Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia by O. E. O'Sullivan, D. Crosby, B. Byrne, C. Regan

“…As the disease is progressive all cases will develop portal fibrosis, cirrhosis, and portal hypertension with the sequelae of varices, jaundice, and eventually liver failure requiring a transplant. …”
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Ventricular Fibrillation following Varicella Zoster Myocarditis by Adam Ioannou, Irene Tsappa, Sofia Metaxa, Constantinos G. Missouris

“…He had a further collapse eight years later, and cardiac magnetic resonance imaging (MRI) demonstrated mild mid-wall basal and inferolateral wall fibrosis. He was treated with an implantable cardioverter defibrillator (ICD) and represented two years later with ICD shocks, and interrogation of the device revealed ventricular fibrillation episodes. …”
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Nanoexposure, Unusual Diseases, and New Health and Safety Concerns by Yuguo Song, Shichuan Tang

“…The reported disease was characterized by bilateral chest fluid, pulmonary fibrosis, pleural granuloma, and multiorgan damage and was highly associated with the nanoparticle exposure. …”
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An Unusual Cause of Spontaneous Pneumomediastinum: The Mounier-Kuhn Syndrome by Salim Naciri, Rachida Zahraoui, Mouna Soualhi, Jamal-Eddine Bourkadi

“…His chest computed tomographic scan showed a tracheobronchomegaly with an increase in the diameter of both the trachea and right and left main bronchi, associated with pneumomediastinum and fibrosis. Fiberoptic bronchoscopy revealed enlarged trachea and both main bronchi. …”
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Meconium Peritonitis and Periorchitis: Report of a Prenatal Case by Cem Yaşar Sanhal, İnanç Mendilcioğlu, Adnan Aslan, Murat Özekinci, Mehmet Şimşek

“…Meconium peritonitis may also be caused by viral infections (cytomegalovirus or parvovirus B19) and cystic fibrosis. Here, we report of a patient with fetal meconium peritonitis - periorchitis and perinatal management. …”
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Recent Developments in Sweat Analysis and Its Applications by Saima Jadoon, Sabiha Karim, Muhammad Rouf Akram, Abida Kalsoom Khan, Muhammad Abid Zia, Abdul Rauf Siddiqi, Ghulam Murtaza

“…Moreover, sweat comprises various biomarkers of different diseases including cystic fibrosis and diabetes. Additionally, the normalization of sampled volume of sweat is also necessary for getting efficient and useful results.…”
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The role of NF-κB in diabetic cardiomyopathy by Huang-Jun Liu, Le-Kun Gui, Han Wei, Xing-Yu Zhou, Zhen-Lan Liu, Li-Jun Jin

“…Among these, nuclear factor kappa B (NF-κB), a pleiotropic transcription factor, assumes a crucial role in regulating oxidative stress, inflammatory response, endothelial dysfunction, myocardial fibrosis and hypertrophy, and cardiomyocyte apoptosis in DCM. …”
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Cytokines as Therapeutic Targets for the Gastrointestinal Manifestations of Scleroderma by Jennifer M Raoul, Monica Verma, Ernest Tan, Theresa C Peterson

“…Systemic sclerosis (SSc), or scleroderma, is a connective tissue disorder characterized by progressive fibrosis of the skin and internal organs. It has significance for gastroenterologists because the gastrointestinal tract is involved in 90% of SSc patients, who often present with esophageal dysfunction. …”
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Occult Celiac Disease Associated with Lymphocytic Sclerosing Cholangitis by Hugh J Freeman, WC Peter Kwan

“…A liver biopsy done to explore persistently abnormal liver chemistry tests showed a portal tract-centred inflammatory process characterized by biliary ductal proliferation, epithelial lymphocytosis and concentric lamellar fibrosis. Quantitation of immunoglobulins was normal and antimitochondrial antibodies were negative. …”
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PL-7 Antisynthetase Syndrome in Association with Sjögren’s, Systemic Lupus Erythematosus, and Rheumatoid Arthritis by Mehrin Jawaid, Yael Ross, Mohammad Kamran

“…ILD was discovered after complaints of pleuritic chest pain with subsequent workup with coronary computed tomography (CT) revealing pulmonary fibrosis. This case demonstrates the ambiguity with which symptoms of ASS can present; given the high respiratory morbidity and mortality of ASS especially in non-Jo-1 patients, those who present with Raynaud’s, myositis, or joint pain, whether together or in isolation, should be assessed for presence of additional features of ASS and potentially undergo testing for ASS antibodies if appropriate.…”
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Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestation by Jayati Dave, Sunanda Mahajan, Ankita Maheshwari, Abhishek Gupta

“…Palmar fasciitis and polyarthritis syndrome is a rare disease characterized by palmar fasciitis, symmetric synovitis of the hands, fibrosis, and flexion contractures. We present a case of a 48-year-old female who presented with complaints of bilateral contracture of hands with diffuse hyperpigmentation over body folds, face, and trunk suggestive of MAN. …”
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Colistin: The phoenix Arises by JM Conly, BL Johnston

