Molecular mechanisms of cis-oxygen bridge neonicotinoids to Apis mellifera Linnaeus chemosensory protein: Surface plasmon resonance, multiple spectroscopy techniques, and molecular... by Xiangshuai Li, Shiyu Li, Yang Liu, Li Cui, Daibin Yang, Shuning Chen, Xusheng Shao, Huizhu Yuan, Xiaojing Yan

“…Furthermore, this research enhances the understanding of the interaction mechanisms between cis-structured neonicotinoid substances and honeybee proteins, providing a foundation for future studies on the environmental safety of these compounds.…”
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Hormonal Influences on ADC Values in Breast Tissues: A Scoping Review of DWI in Pre- and Post-menopausal Women [version 2; peer review: 2 approved] by Neil Barnes Abraham, Abhimanyu Pradhan, Suresh Sukumar, Sneha Ravichandran, Winniecia Dkhar, Rajagopal Kadavigere

“…While DWI with ADC mapping shows promise as a reliable diagnostic tool across different hormonal states, further research is needed to fully understand and account for hormonal influences on ADC measurements. Future studies should focus on longitudinal designs, standardization of DWI protocols, and integration of hormonal status information into breast cancer risk assessment models.…”
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Lifestyle as Risk Factor for Infectious Causes of Death in Young Dogs: A Retrospective Study in Southern Italy (2015–2017) by Lorena Cardillo, Giuseppe Piegari, Valentina Iovane, Maurizio Viscardi, Flora Alfano, Anna Cerrone, Ugo Pagnini, Serena Montagnaro, Giorgio Galiero, Giuseppe Pisanelli, Giovanna Fusco

“…It lays the groundwork for future studies attempting to understand the circulation of infectious agents in a determined area.…”
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Thresholds of handgrip strength for all-cause mortality in patients with chronic kidney disease: a secondary systematic review with dose-response meta-analysis by Hao Chen, Fan Zhang, Liuyan Huang, Yan Bai, Yifei Zhong, Yi Li

“…After that, the risk of death increased slightly.Conclusion A U-shaped association exists between handgrip strength and all-cause mortality risk in CKD patients. Future studies with quantitative measurements for each CKD stage will help to determine precise relative risk estimates between handgrip strength and mortality risk in patients with different stages of CKD.…”
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Teaching healthy lifestyle behaviors based on philosophical thinking to preschool children: a randomized controlled trial by Zakieh Khoramaki, Mahin Nazari, Leila Ghahremani, Mohammad Hossein Kaveh, Abdolrahim Asadollahi

“…The results were more pronounced in children than in their parents. Future studies should focus on longer interventions and explore the effects across different age groups. …”
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Digital Twins and Enabling Technology Applications in Mining: Research Trends, Opportunities, and Challenges by Mihiran Galagedarage Don, Thumeera R. Wanasinghe, Raymond G. Gosine, Peter J. Warrian

“…Over the past five years, both have significantly increased their research contributions, presenting various opportunities and challenges to inspire future studies.…”
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Which variables are associated with recruitment failure? A nationwide review on obstetrical and gynaecological multicentre RCTs (2003–2023) by Ben W Mol, Madelon van Wely, L Ramos, J J Duvekot, J B Derks, Fulco van der Veen, Ruben Duijnhoven, H J van Beekhuizen, M J E Mourits, J A M van der Post, E Pajkrt, M A Oudijk, H C J Scheepers, Mariette Goddijn, J Huirne, Marijke C van der Weide, A Kwee, C Willekes, M Y Bongers, Judith Rikken, Romee Casteleijn, S Middeldorp, I M Custers, M P Lambregtse – van den Berg, V Mijatovic, F J M Broekmans, A Hoek, J P de Bruin, M H Mochtar, S Mastenbroek, J P W R Roovers, F Mol, A Vollebregt, C H van der Vaart, K B Kluivers, M E Vierhout, R C Painter, P M A J Geomini

“…Awareness of these variables is important when designing future studies.…”
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RNA Virus Discovery Sheds Light on the Virome of a Major Vineyard Pest, the European Grapevine Moth (<i>Lobesia botrana</i>) by Humberto Debat, Sebastian Gomez-Talquenca, Nicolas Bejerman

“…These results underscore the existence of a complex virome within <i>L. botrana</i> and lay the foundation for future studies investigating the ecological roles, evolutionary dynamics, and potential biocontrol applications of these viruses in the <i>L. botrana</i>–vineyard ecosystem.…”
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Definition of sinonasal and otological exacerbation in patients with primary ciliary dyskinesia: an expert consensus by Myrofora Goutaki, Yin Ting Lam, Andreas Anagiotos, Miguel Armengot, Andrea Burgess, Raewyn Campbell, Mathilde Carlier, Nathalie Caversaccio, Neil K. Chadha, Berat Demir, Sinan Ahmed D. Dheyauldeen, Onder Gunaydin, Amanda Harris, Isolde Hayn, Deniz Inal-Ince, Eric Levi, Trini Lopez Fernandez, Jane S. Lucas, Bernard Maitre, Anne-Lise M.L. Poirrier, Lynne Schofield, Kazuhiko Takeuchi, Christine van Gogh, Nikolaus E. Wolter, Jean-François Papon

