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Manipulations with early mouse embryos for generation of genetically modified animals
Published 2017-12-01Get full text
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Interactions between Serum Adipokines and Osteocalcin in Older Patients with Hip Fracture
Published 2012-01-01“…Experiments on genetically modified animals have discovered a complex cross-regulation between adipokines (leptin, adiponectin) and osteocalcin. …”
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A REVIEW ON RECENT ADVANCES IN ANIMAL BIOTECHNOLOGY
Published 2023-09-01“…Biopharming utilizes genetically modified animals for large-scale pharmaceutical production, balancing potential benefits with containment and safety issues. …”
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Gene function revealed at the moment of stochastic gene silencing
Published 2025-01-01“…Analysis of real data demonstrates that scSGS can reveal regulatory relationships up- and downstream of target genes, circumventing the survivorship bias that often affects gene knockout and perturbation studies. scSGS thus offers an efficient approach for gene function prediction, with significant potential to reduce the use of genetically modified animals in gene function research.…”
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CDK14 regulates the development and repair of lung
Published 2025-01-01“…However, the function of CDK14 during organ development and regeneration has not been investigated in genetically-modified animals. Here, we found that genetic ablation of Cdk14 influenced pulmonary vascular endothelial cells and alveolar epithelial cells during mice embryonic development as well as repair of lung after bleomycin or lipopolysaccharide induced injury. …”
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