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The association of gut microbiota, immunocyte dynamics, and protein–protein ratios with tuberculosis susceptibility: a Mendelian randomization analysis
Published 2025-01-01“…By analyzing the GWAS data of individuals with European ancestry (the FinnGen dataset included 409,568 controls and 2613 cases), using the two-sample MR method, we focused on evaluating the impact of immunocyte-mediated gut microbiota on tuberculosis and the associations between 2821 plasma protein-to-protein ratios and tuberculosis. …”
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Causal associations between circulating protein ratios and drug resistance in papillary thyroid cancer: a Mendelian randomization study
Published 2025-01-01“…Methods Genetic data for 2821 CPLRs were obtained from the GWAS and FinnGen databases. Mendelian randomization (MR) analysis, using inverse variance weighting (IVW) as the primary method, was conducted to explore causality. …”
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Frihet og vennskap. Om ungdom og rusopplevelser
Published 2025-01-01“…De fleste norske ungdommer eksperimenterer med alkohol i løpet av tenårene, og det finnes en rekke forskningsbidrag som undersøker sårbarhetsfaktorer for tidlig alkoholdebut eller belyser de negative konsekvensene av ungdoms alkoholbruk. …”
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A cross-tissue transcriptome-wide association study identified susceptibility genes for age-related macular degeneration
Published 2025-02-01“…A transcriptome-wide association study (TWAS) was conducted by integrating eQTL data from 49 tissues of the Genotype-Tissue Expression Project (GTEx) v8 and AMD data from FinnGen R10. The Unified Test for Molecular Signatures (UTMOST) and Functional Summary-based Imputation (FUSION) were used to evaluate gene associations with AMD across tissues and within individual tissues, respectively. …”
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The causal association of cheese intake with type 2 diabetes mellitus: results from a two-sample Mendelian randomization study
Published 2024-05-01“…Material and methods Summary cheese intake statistics were obtained from UK Biobank and publicly available genome-wide association studies (GWAS) for type 2 diabetes from IEU OpenGWAS, FinnGen Biobank, EBI GWAS, and Biobank Japan. The primary method was pooled meta-analysis with the inverse variance weighting method. …”
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Mendelian randomization analysis reveals genetic evidence for a causal link between inflammatory bowel disease and uterine cervical neoplasms
Published 2025-01-01“…We aimed to evaluate the causal relationship between IBD and uterine cervical neoplasm using a bidirectional Mendelian randomization analysis.MethodsWe derived instrumental variables for IBD, including Crohn’s disease and ulcerative colitis, from the IEU Open genome-wide association study (GWAS) database, and for the histological subtypes of uterine cervical neoplasm from the FinnGen repository’s GWAS data. The collected GWAS data predominantly represent individuals of European ancestry. …”
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Makro-deliberasjon i lokalpolitiske debatter<subtitle>Macro-deliberation in Local Political Debates</subtitle>
Published 2025-01-01“…Denne artikkelen setter søkelys på deliberativt demokrati i samfunnsdebatten gjennom å belyse ulike arenaer hvor et lokalt vekst/vern-problem diskuteres i forbindelse med utbyggingen av et større reiselivsanlegg, Arctic Center i Tromsø. Formålet er å finne ut i hvilken grad ulike arenaer ivaretar sentrale deliberative elementer, hvordan arenaene virker i forhold til hverandre, og hvordan de kan påvirke meningsutveksling og meningsdannelse. …”
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Causal relationship between circulating vitamin C and 25-hydroxyvitamin D concentrations and common mental disorders - a Mendelian randomization study
Published 2024-07-01“…The data used for the MR analysis were derived from the summary genome-wide association studies (GWAS) database for VC and 25(OH)D and from the FinnGen consortium for fourteen mental disorders. …”
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A multi-trait approach identified 7 novel genes for back pain
Published 2025-02-01“…Finally, we replicated significantly associated genes using the FinnGen database. Results:. We identified 32 genes associated with BP and replicated 16 of them. …”
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Proteome-wide mendelian randomization identifies causal plasma proteins in interstitial lung disease
Published 2025-01-01“…We utilized the most recent large-scale plasma protein quantitative trait loci (pQTL) data detected from the antibody-based method and ILD and its subtypes’ GWAS data from the updated FinnGen database for Mendelian randomization analysis. …”
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Bidirectional Mendelian Randomization Analysis to Study the Relationship Between Human Skin Microbiota and Radiation-Induced Skin Toxicity
Published 2025-01-01“…Summary datasets of human skin microbiota were extracted from the GWAS catalog database, and summary datasets of radiation-induced skin toxicity from the FinnGen biobank. Mendelian Randomization (MR) analysis was leveraged to sort out the causal link between skin microbiota and radiation-induced skin toxicity. …”
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Second harmonic Bessel-Gauss beam shaping with elliptic axicon aberrations
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Sirkusdirektør Arnardos manesjespråk
Published 2024-12-01“…Dette knytter vi til en diskusjon om hvor vi kan finne røttene til dette språket.…”
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State of the art for walking as a transport mode within 15-minute cities
Published 2025-12-01Get full text
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