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10521
Physiologic Course of Female Reproductive Function: A Molecular Look into the Prologue of Life
Published 2015-01-01“…The genetic, endocrine, and metabolic mechanisms underlying female reproduction are numerous and sophisticated, displaying complex functional evolution throughout a woman’s lifetime. …”
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10522
Solitary fibular metastasis from lung adenocarcinoma with gene mutation: a case report
Published 2025-01-01“…Imaging revealed bony destruction of the right fibular head, and further investigations with chest CT, PET/C, pathologic biopsy and genetic testing identified a primary lung adenocarcinoma with EGFR exon 19 deletion mutation. …”
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10523
Negative regulation of lymphangiogenesis by Tenascin-C delays the resolution of inflammation
Published 2025-02-01“…We found an inverse correlation between lymphangiogenesis and TNC expression in a mouse lymphedema model. Genetic deletion of Tnc promotes lymphangiogenesis and improves lymphatic drainage function, thereby accelerating the resolution of inflammation. …”
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10524
De l’ojibwa au dakota : pour une analyse transformationnelle des langues amérindiennes
Published 2006-06-01“…Since linguists tried to classify the languages of the New World they were using the same genetical model which lays at the base of the classification of Indo-European languages. …”
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10525
Near telomere-to-telomere assembly of the Tarim pigeon (Columba livia) genome
Published 2024-12-01“…The genome assembly of C. livia lays the foundation for understanding their genetic composition and evolutionary history and contributes to the pigeon breeding industry. …”
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10526
Microbiota and metabolic dysfunction associated with steatotic liver disease
Published 2024-09-01“…Disease progression in metabolic dysfunction-associated steatotic liver disease (MASLD) is driven by multiple mechanisms that act together in genetically predisposed subjects. Amongst others, the gut-liver axis plays a crucial role in the development and progression of MASLD. …”
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10527
Polycystic Ovary Syndrome May Be an Autoimmune Disorder
Published 2016-01-01“…It is a common cause of menstrual irregularities and infertility during reproductive age. Genetic and hormonal factors play crucial role in the pathogenesis of PCOS. …”
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10528
CRISPR/Cas9-Based Protocol for Precise Genome Editing in Induced Pluripotent Stem Cells
Published 2024-12-01“…The advent of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-based genome editing has marked a significant advancement in genetic engineering technology. However, the editing of induced pluripotent stem cells (iPSCs) with CRISPR presents notable challenges in ensuring cell survival and achieving high editing efficiency. …”
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10529
Extracellular Vesicles as Tools for Crossing the Blood–Brain Barrier to Treat Lysosomal Storage Diseases
Published 2025-01-01“…This review highlights the unique properties of EVs, such as their biocompatibility, capacity to cross the blood–brain barrier (BBB), and potential for therapeutic cargo loading, including that of enzymes and genetic material. Current therapies for LSDs, like enzyme replacement therapy (ERT), often fail to address neurological symptoms due to their inability to cross the BBB. …”
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10530
Cardiovascular Disease, Single Nucleotide Polymorphisms; and the Renin Angiotensin System: Is There a MicroRNA Connection?
Published 2010-01-01“…Essential hypertension is a complex disorder, caused by the interplay between many genetic variants, gene-gene interactions, and environmental factors. …”
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10531
Virulence and pathogenicity of group B Streptococcus: Virulence factors and their roles in perinatal infection
Published 2025-12-01“…A detailed exploration of the genetic basis for GBS pathogenicity follows, emphasizing the roles of capsules in pathogenesis and immune evasion. …”
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10532
TLE1 Positive Clear Cell Sarcoma of the Kidney: A Case Report and Review of the Literature
Published 2018-01-01“…The tumor however was double positive for CD99 and TLE1 which made it difficult to discriminate it from the myxoid variant of SS based on histopathological examination and immunophenotype alone, and genetic analysis for SYT gene rearrangement was required to reach a definitive diagnosis. …”
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10533
Anomalous Coronary Artery Origin in a Young Patient with Marfan Syndrome
Published 2017-01-01“…Marfan syndrome is an autosomal dominant genetic disorder that affects connective tissue and is caused by mutations in the fibrillin 1 gene present at chromosome 15. …”
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10534
Cardiovascular Risk Factors after Childhood Cancer Treatment Are Independent of the FTO Gene Polymorphism?
Published 2018-01-01“…The study objective was to assess the prevalence of cardiovascular disease risk factors in patients treated for childhood cancer (N=101) and to determine the involvement of clinical (cancer type and therapy) and/or genetic (FTO gene rs9939609 polymorphism) factors. …”
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10535
The impact of wheat stripe rust in the presence of resistance genes Yr9, Yr10, and Yr15 on gluten proteins: Insights from size-exclusion high-performance liquid chromatography anal...
Published 2025-06-01“…Bread wheat quality is influenced by genetic and environmental effects and their interactions. …”
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10536
Insulin/IGF-I and Related Signaling Pathways Regulate Aging in Nondividing Cells: from Yeast to the Mammalian Brain
Published 2010-01-01“…We will discuss how the “molecular strategy” responsible for life span extension in response to dietary and genetic manipulations appears to be remarkably conserved in various organisms and cells, including neuronal cells in different organisms. …”
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10537
In-the-Field Authentication of Grapevine (Vitis vinifera L.) cv: Albariño Using Chlorotype Discrimination and a Single SNP Interrogation by LAMP
Published 2023-01-01“…This methodology constitutes a valuable tool for cultivar discrimination and can be efficiently implemented in the traceability of valuable grapevine genetic resources.…”
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10538
ENRICHMENT OF MASSIVE SULFIDES FROM THE SEMENOV HYDROTHERMAL CLUSTER (MID-ATLANTIC RIDGE) IN BARITE: A RESULT OF E-MORB INVOLVEMENT AND MAGMATIC CONTRIBUTION
Published 2024-12-01“…The paper reviews and compares the barite findings in hydrothermal fields of the midoceanic ridges. The genetic significance of barite is considered for the Semenov hydrothermal sulfide cluster associated with an oceanic core complex (OCC) at 13°30′ N of the Mid-Atlantic Ridge. …”
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10539
Optimal Design of Double-stage Wheel Hub Reducer System based on Fuzzy Theory
Published 2017-01-01“…Based on the characteristic of genetic algorithms,improving the weight coefficients of the search methods and increasing the optimization searching space,compared with other optimization methods,the result is improved. …”
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10540
Nuclear Power Plant Maintenance Optimization with Heuristic Algorithm
Published 2014-01-01“…The optimal solution of the objective function is estimated with genetic algorithm. The proposed method is applied on probabilistic safety analysis model of the selected safety system of the reference nuclear power plant. …”
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