The effect of feed additive ethoxyquin on tilapia growth performance and potential secondary hazard to consumers by Shanjun Chen, Chong Wang, Yanan Liu, Zhigang Zhou, Linglin Fu, Yanbo Wang

“…In this work, EQ was applied to tilapia fed with either high-fat or low-fat feed, and the changes in growth performance and intestinal barrier integrality of genetically improved farmed tilapia was observed. Additionally, the microbiota in the intestinal content and flesh was analyzed by 16S rDNA sequencing, and the flesh metabolites was measured by LC-MS/MS untargeted metabolomics. …”
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Maternally Inherited Diabetes Mellitus Associated with a Novel m.15897G>A Mutation in Mitochondrial tRNAThr Gene by Ke Li, Lijun Wu, Jianjiang Liu, Wei Lin, Qiang Qi, Tianlan Zhao

“…We report here the clinical, genetic, and molecular characteristics of type 2 diabetes in a Chinese family. …”
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Chromosome-level genome assembly and annotation of the gynogenetic large-scale loach (Paramisgurnus dabryanus) by Lei Zhang, Wanting Zhang, Yingyin Cheng, Yutong Fang, Xin Guan, Ao Gong, Yanxin Jiang, You Duan, Lei Huang, Waqar Younas, Yaping Wang, Mijuan Shi, Xiao-Qin Xia

“…Currently, molecular mechanism studies related to some aspects such as sex determination, toxicology, feed nutrition, growth and genetic evolution have been conducted. However, the lack of a high-quality reference genome has hindered further research. …”
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DETERMINATION OF INFECTIOUS DISEASESBY POLYMERASE CHAIN REACTION by Zuneera Akram

“…Extensive application of science has provided high sensitivity and ease, with which PCR can identify known genetic sequences. A variety of molecular experiments are focused mainly on what has been described, including in real-time PCRs, multi-plex PCRs, LAMP-PCRs and digital PCRs. …”
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Optimal Road Toll Design from the Perspective of Sustainable Development by Lin Cheng, Fei Han

“…The upper level problem is the network toll design problem to maximize the SD-index from the viewpoint of traffic managers, and the lower level problem is to depict travelers’ route choice behavior under a certain road toll scheme. Finally, a combined genetic algorithm and gradient projection algorithm (GA-GP) is used to solve the bilevel model, in which the GP algorithm solves the traffic assignment problem with road toll scheme in the lower level. …”
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Brown fat thermogenesis and branched-chain amino acids in metabolic disease by Zachary Brown, Takeshi Yoneshiro

“…Recent advances in metabolomics, advanced imaging techniques, and genetic analyses over the past decade have enabled newfound insights into the mechanism of BCAA metabolic dysregulation across a variety of peripheral tissues and its impact on metabolic disease, suggesting a key role for brown adipose tissue (BAT) in determining BCAA metabolic homeostasis. …”
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Neurofibromatosis Type 1 Complicated by Atypical Coarctation of the Thoracic Aorta by Masato Kimura, Shuhei Kakizaki, Kengo Kawano, Shinichi Sato, Shigeo Kure

“…Neurofibromatosis type 1 (NF1) is a relatively common autosomal dominant genetic disorder with a prevalence of 1 in 3,000 (0.03%) at birth. …”
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Tribological Behavior and Analysis on Surface Roughness of CNC Milled Dual Heat Treated Al6061 Composites by A. Bovas Herbert Bejaxhin, G.M. Balamurugan, S.M. Sivagami, K. Ramkumar, V. Vijayan, S. Rajkumar

“…The influencing factors are identified by the Taguchi, genetic algorithm (GA), and Artificial Neural Network (ANN) techniques and compared within it. …”
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Microbes from Peat Swamp Forest — The Hidden Reservoir for Secondary Metabolites? by Kuan-Shion Ong, Vengadesh Letchumanan, Jodi Woan-Fei Law, Catherine M. Yule, Sui-Mae Lee

“…They are known as multifaceted organisms not only because of their genetic content, but also due to their positive interactions with the environment along with a plethora of organisms including plants and animals. …”
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Application of Harmony Search to Design Storm Estimation from Probability Distribution Models by Sukmin Yoon, Changsam Jeong, Taesam Lee

“…The HS is compared to the genetic algorithm (GA) and ML via simulation and case study. …”
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Dislocation density-based simulation of pre-mixed jet effects on residual stress and cell size in 18CrNiMo7-6 alloy steel by MingHao Zhao, HaiYang Hou, FeiHu Ren, Chunsheng Lu, JianWei Zhang, BingBing Wang

