FDA-approved kinase inhibitors: a promising therapeutic avenue for traumatic brain injury by Dezhu Gao, Yu Shi, Zhiliang Wang, Weiming Liu

“…Nowadays, kinase inhibitors approved by the Food and Drug Administration (FDA) mainly for cancer treatment have shown potential effects in TBI. …”
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Pimobendan oral solution is bioequivalent to pimobendan chewable tablets in beagle dogs by Olaf Kuhlmann, Michael Markert

“…Conclusions and Clinical Importance The novel oral solution of pimobendan was found to be bioequivalent, both applying the Food and Drug Administration (FDA) supported RSABE method and based on pharmacodynamic data. …”
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Safety and effectiveness of an herbal decoction (modified Saengmaeksan) in hypertensive patients: Protocol for a real-world prospective observational study. by Nahyun Cho, Hobin Moon, Kyung-Min Shin, Byoung-Kab Kang, Jungtae Leem, Changsop Yang

“…The study's goal is to support the approval of modified Saengmaeksan as a hypertension treatment by the South Korean Food and Drug Administration and to promote the industrialization of traditional herbal medicine in managing hypertension. …”
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Second-generation anti-amyloid monoclonal antibodies for Alzheimer’s disease: current landscape and future perspectives by Byeong-Hyeon Kim, Sujin Kim, Yunkwon Nam, Yong Ho Park, Seong Min Shin, Minho Moon

“…Specifically, based on their efficacy in removing Aβ plaques from the brains of patients with AD, the U.S. Food and Drug Administration has approved three anti-amyloid MABs, aducanumab (Aduhelm®), lecanemab (Leqembi®), and donanemab (Kisunla™). …”
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Food recalls: An unnecessary and preventable factor in food waste by Rubén Morawicki

“…Depart­ment of Agriculture (USDA) and the U.S. Food and Drug Administration (FDA) into three classes based on the severity of health risks, with Class I being the most severe; a Class I recall is for defec­tive products that can cause severe health effects or death (FDA, 2024, p. 7-1; UDSA Food Safety and Inspection Service [USDA FSIS], 2024-b). …”
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Investigating the Safety of Fampridine in Patients with Different Stages of Multiple Sclerosis by Saeed Vaheb, Mahour Farzan, Alireza Afshari-Safavi, Narges Ebrahimi, Vahid Shaygannejad, Omid Mirmosayyeb

“…Background: Fampridine is the only drug approved by the US Food and Drug Administration (FDA) for people with multiple sclerosis (MS) to improve their movement and has exhibited a clinically significant improvement in gait function in a subset of MS patients with Expanded Disability Status Scale (ESDSS) from 4 to 7. …”
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Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential by Jingyi Yuan, Zhenmin Li, Yongjiang Yu, Xiuge Wang, Yunyun Zhao

“…However, these treatments may often lead to adverse effects, and most medications prescribed for PCOS are used off-label and have not secured approval from the U.S. Food and Drug Administration specifically for this condition. …”
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QSPR Analysis of Some Alzheimer’s Compounds via Topological Indices and Regression Models by Muhammad Shoaib Sardar, Khalil Hadi Hakami

“…Alzheimer’s disease (AD) is of particular importance among pathologies, and despite approved drugs for its treatment, there is no effective pharmacological therapy to stop, halt, or repair neurodegeneration. The U.S. Food and Drug Administration (FDA) has approved certain medications to treat AD, including galantamine, donepezil, rivastigmine, memantine, tacrine, suvorexant, brexpiprazole, butein, and Licochalcone A. …”
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Cancer vaccines: platforms and current progress by Wanting Lei, Kexun Zhou, Ye Lei, Qiu Li, Hong Zhu

“…Despite the US Food and Drug Administration approval for several vaccines, the full therapeutic potential remains unrealized due to challenges such as antigen selection, tumor-mediated immunosuppression, and optimization of delivery systems. …”
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Targeting BCMA in multiple myeloma: designs, challenges, and future directions by Yi Hu, Yuetao Xie, Xiaodong Wang, Lufeng Yang, He Geng, Zugang Yi, Yao Zhang, Lin Ma, Fang Chen

