Strain-specific effects of Akkermansia muciniphila on the regulation of intestinal barrier by Yang Liu, Qing Liu, Chengcheng Zhang, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai

“…This study confirmed the different effects of A. muciniphila strains on gut barrier modulation and provided molecular and genetic targets for the screening of A. muciniphila strains with superior protection against gut barrier dysfunction.…”
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Biomarkers as Key Contributors in Treating Malignant Melanoma Metastases by Camila Ferreira de Souza, Alice Santana Morais, Miriam Galvonas Jasiulionis

“…Fortunately, there are now evidences sustaining the importance of genetic, epigenetic, and metabolomic alterations as biomarkers for classification, staging, and better management of melanoma patients. …”
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The putative role of immune-inflammatory mechanisms in nociplastic pain pathways: a narrative review by Mariateresa Giglio, Alberto Corriero, Angela Preziosa, Giustino Varrassi, Filomena Puntillo

“…The challenge for the future will be to identify the exact role of inflammation and immunity, the cause of this activation, and its link to other pathogenetic factors of nociplastic pain, such as diet or microbiota alteration, social and phycological factors, together with a genetic and epigenetic predisposition.…”
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The Neuropathology of Autism by Gene J. Blatt

“…The etiologies are unknown and they are genetically complex. There may be epigenetic effects, environmental influences, and other factors that contribute to the mechanisms and affected neural pathway(s). …”
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Exercise-induced extracellular vesicles in reprogramming energy metabolism in cancer by Marju Puurand, Alicia Llorente, Alicia Llorente, Alicia Llorente, Aija Linē, Tuuli Kaambre

“…Cancer is caused by complex interactions between genetic, environmental, and lifestyle factors, making prevention strategies, including exercise, a promising avenue for intervention. …”
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Autoimmune hepatitis: new in diagnostics, a pathogenesis and treatment by Ye. N. Shirokova, K. V. Ivashkin, V. T. Ivashkin

“…AIH is a chronic inflammatory liver disease which is characterized by destruction of terminal plate by mononuclear infiltrate (interface hepatitis) according to histological investigation, hypergammaglobulinemia and production of autoantibodies. Genetic risk factors of AIH development is the presence of DRB1*0301 and DRB1*0401 alleles. …”
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Alpha-Fetoprotein and Novel Tumor Biomarkers as Predictors of Hepatocellular Carcinoma Recurrence after Surgery: A Brilliant Star Raises Again by Quirino Lai, Fabio Melandro, Rafael S. Pinheiro, Andrea Donfrancesco, Bashir A. Fadel, Giovanni B. Levi Sandri, Massimo Rossi, Pasquale B. Berloco, Fabrizio M. Frattaroli

“…The development of a new predictive model combining radiological and biological features based on biological markers is strongly required. New genetic markers are continuously discovered, but they are not already fully available in the clinical practice.…”
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Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation by Mathias Guayasamin, Lewis R Depaauw-Holt, Ifeoluwa I Adedipe, Ossama Ghenissa, Juliette Vaugeois, Manon Duquenne, Benjamin Rogers, Jade Latraverse-Arquilla, Sarah Peyrard, Anthony Bosson, Ciaran Murphy-Royal

“…These behavioural changes were associated with impaired synaptic plasticity, increased neural excitability, and astrocyte hypofunction. Genetic perturbation of amygdala astrocyte function by either reducing astrocyte calcium activity or reducing astrocyte network function was sufficient to replicate cellular, synaptic, and fear memory generalisation associated with early-life stress. …”
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A New Method for the Calibration of Site-Related Response Spectra by Xin Han, Shun Yang, Jingshan Bo, Chaoyu Chang, Mei Guo, Yimeng Cai

“…Accordingly, the best fitting function for each period band is determined. Combined with a genetic algorithm, the control parameters of the seismic acceleration response spectrum are calibrated according to the determined new design spectral shape. …”
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The Impact of Interferon Lambda 3 Gene Polymorphism on Natural Course and Treatment of Hepatitis C by F. Bellanti, G. Vendemiale, E. Altomare, G. Serviddio

“…Host genetic factors may predict the outcome and treatment response in hepatitis C virus (HCV) infection. …”
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Motor-Skill Learning Is Dependent on Astrocytic Activity by Ragunathan Padmashri, Anand Suresh, Michael D. Boska, Anna Dunaevsky

