Genetic association of lipid and lipid-lowing drug targets with uterine fibroids by Mei Wu, Qiannan Lin, Siyu Li, Huiyan Wang, Wenbo Zhou

“…Conclusions: Our study provides evidence that HDL-C and TG levels were causally associated with UF risk. Genetically proxied CETP inhibition may have a protective effect against UF, which warrants further investigation.…”
Get full text

Environmental and Genetic Variables Influencing Mitochondrial Health and Parkinson’s Disease Penetrance by Alessandra Zanon, Peter P. Pramstaller, Andrew A. Hicks, Irene Pichler

“…The identification and validation of such modifiers leading to reduced penetrance or increased susceptibility in the case of heterozygous carriers of recessive mutations are relevant for a better understanding of mechanisms contributing to disease onset. We discuss genetic and environmental factors as well as mitochondrial DNA alterations and protein-protein interactions, all involved in mitochondrial function, as potential causes to modify penetrance of mutations in dominant PD genes and to determine manifestation of heterozygous mutations in recessive PD genes.…”
Get full text

Pathogenic and Genetic Characteristics of Helicobacter Pylori, and its Relationship with Drug-Resistance by Nilgün Uyduran Ünal, Adnan Barutçu, Toğrul Nagiyev, Mehmet Ağın, Tülay Kandemir, Oğuz Üsküdar, Figen Doran, Fatih Köksal, Gökhan Tümgör

Subjects: Get full text

Unraveling the Genetic Heartbeat: Decoding Cardiac Involvement in Duchenne Muscular Dystrophy by Valeria Novelli, Francesco Canonico, Renzo Laborante, Martina Manzoni, Alessandra Arcudi, Giulio Pompilio, Eugenio Mercuri, Giuseppe Patti, Domenico D’Amario

Subjects: Get full text

A Hybrid Genetic Algorithm for Satellite Image Downlink Scheduling Problem by Bingyu Song, Feng Yao, Yuning Chen, Yingguo Chen, Yingwu Chen

“…A schedule generation algorithm (SGA) is proposed to assign the downlink time window for each scheduled request according to a given request permutation. A hybrid genetic algorithm (HGA) combined with neighborhood search is proposed to optimize the downlink request permutation with the purpose of maximizing the utility function. …”
Get full text

Identification and analysis of individuals who deviate from their genetically-predicted phenotype. by Gareth Hawkes, Loic Yengo, Sailaja Vedantam, Eirini Marouli, Robin N Beaumont, GIANT Consortium, Jessica Tyrrell, Michael N Weedon, Joel Hirschhorn, Timothy M Frayling, Andrew R Wood

“…PLoS Genetics…”
Get full text

Genetic Profile and Associated Characteristics of 150 Korean Patients with Retinitis Pigmentosa by You Na Kim, Yoon Jeon Kim, Chang Ahn Seol, Eul-Ju Seo, Joo Yong Lee, Young Hee Yoon

“…Delineating clinical characteristics according to genetic variations may help clinicians identify subtype features and predict the clinical course of RP.…”
Get full text

Genetic Variations and mRNA Expression of NRF2 in Parkinson’s Disease by Caroline Ran, Karin Wirdefeldt, Lovisa Brodin, Mehrafarin Ramezani, Marie Westerlund, Fengqing Xiang, Anna Anvret, Thomas Willows, Olof Sydow, Anders Johansson, Dagmar Galter, Per Svenningsson, Andrea Carmine Belin

“…We have investigated the association between NRF2 and Parkinson’s disease in a Swedish case-control material and whether NRF2 expression levels correlate with NRF2 genetic variants, disease, or disease onset. Using pyrosequencing, we genotyped one intronic and three promoter variants in 504 patients and 509 control subjects from Stockholm. …”
Get full text

GENETIC DIVERSITY OF BREAD WHEAT LANDRACES COLLECTED BY SCIENTIFIC EXPEDITIONS IN AFGHANISTAN by O. P. Mitrofanova, P. P. Strelchenko, E. V. Zuev, K. Street, J. Konopka, M. Mackay

