Enhancing Hydraulic Efficiency of Pelton Turbines Through Computational Fluid Dynamics and Metaheuristic Optimization by Guillermo Barragan, Sebastian Atarihuana, Edgar Cando, Victor Hidalgo

“…In this work, the NSGA-II multi objective genetic algorithm, numerical methods, and parametric design techniques found in the Autodesk Inventor professional 2023 CAD software were combined to perform the geometrical optimization of the Pelton bucket geometry. …”
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Machine learning and AI for advancing Parkinson's disease diagnosis: exploring promising applications by Shohreh Abdollahi, Ramin Safa

“…Accordingly, further research should explore deep learning methods and integrate additional data sources, such as gait analysis and genetic markers, to enhance diagnostic capabilities for Parkinson's disease.…”
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A Piecewise Hysteresis Model for a Damper of HIS System by Kaidong Tian, Bangji Zhang, Nong Zhang, Xuhui Liu, Jinchen Ji

“…The parameters of the model are identified based on genetic algorithm by setting the constraints of parameters according to their physical significances and the corresponding testing results. …”
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Green Logistics Location-Routing Optimization Solution Based on Improved GA A1gorithm considering Low-Carbon and Environmental Protection by Anqing Zhu, Youyun Wen

“…This paper proposes a green logistics location-routing optimization problem based on improved genetic algorithm (GA) from the perspective of low-carbon and environmental protection. …”
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A new class of natural anthelmintics targeting lipid metabolism by Hala Zahreddine Fahs, Fathima S. Refai, Suma Gopinadhan, Yasmine Moussa, Hin Hark Gan, Yamanappa Hunashal, Gennaro Battaglia, Patricia G. Cipriani, Claire Ciancia, Nabil Rahiman, Stephan Kremb, Xin Xie, Yanthe E. Pearson, Glenn L. Butterfoss, Rick M. Maizels, Gennaro Esposito, Antony P. Page, Kristin C. Gunsalus, Fabio Piano

“…In embryos, AFAs penetrate the eggshell and induce rapid developmental arrest. Genetic and biochemical tests reveal that AFAs inhibit POD-2, encoding an acetyl CoA carboxylase, the rate-limiting enzyme in lipid biosynthesis. …”
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La filière d’assainissement, quel rôle dans la lutte contre l’antibiorésistance ? by Arnal, Charlotte, Belhadj-Kaabi, Faten, Ingrand, Valérie

“…On the other hand, some authors warn against their potential involvement in the selection of new resistant germs, given the conditions conducive to the exchange of genetic material between microbial strains of various types and exposed to selective agents. …”
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Matching and Optimization of Two-speed Electric Vehicle Transmission System based on Cruise and Isight by Jigao Niu, Zhaojun Wang, Pengbo Zhang, Yunlong Yang, Kai Zhang, Chunhua Xu

“…On the premise that the dynamic performance meets the design requirements， in order to further improve the economy， a joint simulation model of Cruise and Isight is built， and an improved non-dominated sorting genetic algorithm （NSGA-Ⅱ） is adopted to optimize the transmission ratio of the transmission system with multiple objectives to achieve the best solution for power and economy. …”
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Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons by Reut Hilu-Dadia, Aseel Ghanem, Shelly Vogelesang, Malak Ayoub, Ketty Hakim-Mishnaevski, Estee Kurant

“…Our data demonstrate that santa-maria genetically interacts with simu and draper, while the protein product binds apoptotic cells and physically interacts with the SIMU protein. …”
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Path Optimization in Robotic Welding of Plate Heat Exchangers: An Improved Ant Colony Approach by Xianlong Chu, Xinning Li, Hu Wu, Xianhai Yang, Liyong Yang

“…Secondly, it combines the new perturbation strategy and the cross-mutation operation, proposes an improved genetic algorithm, and fuses it into the ACA, which increases the diversity of the ACA’s path searching and improves the ability of the local and global search. …”
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The Batten disease gene Cln3 is required for the activation of intestinal stem cell during regeneration via JAK/STAT signaling in Drosophila by Zihua Yu, Zihua Yu, Jinhua Yan, Zhiming Liu, Haiyan Wang, Guanzheng Luo, Haiyang Chen

“…Cell type-specific Gal4 screening reveals that the failure of ISC activation during regeneration caused by Cln3 loss is ISC-autonomous. Through genetic analyses, we elucidate that JAK/STAT signaling in ISCs is not activated with Cln3 depletion upon tissue damage, and functions downstream of Cln3. …”
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Application of On-Board Evolutionary Algorithms to Underwater Robots to Optimally Replan Missions with Energy Constraints by M. L. Seto

