Later-Life Mortality and Longevity in Late-18th and 19th-Century Cohorts. Where Are We Now, and Where Are We Heading? by Rick Mourist

“…Yet, later-life mortality and longevity are generally studied from a genetic perspective, while the social dimension has received less attention. …”
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CHEMOTYPE VERBOCCIDENTAFURAN IN Baccharis punctulata (Asteraceae): FURANIC SESQUITERPENES CORRELATION AND MOLECULAR DOCKING INTO THE BENZODIAZEPINE RECEPTOR by Jociani Ascari, Murilo S. de Oliveira, André L. Rüdiger, Elaine Elisabetsky, Domingos S. Nunes, Jorge Iulek, Dilamara R. Scharf, Gustavo Heiden

“…The variation of this compound found in male and female specimens may be associated to the existence of more than one type of chemotype, influenced by geographic variation, climatic conditions, stage of the vegetative cycle, genetic and ecological factors. The furanocadinan-type sesquiterpenes verboccidentafuran (1) and curzerene (2) have molecular descriptors with high similarities. …”
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A Corticobasal Syndrome Variant of Familial Creutzfeldt-Jakob Disease with Stroke-Like Onset by Ján Necpál, Martin Stelzer, Silvia Koščová, Michal Patarák

“…In general, the most common form is sporadic CJD; however, Slovakia is typical for a high percentage of genetic cases. We present an unusual case report of a 65-year-old man with a sudden, stroke-like onset of motor aphasia with right-sided levodopa unresponsive parkinsonism, alien hand, and other characteristic features of corticobasal syndrome (CBS), with rapid deterioration and death on the 32nd day of the disease. …”
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Influence of Androgen Receptor Gene CAG and GGC Polymorphisms on Male Sexual Function: A Cross-Sectional Study by Giacomo Tirabassi, Giovanni Corona, Sara Falzetti, Nicola delli Muti, Mario Maggi, Giancarlo Balercia

“…Clinical, biochemical, and genetic parameters were considered. Sexual assessment was performed using the International Index of Erectile Function (IIEF) which evaluates erectile function (EF), orgasmic function (OF), sexual desire (SD), intercourse satisfaction (IS), and overall satisfaction (OS). …”
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An Ensemble Feature Selection Approach-Based Machine Learning Classifiers for Prediction of COVID-19 Disease by Md. Jakir Hossen, Thirumalaimuthu Thirumalaiappan Ramanathan, Abdullah Al Mamun

“…Different feature selection approaches including chi-square test, recursive feature elimination (RFE), genetic algorithm (GA), particle swarm optimization (PSO), and random forest are evaluated for their effectiveness in enhancing the classification accuracy of the machine learning classifiers. …”
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Non-random mating behaviour between diverging littoral and pelagic three-spined sticklebacks in an invasive population from Upper Lake Constance by Tobias Zeidler, Albert Ros, Samuel Roch, Arne Jacobs, Juergen Geist, Alexander Brinker

“…Adaptive divergence and increased genetic differentiation among populations can lead to reproductive isolation. …”
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Feature Selection for Very Short-Term Heavy Rainfall Prediction Using Evolutionary Computation by Jae-Hyun Seo, Yong Hee Lee, Yong-Hyuk Kim

“…In comparative SVM tests using evolutionary algorithms, the results showed that genetic algorithm was considerably superior to differential evolution. …”
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Unravelling the TCRβ repertoire: a key to unlocking the immunopathogenesis and precision medicine in SLE by Qiao Zhou, Li Zeng, Zhixin Zhang, Jian Liu, Yichen Zhang, Yang An, Lijing Yang, Tianzuo Lan, Pengming He, Xueping Wen, Shaoping Deng

“…Objectives SLE is a multifaceted autoimmune disorder with a complex pathogenesis involving genetic, environmental and hormonal factors, which converge on immune dysregulation. …”
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Colitis in spondyloarthritis by Muhammed Hafis, Vikas Agarwal

“…Apart from the strong Class I human leukocyte antigen B27 link for both diseases, several new shared genetic risk loci are identified from genome-wide association studies. …”
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A Single Lung Transplant in a Patient with Fabry Disease: Causality or Far-Fetched? A Case Report by Martina Gaggl, Renate Kain, Peter Jaksch, Dominik Haider, Gerald Mundigler, Till Voigtländer, Raute Sunder-Plassmann, Paulus Rommer, Walter Klepetko, Gere Sunder-Plassmann

