Cytotoxicity and Induction of Inflammation by Pepsin in Acid in Bronchial Epithelial Cells by Erik Bathoorn, Paul Daly, Birgit Gaiser, Karl Sternad, Craig Poland, William MacNee, Ellen M. Drost

“…Pepsin is cytotoxic to bronchial epithelial cells and induces inflammation in addition to acid alone, dependent on the level of acidity. Future studies should assess whether chronic aspiration causes airway remodelling in chronic inflammatory lung diseases.…”
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Identification and Pathogenicity of Causal Agents of Apple Canker Disease in Kazakhstan by Zhanar Tulegenova, Ulbike Amanbayeva, Aida M. Shalabayeva, Dina Yelyubayeva, Alikhan Zhaxylykov, Rabiga Uakhit, Ainura Smagulova, Vladimir Kiyan, Kazbek Dyussembayev, Gulzhamal Mukiyanova

“…Overall, this paper is a first report of the causal agents of apple canker disease in Kazakhstan and could be a trigger for conducting future studies to better understand the disease epidemiology, as well as build management strategies.…”
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Red wine maceration with grapevine-cane residues: Influence of format and toasting level by Verónica R. Olate-Olave, Liudis L. Pino-Ramos, Paula A. Peña-Martínez, Ricardo I. Castro, Marcelo Muñoz-Vera, Sergio Reyes-Manríquez, Gerard Casaubon, V. Felipe Laurie

“…Given that the cane format employed significantly influences the phenolic composition of the wines, future studies could explore the mechanisms behind these differing effects, as well as the sensorial implications of these changes.…”
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Residual limb neuropathic pain association with neuroma, prosthetic, function, and participation outcomes in individuals living with a transtibial amputation: an exploratory study by Camille Fournier-Farley, Mathieu Boudier-Revéret, Dany H. Gagnon

“…Conclusion: Though the results enrich currently available evidence on clinical variables potentially associated with the intensity of neuropathic pain in individuals living with a transtibial amputation, and on the limited value of US biomarkers studied to determine the association between neuroma(s) and pain intensity, future studies providing higher quality evidence remain needed. …”
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Preliminary Evidence for Feasibility, Use, and Acceptability of Individualized Texting for Adherence Building for Antiretroviral Adherence and Substance Use Assessment among HIV-In... by David J. Moore, Jessica L. Montoya, Kaitlin Blackstone, Alexandra Rooney, Ben Gouaux, Shereen Georges, Colin A. Depp, J. Hampton Atkinson, The TMARC Group

“…Qualitative feedback regarding the intervention was positive. Future studies will refine and improve iTAB for optimal acceptability and efficacy. …”
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A practical guide for nephrologist peer reviewers: understanding and appraising Mendelian randomization studies by Jianbo Qing, Yafeng Li, Karim M. Soliman, Wisit Cheungpasitporn

“…Additionally, limitations must be transparently addressed, with recommendations for replication in future studies, to strengthen findings. This article guides readers in understanding MR application in nephrology and identifying high-quality MR studies, helping peers avoid pitfalls while seizing new opportunities in advancing kidney disease research.…”
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Petroselinum crispum extract ameliorates scopolamine-induced cognitive dysfunction: role on apoptosis, inflammation and oxidative stress by Göksel Şener, Gözde Karakadıoglu, Dilek Ozbeyli, Seren Ede, Refiye Yanardag, Ozlem Sacan, Asli Aykac

“…However, since animal models do not completely mimic those of humans, based on the data obtained in this study, the importance of PC on human AD should be demonstrated in future studies.…”
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Dexmedetomidine Infusion Associated with Transient Adrenal Insufficiency in a Pediatric Patient: A Case Report by Elizabeth W. Tucker, David W. Cooke, Sapna R. Kudchadkar, Sybil Ann Klaus

“…While further studies will be needed to clarify the risk of adrenal suppression secondary to dexmedetomidine, this case suggests that caution should be taken when administering dexmedetomidine to pediatric patients and highlights the need for future studies to look at appropriate dosing and duration of dexmedetomidine infusions.…”
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Use of Telemedicine in Addiction Treatment: Current Practices and Organizational Implementation Characteristics by Todd Molfenter, Roger Brown, Andrew O’Neill, Ed Kopetsky, Alexander Toy

“…A Latent Class Analysis (LCA) of the organizations’ telemedicine use behavior identified three groupings: “Innovators” that were using a range of technologies (n=27, 7.4%); “Technology Traditionalists” that limited their use to telephone, video, and web portal technologies (n=101, 27.8%); and “Low Tech” that had low overall technology use (n=235, 64.7%). Future studies should build on how telemedicine could be applied in SUD settings, organizational behaviors towards its adoption, and telemedicine’s effect on treatment adherence and clinical outcomes.…”
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A Review of Sulfate Removal from Water Using Polymeric Membranes by Jamal Al Mehrate, Sadek Shaban, Amr Henni

