Identification of Potential Diagnostic Biomarkers of Carotid Atherosclerosis in Obese Populations by Wu X, Pan J, Pan X, Kang J, Ren J, Huang Y, Gong L, Li Y

“…Xize Wu,1,* Jiaxiang Pan,2,* Xue Pan,1,3,* Jian Kang,1 Jiaqi Ren,1 Yuxi Huang,1 Lihong Gong,2,4 Yue Li2,4 1Graduate School, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, 110847, People’s Republic of China; 2Department of Cardiology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, 110032, People’s Republic of China; 3College of Traditional Chinese Medicine, Dazhou Vocational College of Chinese Medicine, Dazhou, Sichuan, 635000, People’s Republic of China; 4Liaoning Provincial Key Laboratory of TCM Geriatric Cardio-Cerebrovascular Diseases, Shenyang, Liaoning, 110032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lihong Gong; Yue Li, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33, Beiling Street, Huanggu District, Shenyang, Liaoning, 110032, People’s Republic of China, Tel +86 024-82961105, Email Linda1795@sina.com; med_liyue@163.comObjective: This study aimed to investigate the potential mechanisms and biomarkers between Obesity (OB) and carotid atherosclerosis (CAS).Methods: The GSE12828, GSE125771, GSE43292, and GSE100927 datasets were combined and normalized to obtain CAS-related differentially expressed genes (DEGs), and OB-related DEGs were obtained from the GSE151839 dataset and the GeneCards database. …”
Get full text

Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer’s disease in humans by Bryan J. Neth, Kevin Huynh, Corey Giles, Tingting Wang, Natalie A. Mellett, Thy Duong, Colette Blach, Leyla Schimmel, Thomas C. Register, Kaj Blennow, Henrik Zetterberg, Richa Batra, Annalise Schweickart, Amanda Hazel Dilmore, Cameron Martino, Matthias Arnold, Jan Krumsiek, Xianlin Han, Pieter C. Dorrestein, Rob Knight, Peter J. Meikle, Suzanne Craft, Rima Kaddurah-Daouk

Get full text

Plasma myeloperoxidase interactions with cadmium, lead, arsenic, and selenium and their impact on chronic kidney disease by Hsi-Hsien Chen, Ya-Li Huang, Chih-Yin Wu, Mei-Chieh Chen, Horng-Sheng Shiue, Sheng-Lun Hsu, Ying-Chin Lin, Yu-Mei Hsueh

Get full text

Association analysis of suicide risk assessed with Mini International Neuropsychiatric Interviews’ Suicidality Module in adolescents with non suicidal self injury disorder by Shuo Geng, Shuo Geng, Wen Zhang, Xiang Gao, Lele Qu, Xueping Zheng, Jian Sun, Mingdong Xu, Hua Lin, Xueyu Jia, Xu Zhang

Get full text

An early lung cancer diagnosis model for non-smokers incorporating ct imaging analysis and circulating genetically abnormal cells (CACs) by Ran Ni, Yongjie Huang, Lei Wang, Hongjie Chen, Guorui Zhang, Yali Yu, Yinglan Kuang, Yuyan Tang, Xing Lu, Hong Liu

Get full text

High BMP7 Expression May Worsen Airway Disease in COPD by Altering Epithelial Cell Behavior by Dong W, Xie M, Ming C, Li H, Xu X, Cui L, Wang W, Li Y

“…Wenyan Dong,1,* Mengshuang Xie,2,* Chunjie Ming,3 Haijun Li,2 Xia Xu,2 Liwei Cui,4 Wei Wang,5 Yi Li6 1Department of General Practice, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 2Department of Geriatric Medicine, Laboratory of Gerontology and Anti-aging Research, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 3National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 4Department of Pulmonary and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 5Medical Integration and Practice Center, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 6Department of Obstetrics and Gynecology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Wang; Yi Li, Email styw28@163.com; 202062009073@email.sdu.edu.cnPurpose: Airway disease is the main pathological basis of chronic obstructive pulmonary disease (COPD), but the underlying mechanisms are unknown. …”
Get full text

Delirium Management Quality Improvement Project to Improve Awareness and Screening in a Medical ICU by Hirsh Makhija, Kyle Digrande, Omar Awan, Russell G. Buhr, Rajan Saggar, Victoria Ramirez, Rainbow Tarumoto, Janelle M. Fine, Atul Malhotra, Dale M. Needham, Jennifer L. Martin, Biren B. Kamdar

Get full text

Efficacy, safety, and biomarker analysis of TACE combined with lenvatinib plus sintilimab in unresectable hepatocellular carcinoma: a real-world study by Lingzhan Meng, Hu Li, Yingjie Ji, Peng Yu, Zizheng Wang, Li Cao, Bin Shi, Yanling Shao, Jin Yan, Yinjie Gao, Zhenyu Zhu

