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10461
The Impact of Embryo Donation Technology on Child Psychological Adjustment and parenting styles: A Comparative Study
Published 2025-01-01“…Furthermore, parenting styles did not significantly differbetween the two groups.Conclusion: The absence of genetic parent-child relationships does not appear to be a dominantfactor influencing the psychological adjustment of children or parenting styles.…”
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10462
High-throughput method characterizes hundreds of previously unknown antibiotic resistance mutations
Published 2025-01-01“…We present a high-throughput technique – Quantitative Mutational Scan sequencing (QMS-seq) – that enables quantitative comparison of which genes are under antibiotic selection and captures how genetic background influences resistance evolution. …”
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10463
Real-Time Pipeline Leak Detection: A Hybrid Deep Learning Approach Using Acoustic Emission Signals
Published 2024-12-01“…The core of the framework combines convolutional neural networks (CNNs) with long short-term memory (LSTM), ensuring a comprehensive examination of both spatial and temporal features of AE signals. A genetic algorithm (GA) optimizes the neural network by isolating the most important features for leak detection. …”
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10464
Sedum alfredii Hance: A cadmium and zinc hyperaccumulating plant
Published 2025-01-01“…This also encourages studies on functional genes involved in metal transport, antioxidant, transcription regulation and stress response, providing candidates for genetic modification. Moreover, researchers have focused on the practical application and optimal managements in phytoremediation. …”
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10465
Estimating the Ultimate Bearing Capacity for Strip Footing Near and within Slopes Using AI (GP, ANN, and EPR) Techniques
Published 2021-01-01“…In this work, multiple data were collected on the soil and footing interface parameters, which included width of footing, depth of foundation, distance of slope from the footing edge, soil bulk density, slope and frictional angles, and bearing capacity factors of cohesion and overburden pressure determined for the case of a foundation on or adjacent to a slope. The genetic programming (GP), evolutionary polynomial regression (EPR), and artificial neural network (ANN) intelligent techniques were employed to predict the ultimate bearing capacity of footing on or adjacent to a slope. …”
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10466
Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology
Published 2025-01-01“…Abstract The emergence of the Omicron lineage represented a major genetic drift in SARS-CoV-2 evolution. This was associated with phenotypic changes including evasion of pre-existing immunity and decreased disease severity. …”
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10467
Combining metabolomic and transcriptomic approaches to assess and improve crop quality traits
Published 2021-01-01“…In addition, they allow to establish correlation between genotype and metabolite composition, and to clarify the genetic architecture of complex biochemical pathways, such as the accumulation of secondary metabolites in plants, many of them being highly valuable for the human diet. …”
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10468
Bioengineering in Solid-State Fermentation for next sustainable food bioprocessing
Published 2025-01-01“…A review of bioengineering strategies that optimize microbial growth and metabolite production in SSF systems is presented in this chapter, including novel bioreactor designs and genetic engineering of microorganisms combined with metabolic engineering. …”
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10469
Multi-objective Optimization Design of Planetary Cycloidal Reducer Structure with Considering Failure Correlation
Published 2022-05-01“…Taking a heavy-duty planetary cycloidal reducer as the research object,the reliability mathematical model of each subcomponent is constructed based on the force analysis of two-stage transmission system subcomponents,and the reliability is correlated and coupled by Copula function to construct a system reliability model considering failure correlation; on this basis,a multi-objective optimization model with minimum volume and maximum reliability is constructed,and NSGA-Ⅱ(Non-dominated sorted genetic algorithm-Ⅱ) algorithm is used to solve the model,and it is compared and analyzed with the system reliability model considering the independence assumption. …”
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10470
Practical Hybrid Machine Learning Approach for Estimation of Ultimate Load of Elliptical Concrete-Filled Steel Tubular Columns under Axial Loading
Published 2020-01-01“…The proposed model was Adaptive Neurofuzzy Inference System (ANFIS) combined with Real Coded Genetic Algorithm (RCGA), denoted as RCGA-ANFIS. The evaluation of the model was performed using the coefficient of determination (R2) and root mean square error (RMSE). …”
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10471
A Bilevel Programming Model to Optimize Train Operation Based on Satisfaction for an Intercity Rail Line
Published 2014-01-01“…The trains operation in different periods can be optimized through upper layer planning of the model, while considering the passenger flow distribution problem based on the Wardrop user equilibrium principle in the lower layer planning. Then, a genetic algorithm is designed according to model features for solving the upper laying. …”
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10472
Synaptic Wnt/GSK3β Signaling Hub in Autism
Published 2016-01-01“…The Wnt/β-catenin signaling pathway plays a central role in the development and regulation of the central nervous system and several genes belonging to the cascade have been genetically associated with ASDs. In the present paper, we review basic information regarding the role of Wnt/β-catenin signaling in excitatory/inhibitory balance (E/I balance) through the regulation of pre- and postsynaptic compartments. …”
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10473
Directed Evolution of Proteins through In Vitro Protein Synthesis in Liposomes
Published 2012-01-01“…IVC establishes the link between genetic information (genotype) and the protein translated from the information (phenotype), which is essential for all directed evolution methods, by encapsulating both in a nonliving microcompartment. …”
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10474
Fast and accurate deep learning scans for signatures of natural selection in genomes using FASTER-NN
Published 2025-01-01“…Abstract Deep learning classification models based on Convolutional Neural Networks (CNNs) are increasingly used in population genetic inference for detecting signatures of natural selection. …”
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10475
Adaptive Mechanisms of Mycobacterium tuberculosis: Role of fbiC Mutations in Dormancy and Survival
Published 2024-12-01“…While the fbiC gene contributes to dormancy, Mtb can achieve this state through multiple genetic and metabolic pathways, suggesting that it may still undergo dormancy even with functional impairments in fbiC. …”
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10476
Chromosome-scale assembly and annotation of the wild wheat relative Aegilops comosa
Published 2024-12-01“…Abstract Wild relatives of wheat are valuable sources for enhancing the genetic diversity of common wheat. Aegilops comosa, an annual diploid species with an MM genome constitution, possesses numerous agronomically valuable traits that can be exploited for wheat improvement. …”
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10477
Optimal control of chikungunya disease: Larvae reduction, treatment and prevention
Published 2012-02-01“…The nature of these arboviruses is complex since it conjugates human, environmental, biological and geographical factors.Recent researchs have suggested, in particular during the Réunion Island epidemic in 2006, that the transmission by Aedes albopictus (an Aedes genus specie) has been facilitated by genetic mutations of the virus and the vector capacity to adapt to non tropical regions.In this paper we formulate an optimal control problem, based on biological observations. …”
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10478
Relationships of Adrenoceptor Polymorphisms with Obesity
Published 2011-01-01“…Human obesity, hypertension, and diabetes have strong genetic as well as environmental determinants. Reduced energy expenditure and resting metabolic rate are predictive of weight gain, and the sympathetic nervous system participates in regulating energy balance through thermogenesis. …”
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10479
Annotation-free deep learning for predicting gene mutations from whole slide images of acute myeloid leukemia
Published 2025-02-01“…Using a dataset of 572 WSIs, the largest database with both WSI and genetic mutation information, our model achieved an AUC of 0.90 ± 0.08 for NPM1 and 0.80 ± 0.10 for FLT3-ITD in the testing cohort. …”
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10480
Czy inżynieria genetyczna? Za i przeciw modyfikowaniu naszej żywności
Published 2003-12-01“…The discussion about genetic engineering became present in mass media in UE and the USA. …”
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