Immunological Regulation of Fibrosis During Heart Failure: It Takes Two to Tango by Vinay Kumar, Shyam S. Bansal

“…Immuno-fibrotic networks and their protein mediators, such as cytokines and chemokines, have increasingly been appreciated for their critical role in cardiac healing and fibrosis during cardiomyopathy. Immune activation, trafficking, and extravasation are tightly regulated to ensure a targeted and effective response against non-self antigens/pathogens while preserving tolerance towards self-antigens and coordinate fibrotic responses for efficient scar formation, a distinction that is severely compromised during chronic diseases. …”
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Modulation of Biomaterial‐Associated Fibrosis by Means of Combined Physicochemical Material Properties by Lisa E. Tromp, Torben A.B. van derBoon, Roderick H.J. deHilster, Ruud Bank, Patrick van Rijn

Subjects: “…biomaterial‐associated fibrosis…”
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Model of Liver Fibrosis Induction by Thioacetamide in Rats for Regenerative Therapy Studies by Nathaly Enciso, José Amiel, Fredy Fabián-Domínguez, Jhon Pando, Nancy Rojas, Carlos Cisneros-Huamaní, Ernesto Nava, Javier Enciso

“…Hepatic fibrosis is caused by chronic injury due to toxic, infectious, or metabolic causes, and it may progress to cirrhosis and hepatocellular carcinoma. …”
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A Chinese Traditional Therapy for Bleomycin-Induced Pulmonary Fibrosis in Mice by Lifang Sun, Minjie Mao, Zhisheng Yan, Cuiyun Zuo, Xiaojie Zhang

“…Pulmonary fibrosis is a chronic and fatal disease of lung tissue with high incidence and mortality in the world. …”
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Physiological Stimulation of the Synthesis of Preelastic Fibers in the Dermis of a Patient with Fibrosis by Jose Maria Pereira de Godoy, Lívia Maria Pereira de Godoy, Maria de Fatima Guerreiro Godoy, Dalisio de Santi Neto

“…The aim of the present study was to report the physiological stimulation of the synthesis of preelastic fibers in the dermis of a patient with fibrosis. Design. A clinical study was conducted involving the analysis of histological changes in preelastic fibers following treatment for stage II primary lymphedema for the clinical reversal of lymphedema and fibrosis. …”
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CT-sensitized nanoprobe for effective early diagnosis and treatment of pulmonary fibrosis by Jiwei Hou, Qijian Ji, Tianyu Tang, Yonger Xue, Lin Gao, Li Dai, Jinbing Xie

Subjects: “…Pulmonary fibrosis…”
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Proteomics profiling of inflammatory responses to elexacaftor/tezacaftor/ivacaftor in cystic fibrosis by Hazel Ozuna, Hazel Ozuna, Dinesh Bojja, Santiago Partida-Sanchez, Luanne Hall-Stoodley, Amal Amer, Rodney D. Britt, Rodney D. Britt, Shahid Sheikh, David A. Frank, Weiyuan Wang, Bum-Yong Kang, Bum-Yong Kang, Irina Miralda, Irina Miralda, Samantha L. Durfey, Samantha L. Durfey, Benjamin T. Kopp, Benjamin T. Kopp

Subjects: “…cystic fibrosis…”
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Novel transcripts of EMT driving the malignant transformation of oral submucous fibrosis by Smitha Sammith Shetty, Kanaka Sai Ram Padam, Mohit Sharma, Adarsh Kudva, Pratik Patel, Raghu Radhakrishnan

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Myofibroblast-derived exosomes enhance macrophages to myofibroblasts transition and kidney fibrosis by Wenqiang Yu, Jinfang Song, Shuangquan Chen, Jiayi Nie, Chujun Zhou, Jiamin Huang, Hua Liang

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Progress and prospects of elastography techniques in the evaluation of fibrosis in chronic liver disease by Yang Wang, Xiaohuan Yang, Sisi Wang

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Imaging Diagnosis of Interstitial Pneumonia with Emphysema (Combined Pulmonary Fibrosis and Emphysema) by Fumikazu Sakai, Junya Tominaga, Akiko Kaga, Yutaka Usui, Minoru Kanazawa, Takashi Ogura, Noriyo Yanagawa, Tamiko Takemura