Get full text

Inhibition of MEK1 Signaling Pathway in the Liver Ameliorates Insulin Resistance by Atsunori Ueyama, Nobuhiro Ban, Masanori Fukazawa, Tohru Hirayama, Minako Takeda, Tatsuo Yata, Hiroyasu Muramatsu, Masaki Hoshino, Marii Yamamoto, Masao Matsuo, Yuka Kawashima, Tatsuhiko Iwase, Takehisa Kitazawa, Youichi Kushima, Yuichiro Yamada, Yoshiki Kawabe

Get full text

Genomic insights into the alphaproteobacterium Georhizobium sp. MAB10 revealed a pathway of Mn(II) oxidation-coupled anoxygenic photoautotrophy: a novel understanding of the biotic... by Xiuli Xu, Litao Zhang, Fuhang Song, Guoliang Zhang, Linlin Ma, Na Yang

Get full text

Similar Survival Between Non-Western Immigrant Patients and Danish-Born Patients with Lymphoma: A Danish Population-Based Study by Simonsen MR, Maksten EF, Jakobsen LH, Severinsen MT, Dann EJ, Frederiksen H, Niemann CU, Jørgensen JM, Clausen MR, Starklint J, Johnsen SP, El-Galaly TC, Baech J

“…Mikkel Runason Simonsen,1,2 Eva Futtrup Maksten,1,3 Lasse Hjort Jakobsen,1 Marianne Tang Severinsen,1,3 Eldad J Dann,4 Henrik Frederiksen,5,6 Carsten Utoft Niemann,7 Judit Mészáros Jørgensen,8 Michael Roost Clausen,9 Jørn Starklint,10 Søren Paaske Johnsen,11 Tarec Christoffer El-Galaly,1,3,5,12 Joachim Baech1,13 1Department of Hematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark; 2Department of Mathematical Sciences, Aalborg University, Aalborg, Denmark; 3Department of Clinical Medicine, Aalborg University, Aalborg, Denmark; 4Department of Haematology, Rambam Medical Center, and Bruce Rappaport Faculty of Medicine, Technion -Israel Institute of Technology, Haifa, Israel; 5Department of Hematology, Odense University Hospital, Odense, Denmark; 6Academy of Geriatric Cancer Research (Agecare), Odense University Hospital, Odense, Denmark; 7Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; 8Department of Hematology, Aarhus University Hospital, Aarhus, Denmark; 9Department of Hematology, Vejle Hospital, Vejle, Denmark; 10Department of Medicine: Hematology, Goedstrup Hospital, Goedstrup, Denmark; 11Danish Center for Health Services Research, Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark; 12Department of Medicine Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden; 13Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, DenmarkCorrespondence: Mikkel Runason Simonsen, Email Mikkel.simonsen@rn.dkPurpose: This nationwide Danish cohort study compared overall survival (OS) between non-Western immigrant patients and Danish-born patients with lymphoma in Denmark. …”
Get full text

Effectiveness of antimicrobial agent combinations against carbapenem-producing Klebsiella pneumoniae with KPC variants in China by Congcong Liu, Congcong Liu, Yuchen Wu, Yanyan Zhang, Zelin Yan, Danxia Gu, Danxia Gu, Hongwei Zhou, Ning Dong, Chang Cai, Gongxiang Chen, Rong Zhang

Get full text

Prevalence of cataracts in Iran based on the Persian eye cohort study by Fateme Alipour, Parisa Abdi, Hassan Asadigandomani, Mehran Rezakhani, Fatemeh Moosaie, Fateme Jafari, Mehdi Yaseri, Nazgol Motamed-Gorji, Fahimeh Khalili, Roya Tavakoli, Abolfazl Tahkor, Masoome Mohseni, Samira Salimpour, Seyed Mohammad Javad Mousavi Aref, Mohammad Mirzaei, Mohammadreza Soleimani, Kourosh Shahraki, Yousef Alizade, Mohammad Reza Shoja, Gholam Reza Khataminia, Mahmoud Jabbarvand Behrouz, Hassan Hashemi

Get full text

A mixed-methods observational study of strategies for success in implementation science: overcoming emergency departments hurdles by Deonni P. Stolldorf, Alan B. Storrow, Dandan Liu, Cathy A. Jenkins, Rachel A. Hilton, Karen F. Miller, Joy Kim, Deepika Boopathy, Satheesh Gunaga, Bory Kea, Joseph Miller, Sean P. Collins

Get full text

Multimodal Imaging of Patients With Gliomas Confirms C-MET PET as a Complementary Marker to MRI for Noninvasive Tumor Grading and Intraindividual Follow-Up After Therapy by Kai R. Laukamp MD, Florian Lindemann PhD, Matthias Weckesser MD, Volker Hesselmann MD, Sandra Ligges PhD, Johannes Wölfer MD, Astrid Jeibmann MD, Bastian Zinnhardt PhD, Thomas Viel PhD, Michael Schäfers MD, Werner Paulus MD, Walter Stummer MD, Otmar Schober PhD, MD, Andreas H. Jacobs MD

