoint, with limited interventions from a comprehensive public health perspective. …”
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Prevalence of Dermatophytosis and Antifungal Activity of Ethanolic Crude Leaf Extract of Tetradenia riparia against Dermatophytes Isolated from Patients Attending Kampala Internati... by Taufik Kakande, Yonah Batunge, Emmanuel Eilu, Ambrose Shabohurira, Justus Abimana, Saheed Adekunle Akinola, Reagan Muhwezi, Abubakar Sunusi Adam, Sarah Kemuma Onkoba, Adamu Almustapha Aliero, Collins Atuheire, Charles Drago Kato, Ibrahim Ntulume

“…Dermatophyte infections are a global health problem but neglected in Uganda. This work aimed at determining prevalence of dermatophytosis and antifungal activity of ethanolic crude leaf extract of Tetradenia riparia against dermatophytes isolated from patients attending Kampala International University Teaching Hospital (KIU-TH), Uganda. …”
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Effectiveness of antimicrobial agent combinations against carbapenem-producing Klebsiella pneumoniae with KPC variants in China by Congcong Liu, Congcong Liu, Yuchen Wu, Yanyan Zhang, Zelin Yan, Danxia Gu, Danxia Gu, Hongwei Zhou, Ning Dong, Chang Cai, Gongxiang Chen, Rong Zhang

“…PurposeCarbapenem-resistant Klebsiella pneumoniae (CRKP) producing carbapenemases poses a global threat to public health. Antimicrobial agent combinations have been promoted as a potential therapeutic strategy for infections. …”
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Patterns of pharmacological treatment in patients with atrial fibrillation: an analysis from the prospective GLORIA-AF Registry Phase III by Bernadette Corica, Giulio Francesco Romiti, Giuseppe Boriani, Brian Olshansky, Tze-Fan Chao, Menno V. Huisman, Marco Proietti, Gregory Y. H. Lip, on behalf of the GLORIA-AF Investigators

“…Methods Based on data from the prospective global GLORIA-AF Registry Phase III (recruiting patients with AF and CHA2DS2-VASc score ≥ 1), we performed a latent class analysis to identify treatment patterns based on 14 drug classes including cardiovascular (CV) and non-CV drugs. …”
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Effect of intermittent theta burst stimulation combined with acoustic startle priming motor training on upper limb motor function and neural plasticity in stroke individuals: study... by Jing Zhang, Yu Chen, Mingzhu Wang, Nan Xia, Jinghong Li, Weiqiang Liang, Yangyang Yin, Linhan Zhai, Qiuxia Wang

“…Introduction Stroke is a major cause of acquired disability globally, yet the neural mechanisms driving motor recovery post-stroke remain elusive. …”
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The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis by Tingting Lin, Tingting Lin, Huimin Wan, Jie Ming, Yifei Liang, Linxin Ran, Jingjing Lu

“…BackgroundSevere Community-Acquired Pneumonia (SCAP) is a serious global health issue with high incidence and mortality rates. …”
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Clinical Study of Limosilactobacillus reuteri for the Treatment of Children with Chronic Tic Disorders/Tourette Syndrome: A Mid-Term Efficacy Evaluation by Yan Liang, Lin Wan, Guanglei Wang, Huimin Yan, Jing Zhang, Xinting Liu, Ziyan Zhang, Gang Zhu, Guang Yang

“…Methods Patients were randomly assigned to receive either Limosilactobacillus reuteri or clonidine transdermal patch treatment for 8 weeks while maintaining their existing treatment. The Yale Global Tic Severity Scale (YGTSS); Swanson, Nolan, and Pelham-IV Scale (SNAP-IV); and Child Behavior Check List (CBCL) scores were assessed before and after treatment. …”
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Discovery of anti-Ebola virus multi-target inhibitors from traditional Chinese medicine database using molecular screening, biophysical investigation, and binding free energy calcu... by Abbas Khan, Abrar Mohammad Sayaf, Anwar Mohammad, Fahad M. Alshabrmi, Tarek Benameur, Dong-Qing Wei, Kar Kheng Yeoh, Abdelali Agouni

“…The lack of effective treatment or vaccine for this pathogen poses a serious threat to a global pandemic. Therefore, it is imperative to explore new drugs and therapies to combat this life-threatening infection. …”
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