“…Based on clinical and radiological findings, Cottin defined combined pulmonary fibrosis and emphysema (CPFE) as pulmonary emphysema in the upper lungs and interstitial pneumonia in the lower lungs with various radiological patterns. …”
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Patient Perspectives on the Use of Digital Technology to Help Manage Cystic Fibrosis by Alexandre H. Watanabe, Connor Willis, Russell Ragsdale, Joseph Biskupiak, Karlene Moore, Diana Brixner, David Young

“…Digital health technologies (DHTs) have shown potential to improve health outcomes through improved medication adherence in different disease states. Cystic fibrosis (CF) requires care coordination across pharmacies, patients, and providers. …”
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Anesthetic Management and Considerations for Cesarean Delivery in a Patient With Cystic Fibrosis by Richard Pham, Chris Mehdizadeh, Christopher Baker, Leonard J. Soloniuk, Ioana Pasca, Ashish Sinha

“…Recent advancements in therapeutics and risk reduction in the management of cystic fibrosis have increased the life expectancy of cystic fibrosis patients to the fifth decade of life. …”
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Mixed Comparative Evaluation of a Training Program Dedicated to Cystic Fibrosis Reference Centers: Protocol for the Pilot Implementation of Shared Decision-Making in the Treatment of Diabetes in Adult Patients With Cystic Fibrosis by Nora Moumjid, Constance Gotte, Sophie Hommey, Stéphanie Poupon Bourdy, Julie Haesebaert, Isabelle Durieu, Quitterie Reynaud

“…Two treatment options are possible: start insulin as soon as cystic fibrosis diagnosis is made with the additional constraints of cystic fibrosis or wait while monitoring the patient’s clinical condition and start insulin when diabetes symptoms develop and therefore later. …”
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Identification and Analysis of Key Immune- and Inflammation-Related Genes in Idiopathic Pulmonary Fibrosis by Tan Y, Qian B, Ma Q, Xiang K, Wang S

Subjects: “…idiopathic pulmonary fibrosis…”
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Gene therapy by hepatocyte growth factor results in regression of experimental liver fibrosis by N. A. Dzhoyashvili, N. I. Kalinina, I. B. Beloglazova, Z. I. Tsokolayeva, P. I. Makarevich, Yu. L. Perov, Ye. V. Parfenova, V. A. Tkachuk

Subjects: “…liver fibrosis…”
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Role of Epigenetic Histone Modifications in Diabetic Kidney Disease Involving Renal Fibrosis by Jing Sun, Yangwei Wang, Wenpeng Cui, Yan Lou, Guangdong Sun, Dongmei Zhang, Lining Miao

“…Histone modifications are also implicated in renal fibrosis through its ability to regulate the EMT process triggered by TGF-β signaling. …”
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Rapid Quantification of Myocardial Fibrosis: A New Macro-Based Automated Analysis by Awal M. Hadi, Koen T. B. Mouchaers, Ingrid Schalij, Katrien Grunberg, Gerrit A. Meijer, Anton Vonk-Noordegraaf, Willem J. van der Laarse, Jeroen A. M. Beliën

“…Background: Fibrosis is associated with various cardiac pathologies and dysfunction. …”
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Radiation Induces Pulmonary Fibrosis by Promoting the Fibrogenic Differentiation of Alveolar Stem Cells by Lu-Kai Wang, Tsai-Jung Wu, Ji-Hong Hong, Fang-Hsin Chen, John Yu, Chun-Chieh Wang

“…Irradiated alveolar epithelial cells promote radiation-related pneumonitis and fibrosis. However, the role of lung stem cells (LSCs) in the development of radiation-induced lung injury is still unclear. …”
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Isoniazid and Rifampicin Produce Hepatic Fibrosis through an Oxidative Stress-Dependent Mechanism by Ayan Biswas, Suman Santra, Debasree Bishnu, Gopal Krishna Dhali, Abhijit Chowdhury, Amal Santra

“…We sought evidence of the production of hepatic fibrosis on long-term INH-RMP treatment through experiments in BALB/c mice exposed to INH-RMP. …”
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