Selective Autophagy in Drosophila by Ioannis P. Nezis

“…Drosophila is an excellent genetically modifiable model organism exhibiting high conservation in the autophagic machinery. …”
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Mining the Ocean Genome: Global Bioprospecting Expeditions and Genomic Extractivism on the Oceanic Frontier by Amedeo Policante, Erica Borg

“…The article follows the ongoing transformation of genomic science into an industry – dedicated to the systematic extraction, abstraction and manipulation of genetic material – and considers the new types of oceanic exploration that genomic research both presupposes and fosters. …”
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Simultaneous Bilateral Spontaneous Pneumothorax Revealed Birt-Hogg-Dubè Syndrome by Alessandro Tamburrini, Francesco Sellitri, Federico Tacconi, Francesco Brancati, Tommaso Claudio Mineo

“…In this case, we firstly report the concurrence of these rare conditions, as a patient presenting a simultaneous bilateral spontaneous pneumothorax was diagnosed with Birt-Hogg-Dubè syndrome based on the typical radiological findings and genetic testing of the folliculin gene located on chromosome 17.…”
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The Relationship between Frequently Used Glucose-Lowering Agents and Gut Microbiota in Type 2 Diabetes Mellitus by You Lv, Xue Zhao, Weiying Guo, Ying Gao, Shuo Yang, Zhuo Li, Guixia Wang

“…The etiology of diabetes mellitus can be attributed to genetic and/or environmental factors. Current evidence suggests the association of gut microbiota with metabolic diseases. …”
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Neurotrophic Receptor Tyrosine Kinase 2 (NTRK2) Alterations in Low-Grade Gliomas: Report of a Novel Gene Fusion Partner in a Pilocytic Astrocytoma and Review of the Literature by Siobhan S. Pattwell, Eric Q. Konnick, Yajuan J. Liu, Rebecca A. Yoda, Laligam N. Sekhar, Patrick J. Cimino

“…Hereditary pilocytic astrocytoma is often associated with germline genetic alterations in the tumor suppressor NF1, the gene responsible for the syndrome neurofibromatosis type 1. …”
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Cholangiocyte organoids for disease, cancer, and regenerative medicine by Munemasa Nagao, Akihisa Fukuda, Hirotaka Kashima, Sho Matsuyama, Kei Iimori, Shinnosuke Nakayama, Kenta Mizukoshi, Munenori Kawai, Go Yamakawa, Mayuki Omatsu, Mio Namikawa, Tomonori Masuda, Yukiko Hiramatsu, Yu Muta, Takahisa Maruno, Yuki Nakanishi, Tatsuaki Tsuruyama, Hiroshi Seno

“…This review also discusses the use of organoids in genetically engineered mouse models to provide mechanistic insights into tumorigenesis and cancer progression. …”
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PROBLEMS OF STATE AND LEGAL ADMINISTRATION IN THE SPHERE OF FOREST SEED PRODUCTION by Yu. N. Gagarin

“…The process of formation and development of the unified genetic and selection complex (UGSC) of forestry in Russia and the reasons for its subsequent degradation are covered. …”
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Clinical presentation, diagnosis and treatment of intrahepatic cholestasis of pregnancy by Yu. B. Uspenskaya, A. A. Sheptulin

“…The etiology and pathogenesis of ICP are related to disorders of bile acid metabolism caused by hormonal factors (elevation of estrogen and progesterone levels) and genetic predisposition. The leading clinical signs of ICP include pruritus and jaundice that develop most commonly in the third trimester of pregnancy, and characteristic changes of laboratory scores: increase in bile acid level (over 10 mcmol/l) and moderate elevation of transaminase activity. …”
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Mucosal-adapted bacteriophages as a preventive strategy for a lethal Pseudomonas aeruginosa challenge in mice by Luiz Felipe Leomil Coelho, Mateus de Souza Terceti, Sergio Pereira Lima Neto, Raíne Piva Amaral, Ana Luisa Cauvila dos Santos, William Permagnani Gozzi, Bianca Andrade de Carvalho, Gustavo Aparecido da Cunha, Maria Fernanda Romboli Durante, Lais Sanchietta, Giovana Soares Marangoni, Matheus Luca Carotta Gabriel, Luiz Cosme Cotta Malaquias, Eliana Leonor Hurtado Celis, Giovanna de Souza Apolinário, João Pessoa Araujo Junior, Carine Ervolino de Oliveira, Victoria Fulgencio Queiroz, Gabriel Magno de Freitas Almeida

“…Both are similar in morphology and closely related genetically. However, phage VAC3 is more efficient in replicating in mucin-exposed P. aeruginosa in vitro and is preferentially held in the respiratory tract of C57BL/6 mice. …”
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Assembly and characterization of the complete mitogenome of Bauhinia purpurea (Leguminosae) by Siqi Xie, Yong Chen, Danjing Zheng, Shukai Luo, Shiyuan Meng, Yan Zhong

