An Unusual Mechanism of Closure of Muscular Ventricular Septal Defects by Soham Dasgupta, Ashraf M. Aly

“…The usual mechanism of spontaneous closure involves muscular tissue encroachment with superimposed fibrosis or primary fibrous tissue formation around the margins of the defect. …”
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Chronic Disease Management in Children Based on the Five Domains of Health by Wing Lung Alvin So

“…Through a case study of a child with cystic fibrosis, the interactions among various domains of health have been discussed—namely, biomedical, physical, psychological/behavioural, and social. …”
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Combined Bile Duct and Pancreatic Duct Injuries during Distal Gastrectomy for Obstructing Peptic Ulcer Disease by Narendra Pandit, Kunal Bikram Deo

“…Anomalous ductal anatomy, distorting duodenal fibrosis, and pancreatic atrophy predispose to this untoward complication during performance of distal gastrectomy for benign peptic stricture. …”
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15-Deoxy-Δ12,14-Prostaglandin J2 Inhibits Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury via Redox Pathway by Xin Liu, Shuangshuang Jia, Weiyang Li, Le Yang, Lin Yang, Lin Wang, Liying Li

“…In conclusion, our results suggest that 15d-PGJ2 plays a crucial role in homing of BMSCs to the injured liver dependent on ROS production, independently of PPARγ, which may represent a new strategy in the treatment of liver fibrosis.…”
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Caracterización de los pacientes con bradiarritmias atendidos en el servicio de Cardiología de Cienfuegos (2018-2019) by Samuel Sánchez Sánchez, Magdiel Echazabal Leal, Ana Laura Navarro Baldellot, Emmanuel Sánchez Ramos

“…Fueron causas principales de la bradiarritmia no reversible, la fibrosis del sistema excito-conductor y la isquémica.…”
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Synergic Renoprotective Effects of Combined ASC Therapy with RAAS Blockade in Experimental Advanced CKD by Marina P. C. Maires, Krislley R. Pereira, Everidiene K. V. B. Silva, Victor H. R. Souza, Flavio Teles, Paulyana F. Barbosa, Margoth R. Garnica, Felipe M. Ornellas, Irene L. Noronha, Camilla Fanelli

“…Overactivity of the renin-angiotensin-aldosterone system (RAAS), associated to renal inflammation and fibrosis, contributes to its evolution. The treatments currently employed to control CKD progression are limited and mainly based on the pharmacological inhibition of RAAS, associated with diuretics and immunosuppressive drugs. …”
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Fungsi Tiroid Pasca Radioterapi Tumor Ganas Kepala- Leher by Ade Chandra, Sukri Rahman

“…Kelainan pada tiroid pasca radioterapi dihubungkan dengan kerusakan sel dan pembuluh darah kecil kelenjar tiroid serta fibrosis kapsul kelenjar tiroid yang selanjutnya menyebabkan kelenjar tiroid mengecil. …”
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Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity by Caitlin V. Lewis, Antony Vinh, Henry Diep, Chrishan S. Samuel, Grant R. Drummond, Barbara K. Kemp-Harper

“…Thus, M2 macrophage-derived ROS is identified as a potentially important contributor to aortic fibrosis.…”
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A comprehensive analysis of percutaneous liver biopsy characteristics and pathological manifestations in a large patient cohort (2009–2024) by Minling Cao, Jiayi Zeng, Jiayu Wang, Junmin Jiang

“…Patients with hepatitis B complicated by MASLD exhibited disease exacerbation in middle age, with both liver inflammation and fibrosis grading worsening as age advanced. Furthermore, within the same age bracket, the severity of inflammation and the extent of fibrosis were more pronounced in cases where chronic hepatitis B was combined with MASLD compared to those with isolated chronic hepatitis B or MASLD. …”
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Practical Aspects of Clinical Manifestations, Pathogenesis and Therapy of Alcoholic Liver Disease and Non-alcoholic Fatty Liver Disease: Expert Opinion by V. V. Tsukanov, M. F. Osipenko, E. V. Beloborodova, M. A. Livzan, I. B. Khlynov, S. A. Alekseenko, Yu. P. Sivolap, J. L. Tonkikh, A. V. Vasyutin