“…Later, a kidney biopsy revealed the diagnosis of Fabry disease, which was confirmed by enzymatic and genetic testing. Ultrastructural changes in a native lung biopsy were consistent with the diagnosis. …”
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Smart Cylindrical Dome Antenna Based on Active Frequency Selective Surface by Tongyu Ding, Shaoqing Zhang, Liang Zhang, Yanhui Liu

“…Moreover, in order to overcome the unavailable analytical synthesis caused by complex mutual coupling between columns, we develop a genetic algorithm based optimization system and conducted a serial of experiments to evaluate the high-gain, nulling, continuously steering, and frequency-invariant ability. …”
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GA-ARMA Model for Predicting IGS RTS Corrections by Mingyu Kim, Jeongrae Kim

“…We propose applying a genetic algorithm autoregressive moving average (GA-ARMA) model to predict the IGS RTS corrections during data loss periods. …”
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Eye Motility Alterations in Retinitis Pigmentosa by Raffaele Migliorini, Anna Maria Comberiati, Giovanni Galeoto, Manuela Fratipietro, Loredana Arrico

“…Therefore, the disorders of OM lead to a genetic origin.…”
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Targeting T-Cell Activation for Malaria Immunotherapy: Scoping Review by Balsa Nobility Gustifante, Shafia Khairani, Nisa Fauziah, Silvita Fitri Riswari, Afiat Berbudi

“…Malaria remains a critical global health issue due to high mortality rates, drug resistance, and low treatment efficacy. The genetic variability of <i>Plasmodium</i> proteins complicates the development of long-lasting immunity, as it impedes the human immune system’s ability to sustain effective responses. …”
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Variable stressor exposure shapes fitness within and across generations by Marcus Lee

“…Abstract Environmental variation has long been considered a key driver of evolutionary change, predicted to shape different strategies, such as genetic specialization, plasticity, or bet-hedging to maintain fitness. …”
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Acute hemorrhagic conjunctivitis outbreaks associated with Coxsackievirus A-24 in India, 2023 by Nutan A. Chavan, Pooja Shinde, Sanjaykumar Tikute, Rajlakshmi Vishwanathan, Avinash R. Deoshatwar, Yogesh K. Gurav, Rishabh Waghchaure, Nishat H. Ahmed, Vannavada S. Rani, Vikram Khan, Aditya Kelkar, Harsh H. Jain, Amita Jain, Mallika Lavania, Babasaheb V. Tandale

“…This study aimed to identify the aetiological agent associated with AHC in 2023, genetically characterize the agent and describe the clinical presentation. …”
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Exception to the Rule: Genomic Characterization of Naturally Occurring Unusual Vibrio cholerae Strains with a Single Chromosome by Gary Xie, Shannon L. Johnson, Karen W. Davenport, Mathumathi Rajavel, Torsten Waldminghaus, John C. Detter, Patrick S. Chain, Shanmuga Sozhamannan

“…The genetic make-up of most bacteria is encoded in a single chromosome while about 10% have more than one chromosome. …”
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The interface of depression and diabetes: treatment considerations by Giuseppe Fanelli, Emanuel Raschi, Gaye Hafez, Silke Matura, Carmen Schiweck, Elisabetta Poluzzi, Carlotta Lunghi

“…Depression and diabetes often co-occur and share genetic, lifestyle, and psychosocial risk factors. …”
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Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy by Helena Escobar, Silvia Di Francescantonio, Julia Smirnova, Robin Graf, Stefanie Müthel, Andreas Marg, Alexej Zhogov, Supriya Krishna, Eric Metzler, Mina Petkova, Oliver Daumke, Ralf Kühn, Simone Spuler

“…Mutations in the DYSF gene cause a panoply of genetic muscular dystrophies. We targeted a frequent loss-of-function, DYSF exon 44, founder frameshift mutation with mRNA-mediated delivery of SpCas9 in combination with a mutation-specific sgRNA to primary muscle stem cells from two homozygous patients. …”
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Vitamin D and Selenium: Review of Clinical Trials of Synergistic Effects on Thyroid Antibody Levels and Disease Progression in Hashimoto’s Thyroiditis by Agnieszka Starzyk, Piotr Charzewski

“… Introduction: Hashimoto's Thyroiditis (HT) is a common autoimmune thyroid disorder caused by genetic predispositions and environmental factors, such as iodine imbalance, selenium deficiency, and stress. …”
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