Interactive Visualization for Patient-to-Patient Comparison by Quang Vinh Nguyen, Guy Nelmes, Mao Lin Huang, Simeon Simoff, Daniel Catchpoole

“…This paper presents a methodology that is implemented as an interactive visual analysis technology for extracting knowledge from complex genetic and clinical data and then visualizing it in a meaningful and interpretable way. …”
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Optimization Model of Traffic Sensor Layout considering Traffic Big Data by Xu Sun, Zixiu Bai, Kun Lin, Pengpeng Jiao, HuaPu Lu

“…The model is solved by the tolerant lexicographic method based on a genetic algorithm. A case study shows that the model reflects the influence of multisource data sharing and fault conditions and satisfies the origin-destination coverage constraint to achieve the multiobjective optimization of traffic sensor layout.…”
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Gearbox Fault Diagnosis Based on ALIF-PE-GOLSSVM by Huang Ying, Li Ximei, Ye Renhu, Wang Rui

“…Then the PE value with component (C-PE value) is calculated to obtain the multi-scale characteristics of vibration signals. Then the genetic algorithm is used to optimize the least squares support vector machine (LSSVM). …”
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THERAPEUTIC GENE EDITING FOR HEMOGLOBINOPATHIES by Ugo Testa, Giuseppe Leone, Maria Domenica Cappellini

“…Initial studies of gene therapy for hemoglobinopathies involved the use of lentiviral vectors to add functional copies of the gene encoding b-globin in defective CD34 cells; more recently, gene editing techniques have been used involving either CRISPR-Cas9, transcription activation-like effector protein nuclease, zinc finger nuclease, and base editing to either induce fetal hemoglobin production at therapeutic levels or to genetically repair the underlying molecular defect causing the disease. …”
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A case of massive hematoma: reflections on hypermobile Ehlers-Danlos syndrome by QingHua Liu, Ganhua Zeng, Yu Xiong, Chenyang Xu

“…Ehlers-Danlos Syndrome (EDS) refers to a group of connective tissue disorders characterized by significant clinical and genetic variability, affecting multiple systems in the body. …”
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Retinal Ischemia as a Presenting Ocular Sign of Neurofibromatosis Type 2 by Binbin Zhao, Yan Yan

“…Brain MRI showed bilateral acoustic neuroma, parasellar meningioma, and cervical extramedullary tumor. The genetic test confirmed the diagnosis of NF2. Conclusions and Importance. …”
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Arv1; a “Mover and Shaker” of Subcellular Lipids by J. Jose Corbalan, Karla K. Frietze, Joseph Nickels, Stephen L. Sturley

“…The composition of eukaryotic membranes reflects a varied but precise amalgam of lipids. The genetic underpinning of how such diversity is achieved or maintained is surprisingly obscure, despite its clear metabolic and pathophysiological impact. …”
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The Role of Beta HPV Types and HPV-Associated Inflammatory Processes in Cutaneous Squamous Cell Carcinoma by Mircea Tampa, Cristina Iulia Mitran, Madalina Irina Mitran, Ilinca Nicolae, Adrian Dumitru, Clara Matei, Loredana Manolescu, Gabriela Loredana Popa, Constantin Caruntu, Simona Roxana Georgescu

“…Dysregulation of the immune system (chronic inflammation and immunosuppression), environmental factors (ultraviolet radiation), and genetic factors are the most important cofactors involved in beta HPV-related carcinogenesis. …”
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The Migraine-Ischemic Stroke Relation in Young Adults by Alessandro Pezzini, Elisabetta Del Zotto, Alessia Giossi, Irene Volonghi, Paolo Costa, Giorgio Dalla Volta, Alessandro Padovani

“…In this regard, four major issues might be considered which may be summarized as follows: (1) the migraine-ischemic stroke relation is influenced by specific risk factors such as patent foramen ovale or endothelial dysfunction and more frequent in particular conditions like spontaneous cervical artery dissection; (2) migraine is associated with an increased prevalence of cardiovascular risk factors; (3) the link is caused by migraine-specific drugs; (4) migraine and ischemic vascular events are linked via a genetic component. In the present paper, we will review epidemiological studies, discuss potential mechanisms of migraine-induced stroke and comorbid ischemic stroke, and pose new research questions.…”
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Feminist Perspectives on Reproduction and Motherhood and/as Cultivation: Ruth Ozeki’s All Over Creation by Ina Batzke