“…The model employs a dislocation density-based constitutive relationship, with parameters optimized via a genetic algorithm. A fully coupled stress integration algorithm ensures the numerical stability. …”
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Zebrafish Thrombocytes: Functions and Origins by Gauri Khandekar, Seongcheol Kim, Pudur Jagadeeswaran

“…Keeping this in mind we introduced zebrafish, a vertebrate genetic model to study platelet function. We characterized zebrafish thrombocytes and established functional assays study not only their hemostatic function but to also their production. …”
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Neurofibromatosis type 1 or Von Recklinghausen's disease. A case report by Marisleidy Denis Rodríguez, Miguel Alejandro Pulido Gutiérrez, Thaimi Conde Cueto, Luis Omar López Hurtado

“…Neurofibromatosis type I or Von Recklinghausen's disease is one of the genetic diseases that affect the nervous system, named for its common embryonic origin. …”
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Protective Immunity against SARS Subunit Vaccine Candidates Based on Spike Protein: Lessons for Coronavirus Vaccine Development by Atin Khalaj-Hedayati

“…By considering the high genetic similarity between SARS-CoV and SARS-CoV-2, here, protective immunity against SARS-CoV spike subunit vaccine candidates in animal models has been reviewed to gain advances that can facilitate coronavirus vaccine development in the near future.…”
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Optimization of Job Scheduling in the Cloud Computing Environment Using the Fuzzy Particle Swarm Optimization Algorithm by Shabnam Gharaeian, Khosrow Amirizadeh

“…Results show that the suggested optimization method can effectively improve criteria like makespan once compared with results of algorithms without optimization, like Ron-robin, and even in comparison to other optimization algorithms, like genetic algorithm.…”
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Firefly Optimization Algorithm for the Prediction of Uplift due to High-Pressure Jet Grouting by Wukui Dai, Li Liang, Bingji Zhang

“…As a result of the global optimization capacity and by comparison with the genetic algorithm, the FOA has a greater advantage in terms of effectiveness and precision. …”
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Impact and compensation of sample clock offset in I-CFDMA uplink by Dan DING, Nai-ping CHENG, Yu-rong LIAO

“…To achieve the sample clock synchronization in the interleaved code and frequency division multiple access(I-CFDMA)uplink,the I-CFDMA uplink model was established,and the disturbance of the sample clock offset(SCO)on the system model was discussed,in addition,the signal time shift,phase rotation,multi-user interference(MUI)and inter-carrier interference(ICI)caused by SCO were analyzed quantitatively.On this basis,a compensation method of multi-user SCO was proposed.For one thing,the relevant metric function was modified considering the SCO of each user; for another thing,a multi-user detection(MUD)algorithm based on harmony search was proposed.This algorithm has a higher efficiency than the commonly-used genetic algorithm(GA),as well as a performance approximate to that of optimal detection without SCO but with <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML"> <mfrac> <mn>1</mn> <mrow> <mn>64</mn></mrow> </mfrac> </math></inline-formula> computational burden.The computer simulation results validate the conclusions obtained.…”
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Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice by Wen Yin, Heng Xu, Zhonghao Bai, Yue Wu, Yan Zhang, Rui Liu, Zhangzhao Wang, Bei Zhang, Jing Shen, Hao Zhang, Xin Chen, Danting Ma, Xiaofeng Shi, Lihui Yan, Chang Zhang, Hualiang Jiang, Kaixian Chen, Dean Guo, Wenyan Niu, Huiyong Yin, Weiping J. Zhang, Cheng Luo, Xiangyang Xie

“…Here, we show that peroxidase activity of global hepatic peroxiredoxin (PRDX) is significantly decreased in NASH, and palmitic acid (PA) binds to PRDX1 and inhibits its peroxidase activity. Using three genetic models, we demonstrate that hepatic PRDX1 protects against NASH in male mice. …”
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Inflammation in Diabetic Nephropathy by Andy K. H. Lim, Gregory H. Tesch

“…Lastly, we present the latest data on the pathogenic role of the stress-activated protein kinases in diabetic nephropathy, from studies on the p38 mitogen activated protein kinase and the c-Jun amino terminal kinase cell signalling pathways. The genetic and pharmacological approaches which reduce inflammation in diabetic nephropathy have not only enhanced our understanding of the pathophysiology of the disease but shown promise as potential therapeutic strategies.…”
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The Gut Microbiome Profile in Obesity: A Systematic Review by Olga Castaner, Albert Goday, Yong-Moon Park, Seung-Hwan Lee, Faidon Magkos, Sue-Anne Toh Ee Shiow, Helmut Schröder

“…Among the vast quantity of factors attributed to obesity, environmental, dietary, lifestyle, genetic, and others, the microbiome has aroused curiosity, and the scientific community has published many original articles. …”
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