The Clinical Impact of Tumor Grade Heterogeneity in Nonmuscle- invasive Urothelial Carcinoma of the Bladder by Meftun Culpan, Ferhat Keser, Ayberk İplikci, Gözde Kır, Gökhan Atış, Asif Yıldırım

“…Our results should be verified by future studies.…”
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Effect of conservative treatment on greater trochanteric pain syndrome: a systematic review and network meta-analysis of randomized controlled trials by Si-Qi Wang, Ning-Yi Guo, Wei Liu, Hong-jie Huang, Bing-bing Xu, Jian-quan Wang

“…Owing to the limited number of included studies, comparing the effects of different conservative treatments remains challenging. Future studies should expand the quantity of RCTs to identify the optimal conservative treatment strategy for GTPS. …”
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Research Progress of Nerve Mobilization in Basic and Clinical Rehabilitation by Shuo LUAN, Quanshou LING, Miaoshang ZENG, Anni LIN, Yingping JIANG

“…Moreover, previous studies proved that peripheral mechanical loads applied to neural tissues could improve the central neural plasticity, and the improvements were observed in muscular tone, strength, body weight distribution, postural balance and other functional motor performances, which helped to attenuate the motor dysfunction of the upper and lower limbs. Future studies are necessary to validate the treatment frequency, treatment duration and movement sequence for varies diseases and physiopathological conditions. …”
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Weight Change and Predictors of Weight Change Among Patients Initiated on Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide or Bictegravir/Emtricitabine/Tenofovir Alafenamid... by Bruno Emond, Carmine Rossi, Aurélie Côté-Sergent, Keith Dunn, Patrick Lefebvre, Marie-Hélène Lafeuille, Prina Donga

“…Weight gain is an important factor to consider when selecting antiretroviral regimens, since it is associated with long-term health consequences. Future studies with larger sample size and longer follow-up time are warranted.…”
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Prevalence of and factors associated with symptoms consistent with a diagnosis of irritable bowel syndrome among resident physicians in standardised training in China: a cross-sect... by Xin Wang, Ning Li, Xia Li, Zhigang Li, Jun Zhao, Xuefei Wang, Xin Hao, Jiayi Yang, Junjian Tian

“…Depression symptoms were significantly associated with IBS (unadjusted OR 0.498, 95% CI 0.265 to 0.935, p=0.030).Conclusion These findings suggest that IBS is common among resident physicians in standardised training. Future studies should investigate emotional distress, especially stress and depression, in the development of prevention or treatment of IBS.…”
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The Eagle Eyes: an Intervention Utilizing Visual Thinking Strategies to Enhance the Observation Skills of Medical Students by Najmeh Ghorbani, Maryam Alizadeh, Azadeh Sayarifard, Abdoljavad Khajavi, Philip Yenawine

“…This conclusion warrants further investigation in future studies.…”
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Longitudinal Assessment of Alterations in Peripheral Inflammatory Markers Over a Hospitalization Period in Patients with Schizophrenia by Süleyman Dönmezler, Oya Güçlü, İmren Kurt, Halil Ibrahim Ozturk

“…Conclusion: This study underscores the influence of regular antipsychotic treatment and hospital care in reducing inflammation markers like NLR, MLR, PLR, SII, and CAR in schizophrenia patients. Future studies should explore the potential of markers like CAR and SII in detecting low-grade inflammation, and further probe into the role of sleep, nutrition, and physical activity, emphasising the paramount role of comprehensive hospital care.…”
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Genetic variation reveals the therapeutic potential of BRSK2 in idiopathic pulmonary fibrosis by Zhe Chen, Mingyang Tang, Nan Wang, Jiangjiang Liu, Xiaoyan Tan, Haitao Ma, Jing Luo, Kai Xie

“…Conclusions BRSK2 is identified as a critical pathogenic factor in IPF, with strong potential as a therapeutic target. Future studies should focus on its translational implications and the development of targeted therapies to improve patient outcomes.…”
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Fatigue and recovery among Malaysian doctors: the role of work-related activities during non-work time by Mohd Fadhli Mohd Fauzi, Hanizah Mohd Yusoff, Nur Adibah Mat Saruan, Rosnawati Muhamad Robat, Mohd Rizal Abdul Manaf, Maisarah Ghazali

“…There is a need for future studies with design that allow causal inference to address these relationships.…”
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Identifying Digital Markers of Attention-Deficit/Hyperactivity Disorder (ADHD) in a Remote Monitoring Setting: Prospective Observational Study by Heet Sankesara, Hayley Denyer, Shaoxiong Sun, Qigang Deng, Yatharth Ranjan, Pauline Conde, Zulqarnain Rashid, Philip Asherson, Andrea Bilbow, Madeleine J Groom, Chris Hollis, Richard J B Dobson, Amos Folarin, Jonna Kuntsi

