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11281
The ethics of theft: Reevaluating the impacts of floral larceny on plant reproductive success
Published 2025-01-01“…By altering pollinator behavior, floral larceny may reduce geitonogamy, potentially enhancing genetic diversity. Additionally, factors such as pollinator type, plant mating system, and pollen limitation were identified as key moderators of these effects. …”
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11282
Multi-Item Multiperiodic Inventory Control Problem with Variable Demand and Discounts: A Particle Swarm Optimization Algorithm
Published 2014-01-01“…To assess the efficiency of the proposed MOPSO, the model is solved using multi-objective genetic algorithm (MOGA) as well. A large number of numerical examples are generated at the end, where graphical and statistical approaches show more efficiency of MOPSO compared with MOGA.…”
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11283
Challenges in Diagnosing Intrahepatic Cholangiolithiasis in a 39-Year-Old Patient
Published 2024-12-01“…Cholangiolithiasis occurs in more than half of cases of primary sclerosing cholangitis and can be both a complication and a cause of secondary sclerosing cholangitis, maintaining inflammation in the ducts and facilitating stone formation. Genetic mutations are known to contribute to the development of gallstones in young patients, including low phospholipid-associated cholelithiasis. …”
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11284
A Multifactory Integrated Production and Distribution Scheduling Problem with Parallel Machines and Immediate Shipments Solved by Improved Whale Optimization Algorithm
Published 2018-01-01“…Moreover, it confirms the capability of the improved whale optimization algorithm (IWOA) to solve the medium-scale instances; however, the results indicate the better performance of genetic algorithm (GA) for the large-scale instances.…”
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11285
Differential Impact of Stress Reduction Programs upon Ambulatory Blood Pressure among African American Adolescents: Influences of Endothelin-1 Gene and Chronic Stress Exposure
Published 2012-01-01“…If these preliminary findings are replicated via ancillary analyses of archival databases and then via efficacy trials, selection of behavioral prescriptions for prehypertensives will be edging closer to being guided by individual's underlying genetic and environmental factors incorporating the healthcare model of personalized preventive medicine.…”
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11286
Estrogen-dependent activation of TRX2 reverses oxidative stress and metabolic dysfunction associated with steatotic disease
Published 2025-01-01“…Furthermore, disruption of TRX2, either pharmacologically using auranofin or through genetic interference, was sufficient to counteract the protective effects of estrogens, highlighting a potential mechanism through which estrogens may prevent or slow MASLD progression.…”
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11287
Soft Measurement of Wastewater Treatment System Based on PSOGA-WNN
Published 2023-01-01“…To accurately predict the SS<sub>eff</sub> (effluent SS) content and COD<sub>eff</sub> (effluent COD) concentration in water quality parameters and further improve the water quality early warning mechanism,this paper proposes the PSOGA-WNN soft measurement model of paper wastewater effluent quality to obtain the main water quality technical parameters,COD<sub>inf</sub> (influent COD),Q (influent flow),pH (influent pH),SS<sub>inf</sub> (influent SS),T (influent temperature),DO (influent dissolved oxygen),COD<sub>eff</sub>,and SS<sub>eff,</sub> for predicting the quality of wastewater from the wastewater treatment plant.Among them,the prediction results of PSOGA-WNN are compared with the neural networks of PSO-WNN,GA-WNN,and PSOGA-BP.The results show that the PSOGA-WNN neural network has the highest prediction accuracy,which indicates that the PSOGA hybrid parameter optimization algorithm based on the genetic algorithm and particle swarm algorithm has obvious superiority in optimizing the prediction accuracy of the model.The WNN neural network has certain advantages over BP neural network in terms of fitting degree as well as error accuracy and is an effective means of simulation prediction.…”
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11288
A Data Fusion System for Simulation of Critical Scenarios and Decision-Making
Published 2019-11-01“…This document describes an investigation product resulted in a simulation system, based on a combination of fuzzy logic, genetic algorithms and decision trees which let modelled and simulated various entities and their automatic response according to simulated patterns and situations, in which, through operators, decision maker can modify entities behaviour, according to parameterized restrictions and physical conditions. …”
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11289
pVAXhsp65 Vaccination Primes for High IL-10 Production and Decreases Experimental Encephalomyelitis Severity
Published 2017-01-01“…Considering the presence of an immune response directed to heat shock proteins (hsps) in autoimmune diseases and the immunoregulatory potential of these molecules, we evaluated the effect of a previous immunization with a genetic vaccine containing the mycobacterial hsp65 gene on EAE development. …”
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11290
Uncommon BRAF Mutations Associated with Durable Response to Immunotherapy in Patients with Metastatic Melanoma
Published 2017-01-01“…Melanoma is a disease process which has been increasing in incidence over the past three decades and metastatic melanoma carries a poor prognosis. Through genetic studies of this disease, it has been determined that the BRAF V600 mutation plays a major role in the pathophysiology of the disease and this has led to the utilization of targeted therapy (BRAF and MEK inhibitors) in its treatment. …”
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11291
Electric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury.