“…For the diagnosis of liver pathology, it is important to determine the stage of fibrosis and the severity of the exacerbation of the disease. …”
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Ameliorative Impact of Liraglutide on Chronic Intermittent Hypoxia-Induced Atrial Remodeling by Jun Wang, Yongzheng Liu, Changhui Ma, Yue Zhang, Meng Yuan, Guangping Li

“…The CIH group exhibited significant AR, increased atrial fibrosis, and a higher incidence rate of AF compared to the control group. …”
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Targeted Plasma Bile Acid Metabolomic Analysis in Metabolic Dysfunction-Associated Steatohepatitis and Alcoholic Hepatitis by Yuta Hirata, Yasunaru Sakuma, Hideo Ogiso, Ryozo Nagai, Kenichi Aizawa

“…Aspartate aminotransferase (AST) showed strong positive correlations with TCDCA and GCDCA. Child–Pugh score, Fibrosis-4 index, and non-alcoholic fatty liver disease fibrosis score were positively correlated with GCA, whereas the aspartate aminotransferase-to-platelet ratio correlated with TCA, TCDCA, and GCA. …”
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A systematic review and meta-analysis assessing adverse event profile and tolerability of nicergoline by Amit Garg, Jun Xu, Mario Fioravanti, Taku Nakashima

“…None of the studies included in this systematic review reported any incidence of fibrosis or ergotism with nicergoline.…”
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Erosive Arthritis, Fibromatosis, and Keloids: A Rare Dermatoarthropathy by Fawad Aslam, Jonathan A. Flug, Yousif Yonan, Shelley S. Noland

“…Polyfibromatosis is a rare disease characterized by fibrosis manifesting in different locations. It is commonly characterized by palmar fibromatosis (Dupuytren’s contracture) in variable combinations with plantar fibromatosis (Ledderhose’s disease), penile fibromatosis (Peyronie’s disease), knuckle pads, and keloids. …”
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Role of NKT Cells in the Pathogenesis of NAFLD by Kazuto Tajiri, Yukihiro Shimizu

“…NKT cells may have a protective role at the early stage with simple steatosis through modification of insulin resistance, whereas they act as a progression factor at the advanced stage with fibrosis. Those processes are thought to depend on interaction between NKT cells and CD1d molecule in the liver.…”
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Endothelial-Mesenchymal Transition in Regenerative Medicine by Damian Medici

“…Endothelial-mesenchymal transition (EndMT) is a fundamental cellular mechanism that regulates embryonic development and diseases such as cancer and fibrosis. Recent developments in biomedical research have shown remarkable potential to harness the EndMT process for tissue engineering and regeneration. …”
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A Severe Complication of Crack Cocaine Use by Gokul Vidyasankar, Carolina Souza, Chi Lai, Sunita Mulpuru

“…Serial imaging revealed progressive interstitial fibrosis secondary to recurrent alveolar hemorrhage and inflammation from crack cocaine. …”
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Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa by Astrid-Helene Ravn Jørgensen, Yiqiu Yao, Simon Francis Thomsen

“…It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).…”
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Chemoradiation-Induced Superior Vena Cava Syndrome: A Case Report by Mathieu Castonguay, George Rodrigues, Mark Vincent, Richard A Malthaner, Lin-Ruo Guo

“…A case of a 54-year-old man who developed superior vena cava syndrome secondary to vascular fibrosis, 30 months after radical chemoradiation for stage III non-small cell lung cancer, is presented. …”
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Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy by Xiao-Li Chen, Yu-Jing Bai, Qin-Rui Hu, Shan-Shan Li, Lv-Zhen Huang, Xiao-Xin Li

“…EMT markers and related inflammatory and fibrosis cytokines were measured by western blot or flow cytometry. …”
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