Clinical characteristics and associated factors of pediatric acute necrotizing encephalopathy: a retrospective study by Huiling Zhang, Yilong Wang, Qianyun Ding, Xuekun Li, Sheng Ye

“…The fatal group displayed lower Glasgow Coma Scale (GCS) scores and severe complications. …”
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An analysis of referral patterns of traumatic brain injury at Groote Schuur Hospital Trauma Centre by N Parker, T Navsaria, M Lopez, L Marineau, R Maine, K Chu, T Govender, D McPherson, P Navsaria

“…Demographic data (age, sex), mechanism of injury and Glasgow Coma Score were recorded. Referral pathways were determined, and final disposition of patients was recorded. …”
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Factores de riesgo para la neumonía asociada al ictus isquémico agudo by Alexis Suárez Quesada, Alexis Álvarez Aliaga, Andrés Quesada Vázquez

“…Se identificaron los siguientes factores de riesgo: historia de enfermedad pulmonar obstructiva crónica (OR: 9,74; IC 95 % 2,047-46,410), disfagia (OR: 7,822; IC 95 % 2,525-24,236), puntuación de Glasgow ≤ 11 puntos (OR: 4,699; IC 95 % 1,917-11,520) y disartria/afasia motora severa (OR: 4,432; IC 95 % 1,562- 12,576).…”
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Natremia Significantly Influences the Clinical Outcomes in Patients with Severe Traumatic Brain Injury by Bharti Sharma, Winston Jiang, Munirah M. Hasan, George Agriantonis, Navin D. Bhatia, Zahra Shafaee, Kate Twelker, Jennifer Whittington

“…We found statistically significant differences in SLs at H admission, ICU admission, and ICU discharge when compared to the Injury Severity Score (ISS) and the Glasgow Coma Scale (GCS) at admission. A linear regression analysis revealed a statistically significant positive correlation between ICU admission SLs and ISS. …”
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Outcomes and physiologic responses associated with ketamine administration after traumatic brain injury in the United States and Canada: a retrospective analysis by Austin J. Peters, Saad A. Khan, Seiji Koike, Susan Rowell, Martin Schreiber

“…Ketamine-exposed subjects were younger (37.3±16.9 years vs. 42.0±18.6 years, P=0.037), had a worse initial Glasgow Coma Scale score (7±3 vs. 8±4, P=0.003), and were more likely to be intubated than ketamine-unexposed subjects (88.5% vs. 44.2%, P<0.001). …”
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SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocolsResearch in context by Moreno Ursino, Guillermo Villacampa, Jan Rekowski, Munyaradzi Dimairo, Olga Solovyeva, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Thomas R. Jeffry Evans, Elizabeth Garrett-Mayer, Robert M. Golub, Christina Guo, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Adrian Mander, Lynley V. Marshall, James Matcham, Dhrusti Patel, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Mahtab Rouhifard, Lesley Seymour, Yoshiya Tanaka, Christopher J. Weir, Johann de Bono, Christina Yap

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CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

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Diabetic ketoacidosis treatment outcomes and its associated factors among adult patients with diabetes mellitus admitted to public hospitals in Nekemte Town, Ethiopia: a cross-sect... by Daniel Mitiku Yigazu, Matiyos Lema, Firomsa Bekele, Dawit Tesfaye Daka, Dagim Samuel, Nigatu Addisu

“…Independent predictors of DKA recovery were comorbidities [AOR: 3.45, 95% CI: 1.33, 9.72], admission Glasgow Coma Scale (GCS) score (&lt;8) [AOR: 2.74, 95% CI: 1.02, 7.34], random blood glucose (RBS) (≥ 500) [AOR: 3.07 (95% CI: 1.12, 8.39)], and urine ketones (≥ +3) [AOR: 3.24, 95% CI: 1.18, 8.88].Conclusion and recommendationMost of the treated patients with DKA were discharged with improvement. …”
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Proximal Policy Optimization for Crowd Evacuation in Complex Environments&#x2014;A Metaverse Approach at Krung Thep Aphiwat Central Terminal, Thailand by Sushank Chaudhary, Nitinun Sinpan, Pruk Sasithong, Sunita Khichar, Panithan la-Aiddee, Natt Leelawat, Amir Parnianifard, Suvit Poomrittigul, Lunchakorn Wuttisittikulkij

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Improved Outcomes following the Establishment of a Neurocritical Care Unit in Saudi Arabia by Ibrahim Soliman, Waleed Tharwat Aletreby, Fahad Faqihi, Nasir Nasim Mahmood, Omar E. Ramadan, Ahmad Fouad Mady, Babar Kahlon, Abdulrahman Alharthy, Peter Brindley, Dimitrios Karakitsos

“…Secondary outcomes were ICU length of stay (LOS), predictors of ICU and hospital discharge, ICU discharge Glasgow Coma Scale (GCS), frequency of tracheostomies, ICP monitoring, and operative interventions. …”
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Livogrit mitigates ANIT-induced cholestasis-like symptoms in an in vivo model by curbing hepatic inflammation and regulating BAX, TGF-β, MMP-9 and α-SMA gene expression by Acharya Balkrishna, Ritu Paliwal, Surjeet Singh, Rani Singh, Vivek Gohel, Rishabh Dev, Kunal Bhattacharya, Sandeep Sinha, Anurag Varshney

