Immunosuppressants in modern approaches to treatment of inflammatory bowel diseases by O. B. Schukina, A. G. Kharitonov, A. M. Kharitidis, T. E. Ivashchenko, Yu. A. Nasykhova, T. V. Gabrusskaya, A. Yu. Baranovsky

“…There is no need of study for genetic mutations before prescription of thiopurines, however application of effective methods of evaluation of prognosis of bone marrow toxicity development remains an actual issue. …”
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Big Data-Driven Based Real-Time Traffic Flow State Identification and Prediction by Hua-pu Lu, Zhi-yuan Sun, Wen-cong Qu

“…Traffic flow state quantification, the basis of traffic flow state identification, is achieved by a SAGA-FCM (simulated annealing genetic algorithm based fuzzy c-means) based traffic clustering model. …”
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Risk of Atherosclerosis and Helicobacter pylori Infection according to CD14 Promotor Polymorphism in Healthy Korean Population by Sung-Goo Kang, Woo Chul Chung, Sang-Wook Song, Kyu Re Joo, Hyewon Lee, Donghoon Kang, Joune Seup Lee, Kang-Moon Lee

“…The promotor polymorphism at −159C/T of the CD14 gene was determined by PCR-restriction fragment length polymorphism analysis. According to genetic polymorphism and H. pylori infection, we analyzed the risk of atherosclerosis. …”
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Biophysical Profiling of Tumor Cell Lines by Frederick Coffman, Rachid Hamid, Marion C. Cohen, Ralph Garippa, Stanley Cohen

“…Despite significant differences in genetic profiles, cancer cells share common phenotypic properties, including membrane-associated changes that facilitate invasion and metastasis. …”
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Mitochondrial abnormalities as a target of intervention in acute myeloid leukemia by Elissa Tjahjono, Megan R. Daneman, Bernadetta Meika, Alexey V. Revtovich, Natalia V. Kirienko

“…AML prognosis is often poor, and relapse often occurs after initial remission. Recurrent genetic abnormalities underlying this disease and the presence of leukemic stem cells complicate disease treatment. …”
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Optimization Approach for Yard Crane Scheduling Problem with Uncertain Parameters in Container Terminals by Wenqian Liu, Xiaoning Zhu, Li Wang, Baicheng Yan, Xuewei Zhang

“…Subsequently, two algorithms based on certain rules are proposed to obtain the yard crane operation scheme in the deterministic environment, which are taken as the basic solution in the uncertain conditions, and then a tailored genetic algorithm is adopted to find the optimal solution with good adaptability to the uncertain scenarios. …”
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Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study by Narcisse Elenga, Aurélie Adeline, John Balcaen, Tania Vaz, Mélanie Calvez, Anne Terraz, Laetitia Accrombessi, Gabriel Carles

“…Sickle cell disease is a serious genetic disorder affecting 1/235 births in French Guiana. …”
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Omega-3 Fatty Acids and Vitamin D in Cardiology by Norbert Güttler, Kirila Zheleva, Mariana Parahuleva, Ridvan Chasan, Mehmet Bilgin, Christiane Neuhof, Mehmet Burgazli, Bernd Niemann, Ali Erdogan, Andreas Böning

“…Experimental studies show effects on membrane structure and associated functions, ion channel properties, genetic regulation, and production of anti-inflammatory mediators. …”
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Endometrial Cancer and Hypermethylation: Regulation of DNA and MicroRNA by Epigenetics by Kouji Banno, Iori Kisu, Megumi Yanokura, Kenta Masuda, Yusuke Kobayashi, Arisa Ueki, Kosuke Tsuji, Wataru Yamagami, Hiroyuki Nomura, Nobuyuki Susumu, Daisuke Aoki

“…However, several aspects of the mechanism of carcinogenesis in the endometrium remain unclear. Associations with genetic variation and mutations of cancer-related genes have been shown, but these do not provide a complete explanation. …”
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A New Hope in Immunotherapy for Malignant Gliomas: Adoptive T Cell Transfer Therapy by Dong-Sup Chung, Hye-Jin Shin, Yong-Kil Hong

“…Moreover, enhanced biologic functions of T cells generated by genetic engineering and modified immunosuppressive microenvironment of host by homeostatic T cell expansion and/or elimination of immunosuppressive cells and molecules can induce more potent antitumor T cell responses and make this strategy hold promise in promoting a patient response for malignant glioma treatment. …”
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Synergic Interaction of Rifaximin and Mutaflor (Escherichia coli Nissle 1917) in the Treatment of Acetic Acid-Induced Colitis in Rats by Artur Dembiński, Zygmunt Warzecha, Piotr Ceranowicz, Marcin Dembiński, Jakub Cieszkowski, Tomasz Gosiewski, Małgorzata Bulanda, Beata Kuśnierz-Cabala, Krystyna Gałązka, Peter Christopher Konturek