“…As a result, the use of polymyxin preparations has been mainly restricted to the treatment of lung infections due to multidrug-resistant (MDR) gram-negative bacteria in patients with cystic fibrosis (6,7). The emergence of bacteria resistant to most classes of commercially available antibiotics and the shortage of novel antimicrobial agents with activity against gram-negative microorganisms have led to the reemergence of polymyxins as a valuable addition to the therapeutic armamentarium. …”
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Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases by Junio Dort, Paul Fabre, Thomas Molina, Nicolas A. Dumont

“…Particularly, the transition of macrophages from their proinflammatory to their anti-inflammatory phenotype was shown to regulate inflammation, myogenesis, fibrosis, vascularization, and return to homeostasis. …”
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Pegilated interferon alpha 2b «Pegaltevir» chronic hepatitis C treatment (randomized clinical trial) by Marina V. Mayevskaya, Ye. N. Bessonova, P. O. Bogomolov, N. I. Geyvandova, K. V. Zhdanov, V. G. Morozov, V. D. Pasechnikov, I. Yu. Khomenko, A. V. Yagoda, V. T. Ivashkin

“…No significant differences between basic and control groups at analysis of paired liver biopsies for fibrosis stage reduction rate, absence of negative changes for fibrosis severity and proportion of patients with fibrosis progression were found. …”
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Hubungan Kadar Trigliserida dan Kolesterol-HDL Terhadap Kadar Alanine Aminotransferase pada Pasien Non Alcoholic Fatty Liver Disease by Bayu Gemilang, Yanwirasti ., Saptino Miro

“…NAFLD merupakan penyakit hati kronik yang nantinya dapat menyebabkan fibrosis sel-sel hepar dan juga keganasan. NAFLD tidak menunjukkan manifestasi klinis yang khas, sehingga diperlukan pemeriksaan penunjang seperti pemeriksaan enzim hati untuk menegakkan diagnosis. …”
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Development of delayed pulmonary toxicities and transcriptional changes in pre-existing interstitial lung disease mice after partial thoracic irradiation by Jiamei Fu, Xinglong Liu, Yuchuan Zhou, Shengnan Zhao, Liang Zeng, Yan Pan, Jianghong Zhang, Kevin M. Prise, Chunlin Shao, Yaping Xu

“…DAD with progressive inflammation and fibrosis in bilateral lungs contributed to severe or even fatal complications after partial thoracic irradiation. …”
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Elevated Serum Levels of the Antiapoptotic Protein Decoy-Receptor 3 Are Associated with Advanced Liver Disease by Giorgos Bamias, Michalis Gizis, Ioanna Delladetsima, Eyfrosyni Laoudi, Spyros I. Siakavellas, Ioannis Koutsounas, Garyfallia Kaltsa, John Vlachogiannakos, Irene Vafiadis-Zouboulis, George L. Daikos, George V. Papatheodoridis, Spiros D. Ladas

“…In patients with CVH, sDcR3 significantly correlated to fibrosis severity, as estimated by Ishak score (P=0.019) or by liver stiffness measured with elastography (Spearman r=0.698, P<0.001). …”
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Exendin-4 Improves Diabetic Kidney Disease in C57BL/6 Mice Independent of Brown Adipose Tissue Activation by Shu Fang, Yingying Cai, Fuping Lyu, Hongbin Zhang, Chunyan Wu, Yanmei Zeng, Cunxia Fan, Shaozhou Zou, Yudan Zhang, Ping Li, Ling Wang, YaomingXue, Meiping Guan

“…The weight, blood glucose and lipids, 24 h urine albumin and 8-OH-dG, and renal fibrosis were analyzed. In vitro, we investigated the role of exendin-4 in the differentiation process of 3T3-L1 and brown preadipocytes and its effect on the rat mesangial cells induced by oleate. …”
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Schistosoma japonicum Infection in Treg-Specific USP21 Knockout Mice by Youxiang Zhang, De-Hui Xiong, Yangyang Li, Guina Xu, Baoxin Zhang, Yang Liu, Shan Zhang, Qing Huang, Simin Chen, Fansheng Zeng, Jingyi Guo, Bin Li, Zhiqiang Qin, Zuping Zhang

“…USP21 may have potential for regulating hepatic fibrosis in patients with schistosomiasis.…”
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Interplay of PNPLA3 and HSD17B13 Variants in Modulating the Risk of Hepatocellular Carcinoma among Hepatitis C Patients by Carla De Benedittis, Mattia Bellan, Martina Crevola, Elena Boin, Matteo Nazzareno Barbaglia, Venkata Ramana Mallela, Paolo Ravanini, Elisa Ceriani, Stefano Fangazio, Pier Paolo Sainaghi, Michela Emma Burlone, Rosalba Minisini, Mario Pirisi

“…Carriage of PNPLA3 G∗ allele was associated with a trend of progressively more severe liver disease, from mild fibrosis to significant fibrosis, cirrhosis, and HCC (p=0.007). …”
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