“…The participants with ADHD were (1) slower (PdPdPdPdPdPPdPdPdPdPd ConclusionsIn a novel exploration of digital markers of ADHD, we identified candidate digital signals of restlessness, inconsistent attention, and difficulties completing tasks. Larger future studies are needed to replicate these findings and to assess the potential of such objective digital signals for tracking ADHD severity or predicting outcomes.…”
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Tinnitus Suppression with Electrical Stimulation at the Most Basal Contact of the Cochlear Implant Electrode as a Model for Round Window Stimulation by Kiana Kheirkhah, Valerie Van Kelecom, Marc Leblans, Joost van Dinther, Glynnis De Greve, Erwin Offeciers, Andrzej Zarowsk

“…The long-term effects of this therapy should be confirmed in future studies.…”
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Risk factors for fear of falling in stroke patients: a systematic review and meta-analysis by Li Ma, Qi Xie, Juhong Pei, Ling Gou, Yabin Zhang, Juanping Zhong, Yujie Su, Xinglei Wang, Xinman Dou

“…Sensitivity analysis (leave-one-out method) showed that the pooled estimate was stable.Conclusion This meta-analysis indicated that female population, impaired balance ability, lower mobility, history of falls and walking aid in patients with stroke might be at greater risk for FoF. Future studies are recommended to determine other risk factors specific to patients with stroke.…”
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Asthma and obesity increase inflammatory markers in children by Harshita Shailesh, Safa Noor, Lena Hayati, Antonisamy Belavendra, Nicholas Van Panhuys, Abdul Badi Abou-Samra, Stefan Worgall, Ibrahim Janahi, Ibrahim Janahi

“…These findings challenge the previous view that obesity enhances inflammation in individuals with asthma and highlight the importance of considering both conditions while treating obesity-associated asthma in children. Future studies are necessary to further explore the mechanisms that link obesity and asthma in the pediatric population.…”
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The enlarged perivascular spaces in the hippocampus is associated with memory function in patients with type 2 diabetes mellitus by Peichun Pan, Dongsheng Zhang, Jing Li, Min Tang, Xuejiao Yan, Xin Zhang, Man Wang, Xiaoyan Lei, Xiaoling Zhang, Jie Gao

“…H-EPVS may serve as a potential neuroimaging biomarker for cognitive impairment in patients with T2DM, warranting further investigation and validation in future studies.…”
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Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results by Sutema IAMP, Latarissa IR, Widowati IGAR, Sartika CR, Ciptasari NWE, Lestari K

“…Probiotics presented a natural, effective alternative to conventional acne treatment. However, future studies are needed to determine optimal treatment protocols.Keywords: probiotics, skin microbiome, acne vulgaris, bacterial imbalance, inflammatory skin conditions…”
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Exploring the General Acceptability and User Experience of a Digital Therapeutic for Cognitive Training in a Singaporean Older Adult Population: Qualitative Study by Siong Peng Kwek, Qiao Ying Leong, V Vien Lee, Ni Yin Lau, Smrithi Vijayakumar, Wei Ying Ng, Bina Rai, Marlena Natalia Raczkowska, Christopher L Asplund, Alexandria Remus, Dean Ho

“…ConclusionsGiven the positive engagement and feedback obtained from Singaporean older adults on CURATE.DTx, this study can serve as a basis for future platform iterations and strategies that should be considered during implementation. Future studies should continue implementing an iterative codesign approach to ensure the broader applicability and effectiveness of interventions tailored to this demographic.…”
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Assessing awareness and treatment knowledge of preventable blindness in rural and urban South African communities by Z Kiva, J E Wolvaardt

“…Without this, there will be little demand for any treatment or service. Future studies are needed to understand which health promotion interventions are effective in preventable blindness in rural populations. …”
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The prognostic role of cardiac and inflammatory biomarkers in extubation failure in patients with COVID-19 acute respiratory distress syndrome by Carline N. L. Groenland, Adinde H. Siemers, Eric A. Dubois, Diederik Gommers, Leo Heunks, Evert-Jan Wils, Vivan J. M. Baggen, Henrik Endeman

“…Since Hs-TnT is the only biomarker that is independently associated with extubation failure, Hs-TnT could offer additional objective measures for assessing readiness for extubation. Future studies should focus on an integrative approach of biomarkers combined with relevant clinical factors to predict extubation failure.…”
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Effects of functional training on physical and technical performance among the athletic population: a systematic review and narrative synthesis by Wensheng Xiao, Te Bu, Junlong Zhang, Haogang Cai, Wuyi Zhu, Xiaorong Bai, Lin Zhang, Soh Kim Geok

“…However, no significant difference in the data was observed between the functional training groups and the regular training group, which may be due to the duration of the training program, the different training experiences of the athletes, and the different focuses of the training regimens. Therefore, future studies should focus on the physical and technical performance of different sports groups with different types and durations of functional training programs to expand the current evidence base.…”
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Exploring the Prognostic Role of Trop-2, CD47, and CD163 Expression Levels on Survival Outcomes in Patients with Triple-Negative Breast Cancer by Ramazan Oguz Yüceer, Sedanur Aydın, Iclal Gelir, Tulay Koc, Ersin Tuncer, Mahmut Ucar

“…These findings offer promising prospects for future studies on combined antibody–drug conjugates (ADCs), as they may present opportunities to address multiple resistance mechanisms in the management of TNBC and enhance clinical outcomes.…”
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