Oncological outcomes in non-seminomatous testicular tumors and residual mass after cisplatin-based chemotherapy by María A. Ocampo-Gómez, María C. Moreno-Matson, David Ruiz-Londoño, Marino Cabrera, Rodolfo Varela

“…Patients with viable tumors after RPLND had shorter OS compared to patients with teratoma and fibrosis. Conclusions: RPLND continues to be the treatment of choice to patients with RM after CT and NSM. …”
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Extensive Sclerosing Mesenteritis of the Rectosigmoid Colon Associated with Erosive Colitis by C. Nobili, L. Degrate, R. Caprotti, C. Franciosi, B. E. Leone, F. Romano, M. Dinelli, Fr. Uggeri

“…Histological examination showed extended fibrosis, inflammatory cells infiltration, lipophages, and granulomas within the mesenteric adipose tissue associated with erosive colitis. …”
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A Unique Case of Incomplete Bifid Ureter and Associated Arterial Variations by Shivika Ahuja, Hannah Sullivan, Mark Noller, Yun Tan, Daniel Daly

“…Compression of renal and ovarian vasculature can result in altered blood flow to the kidney and ovary, potentially causing fibrosis, atrophy, or organ failure. Current imaging techniques alone are insufficient for correct diagnostics of such complications, and they must be supplemented with a thorough understanding of the respective anatomical variations.…”
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Unusual Cutaneous Manifestations in a Patient with a History of Hepatitis B: A Case of Scleromyxedema and Literature Review by Gao A, Tian X, Lang D, Chen Y

“…Histopathological examination revealed mucin deposition, fibroblast proliferation, and fibrosis, supporting the diagnosis. Serum protein electrophoresis identified IgG-λ type paraproteinemia. …”
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The role of non-alcoholic fatty liver disease in the formation of atherosclerotic vascular lesions in patients with abdominal obesity by N. L. Denisov, V. B. Grinevich, Ye. V. Chernetsova, Yu. A. Kravchuk, K. V. Ivashkin

“…Severity of pathological changes in the liver tissue (fibrosis and steatosis) was assessed by noninvasive Steatoskrin diagnostic method (Biopredictive laboratory, France). …”
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A Case Report Demonstrating How the Clinical Presentation of the Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma Can Mimic Benign Riedel’s Thyroiditis by Jennifer Walsh, Tomas P. Griffin, Carmel B. Ryan, James Fitzgibbon, Patrick Sheahan, Matthew S. Murphy

“…This showed dense sclerotic fibrosis punctuated by nodular mononuclear inflammatory cells, which obscured follicular epithelial cells consistent with a fibrosing thyroiditis (Riedel’s thyroiditis). …”
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The Relationship among Physical Activity, Intestinal Flora, and Cardiovascular Disease by Qiuyu Yan, Wenhui Zhai, Chenghao Yang, Zihao Li, Longfei Mao, Mingyi Zhao, Xiushan Wu

“…Cardiovascular diseases (CVDs), which are associated with high morbidity and mortality worldwide, include atherosclerosis (AS), hypertension, heart failure (HF), atrial fibrillation, and myocardial fibrosis. CVDs are influenced by the diversity, distribution, and metabolites of intestinal microflora, and their risk can be reduced through physical activity (PA) such as regular exercise. …”
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Hypolipidemic Effect of Chloroform Extract of Lagenaria siceraria: Potential Inhibitory Activity of Phytochemicals Targeting the HMG-CoA Reductase Revealed by Molecular Docking and... by Qudsia Kanwal, Mahmood Ahmed, Atiq Ur-Rehman, Aneela Anwar, Samiah Shahid, Atif Shahzad, Attaullah Shah Bukhari, Muhammad Ahmad, Numan Yousaf, Muhammad Muddassar

“…On the 8th day, no inflammation of the liver, myocardial necrosis, fibrosis, or atypia was seen. Furthermore, binding affinity and plausible binding mode of stigmastan-3-ol with HMG-CoA reductase were predicted by molecular docking studies which showed the same interaction patterns as atorvastatin. …”
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The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background by Jinsheng Yu, Sharon Marsh, Junbo Hu, Wenke Feng, Chaodong Wu

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world, and it comprises a spectrum of hepatic abnormalities from simple hepatic steatosis to steatohepatitis, fibrosis, cirrhosis, and liver cancer. While the pathogenesis of NAFLD remains incompletely understood, a multihit model has been proposed that accommodates causal factors from a variety of sources, including intestinal and adipose proinflammatory stimuli acting on the liver simultaneously. …”
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HВcorAg expression in HВeАg-negative hepatitis: correlation to clinical and histological activity and HВsAg-status by O. P. Dudanova, I. A. Pravdolyubova

