The rs1634330 Polymorphisms in the SOST Gene Are Associated with Body Composition in Chinese Nuclear Families with Male Offspring by Luyue Qi, Lianyong Liu, Li Li, Weiwei Hu, Wenzhen Fu, Ji Hu, Youjia Xu, Zhenlin Zhang

“…Our results showed that the genetic variation in the SOST gene may contribute to variations in the body composition of Chinese male offspring.…”
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Bio-primed machine learning to enhance discovery of relevant biomarkers by David M. Henke, Alexander Renwick, Joseph R. Zoeller, Jitendra K. Meena, Nicholas J. Neill, Elizabeth A. Bowling, Kristen L. Meerbrey, Thomas F. Westbrook, Lukas M. Simon

“…This method holds promise for advancing personalized medicine by uncovering novel therapeutic targets and understanding the complex interplay of genetic and molecular factors in disease.…”
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Muscarinic ACh Receptors Contribute to Aversive Olfactory Learning in Drosophila by Bryon Silva, Claudia Molina-Fernández, María Beatriz Ugalde, Eduardo I. Tognarelli, Cristian Angel, Jorge M. Campusano

“…Our results show that pharmacological and genetic blockade of mAChRs in MB disrupts olfactory aversive memory in larvae. …”
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Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma by Ana Almazán-Moga, Patricia Zarzosa, Isaac Vidal, Carla Molist, Irina Giralt, Natalia Navarro, Aroa Soriano, Miguel F. Segura, Arantza Alfranca, Javier Garcia-Castro, José Sánchez de Toledo, Josep Roma, Soledad Gallego

“…Furthermore, cells contained in spheres and holoclones showed significant Hedgehog pathway induction, the inhibition of which (pharmacologic or genetic) impairs the formation of both holoclones and spheres. …”
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Capsular polysaccharide restrains type VI secretion in Acinetobacter baumannii by Nicolas Flaugnatti, Loriane Bader, Mary Croisier-Coeytaux, Melanie Blokesch

“…This T6SS impairment is further enhanced when CPS is overproduced due to genetic modifications or antibiotic treatment. Furthermore, we demonstrate that the bacterium adjusts the level of the T6SS inner tube protein Hcp according to its secretion capacity, by initiating a degradation process involving the ClpXP protease. …”
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RESPONSE OF WHEAT TO DIFFERENT ABIOTIC STRESS CONDITIONS: A REVIEW by Harikala Paudel, Radhakrishna Bhandari, Anjali Dhakal, Shivalal Nyaupane, Binod Panthi, Mukti Ram Poudel

“…A proper study of these effects and responses at the genetic and molecular level is necessary to cope with the existing yield gap in a farmer’s field as compared to normal conditions. …”
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Understanding secondary hypogammaglobulinemia and its implications for cancer prognosis in children: A retrospective cohort study by Ana Lucía Guzmán, Isabella Villamil, Sofía Martínez-Betancur, Oriana Arias-Valderrama, Jacobo Triviño-Arias, Jessica Largo, Viviana Lotero, Alexis Franco, Ximena Castro, Pamela Rodríguez, Luz Angela Urcuqui, Diego Medina, Manuela Olaya

“…They can be either primary, associated with genetic defects, or secondary, linked to external factors such as hemato-oncological conditions. …”
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Innate Immune Recognition of Mycobacterium tuberculosis by Johanneke Kleinnijenhuis, Marije Oosting, Leo A. B. Joosten, Mihai G. Netea, Reinout Van Crevel

“…Human epidemiological studies revealed that genetic variation in genes encoding for PRRs and downstream signaling products influence disease susceptibility, severity, and outcome. …”
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Langerhans Cell Histiocytosis of the Thyroid with Multiple Cervical Lymph Node Involvement Accompanying Metastatic Thyroid Papillary Carcinoma by A. Bahar Ceyran, Serkan Şenol, Barış Bayraktar, Şeyma Özkanlı, Z. Leyla Cinel, Abdullah Aydın

“…Although the etiology is unknown, genetic components may be linked to the disease. It is also associated with a family history of thyroid disease. …”
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TONGUE—A NEWER BIOMETRIC: An Observational Study by Vishnu Rajendran, Arul Jothi Murugan, Anuradha Ganesan