“…Inflammatory bowel disease results from the dysregulation of immune response to environmental and microbial agents in genetically susceptible individuals. The aim of the present study was to examine the effect of rifaximin and/or Mutaflor (Escherichia coli Nissle 1917, EcN) administration on the healing of acetic acid-induced colitis. …”
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Acquired Myelodysplasia or Myelodysplastic Syndrome: Clearing the Fog by Ethan A. Natelson, David Pyatt

“…They are typically considered neoplasms because of frequent genetic aberrations and patient-limited survival with progression to acute myeloid leukemia (AML) or death related to the consequences of bone marrow failure including infection, hemorrhage, and iron overload. …”
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Evaluation of Contemporary Computational Techniques to Optimize Adsorption Process for Simultaneous Removal of COD and TOC in Wastewater by Areej Alhothali, Hifsa Khurshid, Muhammad Raza Ul Mustafa, Kawthar Mostafa Moria, Umer Rashid, Omaimah Omar Bamasag

“…This study was aimed at evaluating the artificial neural network (ANN), genetic algorithm (GA), adaptive neurofuzzy interference (ANFIS), and the response surface methodology (RSM) approaches for modeling and optimizing the simultaneous adsorptive removal of chemical oxygen demand (COD) and total organic carbon (TOC) in produced water (PW) using tea waste biochar (TWBC). …”
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Acquired Vulvar Lymphangioma Following CO2 Laser Treatment for Sebaceous Gland Nevus in a 10-Year-Old Girl: A Case Report by Luo Y, Chen W, Xu D, Chen S, Ma S

“…Histopathological examination and genetic testing confirmed Our diagnosis of acquired vulvar lymphangioma with lymphedema.Keywords: acquired vulvar lymphangiectasia, lymphangioma, lymphedema…”
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A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD by Tristan X. McCallister, Colin K. W. Lim, Mayuri Singh, Sijia Zhang, Najah S. Ahsan, William M. Terpstra, Alisha Y. Xiong, M. Alejandra Zeballos C, Jackson E. Powell, Jenny Drnevich, Yifei Kang, Thomas Gaj

“…Abstract An abnormal expansion of a GGGGCC (G4C2) hexanucleotide repeat in the C9ORF72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two debilitating neurodegenerative disorders driven in part by gain-of-function mechanisms involving transcribed forms of the repeat expansion. …”
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Clustering Large-Scale Biomedical Data to Model Dynamic Accumulation Processes in Disease Progression and Anti-Microbial Resistance Evolution by Kazeem A. Dauda, Olav N. L. Aga, Iain G. Johnston

“…Existing approaches for accumulation modelling are typically limited either in the number of features they consider or their ability to characterise interactions between these features – a limitation for the large-scale genetic and/or phenotypic datasets often found in modern biomedical applications. …”
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Energy-Efficient and Fault-Tolerant Control of a Six-Axis Robot Based on AI Models by Patryk Nowak, Zoran Pandilov

“…In the robot’s control system, artificial intelligence methods are also applied. Specifically, a genetic algorithm is used to generate learning data for the selection of the optimal kinematic configuration of the robot, and a multilayer perceptron is utilized to predict the parameters of the defined reward function. …”
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A Case of Von Hippel–Lindau Disease with Bilateral Pheochromocytoma and Ectopic Hypersecretion of Intact Parathyroid Hormone in an Adolescent Girl by Rym Belaid, Ibtissem Oueslati, Melika Chihaoui, Meriem Yazidi, Wafa Grira, Fatma Chaker

“…MIBG scintigraphy exhibited a high accumulation of the tracer in both adrenal tumors. Genetic testing revealed a mutation of the VHL gene. …”
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Community Participation Process for the Sustainable Business Development of Local Wisdom Learning Centers by Thussaneeya Boripis, Shubham Pathak, Wachiraporn Poungjinda, Josephine Chen Yii Ling

“…This study explores the objectives to explore, analyze, and examine the local wisdom centers in response to the Royal Initiative of the Plant Genetic Conservation Project as a result of the seventh year (October 1, 2021 – September 30, 2026) in line with the objectives of the Public Works Department (PWDs). …”
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Clinical Onset of Celiac Disease after an Episode of Campylobacter jejuni Enteritis by EF Verdu, M Mauro, J Bourgeois, D Armstrong

“…The present case suggests that the clinical expression of CD can be unmasked by an acute gastrointestinal infection and supports the hypothesis that environmental factors other than gliadin may play a role in the clinical onset of CD in a genetically susceptible host. The increasing availability of serological testing and upper endoscopy has led to increasingly frequent diagnoses of CD and recognition that it may mimic IBS. …”
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