Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes by Xuebao Zhang, Kezhong Zhang

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Clinical Insight into Congenital Hypothyroidism Among Children by Hüseyin Anıl Korkmaz

“…Molecular, genetic, and technological advances have led to increased knowledge regarding neonatal thyroid hormone metabolism disorders. …”
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Characteristics of primary biliary cirrhosis in British Columbia's First Nations population by Laura Arbour, Rosemarie Rupps, Leigh Field, Paul Ross, Anders Erikson, Harvey Henderson, Warren Hill, Eric M Yoshida

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Transcript Profiles of Stria Vascularis in Models of Waardenburg Syndrome by Linjun Chen, Lin Wang, Lei Chen, Fangyuan Wang, Fei Ji, Wei Sun, Hui Zhao, Weiju Han, Shiming Yang

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The frequency of distribution of the genotypes of the IL4 polymorphism (rs 2243250) in psoriasis and psoriatic arthritis by A. A. Barilo, M. V. Smolnikova, S. V. Smirnova

“…Psoriasis (PS) and psoriatic arthritis (PsA) are multifactorial diseases determined by the result of complex combined interaction of genetic and environmental factors. The study of genetic polymorphism of PS and PsA will allow identification of common diagnostic criteria for the progression of pathology. …”
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Diabetes and congenital malformations. Cienfuegos, 2005-2015 by Oramis Isabel Padrón Aguilera, Maylé Santos Solí, Vivian Rosa Vázquez Martínez, Cristóbal Jorge Torres González, Gladys Bárbara Barberis Pérez

“…<strong>Foundation:</strong> diabetes is the metabolic disorder with the greatest impact on maternal health and its offspring, with greater emphasis on congenital malformations.…”
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Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions by Jai Ahuja, Luba Leontieva

“…The report delves into the patient’s complex background, including psychosocial stressors, genetic predisposition to depression, and a history of personality traits that may have influenced her response to ketamine. …”
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SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors by Raymond Cespuglio, Anna Gorlova, Konstantin Zabegalov, Kirill Chaprov, Evgeniy Svirin, Kseniia Sitdikova, Alisa Burova, Boris Shulgin, Ksenia Lebedeva, Alexei V. Deikin, Sergey Morozov, Tatyana Strekalova

“…Background: The inheritance of the short SLC6A4 allele, encoding the serotonin transporter (SERT) in humans, increases susceptibility to neuropsychiatric and metabolic disorders, with aging and female sex further exacerbating these conditions. …”
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Just a SNP away: The future of in vivo massively parallel reporter assay by Katherine N. Degner, Jessica L. Bell, Sean D. Jones, Hyejung Won

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A Comprehensive Review of Zavegepant as Abortive Treatment for Migraine by Nazir Noor, Alexis Angelette, Abby Lawson, Anjana Patel, Ivan Urits, Omar Viswanath, Cyrus Yazdi, Alan D. Kaye

“…Migraine headache is a widespread and complex neurobiological disorder that is characterized by unilateral headaches that are often accompanied by photophobia and phonophobia. …”
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Potential Biomarkers of the Earliest Clinical Stages of Parkinson’s Disease by Anelya Kh. Alieva, Elena V. Filatova, Aleksey V. Karabanov, Sergey N. Illarioshkin, Petr A. Slominsky, Maria I. Shadrina

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RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models by Yingqi Lin, Caijuan Li, Yizhi Chen, Jiale Gao, Jiawei Li, Chunhui Huang, Zhaoming Liu, Wei Wang, Xiao Zheng, Xichen Song, Jianhao Wu, Jiaxi Wu, Oscar Junhong Luo, Zhuchi Tu, Shihua Li, Xiao-Jiang Li, Liangxue Lai, Sen Yan

“…Furthermore, the success of this approach provides valuable insights and novel avenues for the treatment of other genetic disorders caused by gene mutations.…”
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Novel Haplotype Indicator for End-Stage Renal Disease Progression among Saudi Patients by Cyril Cyrus, Shahanas Chathoth, Chittibabu Vatte, Nafie Alrubaish, Othman Almuhanna, J. Francis Borgio, Samir Al-Mueilo, Fahd Al Muhanna, Amein K. Al Ali

“…There are strong heritable components in the manifestation of the disease with a genetic predisposition to renal disorders, including focal segmental glomerulosclerosis and arterionephrosclerosis. …”
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Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain by Han-Chung Lee, Kai-Leng Tan, Pike-See Cheah, King-Hwa Ling

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Arginine-Restricted Therapy Resistant Bilateral Macular Edema Associated with Gyrate Atrophy by Sibel Doguizi, Mehmet Ali Sekeroglu, Mustafa Alpaslan Anayol, Pelin Yilmazbas

“…Gyrate atrophy is a rare genetical metabolic disorder affecting vision. Here, we report a 9-year-old boy with gyrate atrophy associated with bilateral macular edema at the time of diagnosis and the effect of long term metabolic control on macular edema. …”
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Co-expression of glutamatergic and autism-related genes in the hippocampus of male mice with disturbances of social behavior by I. L. Kovalenko, A. G. Galyamina, D. A. Smagin, N. N. Kudryavtseva

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The Role of the Endothelin System in the Vascular Dysregulation Involved in Retinitis Pigmentosa by Francesco Saverio Sorrentino, Claudio Bonifazzi, Paolo Perri

“…Retinitis pigmentosa is a clinical and genetic group of inherited retinal disorders characterized by alterations of photoreceptors and retinal pigment epithelium leading to a progressive concentric visual field restriction, which may bring about severe central vision impairment. …”
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Systematic dissection of pleiotropic loci and critical regulons in excitatory neurons and microglia relevant to neuropsychiatric and ocular diseases by Yunlong Ma, Dingping Jiang, Jingjing Li, Gongwei Zheng, Yao Deng, Xuanxuan Gou, Shuaishuai Gao, Cheng Chen, Yijun Zhou, Yaru Zhang, Chunyu Deng, Yinghao Yao, Haijun Han, Jianzhong Su

“…In sum, these findings underscore the genetic link between psychiatric disorders and ocular diseases.…”
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PPAR𝛾, PTEN, and the Fight against Cancer by Rosemary E. Teresi, Kristin A. Waite

“…Indeed, several in vivo studies have demonstrated that genetic alterations of PPAR𝛾 can promote tumor progression. …”
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Chronic Myeloid Leukemia Relapsing 25 Years after Allogenic Stem Cell Transplantation by Håkon Reikvam, Jørn Skavland, Stein-Erik Gullaksen, Randi Hovland, Tobias Gedde-Dahl, Øystein Bruserud, Bjørn Tore Gjertsen

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