Activity-Dependent NPAS4 Expression and the Regulation of Gene Programs Underlying Plasticity in the Central Nervous System by José Fernando Maya-Vetencourt

“…This view has been recently challenged by experimental strategies based on the enhancement of environmental stimulation levels, genetic manipulations, and pharmacological treatments, which all have demonstrated that the adult brain retains a degree of plasticity that allows for a rewiring of neuronal circuitries over the entire life course. …”
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HisCoM-GGI: Software for Hierarchical Structural Component Analysis of Gene-Gene Interactions by Sungkyoung Choi, Sungyoung Lee, Taesung Park

“…We expect that HisCoM-GGI software will provide advanced accessibility to researchers in genetic interaction studies and a more effective way to understand biological mechanisms of complex diseases.…”
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New horizons in the treatment of psoriasis: Modulation of gut microbiome by Mojtaba Memariani, Hamed Memariani

“…Psoriasis is a complex disease with multiple factors contributing to its development, such as diet, lifestyle, genetic predisposition, and the microbiome. This paper has a dual purpose. …”
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Current Trends in the Molecular Classification of Renal Neoplasms by Andrew N. Young, Viraj A. Master, Mahul B. Amin

“…The primary approach to diagnosis is by light microscopy, using the World Health Organization (WHO) classification system, which defines histopathologic tumor subtypes with distinct clinical behavior and underlying genetic mutations. However, light microscopic diagnosis of RCC subtypes is often difficult due to variable histology. …”
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Design principles for engineering bacteria to maximise chemical production from batch cultures by Ahmad A. Mannan, Alexander P. S. Darlington, Reiko J. Tanaka, Declan G. Bates

“…We show that engineering genetic circuits to switch cells to a high synthesis-low growth state after first growing to a large population can further improve performance. …”
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A new pheretimoid earthworm of the genus Metaphire Sims & Easton, 1972 (Oligochaeta, Megascolecidae) from northeastern China with data from the mitochondrial genome by Huifeng Zhao, Anne Charis N. Han, Min Liu, Yufeng Zhang, Nonillon M. Aspe, Pu Miao, Donghui Wu

“…The molecular phylogenetic position of M. liaoningensis sp. nov. within the M. houlleti species group is performed by COI and mitogenomic data, respectively. The COI K2P genetic distance between the new species and the other species within the M. houlleti species group was at least 16%. …”
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NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration by Jiangyuan Gao, Ruozhou Tom Liu, Sijia Cao, Jing Z. Cui, Aikun Wang, Eleanor To, Joanne A. Matsubara

“…AMD is a multifactorial disease influenced by both genetic and environmental risk factors. Progression of AMD is characterized by an increase in the number and size of drusen, extracellular deposits, which accumulate between the retinal pigment epithelium (RPE) and Bruch’s membrane (BM) in outer retina. …”
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SOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease by James J. Mason, Bart O. Williams

“…The study of rare human genetic disorders has often led to some of the most significant advances in biomedical research. …”
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Multi-objective Optimization of Dimensional Parameter for 4-PRP_aR Parallel Mechanism by Jian Yi, Bing He, Linxian Che, Jie Li

“…A multi-objective optimization model is constructed to formulate the design problem of dimensional parameters on the maximizing radius of RETW and average transmission indices， and the fast and elitist multi-objective genetic algorithm combined with differential evolution algorithm is used to solve this problem. …”
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Oxidative stress induced protein aggregation via GGCT produced pyroglutamic acid in drug resistant glioblastoma by Deanna Tiek, Xiao Song, Xiaozhou Yu, Runxin Wu, Rebeca Iglesia, Alicia Catezone, Katy McCortney, Jordain Walshon, Craig Horbinski, Pouya Jamshidi, Rudolph Castellani, Robert Vassar, Jason Miska, Bo Hu, Shi-Yuan Cheng

“…We further observe that the byproduct of GGCT—pyroglutamic acid—can bind aggregating proteins and that genetic and pharmacological inhibition of GGCT prevents protein aggregation. …”
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From Entity Description to Semantic Analysis: The Case of Theodor Fontane’s Notebooks by Martin de la Iglesia, Mathias Göbel