“…Here, we sequenced and assembled the mitogenome of B. purpurea to provide a useful genetic resource for further evolutionary studies. …”
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Robust Framework to Combine Diverse Classifiers Assigning Distributed Confidence to Individual Classifiers at Class Level by Shehzad Khalid, Sannia Arshad, Sohail Jabbar, Seungmin Rho

“…For this purpose, we applied genetic algorithm to search for an optimal weight vector on which classifier ensemble is expected to give the best accuracy. …”
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Ultrasound Radiogenomics-based Prediction Models for Gene Mutation Status in Breast Cancer by Zhai Yue, Tan Dianhuan, Lin Xiaona, Lv Heng, Chen Yan, Li Yongbin, Luo Haiyu, Dan Qing, Zhao Chenyang, Xiang Hongjin, Zheng Tingting, Sun Desheng

“…These features, including shape, texture, and intensity variations, are correlated with specific genetic mutations such as TP53 and PIK3CA, critical for cancer progression and treatment response. …”
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A membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina by Gaia Ziraldo, Sara Cupini, Valentina Sesti, Emanuela Delfino, Guglielmo Lanzani, Chiara Bertarelli, Fabio Benfenati, Stefano Di Marco

“…Here, we show that Ziapin2, a membrane photoswitch that modulates neuronal capacitance and excitability in a light-dependent manner, is capable of reinstating, in mouse and rat genetic models of photoreceptor degeneration, brisk and sluggish ON, OFF, and ON-OFF responses in retinal ganglion cells evoked by full-field stimuli, with reactivation of their excitatory and inhibitory conductances. …”
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Bilateral Total Hip and Right Knee Arthroplasty in a Sickle Cell Disease Patient with Multiple Joint Osteonecrosis: A Case Report and Literature Review by Michael Ebiyon Ugbeye, Kehinde Adesola Alatishe, Chukwuebuka Okezie

“…Sickle cell disease is an autosomal recessive genetic disorder with the underlying pathology, resulting in sickling of the red blood cells in deoxygenated conditions. …”
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Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure by Misako Katsuura, Jun Homma, Yuhei Higashi, Hidekazu Sekine, Tatsuya Shimizu

“…Furthermore, in vivo experiments showed that IPP-cultured cell sheets enhanced the secretion of Gaussian luciferase by genetically modified mesenchymal stem cells. These findings highlight the IPP method as a technique that simultaneously enables the thickening of planar tissues and the construction of vascular networks. …”
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Understanding glioblastoma at the single-cell level: Recent advances and future challenges. by Yahaya A Yabo, Dieter Henrik Heiland

“…Over the past decade, single-cell transcriptomics has enabled the molecular characterization of individual cells within glioblastomas, providing previously unattainable insights into the genetic and molecular features that drive tumorigenesis, disease progression, and therapy resistance. …”
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Osteogenesis Imperfecta (Type IV) with Dental Findings in Siblings by Shishir Ram Shetty, Deepa Dsouza, Subhas Babu, Preethi Balan

“…The most important oral finding in OI is the presence of yellowish-brown-coloured brittle teeth characteristic of dentinogenesis imperfecta. Genetic factors play a very important role in the pathogenesis of OI either as a dominant or recessive factor. …”
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Atopic dermatitis - the review by Joanna Wrona, Aleksandra Kaźmierczyk, Jędrzej Kęsik, Daria Madycka, Kacper Michta, Małgorzata Słaboń, Aleksandra Wójcik, Karol Stępniak, Wiktor Telega, Kinga Wnuczek

“… Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by a disrupted epidermal barrier, immune dysregulation, and genetic predisposition. Affecting individuals across all age groups, AD presents with recurrent flare-ups and varying clinical patterns depending on age. …”
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Management and Reconstruction of a Gastroesophageal Junction Adenocarcinoma Patient Three Years after Pancreaticoduodenectomy: A Surgical Puzzle by Dionysios Dellaportas, James A. Gossage, Andrew R. Davies

“…The reconstruction controversies and considerations are highlighted. Discussion. Genetic, environmental, and lifestyle factors are common for several gastrointestinal malignancies. …”
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Ureteropelvic Junction Obstruction and Parathyroid Adenoma: Coincidence or Link? by Salah Termos, Majd AlKabbani, Tim Ulinski, Sami Sanjad, Henri Kotobi, Francois Chalard, Bilal Aoun

“…Further studies showed primary hyperparathyroidism and genetic analysis revealed a CDC73 mutation (initially HRPT2). …”
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