Modern methods of studying of human gastro-intestinal microflora by Ye. A. Poluektova, O. S. Lyashenko, O. S. Shifrin, A. A. Sheptulin, V. T. Ivashkin

“…However, during the last decade modern methods of diagnostics which allow to investigate structure and functions of microorganisms at a genetic level, even at the presence of single bacterial cell in a sample.Conclusion. …”
Get full text

Interleukin-6 “Trans-Signaling” and Ischemic Vascular Disease: The Important Role of Soluble gp130 by Mario Luca Morieri, Angelina Passaro, Giovanni Zuliani

“…Interleukine-6 (IL-6) is a multifunctional cytokine involved both in the beneficial acute inflammatory response and in the detrimental chronic low-grade systemic inflammation. Large genetic human studies, using Mendelian randomization approaches, have clearly showed that IL-6 pathway is causally involved in the onset of myocardial infarction. …”
Get full text

Targeting protein-protein interactions in drug discovery: Modulators approved or in clinical trials for cancer treatment by Cristina Camps-Fajol, Debora Cavero, Jordi Minguillón, Jordi Surrallés

“…Despite the development of PPI modulators is challenging, advances in the genetic, proteomic and computational level have facilitated their discovery and optimization. …”
Get full text

More food, but less land and water for nature: Why agricultural productivity gains did not materialize by Chris Seijger, Anton Urfels, Maria Christoforidou, Petra Hellegers, Gerlo Borghuis, Simon Langan, Gerardo van Halsema

“…Solutions to veer off this path include reducing food demand (including dietary change), stabilising rainfed agriculture and broadening the crop genetic resources base.…”
Get full text

Late-Onset Isolated Corticotrope Deficiency in a Woman with Down Syndrome by Ibtissem Oueslati, Marwa Ben Jemaa, Meriem Yazidi, Fatma Chaker, Melika Chihaoui

“…Magnetic resonance imaging scan revealed a partially empty sella turcica. Genetic analysis showed no mutations and no copy number variants of the TBX19 and NFKB2 genes. …”
Get full text

A novel SEPT12 mutation, T96I, is associated with sperm head and annulus defects by Kuan-Ru Chen, Han-Yu Wang, Han-Yu Wang, Yung-Che Kuo, Yu-Chih Lo, Pao-Lin Kuo, Pao-Lin Kuo, Pao-Lin Kuo

“…Infertility affects around 8%–12% of reproductive-aged couples and is a major health concern. Both genetic and environmental factors influence male infertility. …”
Get full text

Pathogenesis of Myeloproliferative Neoplasms: Role and Mechanisms of Chronic Inflammation by Sylvie Hermouet, Edith Bigot-Corbel, Betty Gardie

“…The aim of this paper is to review the different aspects of inflammation in MPNs, the molecular mechanisms involved, the role of specific genetic defects, and the evidence that increased production of certain cytokines depends or not on MPN-associated mutations, and to discuss possible nongenetic causes of inflammation.…”
Get full text

NKAPL facilitates transcription pause-release and bridges elongation to initiation during meiosis exit by Zhenlong Kang, Chen Xu, Shuai Lu, Jie Gong, Ruoyu Yan, Gan Luo, Yuanyuan Wang, Qing He, Yifei Wu, Yitong Yan, Baomei Qian, Shenglin Han, Zhiwen Bu, Jinwen Zhang, Xian Xia, Liang Chen, Zhibin Hu, Mingyan Lin, Zheng Sun, Yayun Gu, Lan Ye

“…NKAPL depletion prolongs Pol II pauses and stalls the SOX30/HDAC3 transcription initiation complex on the chromatin. Genetic variants in NKAPL are associated with azoospermia in humans, while mice carrying an NKAPL frameshift mutation (M349fs) show defective meiotic exit and transcriptomic changes similar to NKAPL depletion. …”
Get full text