“…Within the last few decades, TEI has become a major instrument for philologists in the digital age, particularly since a set of mechanisms has recently been incorporated which facilitates the encoding of genetic editions. Editors use the XML syntax while aiming to preserve the quantity and quality of old books and manuscripts and publish many more of them online, mostly under free licenses. …”
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Population age structure and conservation status of Ferula sinkiangensis (Apiaceae) in Xinjiang, China by Tianxing Liu, Qiumei Cao, Lei Yang, Zhaoping Yang, Wenjun Li

“…However, the number of mature individuals was small, raising concerns about the risk of genetic drift and inbreeding. This species is also threatened by habitat destruction and inappropriate collection practices. …”
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Emergence of Non-Serotype b Encapsulated Haemophilus influenzae as a Cause of Pediatric Meningitis in Northwestern Ontario by Pouya Sadeghi-Aval, Raymond SW Tsang, Frances B Jamieson, Marina Ulanova

“…The present article describes these cases along with the characteristics of recent H influenzae isolates from the region, (ie, their genetic background and antibiotic sensitivity). The findings point to the clonal nature of circulating Hia strains as well as to an increase in frequency and severity of pediatric invasive H influenzae infections in northwestern Ontario.…”
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Application and Comparative Study of Large Language Model in Early Prediction of Glaucoma by Xu Manyi

“…The study selected a variety of large language models, including Chat Generative Pre-trained transformer (ChatGPT), to build a glaucoma prediction model and analyze clinical data, genetic information, and lifestyle data of patients. …”
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Current Situation of Goose Astrovirus in China: A Review by Dan Ren, Hongliang Zhang, Xiaoou Ye, Xiuzhi Jia, Ruiming Chen, Tingbing Tang, Jianqiang Ye, Songquan Wu

“…The purpose of this review is to summarize the latest research progress on GAstV in recent years, mainly focusing on the genetic evolution, pathogenesis, diagnostic detection, and control strategies of GAstV, aiming to provide a reference for scientific prevention and control of GAstV infection.…”
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Mucin-producing urothelial-type adenocarcinoma of the prostate with a gene mutation characteristic of intestinal adenocarcinoma: case report and literature review by Ao Yu, Ao Yu, Hongbo Su, Peiling Yu, Siqi Cai, Shuaixian Mu, Jinhui Yu, Qianting Lu, Yuan Miao, Ailin Li

“…Next-generation sequencing (NGS) identified genetic alterations similar to those found in intestinal adenocarcinoma. …”
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Optimization in Construction Management Using Adaptive Opposition Slime Mould Algorithm by Pham Vu Hong Son, Luu Ngoc Quynh Khoi

“…In order to compare AOSMA with a nondominated sorting genetic algorithm III (NSGA III), multiobjective particle swarm optimization (MOPSO), LHS-based NSGA III, and a hybrid model of MAWA (MAWA-TLBO, MAWA-GA, MAWA-AS, and MAWA-ACS-SGPU) and to assess the model’s potential and viability, performance evaluation indexes are applied. …”
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Improved Ant Algorithms for Software Testing Cases Generation by Shunkun Yang, Tianlong Man, Jiaqi Xu

“…The proposed technique will be compared with random algorithm (RND) and genetic algorithm (GA) in terms of both efficiency and coverage. …”
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Live Visualization of Calcified Bones in Zebrafish and Medaka Larvae and Juveniles Using Calcein and Alizarin Red S by Rina Koita, Sae Oikawa, Taisei Tani, Masaru Matsuda, Akinori Kawamura

“…Zebrafish and medaka are valuable model vertebrates for genetic studies. The advent of CRISPR-Cas9 technology has greatly enhanced our capability to produce specific gene mutants in zebrafish and medaka. …”
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Immune Disorders in Hashimoto’s Thyroiditis: What Do We Know So Far? by Aleksandra Pyzik, Ewelina Grywalska, Beata Matyjaszek-Matuszek, Jacek Roliński

“…This review of literature attempts to identify the factors that are involved in the pathogenesis of Hashimoto thyroiditis, an immune defect in an individual with genetic susceptibility accompanied with environmental factors. …”
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