Safety assessment of rosuvastatin-fenofibrate combination in the treatment of hyperlipidemia based on FDA’s adverse event reporting system database by Qun Li, Wenya Shan, Saiwei Wu

“…In this study, we analyzed the safety signals of rosuvastatin-fenofibrate combination by assessing the publicly available US Food and Drug Administration Adverse Event Reporting System (FAERS), so as to provide a reference for rational clinical use of rosuvastatin and fenofibrate, and reduce the occurrence of related AEs.MethodsReports to the FAERS from 1 January 2004 to 19 March 2020 were analyzed. …”
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A Systematic Literature Review and Indirect Treatment Comparison of Efficacy of Repository Corticotropin Injection versus Synthetic Adrenocorticotropic Hormone for Infantile Spasms by Michael S. Duchowny, Ishveen Chopra, John Niewoehner, George J. Wan, Beth Devine

“…RCI is a naturally-sourced complex mixture of purified ACTH analogs and other pituitary peptides approved by the United States Food and Drug Administration as a monotherapy for the treatment of infantile spasms. …”
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Six events that shaped antibody approvals in oncology by Suman Paul, Suman Paul, Shibin Zhou, Shibin Zhou

“…A little over twenty-five years ago, the European Medicines Agency (EMA) and the Food and Drug Administration (FDA) approved the chimeric antibody rituximab which fundamentally altered the landscape of anti-cancer drugs. …”
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Virtual Screening for Potential Inhibitors of NS3 Protein of Zika Virus by Maheswata Sahoo, Lingaraja Jena, Sangeeta Daf, Satish Kumar

“…Amodiaquine, prochlorperazine, quinacrine, and berberine are few promising drugs approved by Food and Drug Administration against dengue virus which also belong to Flaviviridae family. …”
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Facial Edema Evaluation Using Digital Image Processing by A. E. Villafuerte-Nuñez, A. C. Téllez-Anguiano, O. Hernández-Díaz, R. Rodríguez-Vera, J. A. Gutiérrez-Gnecchi, J. L. Salazar-Martínez

“…The results allow evaluating the measurement system before its use in a real test, using the pain model approved by the US Food and Drug Administration (FDA), which consists in extracting the third molar to generate the facial edema.…”
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Yindanxinnaotong, a Chinese compound medicine, synergistically attenuatesatherosclerosis progress by Long Cheng, Guo-feng Pan, Xiao-dong Zhang, Jian-lu Wang, Wan-dan Wang, Jian-yong Zhang, Hui Wang, Ri-xin Liang, Xiao-bo Sun

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A Novel Insight into Paraptosis-Related Classification and Signature in Lower-Grade Gliomas by Xi-Feng Qian, Jia-Hao Zhang, Yue-Xue Mai, Xin Yin, Yu-Bin Zheng, Zi-Yuan Yu, Guo-Dong Zhu, Xu-Guang Guo

“…We also confirmed the potential relationship of 10-PRG signatures and drug sensitivity of Food and Drug Administration–approved drugs. In summary, our findings provide a novel knowledge of paraptosis status and crucial direction to further explore the role of PRG signatures in LGG.…”
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Costs of Potential Medication Wastage Due to Switching Treatment Among People With Multiple Sclerosis by Darin T. Okuda, Achal Patel, Robert Schuldt, Ibraheem Abioye, Nicole G. Bonine

“…**Objectives:** To estimate the cost associated with potential medication wastage (PMW) in a subcohort of PwMS receiving oral or self-injectable US Food and Drug Administration–approved DMTs who switched DMTs in a calendar year in the United States. …”
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Exploring the Therapeutic Landscape: A Narrative Review on Topical and Oral Phosphodiesterase-4 Inhibitors in Dermatology by Elena Carmona-Rocha, Lluís Rusiñol, Lluís Puig

“…Apremilast was the first PDE4 inhibitor approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for psoriasis, psoriatic arthritis, and oral ulcers of Behcet’s disease. …”
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Cobalt titanate nanocatalyst for enhanced photodegradation of atrazine: kinetics, degradation efficiency, and mechanistic analysis by Jeremiah Suleiman Nuhu, Femi Emmanuel Awe, Rajni Garg, Rishav Garg, Nnabuk Okon Eddy, Hazratullah Paktin

