A new effLuc/Kate dual reporter allele for tumor imaging in mice by Latifa Bakiri, Mélanie Tichet, Carolina Marques, Martin K. Thomsen, Elizabeth A. Allen, Stefanie Stolzlechner, Ke Cheng, Kazuhiko Matsuoka, Massimo Squatrito, Douglas Hanahan, Erwin F. Wagner

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Pivotal roles of melanopsin containing retinal ganglion cells in pupillary light reflex in photopic conditions by Jeremy Matthew Bohl, Abdul Rhman Hassan, Zachary J. Sharpe, Megi Kola, Angela Shehu, Deborah Langrill Beaudoin, Tomomi Ichinose

“…Previous studies have investigated the roles of photoreceptors and ipRGCs in PLR using genetically-modified mouse models. Herein, we acutely ablated photoreceptors using N-nitroso-N-methylurea (MNU) to examine the roles of ipRGCs in the PLR. …”
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Physiological premature aging of ovarian blood vessels leads to decline in fertility in middle-aged mice by Lu Mu, Ge Wang, Xuebing Yang, Jing Liang, Huan Tong, Lingyu Li, Kaiying Geng, Yingnan Bo, Xindi Hu, Ruobing Yang, Xueqiang Xu, Yan Zhang, Hua Zhang

“…This leads to a diminished blood supply to the ovaries, resulting in inadequate development and maturation of ovarian follicles. Utilizing genetic-modified mouse models, we demonstrate that granulosa cell secreted VEGFA governs ovarian angiogenesis, but the physiological decline in oBV is not attributed to VEGFA insufficiency. …”
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