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10761
Analysis of Consumer Behavior Data Based on Deep Neural Network Model
Published 2022-01-01“…In order to improve the accuracy of sample classification and maximize the output function, genetic algorithm is used to optimize the samples. …”
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10762
Bioaccessibility In Vitro of Nutraceuticals from Bark of Selected Salix Species
Published 2014-01-01“…This properties are strongly dependent on extraction system and genetic factors. Regardless of Salix genotypes, the lowest chelating power was found for chemically-extractable compounds. …”
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10763
Biobased Polylactide Nanoparticles as Novel Gene Delivery Nanoplatforms: Can They Be Used for DNA Transport?
Published 2024-04-01“…Gene therapy is a rapidly progressing field with vast prospective for fundamentally treating human diseases such as cancer, damaged tissues, and genetic syndromes. Between various approaches of gene delivery, there is a growing interest in oral administration of DNA as one of the safest and most straightforward methods. …”
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10764
Choice of Unmanipulated T Cell Replete Graft for Haploidentical Stem Cell Transplant and Posttransplant Cyclophosphamide in Hematologic Malignancies in Adults: Peripheral Blood or...
Published 2016-01-01“…However, some issues are still of concern regarding finding a donor like shrinking family sizes in many societies, underrepresentation of the ethnic minorities in the registries, genetic variability for some races, and significant delays in obtaining stem cells after starting the search. …”
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10765
Endothelial calcium firing mediates the extravasation of metastatic tumor cells
Published 2025-02-01“…Summary: Metastatic dissemination is driven by genetic, biochemical, and biophysical cues that favor the distant colonization of organs and the formation of life-threatening secondary tumors. …”
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10766
RIS-assisted terahertz frequency band vehicle network capacity optimization
Published 2023-10-01“…In order to alleviate the spectrum scarcity and capacity limitation of the current wireless system, the terahertz frequency band was introduced and the reconfigurable intelligent surface (RIS) was used for auxiliary communication to construct a downlink vehicle network.Considering the constraints of limited total system power, QoS constraints of cellular mobile users, and randomness constraints of vehicle and user locations, a hybrid optimization model was established for optimal power allocation and optimal deployment of RIS with the aim of maximizing the total rate of vehicle users.Based on the balance method, linear transformation method, and element elimination method, the original NP-hard problem was transformed into a convex optimization problem with complex correlation constraints and multivariate coupling.The inner layer iteration was based on the Lagrange multiplier method to solve the optimal power allocation, and the outer layer iteratively solved the optimal deployment of RIS based on a improved genetic algorithm.The simulation results show that rationally deploying the number and distribution density of RIS nodes based on optimal power allocation can save costs while achieving a higher target total capacity.…”
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10767
Application of Optimized BP Neural Network In Financial Alert System
Published 2022-01-01“…Considering the shortcomings of BP neural network, genetic algorithm is used to optimize the specification. …”
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10768
The role of the early-life gut microbiome in childhood asthma
Published 2025-12-01“…The etiology of asthma is multifactorial, caused by both genetic and environmental factors. In recent years, the role of the early-life gut microbiome in relation to asthma has become apparent, supported by an increasing number of population studies, in vivo research, and intervention trials. …”
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10769
An Indian Case Study on Mitochondrial Neurogastrointestinal Encephalomyopathy
Published 2024-05-01“…Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a unique autosomal recessive disorder characterized by mitochondrial changes resulting from mutations in the TYMP gene, responsible for encoding thymidine phosphorylase. Despite its genetic origin, the study indicates that the manifestation of MNGIE does not strictly adhere to a hereditary pattern. …”
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10770
Single-cell transcriptomes reveal spatiotemporal heat stress response in maize roots
Published 2025-01-01“…We find that cortex size strongly correlated with heat tolerance that is experimentally validated by using inbred lines and genetic mutation analysis of one candidate gene in maize, providing potential HS tolerance indicator and targets for crop improvement. …”
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10771
The Endotoxin-Induced Neuroinflammation Model of Parkinson's Disease
Published 2011-01-01“…This model, by itself or together with genetic and toxin-based animal models, provides an important tool to delineate the precise mechanisms of neuroinflammation-mediated dopaminergic neuron loss. …”
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10772
Climate Change Adaptation: New Perspectives for Natural Resource Management and Conservation
Published 2012-03-01“…The rate at which climate is projected to change in coming decades is likely too fast for many species to genetically adapt or to migrate to new suitable areas. …”
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10773
The Need for Development of New HIV-1 Reverse Transcriptase and Integrase Inhibitors in the Aftermath of Antiviral Drug Resistance
Published 2012-01-01“…Due to reasons of both affordability and availability, some reverse transcriptase inhibitors with low genetic barrier are more commonly used in resource-limited settings. …”
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10774
Molecular Prevalence and Identification of Ehrlichia canis and Anaplasma platys from Dogs in Nay Pyi Taw Area, Myanmar
Published 2021-01-01“…In Myanmar, there is limited information concerning tick-borne pathogens, Ehrlichia and Anaplasma spp., as well as genetic characterization of these species. We performed nested PCR for the gltA gene of the genus Ehrlichia spp. and the 16S rRNA gene of the genus Anaplasma spp. with blood samples from 400 apparently healthy dogs in Nay Pyi Taw area. …”
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10775
Meningomielocele e seu manejo na genética pediátrica: uma revisão de tema de seus aspectos biomédicos e psicossociais
Published 2024-12-01“…It can be influenced by genetic and environmental factors. The consumption of folic acid and vitamin B12 has been associated with a reduced risk of congenital malformations, including myelomeningocele. …”
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10776
Multiobjective Optimization of Precision Forging Process Parameters Based on Response Surface Method
Published 2015-01-01“…Nondominated sorting genetic algorithm-II (NSGA-II) was adopted to obtain the Pareto-optimal solutions. …”
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10777
Formulation of the protein synthesis rate with sequence information
Published 2018-03-01“…Translation is a central biological process by which proteins are synthesized from genetic information contained within mRNAs. Here, we investigate the kinetics of translation at the molecular level by a stochastic simulation model. …”
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10778
Chemical catalyst manipulating cancer epigenome and transcription
Published 2025-01-01“…However, the specific consequences of each histone PTM remain largely unclear, primarily due to the lack of methods for selectively and rapidly introducing a desired histone PTM in living cells without genetic engineering. Here, we report the development of a cell-permeable histone acetylation catalyst, BAHA-LANA-PEG-CPP44, which selectively enters leukemia cells, binds to chromatin, and acetylates H2BK120 of endogenous histones in a short reaction time. …”
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10779
Olfactory dysfunction as potential biomarker in neurodegenerative diseases: a narrative review
Published 2025-01-01“…We summarize the most common methods used to measure olfactory function and delve into neuropathological correlations and the alterations in neurotransmitter systems associated with OD in those neurodegenerative diseases, including differences in genetic variants if applicable, and cater to current pitfalls and shortcomings in the research.…”
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10780
Biomechanics in the tumor microenvironment: from biological functions to potential clinical applications
Published 2025-01-01“…Furthermore, the pharmacological or genetic manipulation of mechanical checkpoints, such as PIEZO1, DDR1, YAP/TAZ, and TRPV4, has shown remarkable potential in immune activation and eradication of tumors. …”
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