Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury by Honglei Guo, Hongmei Li, Lilu Ling, Yong Gu, Wei Ding

“…We demonstrate that Aldo leads to impaired renal function and inhibition of ER stress via TUDCA attenuates renal fibrosis. This was indicated by decreased collagen I, collagen IV, fibronectin, and TGF-β expression, as well as the downregulation of the expression of Nlrp3 inflammasome markers, Nlrp3, ASC, IL-1β, and IL-18. …”
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Western Diet Decreases Hepatic Drug Metabolism in Male LDLr−/−ApoB100/100 Mice by Markus Koponen, Jaana Rysä, Anna-Kaisa Ruotsalainen, Olli Kärkkäinen, Risto O. Juvonen

“…Hepatic steatosis, lobular inflammation, and early fibrosis were observed in WD fed mice, but not in chow diet control mice. …”
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The Skin as a Window to Diabetes Mellitus: Manifestations, Complications and Clinical Insights by Aleksandra Kutaj, Zuzanna Adamowicz

“…These pathological changes contribute to various dermatological symptoms, including xerosis, pruritus, erythema, and fibrosis. Skin changes, such as diabetic dermopathy, necrobiosis lipoidica, and recurrent fungal infections, are not only indicators of DM but also reflect glycemic control and disease severity. …”
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In Silico, In Vitro, and In Vivo Wound Healing Activity of Astragalus microcephalus Willd. by Fatemeh Akbari, Mohammad Azadbakht, Ali Bagheri, Lale Vahedi

“…Histopathological results confirmed these findings; inflammation factors decreased, and fibroblast proliferation, fibrosis, and epithelization increased, especially in the extract group. …”
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Nanomaterials: Promising Tools for the Diagnosis and Treatment of Myocardial Infarction by Ge Y, Wu L, Mei S, Wu J

“…We systematically review the applications of nanomaterials in MI diagnosis, including the detection of biomarkers and imaging techniques, as well as in MI treatment, encompassing anti-inflammatory effects, antioxidant stress, inhibition of fibrosis, promotion of angiogenesis, and cardiac conduction repair. …”
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Safety Profile of Liver FibroScan in Patients with Cardiac Pacemakers or Implantable Cardioverter-Defibrillators by Yin Chan, Stephanie Pranke, Farid Rashidi, Shravan Nosib, Lawrence Worobetz

“…The FibroScan (Echosens, France), a widely available, noninvasive device, is able to detect liver fibrosis and steatosis within this patient population. …”
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Diabetic Muscle Infarction: A Rare Cause of Acute Limb Pain in Dialysis Patients by G. De Vlieger, B. Bammens, F. Claus, R. Vos, K. Claes

“…In the current paper, we present two diabetic patients with cystic fibrosis, who are treated with automated peritoneal dialysis and suffered from episodic lower limb infarction. …”
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Mitochondrial transplantation for cardioprotection and induction of angiogenesis in ischemic heart disease by Parisa Hassanpour, Fatemeh Sadeghsoltani, Solmaz Saghebasl, Safieh Boroumand, Parisa Khanicheragh, Seyed Hossein Ahmadi Tafti, Reza Rahbarghazi, Mohammad Rahmati

“…Among various cardiovascular diseases, ischemic heart disease (IHD), the most prevalent pathological condition in human medicine, is induced by coronary artery narrowing, or occlusion, leading to bulk necrotic changes and fibrosis within the myocardium. Data associated with the pro-angiogenic activity of mitochondria have not been completely elucidated in terms of cardiac tissue regeneration. …”
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Effects of the Rho-Kinase Inhibitor Y-27632 on Extraocular Muscle Surgery in Rabbits by Ji‐Sun Moon, Hyun Kyung Kim, Sun Young Shin

“…Intraoperative subconjunctival injection of the Rho-kinase inhibitor may be effective for adjunctive management of inflammation and fibrosis in rabbit eyes following extraocular muscle surgery.…”
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Treatment of Urethral Strictures from Irradiation and Other Nonsurgical Forms of Pelvic Cancer Treatment by Iyad Khourdaji, Jacob Parke, Avinash Chennamsetty, Frank Burks

“…Obliterative endarteritis resulting in ischemia and fibrosis of the irradiated tissue complicates treatment strategies, which include urethral dilation, direct-vision internal urethrotomy (DVIU), urethral stents, and urethroplasty. …”
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Vaccination with an Attenuated Ferritin Mutant Protects Mice against Virulent Mycobacterium tuberculosis by Selvakumar Subbian, Ruchi Pandey, Patricia Soteropoulos, G. Marcela Rodriguez