“…An on-board knowledge-based agent, based on a genetic algorithm, was designed and validated to replan a near-optimal AUV survey mission. …”
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Innovative approaches to boost mesenchymal stem cells efficacy in myocardial infarction therapy by Chuanfeng An, Yuan Zhao, Lipeng Guo, Zhijian Zhang, Chunxiao Yan, Shiying Zhang, Yujie Zhang, Fei Shao, Yuanyuan Qi, Xun wang, Huanan Wang, Lijun Zhang

“…Key approaches include optimizing cell delivery methods, enhancing cell engraftment, promoting cell functions through genetic and molecular modifications, enhancing the paracrine effects of stem cells, and leveraging biomaterials and tissue engineering techniques. …”
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What are biopharmaceuticals? by Abhay H. Pande, Yenisetti Rajendra Prasad, J. Anakha

“…With advancements in genetic engineering, biotechnology, and bioinformatics, the development and approval rates of new biopharmaceuticals have surged, placing them at the forefront of the pharmaceutical field. …”
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Non-canonical hepatic androgen receptor mediates glucagon sensitivity in female mice through the PGC1α/ERRα/mitochondria axis by Jie Chen, Yuanyuan Wu, Wanyu Hao, Jia You, Lianfeng Wu

“…By employing chemical and genetic approaches, we demonstrate that inhibiting the androgen receptor (AR) impairs the ability of glucagon to stimulate gluconeogenesis and lipid catabolism in primary hepatocytes and female mice. …”
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Effect of Tooth Profile Modification on Dynamic Tooth Load of Planetary Gear Train by Jiaming Zhou, Fengyan Yi, Xiangyang Xu, Junbin Lai, Yanfang Liu, Peng Dong

“…Finally, with the aim to obtain the optimal TPM for the minimization of dynamic load of PGT in both external and internal gear meshes, the genetic algorithm (GA) is employed. This research may shed light upon design optimization of PGT with respect to improvement of vibration performance by means of optimized TPM.…”
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Genome-wide profiling of tRNA modifications by Induro-tRNAseq reveals coordinated changes by Yuko Nakano, Howard Gamper, Henri McGuigan, Sunita Maharjan, Jiatong Li, Zhiyi Sun, Erbay Yigit, Sebastian Grünberg, Keerthana Krishnan, Nan-Sheng Li, Joseph A. Piccirilli, Ralph Kleiner, Nicole Nichols, Brian D. Gregory, Ya-Ming Hou

“…We assess tRNA modifications across five human cell lines and three mouse tissues and show that, while the landscape of modifications is highly variable throughout the tRNA sequence framework, it is stabilized for modifications that are required for reading of the genetic code. The coordinated changes have fundamental importance for development of tRNA modifications in protein homeostasis.…”
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Optimal Design and Dynamic Performance Analysis Based on the Asymmetric-Damping Vehicle ISD Suspension by Yujie Shen, Mengqi Jia, Kai Yang, Zhong Chen, Long Chen

“…The parameters of the proposed vehicle ISD suspension with symmetric-damping and asymmetric-damping features are optimized by means of the genetic algorithm in single-objective scenario and multiobjective scenario, respectively. …”
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Microwave-assisted enzymatic production of cosmetic ester 2-ethylhexyl oleate and myristate by Eko K. Sitepu, Emilia Abdulmalek, Helmina Sembiring, Rodiah N. Sari, Ella Parawita, Dea Hafizah, Novia Ramadhani, Maya R.S. Siregar, Firman Sebayang, Juliati Br. Tarigan

“…However, the availability of low-cost enzyme lipase derived from genetically modified microorganisms increases its competitiveness. …”
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Inflammatory Serum Biomarkers in Colorectal Cancer in Kazakhstan Population by L. Akhmaltdinova, V. Sirota, V. Zhumaliyeva, D. Babenko, I. Kadyrova, Z. Tauesheva, D. Taizhanova, A. Ibraeva, M. Maratkyzy, A. Turmukhambetova

“…Colorectal cancer is a type of oncopathology widespread in Kazakhstan. The genetic component, as well as the possible etiopathogenetic mechanisms, is widely studied. …”
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A PMBGA to Optimize the Selection of Rules for Job Shop Scheduling Based on the Giffler-Thompson Algorithm by Rui Zhang, Cheng Wu

“…Under such circumstances, a probabilistic model-building genetic algorithm (PMBGA) is proposed to optimize the sequence of selected rules. …”
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