Autoantibodies in COVID-19: implications for disease severity and clinical outcomes by Yannick Galipeau, Curtis Cooper, Marc-André Langlois, Marc-André Langlois

“…Few pathogens have historically been subjected to as intense scientific and clinical scrutiny as SARS-CoV-2. The genetic, immunological, and environmental factors influencing disease severity and post-infection clinical outcomes, known as correlates of immunity, remain largely undefined. …”
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An Intrusion Detection System Based on Deep Learning and Metaheuristic Algorithm for IOT by Bahman Sanjabi, Mahmood Ahmadi

“…In this paper, a method is presented that uses meta-heuristic algorithms such as genetic algorithm, particle swarm optimization, artificial bee colony and gray wolf to find the optimal hyperparameters for the deep learning network and the intrusion detection system is created based on these hyperparameters. …”
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Efficiency and Reliability Analysis of Self-Adaptive Two-Stage Fuzzy Control System in Complex Traffic Environment by Mingzhi Wang, Xianyu Wu, He Tian, Jie Lin, Meimei He, Liuqing Ding

“…Aiming at the problems of the parameters of membership functions empirical settings and insufficient response to the real-time fluctuation in traffic flow, the controller introduces an improved hybrid genetic algorithm to solve it and enable the controller to self-learn. …”
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A novel uORF regulates folliculin to promote cell growth and lysosomal biogenesis during cardiac stress by Maja Bencun, Laura Spreyer, Etienne Boileau, Jessica Eschenbach, Norbert Frey, Christoph Dieterich, Mirko Völkers

“…Our work has identified a regulatory upstream open reading frame (uORF) localized in the 5′UTR of the FLCN mRNA. These small genetic elements are important regulators of protein expression. …”
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The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling by Kara A Nelson, Kari F Lenhart, Lauren Anllo, Stephen DiNardo

“…To address this, we investigated the formation of a genetically tractable niche, the Drosophila Posterior Signaling Center (PSC), the assembly of which had not been previously explored. …”
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Pasteurisation temperatures effectively inactivate influenza A viruses in milk by Jenna Schafers, Caroline J. Warren, Jiayun Yang, Junsen Zhang, Sarah J. Cole, Jayne Cooper, Karolina Drewek, B. Reddy Kolli, Natalie McGinn, Mehnaz Qureshi, Scott M. Reid, Thomas P. Peacock, Ian Brown, Joe James, Ashley C. Banyard, Munir Iqbal, Paul Digard, Edward Hutchinson

“…We then show that an H5N1 HPAIV in milk is effectively inactivated by a comparable treatment, even though its genetic material remains detectable. We conclude that pasteurisation conditions should effectively inactivate H5N1 HPAIV in cows’ milk, but that unpasteurised milk could carry infectious influenza viruses.…”
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Severe infestation by tropical bedbugs (Cimex hemipterus) in Medellín, Colombia. Case series by Julián Felipe Porras-Villamil, Sandra Sáez-Durán, María Trelis-Villanueva, Rubén Bueno-Marí, Màrius Vicent Fuentes

“…This paper presents three clinical cases secondary to a tropical bedbug infestation that were morphologically and genetically identified. Case presentation: A three-member family (mother aged 53 years and two daughters aged 25 and 22 years) living in Medellín (Colombia) requested a private teleconsultation due to generalized pruritus and psychological symptoms (feeling of isolation, anxiety, difficulty sleeping, and jumpiness). …”
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Transcriptome responses to Ralstonia solanacearum infection in tetraploid potato by Zhuo Chen, Shunwei Shao, Xi Zhu, Yu Zhang, Zhendong Lan, Hui Jin

“…Gene ontology and KEGG analyses provided further insights into the genetic basis and molecular mechanisms underlying plant defense against R. solanacearum disease. …”
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Stroma-derived Dickkopf-1 contributes to the suppression of NK cell cytotoxicity in breast cancer by Seunghyun Lee, Biancamaria Ricci, Jennifer Tran, Emily Eul, Jiayu Ye, Qihao Ren, David Clever, Julia Wang, Pamela Wong, Michael S. Haas, Sheila A. Stewart, Cynthia X. Ma, Todd A. Fehniger, Roberta Faccio

