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10921
STUDY ON ENERGY ABSORPTION CHARACTERISTICS OF CIRCULAR TUBE WITH RECTANGULAR GROOVE BASED ON REGRESSION ANALYSIS
Published 2024-04-01“…Finally, the energy absorption performance index was introduced and the structure of the circular tube was optimized by genetic algorithm. The optimization results show that when the diameter and the groove end distance are the smallest. the wall ess and the groove width are the largest, and the groove depth is the shallowest, the circular tube has the best energy absorption performance in the range of research.…”
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10922
Computational studies of some benzothiazinone-pepirazine derivatives and lipase b inhibitor for mycobacterium tuberculosis
Published 2020-10-01“…The compound structures were drawn with the aid of chemdraw 3D Pro 12.1.0V and optimized was employed using DFT method applying B3LYP with the 6-31G? basis set. Genetic Function Approximation (GFA) was employed to form five models. …”
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10923
Bacteria as Precision Tools for Cancer Therapy
Published 2025-01-01“…ABSTRACT The discovery at the end of the 20th century of genes that induce cell death revolutionised the biocontaintment of genetically manipulated bacteria for environmental or agricultural applications. …”
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10924
Genomic landscape and comparative analysis of tissue and liquid-based NGS in Taiwanese anaplastic thyroid carcinoma
Published 2025-01-01“…This study analyzed ATC samples using tissue-based NGS, liquid-based NGS, or both platforms. Genetic alterations showed highly heterogeneity, including mutations in RAS/RAF/MEK/ERK, PI3K/AKT/mTOR, cell cycle regulation, other receptor tyrosine kinases, DNA damage response, mismatch repair, and chromatin remodeling. …”
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10925
Targeting Histone Deacetylases: A Novel Approach in Parkinson’s Disease
Published 2015-01-01“…Although the exact underlying mechanisms leading to neural cell death in this disease remains unknown, the genetic causes are often established. Indeed, it is becoming increasingly evident that chromatin acetylation status can be impaired during the neurological disease conditions. …”
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10926
Targeting Myeloid-Derived Suppressor Cells Is a Novel Strategy for Anti-Psoriasis Therapy
Published 2020-01-01“…Psoriasis is a common immune-mediated, chronic inflammatory genetic-related disease that affects patients’ quality of life. …”
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10927
Research progress on platelets in glioma
Published 2025-01-01“…TEPs can be used to obtain genetic information about gliomas, which is helpful for early diagnosis and monitoring of therapeutic effects. …”
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10928
The Transcriptional Network Structure of a Myeloid Cell: A Computational Approach
Published 2017-01-01“…Understanding the general principles underlying genetic regulation in eukaryotes is an incomplete and challenging endeavor. …”
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10929
Practice of an improved many-objective route optimization algorithm in a multimodal transportation case under uncertain demand
Published 2025-01-01“…In this paper, we develop, for the first time, a many-objective multimodal transportation route optimization (MTRO) model that simultaneously considers economic cost, carbon emission cost, time cost, and customer satisfaction, and we solve it via the nondominated sorting genetic algorithm version III (NSGA-III). Second, to further improve the convergence performance, we introduce a fuzzy decision variable framework to improve the NSGA-III algorithm. …”
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10930
Accelerated photonic design of coolhouse film for photosynthesis via machine learning
Published 2025-02-01“…Here, using a synergistic genetic algorithm and machine learning, we propose and demonstrate a coolhouse film that regulates temperature and water for photosynthesis without requiring additional energy or water. …”
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10931
Short tandem repeats delineate gene bodies across eukaryotes
Published 2024-12-01“…Abstract Short tandem repeats (STRs) have emerged as important and hypermutable sites where genetic variation correlates with gene expression in plant and animal systems. …”
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10932
The Node Arrangement Methodology of Wireless Sensor Networks for Long-Span Bridge Health Monitoring
Published 2013-10-01“…Subsequently, the node arrangement is divided into two phases of sensor node arrangement and relay node arrangement. An improved general genetic algorithm is proposed to configure sensor nodes, and a nonuniform node arrangement method is developed to distribute relay nodes. …”
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10933
SDF-1/CXCR4 Signaling Maintains Stemness Signature in Mouse Neural Stem/Progenitor Cells
Published 2017-01-01“…Finally, we demonstrated that the expression of achaete-scute homolog 1 (Ascl1), a proneural gene, and p27, an antiproliferative gene, were significantly increased after genetic elimination of SDF-1 alleles. Our results support that the loss of functional SDF-1/CXCR4 signaling pathway in NSCs/NPCs induces exit of cell cycle and promotes premature neural differentiation.…”
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10934
Factors Affecting Isoflavone Content in Soybean Seeds Grown in Thailand
Published 2013-01-01“…Isoflavone content in soybean seeds grown in Thailand depends on multiple genetic and environmental factors. Some varieties (Nakhon Sawan 1 and Sukhothai 1) exhibited moderately high isoflavone content regardless of sowing date. …”
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10935
Autophagic flux modulates tumor heterogeneity and lineage plasticity in SCLC
Published 2025-01-01“…Autophagy, a conserved cellular process, is implicated in many cancers, but its role in SCLC remains unclear.MethodsUsing a genetically engineered mouse model (Rb1fl/fl; Trp53fl/fl; GFP-LC3-RFP-LC3△G), we tracked autophagic flux in vivo to investigate its effects on SCLC biology. …”
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10936
Population-level shape variation and otolith asymmetry in Diplodus annularis
Published 2025-01-01“…These findings underscore the sensitivity of GMM in detecting even subtle morphological differences, making it a powerful tool for studying environmental and genetic influences on marine species.…”
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10937
Histological demonstration of gonad development in the banana shrimp, Fenneropenaeus merguiensis
Published 2025-01-01“…The genetic diversity of the banana shrimp Fenneropenaeus merguiensis is at risk because of over-harvesting, which consequently reduces food security. …”
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10938
A novel dynamic vibration absorber for vibration control of piping systems under multi-frequency harmonic excitations
Published 2025-01-01“…When there is a notable difference in the intensities of the multi-frequency vibration line spectra, a genetic algorithm is utilized to optimize the mass allocation of the resonant units. …”
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10939
Executioner caspases degrade essential mediators of pathogen-host interactions to inhibit growth of intracellular Listeria monocytogenes
Published 2025-01-01“…Here, by means of chemical and genetical modifications, we show that the executioner caspases-3 and -7 efficiently inhibit growth of intracellular Listeria monocytogenes in host cells. …”
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10940
3′ Splice Site Sequences of Spinal Muscular Atrophy Related SMN2 Pre-mRNA Include Enhancers for Nearby Exons
Published 2014-01-01“…Spinal muscular atrophy (SMA) is a human genetic disease which occurs because of the deletion or mutation of SMN1 gene. …”
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