Genetic code expansion reveals site-specific lactylation in living cells reshapes protein functions by Chang Shao, Shuo Tang, Siqin Yu, Chenguang Liu, Yueyang Zhang, Tianyan Wan, Zimeng He, Qi Yuan, Shihan Wu, Hanqing Zhang, Ning Wan, Mengru Zhan, Ren Xiang Tan, Haiping Hao, Hui Ye, Nanxi Wang

“…To advance the exploration of its biological functions, here we develop a comprehensive workflow that integrates proteomics to identify lactylated sites, genetic code expansion (GCE) for the expression of site-specifically lactylated proteins in living cells, and an integrated functional analysis (IFA) platform to evaluate their biological effects. …”
Get full text

The Genetic Diversity and Geographic Differentiation of the Wild Soybean in Northeast China Based on Nuclear Microsatellite Variation by Hongkun Zhao, Yumin Wang, Fu Xing, Xiaodong Liu, Cuiping Yuan, Guangxun Qi, Jixun Guo, Yingshan Dong

“…AMOVA analysis showed that the genetic differentiation among latitude and longitude populations was 0.088 and 0.058, respectively, and the majority of genetic variation occurred within populations. …”
Get full text

Estimation of crossbreeding and genetic parameters for reproductive traits of Boer x Central Highland goats in Ethiopia. by Zeleke Tesema, Belay Deribe, Mekonnen Tilahun, Alemu Kefale, Getachew Worku Alebachew, Kefyalew Alemayehu, Tesfaye Getachew, Damitie Kebede, Mengistie Taye, Solomon Gizaw

“…Additive genetic and non-additive parameters for reproductive traits of Boer x Central Highland goats were estimated. …”
Get full text

BREEDING AND GENETIC ESTIMATION OF SPRING BREAD WHEAT POPULATIONS OF THE SIBERIAN SHUTTLE BREEDING NURSERY OF CIMMYT by V. P. Shamanin, A. I. Morgunov, J. Manes, Y. I. Zelensky, A. S. Chursin, M. A. Levshunov, I. V. Pototskaya, I. E. Likhenko, T. A. Manko, I. I. Karakoz, A. V. Tabachenko, S. L. Petukhovsky

Get full text

Optimization of Wind Turbine Airfoil Using Nondominated Sorting Genetic Algorithm and Pareto Optimal Front by Ziaul Huque, Ghizlane Zemmouri, Donald Harby, Raghava Kommalapati

“…Elitist Non-dominated Sorting Genetic Algorithm (NSGA-II) was used to determine the Pareto optimal set based on the response surfaces. …”
Get full text

Clinical and biochemical features of atherogenic hyperlipidemias with different genetic basis: A comprehensive comparative study. by Anastasia V Blokhina, Alexandra I Ershova, Anna V Kiseleva, Evgeniia A Sotnikova, Anastasia A Zharikova, Marija Zaicenoka, Yuri V Vyatkin, Vasily E Ramensky, Vladimir A Kutsenko, Olga A Litinskaya, Maria S Pokrovskaya, Svetlana A Shalnova, Alexey N Meshkov, Oxana M Drapkina

“…Patients with genetically-based hyperlipidemias exhibit a wide phenotypic variability. …”
Get full text

Identification of Taihang-chicken-specific genetic markers using genome-wide SNPs and machine learning by Fu Wei, Zhang Ran, Ding Hong, Wang Wenjun, Liu Huage, Zang Sumin, Zhou Rongyan

“…Taihang is an indigenous breed in Hebei Province and has a long history of evolution. To uncover the genetic basis and protect the genetic resources, it is important to develop accurate markers to identify Taihang at the molecular level. …”
Get full text

Analysis of strawberry genetic collection (Fragaria L.) for Rca2 and Rpfl genes with molecular markers by I. V. Luk’yanchuk, A. S. Lyzhin, I. I. Kozlova

“…To assess allelic state Rca2 anthracnose resistance gene the dominant SCAR marker STS-Rca2_240 was used, was linked to the resistance gene Rca2 with a genetic distance of 2.8 cM. Rpf1 gene red stele root rot resistance was identified with the dominant SCAR marker R1A, was linked to the resistance gene Rpf1 with a genetic distance of 3.0 cM. …”
Get full text

Harnessing Genetic Resistance in Maize and Integrated Rust Management Strategies to Combat Southern Corn Rust by Jiaying Chang, Shizhi Wei, Yueyang Liu, Zhiquan Zhao, Jie Shi

“…<i>P. polysora</i> is an obligate biotrophic fungal pathogen that cannot be cultured in vitro or genetically modified, thus complicating the study of the molecular bases of its pathogenicity. …”
Get full text

Epidemiological and genetic charateristics of Vibrio vulnificus from diverse sources in China during 2012–2023 by Dongling Long, Min Li, Lingchao Ma, Jiewen Huang, Chao Lv, Yiwen Chen, Zile Cheng, Chang Liu, Huitao Huang, Xiaokui Guo, Chao Yang, Yongzhang Zhu