“…We found that downmodulation of inflammatory response and enhanced fibrosis, compared to BCG vaccination, is associated with the protective response elicited by the bfrB mutant.…”
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Acquired Elliptocytosis as a Manifestation of Myelodysplastic Syndrome Associated with Deletion of Chromosome 20q by Sukesh Manthri, Naresh K. Vasireddy, Sindhura Bandaru, Swati Pathak

“…Bone marrow biopsy did not show significant fibrosis to explain the elliptocytosis. Cytogenetics showed 20q deletion, and later, he was started on therapy for intermediate risk MDS. …”
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Role of Neutrophil Extracellular Traps in Hypertension and Their Impact on Target Organs by Fei Yu, Jianshu Chen, Xiaowei Zhang, Zhengke Ma, Jingtao Wang, Qiang Wu

“…Inflammation is associated with the occurrence and progression of hypertension, but the underlying mechanism remains elusive, while chronic inflammation leads to tissue damage, fibrosis, and irreversible organ dysfunction. The development and maintenance of EH are caused by endothelial dysfunction, oxidative stress, and chronic inflammation. …”
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Insights into the diverse roles of the terminal oxidases in Burkholderia cenocepacia H111 by Sarah Paszti, Olivier Biner, Yilei Liu, Kim Bolli, Sarah Dorothy Jeggli, Gabriella Pessi, Leo Eberl

“…Abstract Burkholderia cenocepacia H111 is an obligate aerobic bacterium which has been isolated from a cystic fibrosis (CF) patient. In CF lungs the environment is considered micro-oxic or even oxygen-depleted due to bacterial activities and limited oxygen diffusion in the mucus layer. …”
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ABIN1 Inhibits Inflammation through Necroptosis-Dependent Pathway in Ulcerative Colitis by Jing Bao, Bin Ye, Yuhan Ren

“…Ulcerative colitis (UC) is characterized by chronic, recurrent intestinal inflammation and intestinal epithelial injury including a wide range of epithelial cell death, ulcers, crypt abscesses, and the formation of fibrosis. The intestinal barrier dysfunction runs through the whole process of the occurrence and development of UC. …”
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Karakteristik Pasien Sirosis Hepatis di RSUP Dr. M. Djamil Padang by Angela Lovena, Saptino Miro, Efrida Efrida

“…Sirosis hepatis didefinisikan sebagai penyakit hati kronik yang menyebabkan proses difus pembentukan nodul dan fibrosis pada hati. Di RSUP Dr. M. Djamil Padang sirosis hepatis merupakan salah satu penyakit terbanyak yang dirawat di Bagian Penyakit Dalam. …”
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Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren’s Syndrome by Go Makimoto, Michiko Asano, Nobukazu Fujimoto, Yasuko Fuchimoto, Katsuichiro Ono, Shinji Ozaki, Koji Taguchi, Takumi Kishimoto

“…Interstitial pulmonary fibrosis and tracheobronchial sicca are the most common symptoms of pulmonary involvement in primary SjS, and they are rarely accompanied by serositis such as pleuritis or pericarditis. …”
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The Expression of miR-192 and Its Significance in Diabetic Nephropathy Patients with Different Urine Albumin Creatinine Ratio by Xiaoyu Ma, Canlu Lu, Chuan Lv, Can Wu, Qiuyue Wang

“…These findings indicate that the levels of miR-192 were lower accompanied by the decrease of urine albumin creatinine ratio (UACR) and the association between miR-192 and nephritic fibrosis in DN.…”
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Generalized tuberculosis with long-term course in the guise of liver cirrhosis by Z. A. Lemeshko, M. V. Mayevskaya, I. N. Tikhonov, N. P. Musina, M. S. Zharkova, Ye. V. Fominykh, V. T. Ivashkin

“…It was possible to suspect and subsequently to confirm disseminated tuberculosis with involvement of the lungs, the heart, pericardium, pleura, mesenteric lymph nodes, the liver; chronic right-sided tubercular pleurisy with pleurocirrhosis; constrictive pericarditis with signs of right ventricular failure; cardiac liver fibrosis (Pick's pseudocirrhosis); mixed portal hypertension.Conclusion. …”
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Achyranthes bidentata Polysaccharide along with Anti-IL-5 Antibody Inhibits Allergic Lung Inflammation and Airway Hyperresponsiveness Mice Induced by House Dust Mites by Jian Sun, Shiwei Sheng, Gang Zhao

“…Products of eosinophils are considered as negative regulators that work on remodeling lung tissue, including airway thickening, fibrosis, and angiogenesis. Achyranthes bidentata polysaccharide (ABPS) is a kind of polysaccharide extracted from the dry root of Achyranthes plant Achyranthes bidentata. …”
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