“…We find DKK1 to be expressed by tumor cells and cancer-associated fibroblasts (CAFs) in patient samples and orthotopic breast tumors, and in bone. By using genetic approaches, we find that bone-derived DKK1 contributes to the systemic DKK1 elevation in tumor-bearing female mice, while CAFs contribute to DKK1 at primary tumor site. …”
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Longitudinal genomic profiling using liquid biopsies in metastatic nonsquamous NSCLC following first line immunotherapy by Haolun Ding, Min Yuan, Yaning Yang, Xu Steven Xu

“…Using ctDNA data from IMpower150 study, we examined genetic changes in metastatic non-squamous NSCLC post-first-line immunotherapy. …”
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A Classification of Basic Helix-Loop-Helix Transcription Factors of Soybean by Karen A. Hudson, Matthew E. Hudson

“…The challenge for future research remains to define functions for the bHLH factors encoded in the soybean genome, which may allow greater flexibility for genetic selection of growth and environmental adaptation in this widely grown crop.…”
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Diversity and bioindicators of natural enemies in organic paddy fields implementing habitat modification by Setyadin Yuris, Leksono Amin Setyo, Tarno Hagus

“…Organic systems are a viable alternative characterized by organic fertilizers and biopesticides, avoiding genetically modified microorganisms and promoting biodiversity. …”
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Oligodendrocyte Injury in Multiple Sclerosis. by Mateo Përgjegji, Klei Bame, Ketrina Ceka, Jera Cenalia , Sibora Bërdica , Teona Bushati

“…This disease arises from a complex interplay of genetic predispositions and environmental triggers that drive immune-mediated damage to oligodendrocytes and myelin proteins. …”
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Brief Overview of a Decade of Genome-Wide Association Studies on Primary Hypertension by Afifah Binti Azam, Elena Aisha Binti Azizan

“…With major advancement in high-throughput genotyping technology, genome-wide association study (GWAS) has become a powerful tool for researchers studying genetically complex diseases. GWASs work through revealing links between DNA sequence variation and a disease or trait with biomedical importance. …”
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Methodology and Results of Detailed 3D Seismic Exploration in the Zhezkazgan Ore District by Arman Sirazhev, Sara Istekova, Dina Tolybaeva, Kuanysh Togizov, Raushan Temirkhanova

“…We carried out a marketing review in Kazakhstan and uncovered an increased interest among subsoil use companies in 3D seismic exploration technology to investigate existing mining objects of different genetic types. These results demonstrate the expediency of 3D seismic exploration aimed at identifying ore targets.…”
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Mitochondrial Stress Signalling: HTRA2 and Parkinson's Disease by Enrico Desideri, L. Miguel Martins

“…Mitochondria are cellular energy generators whose activity requires a continuous supply of oxygen. Recent genetic analysis has suggested that defects in mitochondrial quality control may be key factors in the development of Parkinson’s disease (PD). …”
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Multilocus Sequence Typing for Interpreting Blood Isolates of Staphylococcus epidermidis by Prannda Sharma, Ashley E. Satorius, Marika R. Raff, Adriana Rivera, Duane W. Newton, John G. Younger

“…Three machine learning algorithms (classification regression tree, support vector machine, and nearest neighbor) were employed. Genetic variability was substantial between isolates, with 44 sequence types found in 100 isolates. …”
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Exploring the prognosis of calponin h1 in carcinogenesis: A novel target in biomedical research by Roshna Sankar, Sharon John, Priya Devi, Sameer Gupta, Shalini Gupta

“…Consequently, variations in its expression levels in different malignancies are elucidated, along with an exploration of the associated genetic pathways, by shedding light on their potential impact on prognosis in malignancies.…”
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Addressing challenges in the implementation of precision oncology: An in-depth examination of limitations and disparities in the treatment of non-small cell lung cancer in the Braz... by Luma Princess Schneider, Jean Henri Maselli-Schoueri, Barbara de Souza Gutierres Aguiar, Pedro Nazareth Aguiar, Auro del Giglio

“…Precision oncology (PO) has significantly advanced lung cancer treatment by enabling personalised therapy based on genetic mutations. However, equitable access to molecular testing and targeted therapies remains a challenge, particularly in resource-limited settings such as the Brazilian Public Health System (SUS). …”
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Microcystic Changes in the Retinal Internal Nuclear Layer Associated with Optic Atrophy: A Prospective Study by Benjamin Wolff, Georges Azar, Vivien Vasseur, José-Alain Sahel, Catherine Vignal, Martine Mauget-Faÿsse

“…Moreover, their incidence was found to be dependent upon the cause of OA, with the highest incidence occurring in genetic OA.…”
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