“…This review found that studies in the literature dealt mainly with sulfate concentrations below 2000 mg/L, indicating a need to address higher concentrations in future studies.…”
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Investigation and Comparison of Some Laboratories in Terms of Occupational Health and Safety by ELMERI Observation Method by Orkun Dalyan, Mehmet Pişkin, Ömer Faruk Öztürk, Nuray Özkaya

“…It is suggested that the study will shed light on and form a source for future studies on laboratory safety and ELMERI observation method, especially in the laboratories where research was conducted.…”
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Optimizing Antipsychotic Therapy in Acute Alcoholic Hallucinosis through Pharmacogenetic Testing by Valentin Skryabin, Anton Masyakin, Sergei Pozdniakov, Igor Shatokhin, Svetlana Sokolova, Valentina Ivanchenko

“…This demonstrates that pharmacogenetic testing can optimize treatment safety without com- promising efficacy, suggesting that personalized therapy based on genetic profiles should be considered for alcohol-induced psychoses. Future studies with larger samples are recommended to validate these findings.…”
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Strategies Australian junior doctors use to maintain their mental, physical and social well-being: a qualitative study by Melanie Hobi, Sonya Yegorova-Lee, Christopher Chun-lin Chan, Hailin Zhao, Stephen Jiang, Dan Tran, Gayathri Nair, Erika Borkoles

“…Suggested interventions included increased control over rosters, subsidised access to facilities such as gyms and increased internship preparedness programmes organised by the medical schools.Conclusions The findings from this study may assist in developing more personalised and targeted methods to help junior doctors maintain their mental, physical and social well-being. Future studies may address the structural and systemic changes required to develop a workforce that fosters the well-being of junior doctors and reduces the institutional barriers to practising well-being strategies.…”
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Methimazole disrupted skeletal ossification and muscle fiber transition in Bufo gargarizans larvae by Fei Wei, Xueyi Wu, Hongyuan Wang, Yongpu Zhang, Lei Xie

“…In conclusion, these findings fill the data gap regarding MMI contamination in aquatic environments by revealing the negative effects of MMI on amphibian bone and muscle development. Future studies should address the toxicity of EDCs to wildlife and inform aquatic ecosystem conservation strategies.…”
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Effects of Arm Swing in Lower Limb Muscle Activation and Coordination During Treadmill Walking by Teresa Rodríguez-Millán, Clara B. Sanz-Morère, Agnese Cherubini, Rocío Urrutia, Filipe Oliveira Barroso, José L. Pons, Jesús Tornero

“…Our results suggest that arm swing influences LL muscle activity and coordination during walking. Future studies will aim at understanding the effects of arm swing in stroke rehabilitation, which could help design more effective gait rehabilitation protocols including arm swing.…”
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Laser-Induced Thermal Therapy in the Management of Low-Grade Gliomas: A Narrative Review by Ibrahim Omar hamed Dalabeh, Hossam Salameh, Yasmin Dahabreh, Abdallah Ali suleiman Al-Zayadneh, Mehreen Amir, Ayman Haitham Khaled, Malak A. Hassan, Azad Jehad Makableh, Mohammad Omar hamed Dalabeh

“…Conclusion: LITT represents a significant advancement in the treatment of LGGs, combining precision and minimal invasiveness. Future studies should focus on optimiz-ing protocols, integrating molecular and genetic in-sights, and assessing long-term outcomes to enhance therapeutic efficacy and patient quality of life. …”
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Deep Convolutional Neural Network Model for the Differential Diagnosis of Schizophrenia Using EEG Signals by Filiz Demirdöğen, Çağla Danacı, Seda Arslan Tuncer, Mustafa Akkuş, Sevler Yıldız

“…Conclusion: It is thought that the classification performance of the result obtained in the application is promising, and may be a guide for future studies.…”
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Neutrophil Extracellular Traps Contribute to the Disease Severity of Dengue Virus Infection by Cucunawangsih Cucunawangsih, Ratna Sari Wijaya, Nata Pratama Hardjo Lugito, Ivet Suriapranata

“…Conclusion: Our results suggest NETs have contributed to the disease severity of dengue infection. Future studies on the predictive value of NETs markers and the potential NETs as a targeted therapy in dengue disease should be priori­tized. …”
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The trypanosomatid (Kinetoplastida: Trypanosomatidae) parasites in bees: A review on their environmental circulation, impacts and implications by Rossella Tiritelli, Giovanni Cilia, Tamara Gómez-Moracho

“…The work highlights significant gaps in current knowledge and provides a valuable foundation for future studies. Understanding the pathogenicity and infection dynamics of trypanosomatids, along with the impact of environmental factors, is essential for developing effective conservation strategies that support pollinator health and overall ecosystem resilience.…”
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Modeling and simulation of magnet-coil arrays for vibrational energy harvesting in agricultural electric vehicles by Mbanwei Divine Kobbi, Njimboh Henry Alombah, Ngwa Martin Ngwabie

“…The energy harvested will be applied in future studies to extend the range of agricultural electric vehicles, reducing farmers’ income spent on fuel and maintenance.…”
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