“…Conclusion: Considering the uniqueness, genetic independence, and simple procedure, tongue print can be considered biometric identification along with other forensic identification techniques.…”
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Utilizing FRET-based Biosensors to Measure Cellular Phosphate Levels in Mycorrhizal Roots of Brachypodium distachyon by Shiqi Zhang, Lucas Jurgensen, Maria Harrison

“…With the evolution of quantitative imaging with confocal microscopy, particularly the use of genetically encoded fluorescent sensors, live imaging of intracellular Pi concentrations is now achievable. …”
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Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity by Dyah Ika Krisnawati, Yung-Ching Liu, Yuarn-Jang Lee, Yun-Ting Wang, Chia-Ling Chen, Po-Chun Tseng, Ting-Jing Shen, Chiou-Feng Lin

“…Patients with adult-onset immunodeficiency who suffer from recurrent infections with microbes, particularly nontuberculous mycobacteria (NTM), commonly display genetic defects in IFN-γ signaling as well as the generation of anti-IFN-γ autoantibodies (autoAbs). …”
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Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside by Rajeshwari D. Koilkonda, John Guy

“…Additional mitochondrial and/or nuclear genetic factors may modulate the phenotypic expression of LHON. …”
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Role of hyperhomocysteinemia in atherosclerosis: from bench to bedside by Wende Tian, Jianqing Ju, Baoyi Guan, Tongxin Wang, Jiqian Zhang, Luxia Song, Hao Xu

“…Background Atherosclerosis is a leading cause of global mortality, driven by complex interactions between genetic, metabolic, and environmental factors. Among these, hyperhomocysteinemia (HHcy) has emerged as a significant and modifiable risk factor, contributing to endothelial dysfunction, oxidative stress, and vascular inflammation. …”
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Nutrition and Helicobacter pylori: Host Diet and Nutritional Immunity Influence Bacterial Virulence and Disease Outcome by Kathryn P. Haley, Jennifer A. Gaddy

“…Research aimed at elucidating determinants that mediate disease progression has revealed genetic differences in both humans and H. pylori which increase the risk for developing gastric cancer. …”
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Robust pareto multiobjective optimum design of FG-Beam under moving mass by Moein Abdollah-Salimi, Nader Nariman-Zadeh, Reza Ansari

“…In addition to the means, the variance of the mentioned cost functions was considered to obtain robust behaviour in an uncertain space of parameters. By using a genetic algorithm, a fraction of constituents and an index of volume fraction (design variables) were selected so that objective functions were optimized. …”
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Synopsis of colorectal cancer: prevalence, symptoms, screening, staging, risk factors, and treatment by Gehan F. Balata, Hany N. Azzam

“…Factors that increase the risk of developing colorectal cancer include exposure to chemicals, chronic inflammatory bowel disease, obesity, smoking, family history, genetic mutations, and specific diets. Diets high in fat, consumption of too much iron, sugary beverages, and meals with high sugar content can elevate the risk of CRC, whereas incorporating whole grains, fiber, calcium, vitamin D, dairy products, vegetables, fruits, and green tea into your diet can lower the risk. …”
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Kidney Diseases Classification using Hybrid Transfer-Learning DenseNet201-Based and Random Forest Classifier by Abdalbasit Mohammed Qadir, Dana Faiq Abd

“…There are several disease kinds in global populations that may be related to human lifestyles, social, genetic, economic, and other factors related to the nature of the country they live in. …”
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Prolegomena to the Digital Legal History by S. V. Lonskaya

“…In the article, based on formal-logical, comparative, and historical-genetic methods of cognition, the author presents their own view on the foundations of an interdisciplinary scientific field — digital legal history: its scientific status, subject, sources, goals, tasks, and methodology. …”
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Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer by Daniela Trisciuoglio, Marta Di Martile, Donatella Del Bufalo

“…In this context, different hematological and solid tumors are characterized by deregulation of the protein acetylation pattern as a result of genetic or epigenetic changes. The imbalance between acetylation and deacetylation of histone or nonhistone proteins is also involved in the modulation of the self-renewal and differentiation ability of stem cells, including cancer stem cells. …”
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