Echocardiography indicators in patients with atherosclerosis of peripheral arteries of the lower extremities dependent on T(–786)C polymorphism of the endothelial nitric oxide synt... by V.I. Tseluyko, O.D. Yarova

“…Doppler ultrasound examination of the lower extremities and carotid arteries (CA), transthoracic echocardiography (EchoCG), ECG Holter monitoring and genetic analysis using polymerase chain reaction were performed. …”
Get full text

CD14loCD301b+ macrophages gathering as a proangiogenic marker in adipose tissues by Yibing Lv, Yidan Zheng, Shanshan Su, Junyi Xiao, Jie Yang, Lingyun Xiong, Yanyan Guo, Xiaoqi Zhou, Nengqiang Guo, Ping Lei

Get full text

DNA PROTECTIVE ACTIVITY OF Artemisia spp HAIRY ROOT EXTRACTS by Duplij V., Afanasieva K., Chopei M., Matvieieva N. A.

Get full text

Network analysis combined with genome-wide association study helps identification of genes related to amino acid contents in soybean by Kyujung Van, Sungwoo Lee, M. A. Rouf Mian, Leah K. McHale

“…Among those approaches, the GWAS network analysis we implemented takes advantage of the relationships between specific AAs to identify the genetic control of AA profile. Results For Approach I, GWAS were performed for the content of 24 single AAs under all environments combined. …”
Get full text

POVEIKIS IR ATSAKAS BIOLOGINIUOSE VYKSMUOSE by Jonas Rubikas

“…Key words: affect, response, probability, conditionality, genetic regulation. …”
Get full text

Identification and characterization of Serratia nematophila and Acinetobacter guillouiae from putrid-skin disease lesions in farmed Chinese spiny frog (Quasipaa spinosa) by Ling Guo, Xiyu Jin, Dan Yang, Li Wei, Jie Chen, Zhihua Lin, Li Ma

“…Our findings offer a scientific foundation for the accurate diagnosis and control of putrid-skin disease in frogs, contributing to the preservation of Q. spinosa genetic resources.…”
Get full text

Plastid genome comparison and phylogenetic analyses of the Chinese group of medicinal species and related taxa within Asparagus genus by Pingxuan Xie, Tinglu Wang, Jiawei Tan, Linyuan Fan, Changkun Liu, Hanjing Yan

“…Overall, this study offers a wealth of informative genetic resources pertinent to Asparagus, thereby enhancing our understanding of its evolution and laying a foundation for species identification, assessment of genetic population diversity, as well as the exploration and conservation of germplasm resources.…”
Get full text

Vaginal colonization, vertical transmission rate, antimicrobial susceptibility profile, and associated factors of potential neonatal pathogens among pregnant women at public health... by Getnet Shimeles, Getnet Shimeles, Alemu Gedefie, Hilina Motbainor, Chalachew Genet, Chalachew Genet

Get full text

Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior by Qi Chen, Jun Ma, Ruipeng Wu, Yingting Wang, Xiaoxin Ma, Xiaolei Zheng, Hui Jin

Get full text

POVEIKIS IR ATSAKAS BIOLOGINIUOSE VYKSMUOSE by Jonas Rubikas

“…Key words: affect, response, probability, conditionality, genetic regulation. …”
Get full text

Interplay between BMI, neutrophil, triglyceride and uric acid: a case-control study and bidirectional multivariate mendelian randomization analysis by Haoyuan Lyu, Na Fan, Hao Wen, Xin Zhang, Herong Mao, Qinglai Bian, Jiaxu Chen

“…Within this framework, and multivariable Mendelian randomization(MVMR) was applied to explore the linkage between multiple genetic variants and complex traits. Results The study primarily focused on UA, employing genetic variation as a natural tool to assess the causal impact of various factors on UA. …”
Get full text

Preterm preeclampsia screening and prevention: a comprehensive approach to implementation in a real-world setting by Stefania Ronzoni, Shamim Rashid, Aimee Santoro, Elad Mei-Dan, Jon Barrett, Nanette Okun, Tianhua Huang

Get full text