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10681
Improved Clonal Selection Algorithm Based on Biological Forgetting Mechanism
Published 2020-01-01“…Compared with the existing clonal selection and genetic algorithms, the experiment and time complexity analysis show that the algorithm has good optimization efficiency and stability.…”
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10682
Esophageal adenocarcinoma: risk factors and modern screening strategy
Published 2018-08-01“…Male gender, Caucasian race, obesity and metabolic syndrome, tobacco smoking, and series of genetic markers are considered to be significant EAC risk factors. …”
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10683
HYEI: A New Hybrid Evolutionary Imperialist Competitive Algorithm for Fuzzy Knowledge Discovery
Published 2014-01-01“…In recent years, imperialist competitive algorithm (ICA), genetic algorithm (GA), and hybrid fuzzy classification systems have been successfully and effectively employed for classification tasks of data mining. …”
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10684
A comprehensive allele specific expression resource for the equine transcriptome
Published 2025-01-01“…Within these events, 635 (1.48%) demonstrated ASE, with liver tissue containing the highest proportion. Genetic variants within ASE events were located in histone modified regions 64.2% of the time. …”
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10685
Developmental and Epileptic Encephalopathy: Pathogenesis of Intellectual Disability Beyond Channelopathies
Published 2025-01-01“…What sets DEEs apart is their complex interplay of epilepsy and developmental delay, often driven by genetic factors. These two aspects influence one another but can develop independently, creating diagnostic and therapeutic challenges. …”
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10686
Optimization of high-dimensional expensive multi-objective problems using multi-mode radial basis functions
Published 2025-01-01“…Meanwhile, bi-population based on competitive swarm optimizer and genetic algorithm are applied for better exploration and exploitation in high-dimensional search space. …”
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10687
Caspase-10 Is the Key Initiator Caspase Involved in Tributyltin-Mediated Apoptosis in Human Immune Cells
Published 2012-01-01“…When compared to Fas-ligand control stimulation, the same sequence of events occurs: membrane blebbing, phosphatidylserine externalisation, the activation of the “death-inducing signalling complex,” and the following sequence of cleavage processes. In genetically modified caspase-8-deficient Jurkat cells, the apoptotic effects are only slightly reduced, whereas, in FADD-negative Jurkat cells, the TBT effect is significantly diminished. …”
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10688
Gene-Gene Interaction Analysis for the Accelerated Failure Time Model Using a Unified Model-Based Multifactor Dimensionality Reduction Method
Published 2016-12-01“…Although a large number of genetic variants have been identified to be associated with common diseases through genome-wide association studies, there still exits limitations in explaining the missing heritability. …”
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10689
Optimized Hyper Beamforming of Linear Antenna Arrays Using Collective Animal Behaviour
Published 2013-01-01“…As compared to conventional hyper beamforming of linear antenna array, real coded genetic algorithm (RGA), particle swarm optimization (PSO), and differential evolution (DE) applied to the hyper beam of the same array can achieve reduction in sidelobe level (SLL) and same or less first null beam width (FNBW), keeping the same value of hyperbeam exponent. …”
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10690
Bio particle swarm optimization and reinforcement learning algorithm for path planning of automated guided vehicles in dynamic industrial environments
Published 2025-01-01“…It is compared with Particle Swarm Optimization (PSO), Genetic Algorithm (GA), and Transit Search (TS) algorithms by benchmark functions. …”
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10691
Signature Prediction Modeling in Cytolethal Distending Toxin-Producing Strains
Published 2017-06-01“…It was shown that they could be used as biomarkers for research purposes and clinical diagnosis by polymerase chain reaction, or in vaccine development. cdt genes and several other genetic biomarkers were identified as signature sequences in CDT producer strains. …”
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10692
Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling
Published 2025-01-01“…However, KARs and a plant hormone, strigolactones (SLs), have high resemblance in signal perception and transduction, making it hard to delineate KARs response due to the shortage of chemical-genetic tools. Here, we identify a triazole urea KK181N1 as an inhibitor of the KARs receptor KAI2. …”
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10693
Smaller Fleas: Viruses of Microorganisms
Published 2012-01-01“…These viruses of microorganisms, or VoMs, in fact exist as the world’s most abundant somewhat autonomous genetic entities and include the viruses of domain Bacteria (bacteriophages), the viruses of domain Archaea (archaeal viruses), the viruses of protists, the viruses of microscopic fungi such as yeasts (mycoviruses), and even the viruses of other viruses (satellite viruses). …”
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10694
sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway
Published 2023-01-01“…Genetic factors play an important role in the pathogenesis of systemic lupus erythematosus (SLE), and abnormal Toll-like receptor (TLR) signaling pathways are closely related to the onset of SLE. …”
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10695
Mechanism Analysis and Parameter Optimization of Mega-Sub-Isolation System
Published 2016-01-01“…Considering the number and location of the isolated substructures, a procedure to optimally design the isolator parameters of the mega-sub-isolation system is put forward based on the genetic algorithm with base shear as the optimization objective. …”
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10696
Viral entry mechanisms: the role of molecular simulation in unlocking a key step in viral infections
Published 2025-02-01“…Enveloped viruses are enclosed by a lipid membrane that protects their genetic material and these viruses are linked to various human illnesses, including influenza, and COVID‐19. …”
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10697
Induced Ripening Agents and Their Effect on Fruit Quality of Banana
Published 2019-01-01“…Ripening is a genetically programmed highly coordinated irreversible phenomenon which includes many biochemical changes including tissue softening, pigment changes, aroma and flavour volatile production, reduction in astringency, and many others. …”
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10698
Optimal Integrated Model for Feeder Transit Route Design and Frequency-Setting Problem with Stop Selection
Published 2020-01-01“…As this study explored an NP-hard problem, a two-stage genetic algorithm combining the Dijkstra search method was further developed to yield metaoptimal solutions to the model within an acceptable time. …”
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10699
Outcomes of dietary interventions in the prevention and progression of Parkinson's disease: A literature review
Published 2024-12-01“…Despite extensive research, the exact etiology of PD remains unclear, with both genetic and environmental factors playing significant roles. …”
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10700
A Case of Physically Abused OCD Patient Who Physically Abused Her own Child
Published 2013-07-01“…It was suggested that along with genetic factors various psychosocial factors may play a role in the development of Obsessive Compulsive Disorder (OCD). …”
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