Get full text

Metabolic and functional factors associated with a change in resting metabolic rate among older adults with type 2 diabetes– results from the CEV-65 randomized trial by Assaf Buch, Roy Eldor, Ofer Kis, Arie Ben-Yehuda, Gizell Green, Yona Greenman, Sharon Barak

Get full text

Macrophage-related inflammatory responses to degradation products of biodegradable molybdenum implants by Danyang Liu, Jiahao Chen, Jiannan Zhou, Jingtao Dai, Haotian Qin, Guojiang Wan, Junyu Qian, Ping Li, Jiang Li

Get full text

Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled... by Eva Skovlund, Rune Haaverstad, Henrik Zetterberg, Jorunn L Helbostad, Rolf Busund, Johan Raeder, Theis Tønnessen, Torgeir Bruun Wyller, Melanie R Simpson, Nils Kristian Skjærvold, Bjørn Erik Neerland, Svein Aslak Landsverk, Ieva Martinaityte, Hilde Margrethe Norum, Geir Selbaek, Elisabeth Skaar, Arjen JC Slooter, Øyvind Sverre Svendsen, Alexander Wahba

Get full text

Peptide-based vaccine targeting IL17A attenuates experimental spondyloarthritis in HLA-B27 transgenic rats by Tetsuya Tomita, Hiromi Rakugi, Hiroki Hayashi, Ryuichi Morishita, Jiao Sun, Yuka Yanagida, Shota Yoshida, Satoshi Baba, Akiko Tenma, Masayoshi Toyoura, Sotaro Kawabata, Takako Ehara, Ryoko Asaki, Makoto Sakaguchi, Hideki Tomioka, Munehisa Shimamura, Hironori Nakagami

Get full text

Addressing Critical Mistakes in Administering Intravenous Medications at Omdurman Military Hospital, Khartoum, Sudan by Ahmed WAM, Abdelrahman AEHE, Mohamed AA, Mohammed IO, Mustafa AMA, Ahmed ZEE, Mohamed MMT, Alghamdi FAA, Elbashir AEE, Alkubati S, Al-Sowaidi A, Dinar NMAA, Obadi AA, Saleh KA

“…Waled AM Ahmed,1,2 Amna Eltom Hajo Elsheikh Abdelrahman,3 Amal Abdelgadir Mohamed,4 Ibrahim Osman Mohammed,5 Amna Mohammed Ali Mustafa,6 Zeinab Eltayeb Elfaki Ahmed,7 Maab Mutaz Tagelsir Mohamed,8 Fahad Abdullah A Alghamdi,9 Amira EE Elbashir,10 Sameer Alkubati,11 Akram Al-Sowaidi,12 Neimat MAA Dinar,13 Abdalkhaliq Ahmed Obadi,1 Khalil A Saleh14 1Community Medicine Department, Faculty of Medicine, Al-Saeeda University, Sanaa, Yemen; 2Community Health Nursing Department, Faculty of Nursing, Al-Baha University, Al-Baha, Saudi Arabia; 3Clinical Pharmacy Department, Faculty of Pharmacy, Omdurman Islamic University, Khartoum, Sudan; 4Department of Maternity and Childhood Nursing, College of Nursing, Taif University, Taif, Saudi Arabia; 5Clinical Pharmacy Department, Faculty of Pharmacy, Gazeira University, Gazeira, Sudan; 6Department of Nursing, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia; 7Obstetrics and Gynecology Department, Faculty of Medicine, Alzaeim Alazhari University, Khartoum, Sudan; 8Clinical Pharmacy Department, Faculty of Pharmacy, University of Medical Sciences and Technology, Khartoum, Sudan; 9Geriatric Care Nursing Department, Faculty of Nursing, Al-Baha University, Al-Baha, Saudi Arabia; 10Maternal and Child Health Nursing Department, Faculty of Nursing, Al-Baha University, Al-Baha, Saudi Arabia; 11Department of Medical Surgical Nursing, College of Nursing, University of Ha’il, Hail City, Saudi Arabia, and Department of Nursing, Faculty of Medicine and Health Sciences, Hodeida University, Hodeida, Yemen; 12Pharmacy Department, Faculty of Medical Sciences, Al Janad University for Science & Technology, Taiz, Yemen; 13Medical-Surgical Nursing Department, Faculty of Nursing, Al-Baha University, Al-Baha, Saudi Arabia; 14Department of Medical Surgical, College of Nursing, University of Ha’il, Hail, Saudi ArabiaCorrespondence: Waled AM Ahmed, Community Medicine Department, Faculty of Medicine, Al-Saeeda University, Sanaa, Yemen. …”
Get full text