Subjects: Get full text

Identification of Genetic Biomarkers for Diagnosis of Myocardial Infarction Compared with Angina Patients by Yuanyuan Zhang, Chunyang Tian, Xuejian Liu, He Zhang

Get full text

Pea (Pisum sativum L.): the uneasy fate of the first genetical object by O. E. Kosterin

Subjects: Get full text

The problems of genetic support of dividing the black kite (Milvus migrans) into subspecies by N. G. Andreyenkova, I. J. Starikov, M. Wink, I. V. Karyakin, O. V. Andreyenkov, I. F. Zhimulev

“…Recently, studies of genetic differences between black kite populations started to emerge. …”
Get full text

Genetic screening strategy for children with hereditary spherocytosis in Jiangxi Province of China by Chongjun Wu, Chongjun Wu, Zhongjin Xu, Zhongjin Xu, Qian Wan, Qian Wan, Feng Chen, Feng Chen, Yao Ye, Yao Ye, Hong Wang, Hong Wang

Subjects: “…genetic screening strategy…”
Get full text

Genetic Polymorphisms of IL17 and Chagas Disease in the South and Southeast of Brazil by Pâmela Guimarães Reis, Christiane Maria Ayo, Luiz Carlos de Mattos, Cinara de Cássia Brandão de Mattos, Karina Mayumi Sakita, Amarilis Giaretta de Moraes, Larissa Pires Muller, Julimary Suematsu Aquino, Luciana Conci Macedo, Priscila Saamara Mazini, Ana Maria Sell, Divina Seila de Oliveira Marques, Reinaldo Bulgarelli Bestetti, Jeane Eliete Laguila Visentainer

“…The aim of this study was to investigate possible associations between genetic polymorphisms of IL17A G197A (rs2275913) and IL17F T7488C (rs763780) with Chagas Disease (CD) and/or the severity of left ventricular systolic dysfunction (LVSD) in patients with chronic Chagas cardiomyopathy (CCC). …”
Get full text

Molecular epidemiology and genetic diversity of disappearing Plasmodium vivax in southern Thailand by Parsakorn Tapaopong, Gustavo da Silva, Aurel Holzschuh, Wasinee Rungsarityotin, Chayanut Suansomjit, Kanit Pumchuea, Khajohnpong Manopwisedjaroen, Amnat Khamsiriwatchara, Podjadeach Khuntong, Liwang Cui, Cristian Koepfli, Jetsumon Sattabongkot, Wang Nguitragool

Subjects: Get full text

Improved Genetic Algorithm to Solve the Scheduling Problem of College English Courses by Jing Xu

“…Research shows that the improved genetic algorithm has improved average fitness value and time compared with traditional genetic algorithm. …”
Get full text

A Biopsychosocial Overview of Speech Disorders: Neuroanatomical, Genetic, and Environmental Insights by Diya Jaishankar, Tanvi Raghuram, Bhuvanesh Kumar Raju, Divyanka Swarna, Shriya Parekh, Narendra Chirmule, Vikramsingh Gujar

Subjects: Get full text

Population genetic analysis of clinical Mycobacterium abscessus complex strains in China by Xiangchen Li, Xiangchen Li, Yelei Zhu, Yewei Lu, Kunyang Wu, Yang Che, Xiaomeng Wang, Weixin Wang, Junli Gao, Junshun Gao, Zhengwei Liu, Zhengwei Liu, Zhuxian Zhou

Subjects: Get full text

Optimal planning of optical transmission network using improved genetic algorithm by Yue SHI, song QIUXue, yong GUOShao, Feng QI

Subjects: Get full text

An Improved Genetic-Shuffled Frog-Leaping Algorithm for Permutation Flowshop Scheduling by Peiliang Wu, Qingyu Yang, Wenbai Chen, Bingyi Mao, Hongnian Yu

“…This paper proposes an improved genetic-shuffled frog-leaping algorithm (IGSFLA) to solve the permutation flowshop scheduling problem. …”
Get full text