“…They should be validated in future studies and trials together with other potential outcomes, to assess their usability.…”
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The relationship between prenatal drought exposure and the diversity and composition of gut microbiome in pregnant women and neonates by Qingbo Fang, Tianlai Qiu, Fenglan Chen, Xuqi Tian, Zijun Feng, Yanan Cao, Jinbing Bai, Jing Huang, Yanqun Liu

“…This study identified that prenatal SPEI levels were correlated with specific maternal and neonatal gut microbial taxa, as well as neonatal gut microbial functional pathways. Future studies should further investigate the mechanisms by which drought exposure influences maternal and neonatal gut microbial diversities, composition, and functional pathways.…”
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A Hybrid Efficient U-Net Framework for Detection of Anterior Belly of the Digastric Muscle on Ultrasonography by Sule Erdem, Suheda Erdem, Muammer Turkoglu, Abdulkadir Sengur, Nebras M. Sobahi

“…The model can contribute to clinical diagnostic processes with its ability to accurately detect small and large structures. Future studies can increase the generalization capacity of the model by testing it in different modalities.…”
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Low-Frequency Repetitive Transcranial Magnetic Stimulation for Stroke-Induced Upper Limb Motor Deficit: A Meta-Analysis by Lan Zhang, Guoqiang Xing, Shiquan Shuai, Zhiwei Guo, Huaping Chen, Morgan A. McClure, Xiaojuan Chen, Qiwen Mu

“…LF-rTMS as an add-on therapy significantly improved upper limb functional recovery especially the hand after stroke, probably through rebalanced cortical excitability of both hemispheres. Future studies should determine if LF-rTMS alone or in conjunction with practice/training would be more effective. …”
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Wheat Leaf Rust Effector Pt48115 Localized in the Chloroplasts and Suppressed Wheat Immunity by Lulu Song, Liping Cui, Hao Li, Na Zhang, Wenxiang Yang

“…Our findings lay a foundation for future studies on the pathogenesis of <i>Pt</i> during wheat–fungus interaction.…”
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Boron isotopes fractionation and its application progress in groundwater research by Chenbo LEI, Huaming GUO, Shiping XING

“…B isotopes can also be utilized to trace hydrogeochemical processes associated with the enrichment of fluoride and arsenic, thereby enhancing the knowledge of the formation mechanism of high fluoride and arsenic groundwater. The future studies on groundwater B isotopes should focus on: (1) Supplementing B-isotope techniques with water chemistry and other isotope techniques to quantify contributions of different hydrogeochemical processes to of the specific solute transformation. (2) Long-term monitoring of B isotopes in areas with high B geothermal water and natural inferior groundwater to determine B endmembers in different conditions and to quantitively assess the negative impact of hazardous components on environment. …”
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Experiences of working as a clinical nurse while pregnant during the coronavirus disease-2019 pandemic: a qualitative study by Lin Ye Wu, Wing Fai Yeung, Yao Lin Pei, Ling Xi Chen, Meng Qi Li, Jia Yin Ruan

“…Managers, occupational health and other health system leaders, and policymakers should be aware of the importance of establishing a work environment that guarantees safe continued pregnancy. Future studies should focus on the establishment of specific guidelines and manuals regarding how pregnant nurses worked, as well as the development of self-protection interventions during pregnancy. …”
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Comparative Effectiveness of Anti-Inflammatory Drug Treatments in Coronary Heart Disease Patients: A Systematic Review and Network Meta-Analysis by Ivan Wudexi, Elica Shokri, Mohamed Abo-Aly, Kazuhiro Shindo, Ahmed Abdel-Latif

“…Although many anti-inflammatory medications have failed to reduce adverse cardiovascular outcomes in the CAD population, selected medications show promise among subgroups of patients without ACS or after the first week following an acute ischemic event. Future studies examining the proper timing and targetable anti-inflammatory pathways are warranted.…”
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Cellular Contractility Profiles of Human Diabetic Corneal Stromal Cells by Thi N. Lam, Sarah E. Nicholas, Alexander Choi, Jian-Xing Ma, Dimitrios Karamichos

“…These findings, and future studies, may contribute to better understanding of the pathobiology of diabetic keratopathy and ultimately the development of new therapeutic approaches.…”
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Optimising patient engagement for assessing total joint arthroplasty outcomes – a randomised controlled trial by Wyatt Tyndall, Nebojsa Kuljic, Michael Thatcher, Michaela Nickol, Johannes M. van der Merwe

“…Although the response improvements were limited and lacked statistical significance, the study highlights the importance of refining strategies to ensure reliable PROMS data, which is vital for understanding patient outcomes in TJA. Future studies might consider demographic factors and other outreach methods to enhance PROMs data collection.…”
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C3AR1 as a target for preeclampsia: from bioinformatics and network pharmacology to experimental validation by Yongfeng Hu, Shaoqiang Li, Yunhui Hong, Dongxian Peng

“…It is crucial for cellular functions and inflammation, with future studies aiming to leverage this for novel preeclampsia treatments. …”
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Referring psychiatric patients to occupational health services for earlier return to work – a qualitative implementation study of barriers and facilitators by Mikko Henriksson, Christina Tikka, Pirjo Juvonen-Posti, Marianna Virtanen, Tuula Oksanen

“…Helping health care workers contact possible cooperation partners and knowing how to address important individual, workplace-related and sociocultural factors such as stigma may strengthen collaboration between different sectors and stakeholders in mental health care. Future studies should focus on the multi-actor feasibility of the new collaborative models and include the patients’ perspective.…”
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