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11201
Ensete ventricosum: A Multipurpose Crop against Hunger in Ethiopia
Published 2020-01-01“…Moreover, enset shows high genetic diversity within a population which in turn renders resilience and food security against the ever-changing environmental factors and land use dynamics. …”
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11202
Random Mutagenesis of the Aspergillus oryzae Genome Results in Fungal Antibacterial Activity
Published 2013-01-01“…Because the genome of A. oryzae has been sequenced and systems are available for genetic transformation of this organism, targeted as well as random mutations may be introduced to facilitate the discovery of novel antibacterial compounds using this system.…”
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11203
Genotypes of <i>Sechium</i> spp. as a Source of Natural Products with Biological Activity
Published 2024-12-01“…The inedible genotypes are in a fragile ecological niche, since they are not used by rural inhabitants. A rescue and genetic crossing program was designed to identify uses that favor their conservation due to their content of bioactive secondary metabolites (Sm) for health. …”
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11204
Advances in the Development and Application of Human Organoids: Techniques, Applications, and Future Perspectives
Published 2025-01-01“…These microstructures are invaluable for biomedical research due to their ability to closely mimic the complexity of native tissues while retaining human genetic material. This fidelity to native organ systems positions organoids as a powerful tool for advancing our understanding of human biology and for enhancing preclinical drug testing. …”
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11205
Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade
Published 2025-02-01“…Our approach involved the use of genetic engineering to the long-lasting production of PD-1 and the brain-specific peptide angiopep-2 on the surface of EVs. …”
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11206
Genomic and phenotypic stability of fusion-driven pediatric sarcoma cell lines
Published 2025-01-01“…Here, we hypothesize that oligomutated pediatric sarcoma cell lines mainly driven by a fusion transcription factor, such as Ewing sarcoma (EwS), are genetically and phenotypically more stable than the previously investigated adult carcinoma cell lines. …”
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11207
Quantum Dots Do Not Alter the Differentiation Potential of Pancreatic Stem Cells and Are Distributed Randomly among Daughter Cells
Published 2013-01-01“…We report here that QDs offered an efficient and nontoxic way to label pancreatic stem cells without genetic modifications. In summary, QD nanocrystals are a promising tool for stem cell labeling and facilitate tracking of transplanted cells in animal models.…”
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11208
A Case of Physically Abused OCD Patient Who Physically Abused Her own Child
Published 2013-08-01“…It was suggested that along with genetic factors various psychosocial factors may play a role in the development of Obsessive Compulsive Disorder (OCD). …”
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11209
It Is All in the Genes: A Story of Unexpected Survival in a 67-Year-Old Male with Metastatic Pancreatic Cancer
Published 2023-01-01“…His survival far exceeded the median overall survival metrics. Genetic testing revealed a pathogenic heterozygous germline BRCA2 6643delT p.…”
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11210
Barriers to the adoption of multiple agricultural innovations: insights from Bt cotton, wheat seeds, herbicides and no-tillage in Pakistan
Published 2024-12-01“…This study investigates the potential reasons that stop smallholder farming households from adopting genetically engineered seeds (Bt cotton and improved wheat seeds), herbicides resulting from cutting-edge technologies, and no-tillage farming. …”
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11211
An Unusual Presentation of a Myocardial Crypt in Hypertrophic Cardiomyopathy
Published 2014-01-01“…We present a case of a 56-year-old man who had positive family history of HCM who was a carrier of the genetic MYH-7 2770 G > C, exon 23 mutation. Transthoracic echocardiography showed thickening of the interventricular septum (16 mm) and in particular the basal septum. …”
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11212
Later-Life Mortality and Longevity in Late-18th and 19th-Century Cohorts. Where Are We Now, and Where Are We Heading?
Published 2017-01-01“…Yet, later-life mortality and longevity are generally studied from a genetic perspective, while the social dimension has received less attention. …”
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11213
Later-Life Mortality and Longevity in Late-18th and 19th-Century Cohorts. Where Are We Now, and Where Are We Heading?
Published 2017-01-01“…Yet, later-life mortality and longevity are generally studied from a genetic perspective, while the social dimension has received less attention. …”
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11214
Blood Vessel Segmentation and Classification of Diabetic Retinopathy with Machine Learning-Based Ensemble Model
Published 2024-09-01“…The incidence of diabetes has increased in recent times due to factors such as obesity and genetic predisposition. Diabetes wears out the eye vessels over time. …”
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11215
Novel MFSD8 Variants in a Chinese Family with Nonsyndromic Macular Dystrophy
Published 2021-01-01“…This study enlarged the MFSD8 gene mutant spectrum and might provide more accurate genetic counseling for this family.…”
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11216
Screening and Selection of Native Lactic Acid Bacteria Isolated from Chilean Grapes
Published 2025-01-01“…Morphological assessments led to the selection of 23 isolates, which were genetically identified as <i>Levilactobacillus brevis</i> (65% abundance) and <i>Leuconostoc mesenteroides</i> (35% abundance). …”
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11217
An Application of DC Motor Modelled Classical Sliding Mode Control with Moving Sliding Surface to Rotary Inverted Pendulum System
Published 2024-10-01“…The sliding surface's slope was computed based on the system's dynamics. The genetic algorithm was utilized to determine the ideal values for the coefficients employed in the control structure. …”
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11218
Epigenetic Markers of Renal Function in African Americans
Published 2013-01-01“…To better understand how these methylation markers play a role in kidney function, we measured 26,428 DNA methylation sites in 972 African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA) study. …”
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11219
Predicting Patients’ Revisit Intention Based on Satisfaction Scores: Combination of Penalized Regression and Neural Networks
Published 2025-01-01“…In addition to feature selection models such as Random Forest, Genetic Algorithm, and Lasso Regression, the study employs various methods, including Neural Networks, Support Vector Machines, Decision Trees, k-Nearest Neighbors, Rule-based systems, and Naive Bayes algorithms. …”
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11220
Hydrogeochemical Characteristics and Genesis of the Chazi Geothermal Field Area in Tibet
Published 2022-01-01“…These results provide a scientific theoretical basis for improving the genetic mechanism of high-temperature geothermal systems in the study area. …”
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