Gene Therapy Approaches by Ahmed Jumaa Ahmed, Hogir Saadi

“… Gene therapy can be described broadly as the transfer of genetic material to control a disease or at least to enhance a patient's clinical status. …”
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Gene Therapy for Parkinson's Disease by Rachel Denyer, Michael R. Douglas

“…Novel approaches based on gene therapy have several potential advantages over conventional treatment modalities. …”
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Gene Therapy for Glioblastoma Multiforme by Smit Shah, Joshua Green, Shantelle A. Graff, Qi Li, John D. Heiss

“…The possible benefits of combining gene therapy with standard GBM treatments will also be covered.…”
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Targeting Herpetic Keratitis by Gene Therapy by Hossein Mostafa Elbadawy, Marine Gailledrat, Carole Desseaux, Diego Ponzin, Stefano Ferrari

“…Ocular gene therapy is rapidly becoming a reality. By November 2012, approximately 28 clinical trials were approved to assess novel gene therapy agents. …”
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Genetic Hearing Loss and Gene Therapy by Nathanial T Carpena, Min Young Lee

Subjects: “…gene therapy…”
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Gene Therapy for HIV Infections: Intracellular Immunization by Alain Piché

“…Current understanding of HIV molecular biology and pathogenesis has opened the way for the development of gene therapy strategies for HIV infections. In this context, a number of intracellular immunization-based strategies have been evaluated, and some of them have reached the stage of phase I/II human clinical trials. …”
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Advances in Gene Therapy for Neurologic Disorders: An Overview by Pallavi Chand, K. Trideva Sastri, Ashish Singh Chauhan, Souvik Chakraborty, Vikash Jakhmola

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Plasmid Gene Therapy for Monogenic Disorders: Challenges and Perspectives by Marco A. Luís, Marcelo A. D. Goes, Fátima Milhano Santos, Joana Mesquita, Paulo Tavares-Ratado, Cândida Teixeira Tomaz

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Influential Factors and Synergies for Radiation-Gene Therapy on Cancer by Mei Lin, Junxing Huang, Yujuan Shi, Yanhong Xiao, Ting Guo

“…This review provides the main influential factors to radiation-gene therapy on cancer and the synergistic techniques to improve the anticancer effect of radiation-gene therapy.…”
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Intricacies for Posttranslational Tumor-Targeted Cytokine Gene Therapy by Jeffry Cutrera, Denada Dibra, Arun Satelli, Xuexing Xia, Shulin Li

“…These interesting and sometimes contrasting results highlight both the efficacy and personalization of tumor-targeted cytokine gene therapies while exposing important aspects of these same therapies which must be considered before progressing into approved treatment options.…”
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Improving TCR Gene Therapy for Treatment of Haematological Malignancies by Emma Nicholson, Sara Ghorashian, Hans Stauss

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Advancements in the Treatment of Mucopolysaccharidoses: From Established Therapies to Gene Therapy by Joanna Wanat, Wojciech Homa, Aleksandra Warunek, Gabriela Gronowicz, Izabela Dzikowska, Agata Siejka, Daria Stefaniak, Weronika Zielińska, Michał Chról

Subjects: “…Gene therapy…”
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Current AAV-mediated gene therapy in sensorineural hearing loss by Jieyu Qi, Xiaolong Fu, Liyan Zhang, Fangzhi Tan, Nianci Li, Qiuhan Sun, Xiaojie Hu, Zuhong He, Ming Xia, Renjie Chai

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The Potential Use of the CRISPR-Cas System for HIV-1 Gene Therapy by Gabriela De Nardi Sanches-da-Silva, Luiza Fonseca Sales Medeiros, Fabio Mitsuo Lima

“…The objective of this minireview is to synthesize the current knowledge on the application of CRISPR-Cas-based gene therapy for HIV-1. The strategies encompass all steps of the viral infection cycle, from inhibition of cell invasion, through viral replication and integration inhibition, to excision of the latent provirus. …”
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Heparanase, A Key Target for Gene Therapy against Human Malignancies by Youlei Zhang, Yi Wang, Zhiren Fu, Feng Shen

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Clinical trials to gene therapy development and production in Brazil: a review by Jonas Alex Morales Saute, Virginia Picanço-Castro, Ana Carolina de Freitas Lopes, João Batista da Silva Júnior, Johanna Henriques Nehm, Franciele dos Santos Maciel, Ida Vanessa Doederlein Schwartz, Juliana Maria Ferraz Sallum, Margareth Castro Ozelo, Roberto Giugliani, Martin Bonamino, Hilda Petrs-Silva, Guilherme Baldo

Subjects: “…Gene therapy products…”
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Adeno-associated virus-based gene therapy for hemophilia–addressing the gaps by Wolfgang Miesbach, Paul Batty, Pratima Chowdary, Sylvia Fong, Radoslaw Kaczmarek, Frank W.G. Leebeek, Brian Long, Johnny Mahlangu, Mike Makris, Glenn F. Pierce, Steven W. Pipe, Alok Srivastava, Jan Voorberg, Flora Peyvandi

Subjects: “…gene therapy…”
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Novel Interventional Approaches for ALI/ARDS: Cell-Based Gene Therapy by Ying-Gang Zhu, Jie-Ming Qu, Jing Zhang, Hong-Ni Jiang, Jin-Fu Xu

“…Recently, the combination of cell and gene therapy which has been demonstrated to provide additive benefit has opened up a new chapter in therapeutic strategy and provides a basis for the development of an innovative approach for the prevention and treatment of ALI/ARDS.…”
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Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside by Rajeshwari D. Koilkonda, John Guy

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Critical Aspects of Clinical Trial Design for Novel Cell and Gene Therapies by Zinovia Kefalopoulou, Iciar Aviles-Olmos, Thomas Foltynie

“…Neural cell transplantation and gene therapy have attracted considerable interest as promising therapeutic alternatives for patients with Parkinson's disease (PD). …”
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