“…Various CAR designs, utilizing different BCMA recognition domains, have yielded promising clinical results, leading to the approval of two BCMA-targeting CAR T cell therapies by the US Food and Drug Administration (FDA) for the treatment of MM. This review uniquely examines the BCMA CAR T cell landscape, emphasizing the design of recognition domains, clinical efficacy, and patient outcomes. …”
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Sources of Dietary Fiber and the Association of Fiber Intake with Childhood Obesity Risk (in 2–18 Year Olds) and Diabetes Risk of Adolescents 12–18 Year Olds: NHANES 2003–2006... by Mary Brauchla, WenYen Juan, Jon Story, Sibylle Kranz

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Identification of Potential Herbal Inhibitor of Acetylcholinesterase Associated Alzheimer’s Disorders Using Molecular Docking and Molecular Dynamics Simulation by Chandrabhan Seniya, Ghulam Jilani Khan, Kuldeep Uchadia

“…Cholinesterase inhibitors (ChE-Is) are the standard for the therapy of AD associated disorders and are the only class of approved drugs by the Food and Drug Administration (FDA). Additionally, acetylcholinesterase (AChE) is the target for many Alzheimer’s dementia drugs which block the function of AChE but have some side effects. …”
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Clinical Use of Dostarlimab in Advanced Stage and Recurrent Endometrial Cancer: Patient Selection and Perspectives by Bujnak AC, File B, Tewari KS

“…On August 1st, 2024, the United States Food and Drug Administration expanded the indication of the immunologic anti-PD-1 checkpoint inhibitor, dostarlimab, and chemotherapy in endometrial cancer. …”
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Efficacy and tolerance of second-generation antipsychotics in anorexia nervosa: A systematic scoping review. by Solène Thorey, Corinne Blanchet, Sélim Benjamin Guessoum, Marie Rose Moro, Maude Ludot, Emilie Carretier

“…However, few clinical trials have been conducted so far and no pharmacological treatment has yet been approved by the Food and Drug Administration. The aim of this paper is to conduct a systematic scoping review exploring the effectiveness and safety of atypical antipsychotics in anorexia nervosa (AN).…”
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Rapid Colorimetric Detection of Hg (II) Based on Hg (II)-Induced Suppressed Enzyme-Like Reduction of 4-Nitrophenol by Au@ZnO/Fe3O4 in a Cosmetic Skin Product by Oratile Semong, Bareki Shima Batlokwa

“…The material exhibited excellent analytical performance as marked by the very low limit of detection (LOD) of 2.34 nM, which was well below acceptable levels of 4.99 μM for mercury in cosmetics as set by the US Food and Drug Administration (FDA), and within the linear dynamic ranges of 0–10 nM. …”
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Fluorescent Nanoparticle Imaging Allows Noninvasive Evaluation of Immune Cell Modulation in Esophageal Dysplasia by Peiman Habibollahi, Todd Waldron, Pedram Heidari, Hoon Sung Cho, David Alcantara, Lee Josephson, Timothy C. Wang, Anil K. Rustgi, Umar Mahmood

“…The agent we developed for imaging is synthesized from Feraheme (ferumoxytol), a Food and Drug Administration-approved monocrystaline dextran-coated iron oxide nanoparticle, which we conjugated to a near-infrared fluorochrome, CyAL5.5. …”
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The Role of Red Blood Cell Distribution Width in the Severity and Prognosis of Community-Acquired Pneumonia by Qiang Ren, Hebing Liu, Ying Wang, Deyu Dai, Zhennan Tian, Guiwei Jiao, Xiaomin Liu

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Medical imaging-based companion diagnostics for solid tumors by Rui Yin, Qingpeng Zhang, Shiyi Liao, Chang Lu, Cheng Zhang, Qingyun Cai, Guosheng Song

“…However, most current US Food and Drug Administration (FDA)-approved CDx tests have difficulty dynamically reflecting variations in biomarkers in the solid tumor microenvironment because they are used in vitro and ex vivo. …”
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Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review by Giannopoulos A, Singh J, Deligiannidis KM

“…Zuranolone is the first US Food and Drug Administration approved oral antidepressant for adult females with PPD. …”
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Factors Affecting Compliance of Infection Control Measures among Dental Radiographers by Maram Alakhras, Dana S. Al-Mousa, Arwa Mahasneh, Amani G. AlSa’di

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