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8521
New pneumococcal serotype 20C is a WciG O-acetyltransferase deficient variant of canonical serotype 20B
Published 2025-01-01“…Our findings highlight how pneumococci can alter their capsule PS structure and immunological characteristics through minor genetic modifications. Since the appearance of new capsule types can directly affect pneumococcal conjugate vaccine (PCV) implementation, a deeper understanding of capsule PS at the genetic, immunological, and biochemical levels is critical for the development of future diagnostic tools and vaccines.…”
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8522
Whole-genome sequencing and phylogenetic analysis of Salmonella isolated from pullets through final raw product in the processing plant of a conventional broiler complex: a longitu...
Published 2025-02-01“…Phylogenetic analysis showed strong genetic relationship among bacterial strains isolated from different stages. …”
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Intraspecific variation for heat stress tolerance in wild emmer-derived durum wheat populations
Published 2025-01-01“…The objective was to investigate the intraspecific genetic variation in wild emmer and identify traits associated with heat stress tolerance. …”
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8533
Association between sedentary behavior, physical activity, and osteoarthritis: results from NHANES 2007–2020 and Mendelian randomization analysis
Published 2025-01-01“…Additionally, MR was utilized to infer the genetic causality between SB, PA, and OA risk, using genetic instruments as proxies for SB and PA.ResultsThe final analysis, which included 24,738 participants, revealed that OA prevalence was 13.47%, with individuals diagnosed with OA exhibiting significantly higher levels of SB and lower levels of PA. …”
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8534
Results of Selective Biochemical Screening for Lysosomal Acid Lipase Deficiency and Sequencing of the <i>LIPA</i> Gene in the Risk Group Patients
Published 2025-02-01“…In 100 % of detected cases, genetic mutations in the LIPA gene included single nucleotide substitution c.894G>A. …”
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8535
Genome-wide analysis in northern Chinese twins identifies twelve new susceptibility loci for pulmonary function
Published 2024-12-01“…Abstract Background Previous genome-wide association studies (GWAS) have established association between genetic variants and pulmonary function across various ethnics, whereas such associations are scarcely reported in Chinese adults. …”
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Inflammatory bowel disease induced by bimekizumab
Published 2022-05-01“…Inflammatory bowel disease (IBD) is a chronic condition of the gastrointestinal tract, with a complex aetiopathogenesis in which genetic, immunological, and environmental factors are being discussed. …”
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ASSESSMENT OF IMPORTANT TECHNOLOGICAL PARAMETERS OF NEW MOROCCAN DOMESTICATED TETRAPLOID OAT LINES OF AVENA MAGNA
Published 2018-06-01“…Vavilov All-Russian Institute of Plant Genetic Resources are presented. Field and Nine tetraploid oat lines of Avena magna Murph. et Terr. were assessed for their technological performance. …”
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Escherichia Coli: From Genome Sequences to Consequence
Published 2006-01-01“…Professor Pallen's lecture, entitled 'Escherichia coli: From genome sequences to consequences', provides a summary of the important discoveries of his team of research scientists in the area of genetic sequencing and variations in phenotypic expression.…”
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Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient
Published 2025-02-01“…Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to multifactors and genetic polymorphisms. Here, we derived an induced pluripotent stem cell (hiPSC) line NTUHi006-A from a phenotype A (full-blown) PCOS patients with clinical hyperandrogenism, chronic anovulation, and polycystic ovarian morphology on ultrasonography. …”
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8540
Association between Neurofibromatosis Type 1 and Breast Cancer: A Report of Two Cases with a Review of the Literature
Published 2015-01-01“…Neurofibromatosis type 1 (NF1) is one of the most common genetic diseases in humans and is associated with various benign and malignant tumors, including breast cancer. …”
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