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Geriatric Trauma Outcome Score for Predicting Mortality among Older Korean Adults with Trauma: Is It Applicable in All Cases? by Jonghee Han, Su Young Yoon, Junepill Seok, Jin Young Lee, Jin Suk Lee, Jin Bong Ye, Younghoon Sul, Se Heon Kim, Hong Rye Kim

“…The areas under the curves (AUCs) of 1–TRISS and GTOS for the total population were 0.763 (95% confidence interval [CI], 0.719–0.806) and 0.794 (95% CI, 0.755–0.833), respectively. In the Glasgow Coma Scale (GCS) ≤12 group, the in-hospital mortality rate was 27.5% (79 deaths). …”
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Development of a core outcome set for school-based intervention studies on preventing childhood overweight and obesity: study protocol by Mai Chinapaw, Teatske M Altenburg, Tessa J Roseboom, Jo Salmon, Deirdre Harrington, Lotte W de Vries, Iris Grooten, Janneke Van 't Hooft, Arend van Deutekom

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A critical review on enhancement and sustainability of energy systems: perspectives on thermo-economic and thermo-environmental analysis by Sunday O. Oyedepo, Mufutau A. Waheed, Fidelis I. Abam, Joseph O. Dirisu, Olusegun D. Samuel, Olusegun D. Samuel, Oluseyi O. Ajayi, Tosin Somorin, Abimbola P. I. Popoola, Oluwaseun Kilanko, Philip O. Babalola

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Fractionation of Rare Earth Elements in Greisen and Hydrothermal Veins Related to A-Type Magmatism by Mikael Tillberg, Olga M. Maskenskaya, Henrik Drake, Johan K. Hogmalm, Curt Broman, Anthony E. Fallick, Mats E. Åström

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Risperidone versus placebo for aggression following traumatic brain injury: a feasibility randomised controlled trial by Paul Bassett, Tim Weaver, Shoumitro Deb, Mike Crawford, David Sharp, Lina Aimola, Verity Leeson, Mayur Bodani, Lucia Li

“…Follow-up participants at 12 weeks using a battery of assessment scales to measure changes in aggressive behaviour and irritability (Modified Overt Aggression Scale (MOAS)-primary outcome, Irritability Questionnaire) as well as global functioning (Glasgow Outcome Scale-Extended, Clinical Global impression) and quality of life (EQ-5D-5L, SF-12), mental health (Hospital Anxiety and Depression Scale) and medication adverse effects (Udvalg for Kliniske Undersøgelser).Results Six participants were randomised to the active arm of the trial and eight to the placebo arm over a 10-month period (28% of our target). …”
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Women and birth partners’ experiences of cervical ripening at home and in hospital by Cassandra Yuill, Mairi Harkness, Helen Cheyne, Boo Charkin, Monica Ferreira, Eloise Price, Amarnath Bhide, Mairead Black, Kathleen Boyd, Neelam Heera-Shergill, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Sarah J. Stock, Rosemary Townsend, Linda J. Williams, Christine McCourt

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Predicting 30-day mortality in severely injured elderly patients with trauma in Korea using machine learning algorithms: a retrospective study by Jonghee Han, Su Young Yoon, Junepill Seok, Jin Young Lee, Jin Suk Lee, Jin Bong Ye, Younghoon Sul, Se Heon Kim, Hong Rye Kim

“…Analysis of important features of XGBoost using SHAP revealed associations such as a high Glasgow Coma Scale negatively impacting mortality probability, while higher counts of transfused red blood cells were positively correlated with mortality probability. …”
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The Prognostic Value of CRP/Alb Ratio in Predicting Overall Survival for Hepatocellular Carcinoma Treated with Transcatheter Intra-Arterial Therapy Combined with Molecular-Targeted... by Huang X, Peng G, Kong Y, Cao X, Zhou X

“…The discriminatory capability of inflammation-based prognostic scores—including the CRP/Alb ratio, C-reactive protein and alpha-fetoprotein in immunotherapy (CRAFITY) score, modified Glasgow prognostic score (mGPS), platelet-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII)—was assessed using the area under the curve (AUC).Results: A total of 133 patients met the inclusion criteria. …”
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A surveillance study to determine the accuracy of mild traumatic brain injury diagnosis in an emergency department: protocol for a retrospective cohort study by Ian D Cameron, Ilaria Pozzato, Ashley Craig, Bamini Gopinath, Mark Gillett, Annette Kifley, Kim Van Vu, Susanne Meares, Anthony Liang

“…The WHO operational criteria for the clinical identification of mTBI cases is the presence of: (1) a Glasgow Coma Scale (GCS) of 13–15 after 30 min postinjury or on presentation to hospital; (2) one or more of the following: post-traumatic amnesia (PTA) of less than 24 hours’ duration, confusion or disorientation, a witnessed loss of consciousness for ≤30 min and/or a positive CT brain scan. …”
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