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10441
Testing Homogeneity in a Semiparametric Two-Sample Problem
Published 2012-01-01“…This problem arises naturally from many statistical applications such as test for partial differential gene expression in microarray study or genetic studies for gene mutation. Under the semiparametric assumption g(x)=f(x)eα+βx, a penalized empirical likelihood ratio test could be constructed, but its implementation is hindered by the fact that there is neither feasible algorithm for computing the test statistic nor available research results on its theoretical properties. …”
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10442
Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning
Published 2024-11-01“…The synthetically enhanced data increases statistical power, uncovering less studied mechanisms associated with drug resistance, and refines the identification of genetic associations and clustering of cancer cell lines. …”
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10443
Cystic Fibrosis Atypical Forms Presentation: Edema, Anemia and Skin Lesions
Published 2021-04-01“…Cystic fibrosis or mucoviscidosis is the most common genetic disease in the Caucasian race characterized by thickening of secretions due to abnormal ion transport of epithelial cells, manifested with pancreatic insufficiency, progressive lung disease, alteration in the secretion of electrolytes in sweat, azoospermia in males and decreased fertility in females. …”
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10444
Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma
Published 2025-01-01“…Furthermore, our clinicoradiomic model predicts progression-free survival and correlates with treatment response. We also identify genetic variants and transcriptomic pathways associated with progression risk, highlighting links to tumor growth and immune response. …”
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10445
Integrated Thermal Insulation Packing and Vehicle Routing for Perishable Products in Community Group Purchase
Published 2021-01-01“…We designed a heuristic algorithm based on genetic algorithm to solve larger-scale problems. …”
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10446
Nuclear Reprogramming in Mouse Primordial Germ Cells: Epigenetic Contribution
Published 2011-01-01“…The unique capability of germ cells to give rise to a new organism, allowing the transmission of primary genetic information from generation to generation, depends on their epigenetic reprogramming ability and underlying genomic totipotency. …”
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10447
Aggregation‐based dual‐target probe for dual‐colour super‐resolution monitoring mitophagy and evaluating drugs regulating mitochondria
Published 2025-01-01“…Mitochondria dysfunction triggered by different drugs and genetic defect lead to elevated oxidative stress and higher levels of mitophagy. …”
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10448
Emergency Resource Location and Allocation in Traffic Contingency Plan for Sports Mega-Event
Published 2021-01-01“…Considering the slowness of convergence rate when the road network is large, a modified matrix real-coded genetic algorithm is designed with the crossover operator based on a greedy algorithm. …”
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10449
The Effect of Effective Factors on Consumer Behavior in Iran\'s Best Shopping Centers Based on the Principles of Urban Management
Published 2020-12-01“…The method of selecting shopping centers based on artificial intelligence studies has been done through genetic algorithm. The criteria for choosing the centers are optimal according to the principles of urban management. …”
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10450
Impact of maternal and offspring smoking and breastfeeding on oesophageal cancer in adult offspring
Published 2025-01-01“…We subsequently construct a polygenic risk score for oesophageal cancer to explore the influence of genetic factors. Our findings emphasize the importance of breastfeeding, and smoking cessation to prevent oesophageal cancer.…”
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10451
Comprehensive Analysis of the Main Agronomic Traits of Different Varieties (Lines) of Jute
Published 2025-12-01“…To investigate the genetic diversity of jute germplasm resources across different varieties (lines) and enhance the efficiency of comprehensive utilization of jute germplasm resources, this study employed a randomized block design to examine and analyze various agronomic traits of 15 jute varieties (lines) collected and to determine the fiber strength.The results demonstrated that the coefficients of variation for 22 agronomic traits across 15 varieties varied between 6.48% and 56.82%. …”
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10452
Elevated levels of neutrophils with a pro-inflammatory profile in Turner syndrome across karyotypes
Published 2025-02-01“…The increase in neutrophils was linked to TS clinical traits and to increased expression of the X-Y homologous gene TBL1X, suggesting a genetic basis, which may lead to neutrophil-driven inflammatory stress in TS. …”
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10453
Novel research model for in vitro immunotherapy: co-culturing tumor organoids with peripheral blood mononuclear cells
Published 2024-12-01“…Abstract Tumor organoids have emerged as powerful tools for in vitro cancer research due to their ability to retain the structural and genetic characteristics of tumors. Nevertheless, the absence of a complete tumor microenvironment (TME) limits the broader application of organoid models in immunological studies. …”
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10454
The first complete mitochondrial genome of Sumatran striped rabbit Nesolagus netscheri (Schlegel, 1880), and its phylogenetic relationship with other Leporidae
Published 2025-01-01“…Abstract Nesolagus netscheri, a Sumatran striped rabbit, is one of the rarest rabbits in the Leporidae family, and its genetic information is still limited. This study provides the first mitochondrial genome and molecular systematic characterization of the Sumatran striped rabbit, Nesolagus netscheri, Indonesia’s rarest rabbit. …”
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10455
Antibiotic, Pesticide, and Microbial Contaminants of Honey: Human Health Hazards
Published 2012-01-01“…Pesticide residues cause genetic mutations and cellular degradation and presence of antibiotics might increase resistant human or animal's pathogens. …”
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10456
Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets
Published 2025-01-01“…Especially, immunopeptidomics has provided key evidence to explain the genetic risk posed by HLA alleles. In this review, we shed light on how immunopeptidomics can be leveraged to discover potential autoantigens. …”
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10457
Characterization of Zebrafish von Willebrand Factor Reveals Conservation of Domain Structure, Multimerization, and Intracellular Storage
Published 2012-01-01“…The zebrafish is a powerful genetic model in which the hemostatic system is well conserved with mammals. …”
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10458
Sparse Antenna Array Design for MIMO Radar Using Multiobjective Differential Evolution
Published 2016-01-01“…Numerical examples are provided to demonstrate the advantages of the proposed approach over state-of-the-art methods, including DE and genetic algorithm.…”
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10459
On the edge of the eurasian steppes: the sarmatian culture in the 1st–3rd centuries ad east of the Carpathians
Published 2024-12-01“…The term ‘Sarmatians’ encompasses several nomadic groups with common genetic, linguistic or territorial ties, including the Iazyges, Roxolani, Alans, Siraces and Aorsi. …”
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10460
Primary exocrine pancreatic insufficiency in children (a clinical case of Shwachman-Diamond syndrome)
Published 2024-11-01“…The diagnosis is made in the presence of a characteristic combination of exocrine pancreatic function disorders, hematologic manifestations (neutropenia, thrombocytopenia, anemia), skeletal abnormalities and is confirmed by molecular genetic testing (mutation in the SBDS gene, which is localized on 7q or 11 and inversion of the 9th chromosome pair). …”
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