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10201
Virus-inspired biogenic delivery system for advancing cancer therapy
Published 2025-03-01“…VLPs lack viral virulence, resulting from a viral genetic material deficiency. In vaccine research, Virus-mimic nanovesicles have been effectively verified against cancer via the immunogenicity and the pharmacological effect of drug molecules delivered to mediate an immune response in the body. …”
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10202
Polymorphisms of Homologous Recombination RAD51, RAD51B, XRCC2, and XRCC3 Genes and the Risk of Prostate Cancer
Published 2015-01-01“…Genetic polymorphisms in DNA repair genes may induce individual variations in DNA repair capacity, which may in turn contribute to the risk of cancer developing. …”
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10203
Novel Trends in Electrochemical Biosensors for Early Diagnosis of Alzheimer’s Disease
Published 2021-01-01“…Standard laboratory methodology could be improved by analyzing a combination of currently estimated markers along with neurotransmitters and genetic markers from blood samples, which make the test for AD diagnosis available to the wide public.…”
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10204
Specialized Bacteroidetes dominate the Arctic Ocean during marine spring blooms
Published 2024-11-01“…Altogether, these genomic features point to the genetic adaptations that promote the dominance of Bacteroidetes during phytoplankton blooms.…”
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10205
Characterization of the complete plastid genome of Clivia mirabilis (Amaryllidaceae)
Published 2025-01-01“…Our findings could be used to identify and analyze the genetic diversity of C. mirabilis and provide new data for taxonomic and phylogenetic studies of Clivia.…”
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10206
Papillion-Lefèvre Syndrome: Periodontists’ Perspective
Published 2015-01-01“…Papillion-Lefèvre Syndrome is a very rare disorder of autosomal recessive inheritance distinguished by palmar plantar hyperkeratosis and early onset of periodontitis affecting the dentition. Genetic studies have identified a mutation in the major gene locus of chromosome 11q14 with loss of function. …”
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10207
Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity
Published 2025-01-01“…Extrapolation of cell-type results to brain regions reveals the whole-brain impact of schizophrenia genetic risk, with subregions in the hippocampus and amygdala exhibiting the most significant enrichment of SNP-heritability. …”
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10208
Analysis of Direct and Indirect Selection and Indices in Bread Wheat (Triticum aestivum L.) Segregating Progeny
Published 2018-01-01“…Three selection methods including direct and indirect selection along with selection index based on the phenotypic values of eleven traits of agronomic interest were assessed for their application in F4 bread wheat progenies. Significant genetic variation existed among parents and crosses for the traits measured. …”
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10209
An overview of the Bantoid languages
Published 2024-12-01“… The Bantoid languages are a body of some 150-200 languages positioned geographically between Nigeria and Cameroun. They do not form a genetic group, but all are in some way related to Bantu more closely than other branches of Benue-Congo. …”
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10210
Research on Optimization of Aircraft Climb Trajectory considering Environmental Impact
Published 2021-01-01“…Finally, the multiobjective model is solved by genetic algorithm. The B737-800 civil aviation aircraft is selected for simulation experiment to analyze the impact of speed change on the optimization target. …”
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10211
Initial Immunopathogenesis of Multiple Sclerosis: Innate Immune Response
Published 2013-01-01“…The immunological phenomena that lead to the activation of autoreactive T cells to myelin sheath components are the result of multiple and complex interactions between environment and genetic background conferring individual susceptibility. …”
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10212
A Support Vector Machine Model with Hyperparameters Optimised by Mind Evolutionary Algorithm for Assessing Permeability of Rock
Published 2020-01-01“…Based on the constructed database, a Support Vector Machine (SVM) model with hyperparameters optimised by Mind Evolutionary Algorithm (MEA) was proposed to predict the permeability of rock. Meanwhile, the Genetic Algorithm- (GA-) and Particle Swarm Algorithm- (PSO-) SVM models were constructed to compare the improving effects of MEA on the foretelling accuracy of machine learning models with those of GA and PSO, respectively. …”
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10213
From flower to fruit: fruit growth and development in olive (Olea europaea L.)—a review
Published 2023-11-01“…It is concluded that the different mechanisms regulating the different phases of fruit development, from pistil abortion to fruit set and fruit size, can be considered as different aspects of the same overall strategy, that is, adjusting fruit load to the available resources while striving to achieve the genetically determined fruit size target and the male and female fitness targets.…”
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10214
Program for Studying Intergenerational Transmissions in Infant Mortality Using the Intermediate Data Structure (IDS)
Published 2018-05-01“…Studies conducted in historical populations and developing countries have evidenced the existence of clustering in infant deaths, which could be related to genetic inheritance and/or to social and cultural factors such as education, socioeconomic status or parental care. …”
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10215
Optimal Design and Analysis of Traction Steering Mechanism for Loading Transport Vehicle
Published 2021-05-01“…A trapezoidal traction steering mechanism based on Ackerman principle is designed, and uses the sequential quadratic programming genetic algorithm in multivariate nonlinear programming to optimize the specific dimensions of the trapezoidal traction steering mechanism, the size parameters which more satisfy the Ackerman principle are obtained. …”
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10216
Multiple Sclerosis Presenting with Facial Twitching (Myokymia and Hemifacial Spasms)
Published 2017-01-01“…The etiology is insufficiently understood. Autoimmune, genetic, viral, and environmental factors have been hypothesized. …”
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10217
Design and Optimization of the Master Manipulator of Minimally Invasive Surgery Robots
Published 2024-05-01“…The Jacobian matrix of the master manipulator is solved, the comprehensive performance index of the master manipulator is defined based on the global performance dexterity index and the workspace utilization ratio, and the key link scale parameters are optimized by the genetic algorithm. The results show that the comprehensive performance index of the master manipulator after optimization is 18.41% higher than that before optimization, and the master manipulator is more compact, has better performance besides meeting the design requirements of the workspace.…”
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10218
Ecology of prophage-like elements in Bacillus subtilis at global and local geographical scales
Published 2025-01-01“…Genome sequences from the NCBI database and riverbank soil isolates reveal prophages primarily related to mobile genetic elements in laboratory strains. Distinct and previously unknown prophages in local isolates prompt an investigation into factors shaping prophage presence, with phylogenetic relatedness predicting the prophage repertoire slightly better than geographical origin. …”
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10219
Immunopathogenesis of spondyloarthropathies – Concept of major histocompatibility locus-I-opathy
Published 2021-01-01“…Spondyloarthropathies (SpA) are a group of overlapping disorders sharing certain common clinical features and genetic associations. Historically, most of the research into the pathogenesis of SpA and other types of chronic arthritis have conventionally focused on the adaptive immune system. …”
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10220
The role of multiomics in revealing the mechanism of skin repair and regeneration
Published 2025-01-01“…While genomic studies identify the genetic basis of wound healing, transcriptomics and proteomics uncover the dynamic changes in gene and protein expression, and metabolomics provides a snapshot of metabolic alterations associated with wound healing. …”
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