Published 2025-01-01“…In addition to partial anatomical restoration, ACB waveforms conferred partial restoration of visual function as measured by pattern electroretinogram recordings and local field potential recordings in the superior colliculus-and did so without the need for genetic manipulation. Our work suggests that exogenous electric field application can override cell-intrinsic and cell-extrinsic barriers to axon regeneration, and that electrical stimulation performed with specific ACB waveforms may be an effective strategy for directing anatomical and functional restoration after CNS injury.…”
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11292
Evaluation of a Simple Antibiotic-Free Cryopreservation Protocol for Drone Semen
Published 2025-01-01“…The cryopreservation of drone semen presents a promising solution for preserving genetic diversity and supporting breeding programs without live animal transport risks. …”
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11293
Congenital Anomalies and Termination of Pregnancy in Iran
Published 2012-01-01“…The proportion of other screening tests including amniocentesis and genetic tests were 2.8 and 4.6 percent, respectively. …”
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11294
Chromosome-level Genome Assembly of Korean Long-tailed Chicken and Pangenome of 40 Gallus gallus Assemblies
Published 2025-01-01“…Notably, our KLC assembly contributed 1,919,925 bp of new sequences to the pangenome, underscoring the unique genetic makeup of this breed. Furthermore, in comparison with the pangenome, we identified 36,818 structural variants in KLC, which included 2,529 insertions, 27,743 deletions, and 6,546 of either insertions or deletions shorter than 1 kb. …”
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11295
The Utah Population Database. The Legacy of Four Decades of Demographic Research
Published 2021-09-01“…The UPDB is one of the world’s richest sources of linked population-based information for demographic, genetic, and epidemiological studies at the Individual-level. …”
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11296
Recent Pathophysiological Aspects of Peyronie’s Disease: Role of Free Radicals, Rationale, and Therapeutic Implications for Antioxidant Treatment—Literature Review
Published 2017-01-01“…Although its etiology is not completely known, there is general consensus that PD is genetically transmitted and secondary to penile trauma. …”
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11297
Proton Pump Inhibitors and Dementia: Physiopathological Mechanisms and Clinical Consequences
Published 2018-01-01“…Dementia and AD are chronic neurodegenerative conditions with a complex physiopathology involving both genetic and environmental factors. Recent clinical studies have shown that proton pump inhibitors (PPIs) are associated with risk of dementia, including AD. …”
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11298
A universal and wide-range cytosine base editor via domain-inlaid and fidelity-optimized CRISPR-FrCas9
Published 2025-02-01“…Abstract CRISPR-based base editor (BE) offer diverse editing options for genetic engineering of microorganisms, but its application is limited by protospacer adjacent motif (PAM) sequences, context preference, editing window, and off-target effects. …”
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11299
Pivotal Cytoprotective Mediators and Promising Therapeutic Strategies for Endothelial Progenitor Cell-Based Cardiovascular Regeneration
Published 2016-01-01“…Additionally, to enhance EPC’s functional capacity at ischemic sites, multiple strategies for cell survival should be considered, that is, preconditioning of EPCs with function-targeting drugs including natural compounds and hormones, virus mediated genetic modification, combined therapy with other stem/progenitor cells, and conglomeration with biomaterials. …”
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11300
Influence of Hysteresis on the Vibration Control of a Smart Beam with a Piezoelectric Actuator by the Bouc–Wen Model
Published 2020-01-01“…Furthermore, the Bouc–Wen model is adopted to describe the hysteresis property of a smart beam and the hysteresis parameters of the hysteresis model are identified with a genetic algorithm. Based on the identification results, the hysteresis model is validated to represent the hysteresis property of the smart beam. …”
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