“…The lack of a national annual surveillance program in China has hindered understanding of its epidemiological characteristics and genetic diversity. This study characterized 150 V. vulnificus isolates collected from diverse sources in China during 2012–2023, including seafood, aquaculture water, migratory birds, marine animals, and clinical patients. …”
Get full text

Canine Cutaneous Leishmaniasis: Dissemination and Tissue Tropism of Genetically Distinct Leishmania (Viannia) braziliensis Populations by Guilherme Marx de Oliveira, Maria de Fátima Madeira, Fernanda Santos Oliveira, Marize Quinhones Pires, Raquel da Silva Pacheco

“…In contrast, populations that showed spreading to internal organs displayed a more polymorphic genetic profile. Despite the heterogeneity, L. (V.) braziliensis populations with identical genetic profiles were observed in popliteal and cervical lymph nodes of the same animal. …”
Get full text

Analysis of Marketing Prediction Model Based on Genetic Neural Network: Taking Clothing Marketing as an Example by Hua Peng, Luxiao Dong, Yi Sun, Yanfang Jiang

“…With the development of genetic neural network technology, this technology has been more and more widely used in signal processing, pattern recognition and other application fields. …”
Get full text

Genomic patterns of strain-specific genetic structure, linkage, and selection across fall armyworm populations by Ashley E. Tessnow, Rodney N. Nagoshi, Robert L. Meagher, Todd M. Gilligan, Ben M. Sadd, Yves Carrière, Holly N. Davis, Shelby J. Fleischer, Kelly Richers, John C. Palumbo, Patrick Porter, Jose Carlos Verle Rodrigues, Gregory A. Sword

“…Abstract Background Molecular genetic approaches have become vital to understanding the evolutionary processes that act on insect pest populations. …”
Get full text

Inverse Analysis of the Partitioning Deformation Modulusof High-Arch Dams Based on Quantum Genetic Algorithm by Yantao Zhu, Xinqiang Niu, Jimin Wang, Chongshi Gu, Erfeng Zhao, Lixian Huang

“…A mechanical parameter inversion of high-arch dams is built from the intelligent optimization of an established algorithm by applying the quantum genetic algorithm. The proposed algorithm is tested to be feasible and valid for practical engineering projects and therefore shows scientific and practical application values.…”
Get full text

Response to the SAMHSA Clinical Advisory: Considerations for Genetic Testing in the Assessment of Substance Use Disorder Risk by Green RP, Blum K, Lewandrowski KU, Gold MS, Lewandrowski AP, Thanos PK, Dennen CA, Baron D, Elman I, Sharafshah A, Modestino EJ, Badgaiyan RD

Subjects: Get full text

Prenatal genetic detection in foetus with gallbladder size anomalies: cohort study and systematic review of the literature by Yimo Zeng, Rong Hu, Jian Lu, Yiming Qi, Dan Chen, Chaoxiang Yang, Jing Wu

“…The overall diagnostic yield of genetic tests was 10.57% (24/227). Aneuploidies were identified in seven foetuses. …”
Get full text

Screw Performance Degradation Assessment Based on Quantum Genetic Algorithm and Dynamic Fuzzy Neural Network by Xiaochen Zhang, Hongli Gao, Haifeng Huang

“…To evaluate the performance of ball screw, screw performance degradation assessment technology based on quantum genetic algorithm (QGA) and dynamic fuzzy neural network (DFNN) is studied. …”
Get full text

Stability of Uncertain Impulsive Stochastic Genetic Regulatory Networks with Time-Varying Delay in the Leakage Term by Jun Li, Manfeng Hu, Jinde Cao, Yongqing Yang, Yinghua Jin

“…This paper is concerned with the stability problem for a class of uncertain impulsive stochastic genetic regulatory networks (UISGRNs) with time-varying delays both in the leakage term and in the regulator function. …”
Get full text

Low-density SNP marker sets for genetic variation analysis and variety identification in cultivated citrus by Phuong Linh Nguyen, Jin-Kee Jung, Jee-Soo Park, Sung-Chur Sim

“…Abstract Background The Citrus species are major fruit crops cultivated in the world and have complex genetic relationships due to sexual comparability between Citrus and related genera. …”
Get full text

Genetic Background and Phenotypic Aspects of Light-Induced Carotenoid Biosynthesis in <i>Isosphaeraceae</i> Planctomycetes by Anastasia A. Ivanova, Igor Y. Oshkin, Aleksandr A. Ashikhmin, Olga V. Danilova, Svetlana N. Dedysh

“…We examined the carotenogenesis and its genetic background in a novel planctomycete of the family <i>Isosphaeraceae</i>, <i>Singulisphaera</i> sp. …”
Get full text