Pulmonary artery aneurysm as a rare manifestation of Alpha-1 antitrypsin deficiency by Mark A. Colantonio, Sanjana Aggarwal, Himanshu Deshwal

“…Alpha-1 antitrypsin is a relatively well-known genetic disease known to primarily affect the lungs and liver. …”
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Activity of the Tyumen Commodity Exchange (1910–1917) by L. V. Merkulova

“…Based on the study of press materials and unpublished sources from the funds of the State Archive of the Tyumen region and the application of historical methods such as historical-comparative, historical-genetic, statistical, the aim of the study is achieved — the mechanism of the exchange is analyzed, the main directions of its activities are identified, its efficiency is assessed.…”
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CONTENTS: VOL. 177, issue 4 by Editorial Article

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CONTENTS by Editorial Article

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CONTENTS by Editorial Article

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SUMMARY by Editorial Article

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Antropología simétrica y procesos de curación con ayahuasca by Mauricio Genet Guzmán Chávez

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CONTENTS by Editorial Article

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Morphological characterization and yield of pepper (Piper nigrum L.) types grown in Morogoro District, Tanzania by Abdul Jafari Shango, Ramadhani Omari Majubwa, Amon Petro Maerere

“…This may limit information on germplasm collection or genetic resource for plant improvement and trade in markets with variety specifications. …”
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Exploring the role of splicing in TP53 variant pathogenicity through predictions and minigene assays by Cristina Fortuno, Inés Llinares-Burguet, Daffodil M. Canson, Miguel de la Hoya, Elena Bueno-Martínez, Lara Sanoguera-Miralles, Sonsoles Caldes, Paul A. James, Eladio A. Velasco-Sampedro, Amanda B. Spurdle

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Biallelic mutations in CDC20 cause female infertility due to oocyte maturation abnormality by Guangzhong Jiao, Jinhao Xing, Zhaoli Du, Hongchu Bao, Xiaoyan Liu

“…Our findings not only broaden the current understanding of CDC20 gene mutations but also profoundly illuminate how these mutations serve as potential genetic mechanisms underlying the arrest of oocyte maturation.…”
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A Case Report of Clinical Features Analysis of a Novel IKBKG Variant Leading to Anhidrotic Ectodermal Dysplasia and Immunodeficiency by HUANG Xiaomei, LUO Ying, HE Tingyan, XU Yongbin, XIA Yu, YANG Zhi, ZHU Xiaona, HUANG Yanyan, WENG Ruohang, YANG Jun, WANG Linlin

“…These symptoms were consistent with the phenotype of EDA-ID. Genetic analysis revealed a hemizygous mutation c.1249T > G (p.Cys417Gly) in exon 10 of the IKBKG gene in the patient. …”
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Hereditary neuropathy with liability to pressure palsies: a case series report by S. Naudžiūnaitė, R. Bunevičiūtė, B. Burnytė

“…All patients had a genetically proven diagnosis of a deletion at 17p12 locus, which contains PMP22 gene. …”
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A Comprehensive Review of the Diversity of Fungal Secondary Metabolites and Their Emerging Applications in Healthcare and Environment by Khushbu Wadhwa, Neha Kapoor, Hardeep Kaur, Eman A. Abu-Seer, Mohd. Tariq, Sazada Siddiqui, Virendra Kumar Yadav, Parwiz Niazi, Pankaj Kumar, Saad Alghamdi

“…Here, the authors have reviewed the recent advancements in genetic engineering, metabolic pathway manipulation, and synthetic biology to improve the production and yield of these SMs. …”
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Multivariable Discriminant Analysis for the Differential Diagnosis of Microcytic Anemia by Eloísa Urrechaga, Urko Aguirre, Silvia Izquierdo

“…Linear discriminant functions based on hemogram data can aid in differentiating between IDA and thalassemia, so samples can be efficiently selected for further analysis to confirm the presence of genetic anemia.…”
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Novel IL2RG gene mutation causing primary combined immunodeficiency disease: A case report and literature review by Fang Cao, Yingyu Shi, Fang Deng, Yu Yan

“…This case report not only enhances our understanding of CID but also provides a new addition to the genetic landscape of CID both domestically and internationally, aiding in earlier diagnosis and treatment of such diseases in clinical practice. …”
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Case report: Cerebrotendinous Xanthomatosis masquerading as adult ADHD in psychiatric practice by Jongtae Kim, Yun Jeong Hong, Si Baek Lee, Seong Hoon Kim, Myung Ah Lee, Eunbuel Ko, Jeong Wook Park

“…Comprehensive neurological assessments, including neuroimaging and genetic testing, ultimately diagnosed him with CTX. …”
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Functional Properties of Human Stem Cell-Derived Neurons in Health and Disease by Jason P. Weick

“…These include new technologies such as direct conversion of somatic cell types into neurons and glia which may accelerate maturation and retain genetic hallmarks of aging. In addition, novel forms of genetic manipulations have brought human stem cells nearly on par with those of rodent with respect to gene targeting. …”
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A Real-Time Train Timetable Rescheduling Method Based on Deep Learning for Metro Systems Energy Optimization under Random Disturbances by Jinlin Liao, Feng Zhang, Shiwen Zhang, Cheng Gong

“…This paper proposes a Modified Genetic Algorithm-Gate Recurrent Unit (MGA-GRU) method, which is a real-time TTR method based on deep learning. …”
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