“…Routine laboratory tests, Knodell histological activity index and modified index, Metavir fibrosis score were assessed.Results. In 25 patients (78,1%) cytoplasmic and nuclear HBcorAg expression and in 7 (21,9%) – only cytoplasmic HBcorAg expression was revealed. …”
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Hemosiderin-Laden Macrophages in Bronchoalveolar Lavage: Predictive Role for Acute Exacerbation of Idiopathic Interstitial Pneumonias by Toru Arai, Tomoko Kagawa, Yumiko Sasaki, Reiko Sugawara, Chikatoshi Sugimoto, Kazunobu Tachibana, Yoshiki Fujita, Seiji Hayashi, Yoshikazu Inoue

“…Hemosiderin-laden macrophages (HLMs) have been identified in the bronchoalveolar lavage fluid (BALF) of patients with idiopathic pulmonary fibrosis (IPF). This retrospective study examined the ability of HLMs in BALF to predict the acute exacerbation (AE) of chronic idiopathic interstitial pneumonias (IIPs). …”
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Autoantibody with Cross-Reactivity between Insulin and Ductal Cells May Cause Diabetic Mastopathy: A Case Study by Katsutoshi Miura, Chikako Teruya, Nasu Hatsuko, Hiroyuki Ogura

“…Lymphocytic mastopathy or diabetic mastopathy is a benign breast disease characterized by dense fibrosis, lobular atrophy, and aggregates of lymphocytes in a periductal and perilobular distribution. …”
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Circulating Galectin-3 and Atrial Fibrillation Recurrence after Catheter Ablation: A Meta-Analysis by Guangping Zhang, Yongquan Wu

“…Galectin-3 (Gal-3) is involved in fibrosis and heart failure. However, epidemiological studies evaluating the association between Gal-3 and atrial fibrillation (AF) recurrence after catheter ablation showed inconsistent results. …”
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Magnetic Resonance Imaging Evaluation in Patients with Linear Morphea Treated with Methotrexate and High-Dose Corticosteroid by Mohammad Shahidi-Dadras, Fahimeh Abdollahimajd, Razieh Jahangard, Ali Javinani, Amir Ashraf-Ganjouei, Parviz Toossi

“…Morphea is an inflammatory disease of the connective tissue that may lead to thickening and hardening of the skin due to fibrosis. The aim of this study was to document magnetic resonance imaging (MRI) changes in patients with linear morphea who were treated with methotrexate (MTX) and high-dose corticosteroid. …”
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The deleterious effects of CDK4/6 inhibition on renal recovery post-acute kidney injury by Shanshan Zhou, Rouzhang Peng, Yanting Shen, Liuwei Huang, Suying Han, Jun Wang, Jie Guo

“…We found that Palb could cause renal senescence and renal fibrosis. Furthermore, dasatinib (D) plus quercetin (Q) were used to eliminate senescent cells in ischemic AKI murine model and Palb was administered post the treatment of D + Q. …”
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Sestrin2 Signaling Pathway Regulates Podocyte Biology and Protects against Diabetic Nephropathy by Moein Ala

“…Consistently, overexpression of Sestrin2 ameliorated podocyte injury, mesangial proliferation, proteinuria, and renal fibrosis in animal models of diabetic nephropathy. …”
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Autologous Fat Grafting in the Treatment of Facial Scleroderma by Mehdi Gheisari, Arman Ahmadzadeh, Nilofar Nobari, Behzad Iranmanesh, Nikoo Mozafari

“…Systemic sclerosis (SSc) is a rare systemic autoimmune disease, characterized by progressive cutaneous and internal organ fibrosis. Orofacial manifestations of systemic sclerosis are extremely disabling and treatment options are limited. …”
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Glycogen Storage Disease Type IX due to a Novel Mutation in PHKA2 Gene by Hamza Hassan Khan, Lauren Parr, Allison Jay, Saleem Raza, Hernando Lyons, Sanjay Kumar

“…Liver and muscle biopsies were obtained: the liver biopsy revealed distended hepatocytes with excessive glycogen accumulation and fine septate fibrosis. Biopsy of the right vastus lateralis muscle showed focal swollen glycogen containing mitochondria. …”
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A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements by Kazuhiko Higashioka, Kenji Yoshida, Kensuke Oryoji, Kazuo Kamada, Shinichi Mizuki, Hiroshi Tsukamoto, Eisuke Yokota, Koichi Akashi

“…This case showed many clinical findings, such as bilateral swelling of salivary and lacrimal glands, autoimmune pancreatitis, interstitial nephritis, retroperitoneal fibrosis, periaortitis, systemic swelling of lymph nodes, pulmonary lesions, splenomegaly, and jejunal lesions. …”
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Etoricoxib–NLC Mitigates Radiation-Induced Ovarian Damage in Rats: Insights into Pro-Inflammatory Cytokines, Antioxidant Activity, and Hormonal Responses by Sahar Khateeb

“…These therapeutic effects were achieved through the modulation of oxidative stress, inflammation, augmentation of antioxidant defenses (including <i>Nrf2</i> activation), support for cell survival pathways (via PI3K/Akt signaling), regulation of MAPK, mitigation of fibrosis (<i>TGF-β</i>), and preservation of ovarian reserve (as evidenced by AMH, FSH/LH, and estrogen levels). …”
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