“…This article discusses women’s reproductive agency and/or suppression in connection with biotechnological innovations in the agricultural industry, especially genetically modified crops (GMOs). To do so, it takes up Ruth Ozeki’s creative response on this interconnection, the 2002 novel All Over Creation, which utilizes a fictional farmer community in Idaho to address broader cultural issues such as sexism, racism, and reproductive justice. …”
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Natural selection and evolution: evolving concepts by Andre J. van Wijnen, Eric Lewallen

“…Current evolutionary models incorporate different adaptive and non-adaptive processes based on molecular genetic changes and how DNA is modified over time in unicellular species, or in germline versus somatic cells in metazoan species. …”
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Aneuploidy Mechanisms in Human Colorectal Preneoplastic Lesions and Barrett’s Esophagus. Is There a Role for K-Ras and p53 Mutations? by Walter Giaretti

“…The link of aneuploidy and heteroploidy in human solid tumours with early genetic events is poorly understood. The study of human preneoplastic precursor lesions, i.e., colorectal adenomas, chronic ulcerative colitis lesions, and Barrett’s esophagus, as considered in this review, appears particularly useful to achieve this aim. …”
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MENINGIOMAS IN DOGS: EPIDEMIOLOGY, ADVANCEMENTS IN DIAGNOSTIC IMAGING AND THERAPEUTIC OPTIONS by Sorin Marian Mârza, Radu Lăcătuș, Felix Daniel Lucaci, Robert Cristian Purdoiu

“…However, challenges persist in managing tumor recurrence and malignant forms, highlighting a need for further research into genetic markers and new therapeutic approaches. This review underscores the necessity for advanced diagnostic capabilities and tailored treatment strategies to improve prognosis and quality of life in affected dogs.…”
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Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders? by Kristina Harris, Amira Kassis, Geneviève Major, Chieh J. Chou

“…Gut microbiota has evolved with humans as a mutualistic partner, but dysbiosis in a form of altered gut metagenome and collected microbial activities, in combination with classic genetic and environmental factors, may promote the development of metabolic disorders. …”
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REVIEW ON DORMANCY, CAUSES, USES, AND MEASURES OF OVERCOMING IT by Prakash Awasthi

“…The majority of both human and animal diets are made up mostly of seed, which is also the foundation and the first input used in the transmission of genetic features in crop development. Seed dormancy, a physiological phenomenon in plants that can be brought on by internal or external stimuli, prevents seeds from sprouting even under ideal circumstances. …”
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Drug molecular representations for drug response predictions: a comprehensive investigation via machine learning methods by Meisheng Xiao, Qianhui Zheng, Paul Popa, Xinlei Mi, Jianhua Hu, Fei Zou, Baiming Zou

“…However, the comparative effectiveness of combining these representations with genetic profiles for DRP remains unclear. This study conducts a comprehensive evaluation of the efficacy of various drug molecular representations employing cutting-edge machine learning models under various experimental settings. …”
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A universal DNA microarray for rapid fish species authentication by Patrizia Bade, Sebastian Stix, Kristina Kappel, Jan Fritsche, Ilka Haase, Andrew Torda, Nils Wax, Markus Fischer, Dirk Brandis, Ute Schröder

“…A universal set of 100 DNA probes (based on the genetic marker genes 16S ribosomal RNA and cytochrome b) generated species-specific DNA probe patterns for all 86 analyzed fish specimens. …”
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Nutrigenomic Functions of PPARs in Obesogenic Environments by Soonkyu Chung, Young Jun Kim, Soo Jin Yang, Yunkyoung Lee, Myoungsook Lee

“…In this review, we aim to highlight the critical role of PPARs in the modulation of adiposity and subsequent metabolic adaptation in response to dietary challenges and genetic modifications. Understanding the changes in obesogenic environments as a consequence of PPARs/nutrient interactions may help expand the field of individualized nutrition to prevent obesity and obesity-associated metabolic comorbidities.…”
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Importance of Human Faecal Biobanking: From Collection to Storage by Lewandowska Izabela, Grzech Katarzyna, Krzysztoń-Russjan Jolanta

“…The freezing and storage conditions of faecal samples in biobanks influence the preservation of the integrity and stability of genetic material and play a crucial role in scientific and clinical research quality. …”
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Walking in the footsteps of the forefathers. The concept of “ancestry” between political use of molecular biology and indigenous territory, understood as a relationship between the... by Laura Volpi

“…Thus, despite having assimilated an ancestral-genetic discourse, they reshape it in light of a more relational conception of territory. …”
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