“…To test the hypothesis that astrocytic activity is necessary for motor-skill learning, we perturbed astrocytic function using pharmacological and genetic approaches. We find that perturbation of astrocytes either by selectively attenuating IP3R2 mediated astrocyte Ca2+ signaling or using an astrocyte specific metabolic inhibitor fluorocitrate (FC) results in impaired motor-skill learning of a forelimb reaching-task in mice. …”
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The different faces of GATA2 deficiency: implications for therapy and surveillance by Luca Vinci, Brigitte Strahm, Carsten Speckmann, Carsten Speckmann, Miriam Erlacher, Miriam Erlacher

“…GATA2 deficiency is one of the most common genetic predispositions to pediatric myelodysplastic syndrome (MDS) in children and adolescents. …”
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Cost-Efficient LEO Navigation Augmentation Constellation Design under a Constrained Deployment Approach by Jing Ren, Dan Sun, Deng Pan, Mingtao Li, Jianhua Zheng

“…They are solved by the genetic algorithm and differential evolution algorithm, and both Walker and Flower constellations are adopted. …”
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Mathematical analysis and modeling of DNA segregation mechanisms by Bashar Ibrahim

“…The precise regulation of cell life division is indispensable to the reliable inheritance of genetic material, i.e. DNA, in successive generations of cells. …”
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The corpus callosum in people with congenital adrenal hyperplasia (CAH) by Eileen Luders, Debra Spencer, Caitlin Dale, Ieuan A. Hughes, Ajay Thankamony, Umasuthan Srirangalingam, Helena Gleeson, Helen Simpson, Melissa Hines, Florian Kurth

“…Abstract Congenital Adrenal Hyperplasia (CAH) is a group of genetic disorders that affect the adrenal glands. …”
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Comprehensive Insights into Monkeypox (mpox): Recent Advances in Epidemiology, Diagnostic Approaches and Therapeutic Strategies by Suresh Kumar, Dhanyashri Guruparan, Kalimuthu Karuppanan, K. J. Senthil Kumar

“…Key findings include advancements in understanding the virus’s molecular mechanisms, which highlight its genetic adaptability and potential for zoonotic spillover. …”
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A new species of Hemiphyllodactylus (Squamata, Gekkonidae) from western Yunnan, China by Hongxin Zhou, Xiaohan Wang, Liangwei Cui, Dongru Zhang, Ziqi Shen, Xiuyan Li, Shuo Liu, Dingqi Rao

“…The new species can be distinguished from its congeners by a significant genetic divergence of greater than 4.8% in the mitochondrial ND2 gene and a combination of the following characters: maximum SVL of 38.5 mm; 10 or 11 chin scales; enlarged postmentals; 6 circumnasal scales; 2 or 3 internasal scales; 8 or 9 supralabial scales; 8 or 9 infralabial scales; 15 or 16 dorsal scales; 9 ventral scales; a manual lamellar formula of 3-4-4-4 and a pedal lamellar formula of 3(4)-4-4-4; 26–28 precloacal and femoral pore-bearing scales contiguous in males; 1–3 cloacal spur on each side; a dark postorbital stripe extending to at least base of neck; dorsolateral light–colored spots on trunk present; dark ventrolateral stripe on trunk present; dark dorsal transverse blotches present; and a dark and brown postsacral mark bearing anteriorly projecting arms.…”
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Impaired Adipose Tissue Expandability and Lipogenic Capacities as Ones of the Main Causes of Metabolic Disorders by Isabel Moreno-Indias, Francisco José Tinahones

“…We proposed that the failure of adipose tissue is initiated by the difficulty of this tissue to increase its cellularity due to excess in fat contribution, owing to genetic or environmental factors. Nevertheless, why the adipose tissue reduces its capacity to make new adipocytes via mesenchymal cells of the stroma has not yet been elucidated. …”
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Optimizing cut order planning: A comparative study of heuristics, metaheuristics, and MILP algorithms by Sharif Al-Mahmud, Jose Alejandro Cano, Emiro Antonio Campo, Stephan Weyers

“…Modifications to existing heuristics, combined with tournament selection in genetic algorithms (GA), improve solution quality and efficiency. …”
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GRAY CORRELATION ANALYSIS OF SURFACE INTEGRITY OF ULTRASONIC-ASSISTED ROLLING GCR15 BEARING STEEL by LEI Jun, SU YongXiang, XU QingJun

“…The ultrasonic-assisted rolling test was used to combine the gray theory,response surface method and genetic algorithm to ultrasonically assisted rolling GCr15 bearing steel. …”
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