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Mapping the global landscape of chikungunya rapid diagnostic tests: A scoping review. by José Moreira, Patrícia Brasil, Sabine Dittrich, André M Siqueira

“…National regulatory agencies (European Medicines Agency, US Food and Drug Administration, and the Brazilian National Health Surveillance Agency) were also searched for registered CHIKV RDTs.…”
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Tumor mutation burden for predicting immune checkpoint blockade response: the more, the better by Ming Zheng

“…Background Recently, the US Food and Drug Administration (FDA) has approved immune checkpoint blockade (ICB) for treating cancer patients with tumor mutation burden (TMB) >10 mutations/megabase (mut/Mb). …”
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Isolation, Characterization and Genetic Diversity of Aspergillus flavus in Animal Feed by Dina Al-Shinawy, Reda E.M. Moghaieb, Sara B. Awaly, Gihan El-Moghazy, Dalia S. Ahmed

“…The data showed that all samples except one (S1) contained total aflatoxin levels below 20 μg/ kg, considered safe for animal consumption according to the European Union (EU), United States Food and Drug Administration (US FDA), and World Health Organization (WHO) guidelines. …”
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Weizmannia coagulans: an ideal probiotic for gut health by Shiqi Zhang, Pinglan Li, Suwon Lee, Yu Wang, Chunming Tan, Nan Shang

“…W. coagulans has been generally recognized as safe (GRAS) by the US Food and Drug Administration (FDA), thus it is an ideal probiotic for improving gut health. …”
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Young adults’ cigarillo risk perceptions, attention to warning labels and perceptions of proposed pictorial warnings: a focus group study by Michelle Jeong, Olivia A Wackowski, Stefanie K Gratale, Andrew A Strasser, Cristine D Delnevo, Zeinab Safi, Anupreet Sidhu

“…Objective Although cigars pose similar health risks to cigarettes, they are not uniformly required to carry a warning label on their packaging in the USA. The US Food and Drug Administration’s 2016 deeming rule established a cigar warning requirement, but it was challenged in federal court for failing to document warning effects on prevention/cessation, thus necessitating an evidentiary base for such requirements. …”
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Expert consensus guidelines on management and best practices for tumor-infiltrating lymphocyte cell therapy by Sarah Nikiforow, John Haanen, Omid Hamid, Igor Puzanov, Rodabe Amaria, Amod Sarnaik, Marcus O Butler, Michael R Bishop, Allison Betof Warner, Adam J Schoenfeld, Krishna Komanduri

“…Based on the encouraging efficacy, tolerable safety profile, and advancements in a central manufacturing process, lifileucel is now the first US Food and Drug Administration (FDA)-approved TIL cell therapy product. …”
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Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice by Dai Fukumura, Rakesh K Jain, Jun Ren, Xinyue Dong, Zohreh Amoozgar, Somin Lee, Meenal Datta, Sylvie Roberge, Mark Duquette

“…In fact, the US FDA (Food and drug administration) has approved seven different combinations of anti-VEGF drugs and immune checkpoint blockers for liver, kidney, lung and endometrial cancers in the past 3 years. …”
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Health-related quality of life outcomes reporting associated with FDA approvals in haematology and oncology by Bishal Gyawali, Pallawi Torka, Kristopher Attwood, Medhavi Gupta, Othman Salim Akhtar, Bhavyaa Bahl, Angel Mier-Hicks, Kayla Catalfamo

“…This study aimed to examine the HRQoL reporting in cancer drug trials leading to Food and Drug Administration (FDA) approvals.Methods and analysis This retrospective cohort study analysed HRQoL data for trials leading to FDA approvals between July 2015 and May 2020. …”
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Quantification of Escherichia coli Transfer from Plastic Mulch to Field-grown Tomatoes and Bell Peppers by Autumn R. Burnett, Faith Critzer, Timothy Coolong

“…In the United States, the Food and Drug Administration (USFDA) prohibits the distribution of fruit that is dropped from the plant and contacts the ground during harvest. …”
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Lactoferrin: a secret weapon in the war against pathogenic bacteria by Lucero Ruiz-Mazón, Gerardo Ramírez-Rico, Mireya de la Garza

“…Bovine Lf (bLf) has been approved by the US Food and Drug Administration (FDA), and the European Food Safety Authority for its use as a dietary supplement in food products. …”
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