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11381
Expression Profile of Brain Aging and Metabolic Function are Altered by Resveratrol or α-Ketoglutarate Supplementation in Rats Fed a High-Fat Diet
Published 2021-07-01“…HFD feeding induces metabolic dysfunction and age-related genetic alterations in the hypothalamus of middle-aged rats, while dietary RESV or AKG may partially retard these effects, even though these compounds act in a different and specific manner.…”
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11382
Comprehensive analysis of the mechanisms conferring resistance to phenamacril in the Fusarium species
Published 2025-02-01“…We examine the molecular, genetic, and environmental factors contributing to this resistance. …”
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11383
Prevalence and dynamics of antimicrobial resistance in pioneer and developing Arctic soils
Published 2025-01-01“…Specifically, we assess how the magnitude and spread of AMR changes with soil development stages, including antibiotic resistance genes (ARGs), mobile genetic elements (MGEs), and antibiotic-resistant bacteria (ARB). …”
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11384
A Brief Epidemiologic Review of Psoriasis
Published 2024-12-01“…Psoriasis is an intricate, long-lasting, immune-mediated inflammatory skin condition that has a genetic origin. The body is affected to varying degrees; it can affect almost the entire body or just a few isolated red, scaly plaques. …”
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11385
What does external morphometry tell us about stock discrimination of Sardina pilchardus stocks from Türkiye?
Published 2024-09-01“…In addition, we would like to conclude that the morphological difference is not at the genetic level, and would like to emphasize the need for additional stock discrimination methods.…”
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11386
The Composition of Gut Microbiota in Patients Bearing Hashimoto’s Thyroiditis with Euthyroidism and Hypothyroidism
Published 2020-01-01“…Hashimoto’s thyroiditis (HT), a type of autoimmune disease, occurs due to genetic predisposition and environmental factors. …”
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11387
Systematically developing a registry of splice-site creating variants utilizing massive publicly available transcriptome sequence data
Published 2025-01-01“…Abstract Genomic variants causing abnormal splicing play important roles in genetic disorders and cancer development. Among them, variants that cause the formation of novel splice-sites (splice-site creating variants, SSCVs) are particularly difficult to identify and often overlooked in genomic studies. …”
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11388
Sound Radiation Analysis of a Front Side Window Glass of DrivAer Model under Wind Excitation
Published 2018-01-01“…Then, a platform based on Matlab-Abaqus cosimulation was originally developed, and the genetic algorithm was applied to find out the best fitted spring stiffness, which was used to build the equivalent model. …”
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11389
Combined Klippel-Feil syndrome, Sprengel deformity, and diffuse large B-cell lymphoma: A rare case report
Published 2025-03-01“…Klippel-Feil syndrome (KFS) is a rare congenital disorder characterized by the fusion of cervical vertebrae, with a clinical presentation that can vary widely due to genetic and phenotypic diversity. While KFS can occur as an isolated anomaly, it is often associated with other congenital conditions, such as Sprengel deformity, which may present with or without an omovertebral bone, complicating diagnosis and management. …”
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11390
Enhancing prediction of wildfire occurrence and behavior in Alaska using spatio-temporal clustering and ensemble machine learning
Published 2025-03-01“…First, NASA’s Fire Information for Resource Management System (FIRMS) dataset spanning +20 years is processed using a spatio-temporal clustering algorithm to create refined wildfire datasets. A sequential Genetic Algorithm (GA) is employed for cost-effective feature selection from 49 geospatial features, including remote sensing and reanalysis data. …”
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11391
AI-driven automated discovery tools reveal diverse behavioral competencies of biological networks
Published 2025-01-01“…Many applications in biomedicine and synthetic bioengineering rely on understanding, mapping, predicting, and controlling the complex behavior of chemical and genetic networks. The emerging field of diverse intelligence investigates the problem-solving capacities of unconventional agents. …”
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11392
Comparative study of some species of the genus Acer L. in the Hirkan flora using dendrochronological methods
Published 2025-01-01“…Among them, climatic conditions, habitat features, as well as genetic and age characteristics of plants play a particularly important role.…”
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11393
PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice
Published 2015-01-01“…This confirmed the absolute requirement for PPARδ in the physiological actions of GW501516 and confirmed the potential utility against the human form of this receptor. Surprisingly the genetic deletion of PPARα also abrogated the effect of GW501516 in terms of both weight loss and hepatic lipid accumulation. …”
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11394
Spatial stochastic models of cancer: Fitness, migration, invasion
Published 2013-03-01“…Cancer progression is driven by genetic and epigenetic events giving rise to heterogeneity of cellphenotypes, and by selection forces that shape the changingcomposition of tumors. …”
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11395
Bleomycin-Treated Chimeric Thy1-Deficient Mice with Thy1-Deficient Myofibroblasts and Thy-Positive Lymphocytes Resolve Inflammation without Affecting the Fibrotic Response
Published 2015-01-01“…We aimed to identify genetic changes in lung myofibroblasts following Thy1 crosslinking and assess the impact of specific lung myofibroblast Thy1-deficiency, in vivo, in bleomycin-injured mouse lungs. …”
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11396
Gamma Irradiation of Plukenetia volubilis L. Seeds Promotes Several Changes during Its Germination and Vegetative Growth
Published 2023-01-01“…The establishment of genetic variability, through spontaneous mutations or induced mutations, can bring desirable and undesirable agronomic traits. …”
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11397
Nondestructive Detection of Moisture Content in Palm Oil by Using Portable Vibrational Spectroscopy and Optimal Prediction Algorithms
Published 2023-01-01“…Several preprocessing methods such as standard normal variant (SNV), multiplicative scatter correction (MSC), Savitzky–Golay first derivative (SGD1), Savitzky–Golay second derivative (SGD2) together with partial least square (PLS) regression techniques, full PLS, interval PLS (iPLS), synergy interval PLS (SiPLS), genetic algorithm PLS (GAPLS), and successive projection algorithm PLS (SPA-PLS) were comparatively employed to construct an optimum quantitative prediction model for moisture content in crude palm oil. …”
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11398
Semantic Modeling for SNPs Associated with Ethnic Disparities in HapMap Samples
Published 2014-03-01“…We found ethnicity-specific genes using the semantic modeling, and the majority of our findings was consistent with the previous studies - that an understanding of genetic variability explained ethnicity-specific disparities.…”
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11399
Combined interaction of fungicides binary mixtures: experimental study and machine learning-driven QSAR modeling
Published 2024-06-01“…The MLR model showed a good linear correlation between selected theoretical descriptors by the genetic algorithm and fungicidal activity. However, both ML-based models demonstrated better predictive performance than the MLR model. …”
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11400
Recipient sex and donor leukemic cell characteristics determine leukemogenesis in patient-derived models
Published 2025-01-01“… In acute myeloid leukemia (AML), leukemogenesis depends on cell-intrinsic genetic aberrations and thus, studies on AML require investigations in an in vivo setting as provided by patient derived xenografts (PDX) models. …”
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